scholarly journals Number and size of acquired melanocytic nevi and affecting risk factors in cases admitted to the dermatology clinic

2016 ◽  
Vol 5 ◽  
pp. 375-380
Author(s):  
Ayşegül Yalçınkaya İyidal ◽  
Ülker Gül ◽  
Arzu Kılıç
Keyword(s):  
Risk Factors ◽  
Melanocytic Nevi ◽  
Dermatology Clinic

A screening checklist to minimize the adverse effects of cosmetic dermatological procedures; a short paper (Preprint)

2021 ◽  
Author(s):  
Sanjeewani Fonseka ◽  
Sewwandi Abeyrathna
Keyword(s):  
Risk Factors ◽  
Adverse Effects ◽  
The Other ◽  
Short Paper ◽  
Full Understanding ◽  
External Appearance ◽  
Increase Patient Satisfaction ◽  
Dermatology Clinic ◽  
Screening Guideline ◽  
Remedial Actions

BACKGROUND Cosmetic dermatological procedures which are aimed at enhancing the external appearance have troublesome yet preventable adverse effects. At present, there is a lack of a comprehensive screening guideline to detect patients with risk factors for such adverse effects. OBJECTIVE To introduce a comprehensive screening checklist to pick up the patients’ risk factors in advance, in order to prevent or minimize adverse effects from cosmetic dermatological procedures. METHODS The checklist was administered to 1150 patients attending an outpatient dermatology clinic for cosmetic dermatological procedures. Checklist composed of 30 ‘yes/no’ type questions and 7 other components in the pre-procedure workup. RESULTS Except for two risk factors (being pregnant and having a pacemaker inserted), all other assessed possible risk factors were present in one or more patients who attended for procedures. The most prevalent risk factor was the current use of medications in 226 (19.65%) patients. The other commonly found risk factors were: lack of full understanding of the procedure (14.52%) and phobia/fear of injections (9.30%). CONCLUSIONS The screening checklist that we used is a simple yet comprehensive tool for minimizing the possible adverse effects of cosmetic dermatological procedures. We were able to postpone, take remedial actions or alter the cosmetic dermatological procedures after going through the checklist and increase patient satisfaction and improve the safety of the doctor as well. CLINICALTRIAL Not applicable

Do Biologics Protect Patients With Psoriasis From Myocardial Infarction? A Retrospective Cohort

2016 ◽  
Vol 20 (6) ◽  
pp. 536-541 ◽  
Author(s):  
Wayne P. Gulliver ◽  
Shane Randell ◽  
Susanne Gulliver ◽  
Sean Connors ◽  
Hervé Bachelez ◽  
...  
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Retrospective Cohort ◽  
Biologic Therapy ◽  
Age Of Onset ◽  
Significant Risk ◽  
Severe Psoriasis ◽  
Inflammatory Disorder ◽  
Dermatology Clinic ◽  
Increased Risk

Background: Psoriasis is a chronic immune-mediated inflammatory disorder that affects approximately 2% to 3% of the population, which translates to 17 million in North America and Europe and approximately 170 million people worldwide. Although psoriasis can occur at any age, most cases develop before age 40 years. Some larger studies have noted bimodal age at onset with the first peak occurring at approximately age 30 years and the second peak at around 55 to 60 years, but most patients have a younger age of onset (15-30 years). Psoriasis is associated with multiple comorbidities, decreased quality of life, and decreased longevity of life. Two recent systematic reviews and a meta-analysis concluded that psoriasis patients are at increased risk of major adverse cardiovascular events. Multiple studies confirm that many of the comorbidities found in patients with psoriasis are also important risk factors for cardiovascular disease, stroke, diabetes mellitus, hypertension, hyperlipidemia, obesity, and metabolic syndrome. Methods: We conducted a retrospective cohort study using charts from a dermatology clinic combined with an administrative database of patients with moderate to severe psoriasis in Newfoundland and Labrador, Canada. We examined the role of clinical predictors (age of onset of psoriasis, age, sex, biologic use) in predicting incident myocardial infarction (MI). Results: Logistic regression revealed that age of onset (odds ratio [OR], 8.85; P = .005), advancing age (OR, 1.07; P < .0001), and being male (OR, 3.64; P = .018) were significant risk factors for the development of MI. Neither biologic therapy nor duration of biologic therapy were statistically significant risk factors for the development of MI. Our study found that in patients with psoriasis treated with biologics, there was a nonsignificant trend in reduced MI by 78% (relative risk, 0.18; 95% confidence interval, 0.24-1.34; P = .056). Conclusion: Our study demonstrated a trend toward decreased MI in patients with moderate to severe psoriasis on biologics. Patients with an early age of onset of psoriasis (<25 years) were nearly 9 times more likely to have an MI. Clinicians should consider appropriate cardiovascular risk reduction strategies in patients with psoriasis.

Facial Location and Operating Room Environment are the Risk Factors for Incomplete Excision of Melanocytic Nevi

2018 ◽  
Vol 29 (05) ◽  
pp. 458-461
Author(s):  
Oskar Zgraj ◽  
Anna Taczanowska-Niemczuk ◽  
Wojciech Gorecki
Keyword(s):  
Risk Factors ◽  
Operating Room ◽  
Surgical Oncology ◽  
P Value ◽  
Anatomical Location ◽  
Chi Square ◽  
Melanocytic Nevi ◽  
Incomplete Excision ◽  
Number Of Patients ◽  
Chi Square Test

Introduction The management of melanocytic nevi involves many various practitioners with a high number of patients. Data on failure to achieve goals of treatment are scarce. We aimed to determine percentage of incompletely excised nevi and the risk factors responsible. Materials and Methods In this retrospective cohort study, histology reports of all melanocytic nevi excised within our department between January 2014 and June 2015 were considered. Those aimed for stage excision and those with inconclusive histology reports were excluded. Patients' age, sex, anatomical location of the lesion, its size, as well as source of specimen (general surgical outpatients, surgical oncology outpatients, and operating room), and performing surgeon (trainee vs. consultant) were recorded. Chi-square test was used for statistical analysis with a p-value of < 0.05 considered significant. Results A total of 739 nevi in 541 patients were analyzed. Positive margins were found in 80 (11%) of all specimens. There was significantly increased rate of incomplete excision of nevi from the facial area (42%; p < 0.001) versus other areas and, surprisingly, those excised in the operating room under general anesthesia (19%; p = 0.009). Nevi excised at our surgical oncology outpatients had the lowest rate (8%, p = 0.013) of incomplete excisions. There were no statistically significant differences in other variables. Conclusion We identified facial location and operating room environment as risk factors for incomplete excision of melanocytic nevi. We suggest that human factors play a key role in achieving a good quality of service.

scholarly journals Risk factors of incident melanocytic nevi: A longitudinal study in a cohort of 1,232 young German children

2005 ◽  
Vol 115 (1) ◽  
pp. 121-126 ◽  
Author(s):  
Jürgen Bauer ◽  
Petra Büttner ◽  
Tine Sander Wiecker ◽  
Heike Luther ◽  
Claus Garbe
Keyword(s):  
Risk Factors ◽  
Longitudinal Study ◽  
Melanocytic Nevi ◽  
German Children

Melanoma, melanocytic nevi, and other melanoma risk factors in children

1994 ◽  
Vol 124 (6) ◽  
pp. 833-845 ◽  
Author(s):  
Mary L. Williams ◽  
Raffaelle Pennella
Keyword(s):  
Risk Factors ◽  
Melanoma Risk ◽  
Melanocytic Nevi

scholarly journals Genital Warts Among Men Attending a Dermatology Clinic: Risk Factors and Knowledge

2020 ◽  
Vol 9 (3) ◽  
Author(s):  
Nasrin Motazedian ◽  
Mehrab Sayadi ◽  
Shohreh Beheshti
Keyword(s):  
Risk Factors ◽  
Young Male ◽  
Sexual Relationships ◽  
Sex Partners ◽  
Extramarital Relationships ◽  
Sexually Transmitted ◽  
Dermatology Clinic ◽  
Public Health Challenge ◽  
The Mean ◽  
Collection Form

: Human papillomavirus (HPV) is one of the most common sexually transmitted infections, with the highest prevalence among young adults. We investigated the risk factors of this infection among men. A total of 224 men referred to a dermatology clinic in Shiraz to treat anogenital warts from June 2015 till Feb 2016 were enrolled. Data collection form included demographic characteristics and risk factors. The participants’ mean age was 28.84 ± 8 years, and half of them (54.5%) were in the second decade of their life. Nearly half of them were single, 110 (49.1%), and 103 had high education (48.4%). Among our participants, the mean age of sexual relationship onset was 20.31 ± 3.71; 69 (60.5%) of the married participants had experienced sexual intercourse before marriage, and 58 (61.05%) had extramarital sexual relationships. The mean number of sex partners was 2.8. More than half of the participants (n = 146, 66.4%) were not aware of STI symptoms. Our participants were young, and more than half of the married ones had extramarital relationships. Altogether, low awareness of STI symptoms was seen. HPV could be a public health challenge in our young male adults because of their risk factors and lack of knowledge.

scholarly journals The Incidence of Scabies and Head Lice and Their Associated Risk Factors among Displaced People in Cham Mishko Camp, Zakho City, Duhok Province, Iraq

2020 ◽  
Vol 69 (4) ◽  
pp. 463-469
Author(s):  
MOHAMMAD I. ALBERFKANI ◽  
WIJDAN M.S. MERO
Keyword(s):  
Risk Factors ◽  
Care Center ◽  
Weather Data ◽  
Head Lice ◽  
Carriage Rate ◽  
Internally Displaced ◽  
Health Care Center ◽  
Dermatology Clinic ◽  
Displaced People ◽  
Associated Risk Factors

This study was conducted to estimate the incidence and the effects of associated risk factors of scabies and head lice on displaced people in Cham Mishko camp, Zakho city, Duhok Province, Iraq. The study included 1300 internally displaced people (IDPs) who visited the dermatology clinic and health care center in Cham Mishko camp from January 2018 to December 2019. Participants’ bio-information was collected on special questionnaire form after receiving permission from the camp’s health authorities and verbal consent from the participants. Monthly weather data were collected from Duhok Directorate of Meteorology and Seismology. The total rate of ectoparasites was 81.2% (45% for scabies and 36.2% for head lice). Ages from 1–10, 21–30, and 31–40 years showed the highest rates with scabies (48.1%, 46.7% and 46.1%, respectively), while the highest rates of head pediculosis were at ages from 1–10 and 11–20 years (40% and 36.6%, respectively). Scabies rate was slightly higher in males than females (46.6% vs. 43.4%), while the rate of head pediculosis was significantly higher in females than males (58.2% vs. 13.9%). Families with more than ten people showed the highest rates of scabies and head pediculosis (49.5% and 74.5%). Scabies was more common in cold months than in summer while head pediculosis was more common in hot months. The number of scabies and head pediculosis cases increased by 123 and 85 cases, respectively, in 2019. It is inferred that the effects of scabies and head pediculosis in IDPs will be considerable, with a higher carriage rate than other studies in Iraq.

Elevated level of circulatory sTLT1 induces inflammation through SYK/MEK/ERK signalling in coronary artery disease

2019 ◽  
Vol 133 (22) ◽  
pp. 2283-2299
Author(s):  
Apabrita Ayan Das ◽  
Devasmita Chakravarty ◽  
Debmalya Bhunia ◽  
Surajit Ghosh ◽  
Prakash C. Mandal ◽  
...  
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Chronic Inflammation ◽  
Ex Vivo ◽  
Human Subjects ◽  
Critical Role ◽  
Atherosclerotic Cardiovascular Disease ◽  
Tnf Α ◽  
Artery Disease

Abstract The role of inflammation in all phases of atherosclerotic process is well established and soluble TREM-like transcript 1 (sTLT1) is reported to be associated with chronic inflammation. Yet, no information is available about the involvement of sTLT1 in atherosclerotic cardiovascular disease. Present study was undertaken to determine the pathophysiological significance of sTLT1 in atherosclerosis by employing an observational study on human subjects (n=117) followed by experiments in human macrophages and atherosclerotic apolipoprotein E (apoE)−/− mice. Plasma level of sTLT1 was found to be significantly (P<0.05) higher in clinical (2342 ± 184 pg/ml) and subclinical cases (1773 ± 118 pg/ml) than healthy controls (461 ± 57 pg/ml). Moreover, statistical analyses further indicated that sTLT1 was not only associated with common risk factors for Coronary Artery Disease (CAD) in both clinical and subclinical groups but also strongly correlated with disease severity. Ex vivo studies on macrophages showed that sTLT1 interacts with Fcɣ receptor I (FcɣRI) to activate spleen tyrosine kinase (SYK)-mediated downstream MAP kinase signalling cascade to activate nuclear factor-κ B (NF-kB). Activation of NF-kB induces secretion of tumour necrosis factor-α (TNF-α) from macrophage cells that plays pivotal role in governing the persistence of chronic inflammation. Atherosclerotic apoE−/− mice also showed high levels of sTLT1 and TNF-α in nearly occluded aortic stage indicating the contribution of sTLT1 in inflammation. Our results clearly demonstrate that sTLT1 is clinically related to the risk factors of CAD. We also showed that binding of sTLT1 with macrophage membrane receptor, FcɣR1 initiates inflammatory signals in macrophages suggesting its critical role in thrombus development and atherosclerosis.

Sign in / Sign up

Export Citation Format

Share Document