scholarly journals Perspective: A note on the advantages of large scale monitoring as in the global monitoring plan (GMP) on persistent organic pollutants (POPs)

2012 ◽  
Vol 3 (4) ◽  
pp. 369-370
Author(s):  
Ramon Guardans
2013 ◽  
Vol 5 (1) ◽  
pp. 185-232
Author(s):  
Tahnee Lisa Prior

Abstract We often mistakenly assume that institutional design will remain effective indefinitely. Complex long-term environmental challenges illuminate the disparity between institutions and state boundaries. While globalization has challenged monocentrism, we must look beyond traditional measures and design resilient governance systems, such as polycentric governance, that combine trust and local expertise in small-scale governance with the governance capacity of large-scale systems. These harness globalization’s benefits and provide solutions for the effects of ecosystem changes. This work examines the lessons – benefits, challenges, limitations, and unanswered questions – that may be learned from polycentric governance in the case of Persistent Organic Pollutants (POPs) in the Arctic, where a polycentric political system has developed as a result of a mismatch in environmental, jurisdictional, and temporal scales. Section One examines characteristics of polycentricity, focusing on actors, multilevel governance, degree of formality, and the nature of interactions. Section Two concentrates on the tools utilized. Section Three applies the outlined framework. Finally, Section Four examines three lessons that global environmental governance may learn from the case study: (1) Peak organizations are effective tools for managing polycentricity, allowing for the inclusion of non-state actors, such as indigenous peoples organizations (2) and epistemic communities (3), in bridging the human-environment nexus.


2021 ◽  
pp. 227-252
Author(s):  
Kanchan Kumari ◽  
Senerita Swamy ◽  
Anshika Singh

2004 ◽  
Vol 11 (2) ◽  
pp. 157-163 ◽  
Author(s):  
Jennifer C. C. Neale ◽  
Thomas P. Kenny ◽  
M. Eric Gershwin

Protein kinases (PKs) play critical roles in signal transduction and activation of lymphocytes. The identification of PK genes provides a tool for understanding mechanisms of immunotoxic xenobiotics. As part of a larger study investigating persistent organic pollutants in the harbor seal and their possible immunomodulatory actions, we sequenced harbor seal cDNA fragments encoding PKs. The procedure, using degenerate primers based on conserved motifs of human protein tyrosine kinases (PTKs), successfully amplified nine phocid PK gene fragments with high homology to human and rodent orthologs. We identified eight PTKs and one dual (serine/threonine and tyrosine) kinase. Among these were several PKs important in early signaling events through the B- and T-cell receptors (FYN, LYN, ITK and SYK) and a MAP kinase involved in downstream signal transduction. V-FGR, RET and DDR2 were also expressed. Sequential activation of protein kinases ultimately induces gene transcription leading to the proliferation and differentiation of lymphocytes critical to adaptive immunity. PKs are potential targets of bioactive xenobiotics, including persistent organic pollutants of the marine environment; characterization of these molecules in the harbor seal provides a foundation for further research illuminating mechanisms of action of contaminants speculated to contribute to large-scale die-offs of marine mammals via immunosuppression.


2018 ◽  
Vol 2 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Tee L. Guidotti

On 16 October 1996, a malfunction at the Swan Hills Special Waste Treatment Center (SHSWTC) in Alberta, Canada, released an undetermined quantity of persistent organic pollutants (POPs) into the atmosphere, including polychlorinated biphenyls, dioxins, and furans. The circumstances of exposure are detailed in Part 1, Background and Policy Issues. An ecologically based, staged health risk assessment was conducted in two parts with two levels of government as sponsors. The first, called the Swan Hills Study, is described in Part 2. A subsequent evaluation, described here in Part 3, was undertaken by Health Canada and focused exclusively on Aboriginal residents in three communities living near the lake, downwind, and downstream of the SHSWTC of the area. It was designed to isolate effects on members living a more traditional Aboriginal lifestyle. Aboriginal communities place great cultural emphasis on access to traditional lands and derive both cultural and health benefits from “country foods” such as venison (deer meat) and local fish. The suspicion of contamination of traditional lands and the food supply made risk management exceptionally difficult in this situation. The conclusion of both the Swan Hills and Lesser Slave Lake studies was that although POPs had entered the ecosystem, no effect could be demonstrated on human exposure or health outcome attributable to the incident. However, the value of this case study is in the detail of the process, not the ultimate dimensions of risk. The findings of the Lesser Slave Lake Study have not been published previously and are incomplete.


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