scholarly journals Comorbidities on kidney transplantation waiting list relative to the status of the potential recipient

2016 ◽  
Author(s):  
Jolanta Malyszko ◽  
Teresa Dryl-Rydzynska ◽  
Wojciech Marcinkowski ◽  
Tomasz Prystacki ◽  
Jacek S. Malyszko
Keyword(s):  
Kidney Transplantation ◽  
Waiting List ◽  
The Status ◽  
Potential Recipient

scholarly journals A survey of waiting lists for kidney transplantation in northeastern Iran

2020 ◽  
Vol 5 (2) ◽  
pp. e20-e20
Author(s):  
Majid Jangi ◽  
Hamed Tabesh ◽  
Mahin Ghorban Sabbagh ◽  
Ebrahim Khaleghi Baigi ◽  
Sayyed Mostafa Mostafavi ◽  
...  
Keyword(s):  
Kidney Transplantation ◽  
Waiting List ◽  
Unknown Etiology ◽  
Time Period ◽  
The Status ◽  
Linkage Method ◽  
Stage Renal Disease ◽  
Clinical Records ◽  
End Stage ◽  
Esrd Patients

Introduction: End-stage renal disease (ESRD) continues to be a public health challenge. In ESRD patients, renal replacement therapy is essential. Kidney transplantation is considered as an effective therapeutic procedure for ESRD. On the advice of a qualified nephrologist, ESRD patients are registered on a waiting list, seeking organ transplantation. Objectives: This study aimed to report the status of the waiting list for kidney transplantation in the northeastern Iran region, with data covering the time period until 2017. Patients and Methods: The study was conducted at Montaserie hospital in Mashhad, Iran. We reviewed the clinical records of all ESRD patients referred to the hospital, retrospectively. Patients’ data were completed using a data linkage method and analyzed using SPSS version 23. Results: A total of 1956 patients were studied from the waiting list with a mean age of 44.7 ± 14.4 years (3-80 years). The described etiology reveals that the main causes of ESRD were unknown sources (44.1%), diabetes (18.4%) and hypertension (10.9%). Hemodialysis therapy was conducted for 91.1% of the patients. The maximum registered waiting time was 295 months and the minimum was one month, with an average of 63 months. The proportion of patients waiting for the first, second and third kidney transplantation was 86%, 13.2% and 0.7%, respectively. Conclusion: This study highlights that in the population under study, the number of registered patients on the waiting list followed an increasing pattern, while the age of patients decreased. Unfortunately, in most case studies in Iran, the true etiology of nephrology diseases is still unknown. More effort to define the ESRD causes is necessary. The most likely reason for reported cases with unknown etiology is delays in referral problems.

P1550ACCESS TO KIDNEY TRANSPLANTATION IN A NON-PROFIT FACILITY IN GERMANY

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Stephan Kemmner ◽  
Wolfgang Arns ◽  
Gero Von Gersdorff ◽  
Rolf Dieter Bach ◽  
Michael Fischereder
Keyword(s):  
Kidney Transplantation ◽  
Waiting List ◽  
Dialysis Treatment ◽  
Non Profit ◽  
For Profit ◽  
The Status ◽  
Dialysis Facility ◽  
Transplant Evaluation ◽  
Stage Renal Disease ◽  
End Stage

Abstract Background and Aims Recent studies demonstrate that US patients undergoing chronic dialysis treatment for end stage renal disease (ESRD) at for-profit facilities had a lower access to kidney transplantation than patients at non-profit facilities. However, even at non-profit facilities only around 20% of patients were placed on the kidney transplantation waiting list. At first glance, this number appears rather low, as kidney transplantation is the only way to curatively treat ESRD. We want to compare these figures with a recently performed survey in Germany. Method We analyzed the status of transplant evaluation in the largest non-profit facility in Germany, the Kuratorium für Dialyse und Nierentransplantation e.V. (kfh, www.kfh.de). In total, the transplant status was assessed in 16,705 patients. Results Out of these only 19.4% of patients (n=3241) are on the kidney transplant waiting list, comparable to recently performed US studies. The reason why patients are not waitlisted are multifaceted as seen in attached figure. Due to severe comorbidities about 50% are considered too sick to benefit from transplantation, in turn representing the complex and high multi-morbidity of patients with ESRD. On the other hand, approximately 10% of dialysis patients actively decline listing for renal transplantation at least at some point. Conclusion We conclude that further research is needed to identify and break the mechanisms behind the low likelihood for access to kidney transplantation waiting list. Distribution of patients with surveyed transplant status in the largest non-profit dialysis facility (kfh, www.kfh.de) in Germany

scholarly journals COVID-19—Importance for Patients on the Waiting List and after Kidney Transplantation—A Single Center Evaluation in 2020–2021

Pathogens ◽  
2021 ◽  
Vol 10 (4) ◽  
pp. 429
Author(s):  
Simone C. Boedecker ◽  
Pascal Klimpke ◽  
Daniel Kraus ◽  
Stefan Runkel ◽  
Peter R. Galle ◽  
...  
Keyword(s):  
Kidney Transplantation ◽  
Waiting List ◽  
Smoking History ◽  
Immunocompromised Patients ◽  
Dialysis Patients ◽  
Vaccination Programs ◽  
Mild Disease ◽  
Probability Of Survival ◽  
Number Of Patients ◽  
Immunosuppressed Patients

(1) Background: Dialysis patients and recipients of a kidney allograft are at high risk for infection with SARS-CoV-2. It has been shown that the development of potent neutralizing humoral immunity against SARS CoV-2 leads to an increased probability of survival. However, the question of whether immunocompromised patients develop antibodies has not yet been sufficiently investigated; (2) Methods: SARS-CoV-2 antibodies were examined in hemodialysis patients on the waiting list for kidney transplantation as well as patients after kidney transplantation. Patients were interviewed about symptoms and comorbidities, BMI, and smoking history; (3) Results: SARS-CoV-2 antibodies were found in 16 out of 259 patients (6%). The trend of infections here reflects the general course of infection in Germany with a peak in November/December of 2020. Remarkably, patients on the waiting list experienced only mild disease. In contrast, transplanted patients had to be hospitalized but recovered rapidly from COVID-19. Most interesting is that all immunosuppressed patients developed antibodies against SARS-CoV-2 after infection; (4) Conclusions: Even with extensive hygiene concepts, an above-average number of patients were infected with SARS-CoV-2 during the second wave of infections in Germany. Because SARS-CoV-2 infection triggered the formation of antibodies even in these immunocompromised patients, we expect vaccination to be effective in this group of patients. Thus, dialysis patients and patients after kidney transplantation should be given high priority in vaccination programs.

A time-series analysis of the U.S. kidney transplantation and the waiting list: donor substitution effects

2010 ◽  
Vol 42 (1) ◽  
pp. 261-277 ◽  
Author(s):  
T. Randolph Beard ◽  
John D. Jackson ◽  
David Kaserman ◽  
Hyeongwoo Kim
Keyword(s):  
Time Series ◽  
Kidney Transplantation ◽  
Time Series Analysis ◽  
Waiting List ◽  
Substitution Effects ◽  
Series Analysis ◽  
The U.S

scholarly journals A Comparison of Different Algorithms for the Assessment of Cardiovascular Risk in Patients at Waiting List for Kidney Transplantation

PLoS ONE ◽  
2016 ◽  
Vol 11 (10) ◽  
pp. e0161927 ◽  
Author(s):  
Stefan Reuter ◽  
Stefanie Reiermann ◽  
Viola Malyar ◽  
Katharina Schütte-Nütgen ◽  
Renè Schmidt ◽  
...  
Keyword(s):  
Kidney Transplantation ◽  
Cardiovascular Risk ◽  
Waiting List

scholarly journals Ranking patients on the kidney transplant waiting list based on fuzzy inference system

2022 ◽  
Vol 23 (1) ◽  
Author(s):  
Nasrin Taherkhani ◽  
Mohammad Mehdi Sepehri ◽  
Roghaye Khasha ◽  
Shadi Shafaghi
Keyword(s):  
Kidney Transplantation ◽  
Fuzzy Inference System ◽  
Scoring System ◽  
Fuzzy Inference ◽  
Waiting List ◽  
Analytic Hierarchy ◽  
Inference System ◽  
Kidney Allocation ◽  
Single Output ◽  
Stage Renal Disease

Abstract Background Kidney transplantation is the best treatment for people with End-Stage Renal Disease (ESRD). Kidney allocation is the most important challenge in kidney transplantation process. In this study, a Fuzzy Inference System (FIS) was developed to rank the patients based on kidney allocation factors. The main objective was to develop an expert system, which would mimic the expert intuitive thinking and decision-making process in the face of the complexity of kidney allocation. Methods In the first stage, kidney allocation factors were identified. Next, Intuitionistic Fuzzy Analytic Hierarchy Process (IF-AHP) has been used to weigh them. The purpose of this stage is to develop a point scoring system for kidney allocation. Fuzzy if-then rules were extracted from the United Network for Organ Sharing (UNOS) dataset by constructing the decision tree, in the second stage. Then, a Multi-Input Single-Output (MISO) Mamdani fuzzy inference system was developed for ranking the patients on the waiting list. Results To evaluate the performance of the developed Fuzzy Inference System for Kidney Allocation (FISKA), it was compared with a point scoring system and a filtering system as two common approaches for kidney allocation. The results indicated that FISKA is more acceptable to the experts than the mentioned common methods. Conclusion Given the scarcity of donated kidneys and the importance of optimal use of existing kidneys, FISKA can be very useful for improving kidney allocation systems. Countries that decide to change or improve the kidney allocation system can simply use the proposed model. Furthermore, this model is applicable to other organs, including lung, liver, and heart.

Failure to Advance Access to Kidney Transplantation over Two Decades in the United States

2021 ◽  
Vol 32 (4) ◽  
pp. 913-926
Author(s):  
Jesse D. Schold ◽  
Sumit Mohan ◽  
Anne Huml ◽  
Laura D. Buccini ◽  
John R. Sedor ◽  
...  
Keyword(s):  
United States ◽  
Kidney Transplantation ◽  
The United States ◽  
Waiting List ◽  
Adult Patients ◽  
Policy Reforms ◽  
Cox Models ◽  
Longitudinal Pattern ◽  
Dialysis Facilities ◽  
Over Time

BackgroundExtensive research and policies have been developed to improve access to kidney transplantation among patients with ESKD. Despite this, wide variation in transplant referral rates exists between dialysis facilities.MethodsTo evaluate the longitudinal pattern of access to kidney transplantation over the past two decades, we conducted a retrospective cohort study of adult patients with ESKD initiating ESKD or placed on a transplant waiting list from 1997 to 2016 in the United States Renal Data System. We used cumulative incidence models accounting for competing risks and multivariable Cox models to evaluate time to waiting list placement or transplantation (WLT) from ESKD onset.ResultsAmong the study population of 1,309,998 adult patients, cumulative 4-year WLT was 29.7%, which was unchanged over five eras. Preemptive WLT (prior to dialysis) increased by era (5.2% in 1997–2000 to 9.8% in 2013–2016), as did 4-year WLT incidence among patients aged 60–70 (13.4% in 1997–2000 to 19.8% in 2013–2016). Four-year WLT incidence diminished among patients aged 18–39 (55.8%–48.8%). Incidence of WLT was substantially lower among patients in lower-income communities, with no improvement over time. Likelihood of WLT after dialysis significantly declined over time (adjusted hazard ratio, 0.80; 95% confidence interval, 0.79 to 0.82) in 2013–2016 relative to 1997–2000.ConclusionsDespite wide recognition, policy reforms, and extensive research, rates of WLT following ESKD onset did not seem to improve in more than two decades and were consistently reduced among vulnerable populations. Improving access to transplantation may require more substantial interventions.

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