scholarly journals Systematic review/Meta-analysis Computed tomography for detecting left atrial thrombus: a meta-analysis

2012 ◽  
Vol 6 ◽  
pp. 943-951 ◽  
Author(s):  
Xiaosan Wu ◽  
Congxia Wang ◽  
Chunyan Zhang ◽  
Yan Zhang ◽  
Faming Ding ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Systematic Review ◽  
Left Atrial ◽  
Meta Analysis ◽  
Left Atrial Thrombus ◽  
Atrial Thrombus

scholarly journals Plasma fibrin D-dimer and the risk of left atrial thrombus: A systematic review and meta-analysis

PLoS ONE ◽  
2017 ◽  
Vol 12 (2) ◽  
pp. e0172272 ◽  
Author(s):  
Huaibin Wan ◽  
Shuang Wu ◽  
Yanmin Yang ◽  
Jun Zhu ◽  
Aidong Zhang ◽  
...  
Keyword(s):  
Systematic Review ◽  
Left Atrial ◽  
Meta Analysis ◽  
Left Atrial Thrombus ◽  
Atrial Thrombus ◽  
D Dimer

21 Cardiac computed tomography for assessment of left atrial thrombus in patients undergoing TAVI

Heart ◽  
2016 ◽  
Vol 102 (Suppl 4) ◽  
pp. A11.1-A11
Author(s):  
Sonny Palmer ◽  
Mark de Belder ◽  
Douglas Muir ◽  
Paul Williams
Keyword(s):  
Computed Tomography ◽  
Left Atrial ◽  
Cardiac Computed Tomography ◽  
Left Atrial Thrombus ◽  
Atrial Thrombus

Computed Tomography as a Superior Diagnostic Test for Left Atrial Thrombus With Calcification

2019 ◽  
Vol 108 (3) ◽  
pp. e175-e177
Author(s):  
Lei Pu ◽  
Yingjie Zhang ◽  
Yan Liu ◽  
Boyu Liu ◽  
Yingnan Yang ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Diagnostic Test ◽  
Left Atrial ◽  
Left Atrial Thrombus ◽  
Atrial Thrombus

scholarly journals Diagnostic accuracy of D-dimer to detect left atrial thrombus in patients with atrial fibrillation: a systematic review and meta-analysis

2021 ◽  
Vol 42 (Supplement_1) ◽  
Author(s):  
C Diaz-Arocutipa ◽  
A.C Gonzales-Luna ◽  
A Branez-Condorena ◽  
A.V Hernandez
Keyword(s):  
Atrial Fibrillation ◽  
Diagnostic Accuracy ◽  
Left Atrial ◽  
Meta Analysis ◽  
Characteristic Curve ◽  
Left Atrial Thrombus ◽  
Summary Receiver Operating Characteristic ◽  
Atrial Thrombus ◽  
Cross Sectional ◽  
D Dimer

Abstract Background There is limited evidence on the use of biomarkers to diagnose left atrial thrombus in atrial fibrillation. Purpose We evaluated the diagnostic accuracy of D-dimer to detect left atrial thrombus in patients with atrial fibrillation. Methods We searched four electronic databases from inception to December 16, 2020 for observational studies evaluating diagnostic accuracy of D-dimer. Reference standard was left atrial thrombus detected by transesophageal echocardiography. Study quality was assessed with the QUADAS-2 tool. We performed a bivariate random-effects meta-analysis to calculate the pooled sensitivity and specificity with their 95% confidence intervals (95% CI). In addition, a summary receiver operating characteristic curve and optimal cut-off were estimated. Results Eleven cross-sectional studies involving 4380 patients were included. The mean age ranged from 49.8 to 74.1 years and 70% of patients were men. Left atrial thrombus was present in 7% of cases. In seven studies, the pooled sensitivity of D-dimer at 500 ng/mL was 53% (95% CI, 26–79%) and the pooled specificity was 92% (95% CI, 80–97%). The pooled sensitivity of age-adjusted D-dimer was 35% (95% CI, 18–57%) and the pooled specificity was 100% (95% CI, 100–100%) in two studies. The optimal cut-off was 390 ng/mL in 10 studies with a pooled sensitivity of 68% (95% CI, 44–85%) and a pooled specificity of 73% (95% CI, 54–86%). The risk of bias was low or unclear for all domains. Concerns regarding applicability were generally low for almost all studies Conclusion Our meta-analysis suggests that D-dimer has the potential to be useful to the detection of left atrial thrombus in patients with atrial fibrillation. FUNDunding Acknowledgement Type of funding sources: None.

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