scholarly journals Cognitive Functions of Bipolar Disorder Patients in Remission on Monotherapy: A Follow-Up Study

2017 ◽  
Author(s):  
Vesile Cankorur Senturk ◽  
Hilal Demirel ◽  
Damla Yucel ◽  
Sibel Cakir ◽  
Sermin Kesebir ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Cognitive Functions ◽  
Follow Up Study

Changes in oral and cognitive functions among older Japanese dental outpatients: A 2‐year follow‐up study

2021 ◽  
Author(s):  
Shinsuke Mizutani ◽  
Rui Egashira ◽  
Masahiro Yamaguchi ◽  
Keiko Tamai ◽  
Mizuki Yoshida ◽  
...  
Keyword(s):  
Cognitive Functions ◽  
Follow Up Study

ALDH2 modulated changes in cytokine levels and cognitive function in bipolar disorder: A 12-week follow-up study

2017 ◽  
Vol 52 (7) ◽  
pp. 680-689
Author(s):  
Sheng-Yu Lee ◽  
Tzu-Yun Wang ◽  
Shiou-Lan Chen ◽  
Yun-Hsuan Chang ◽  
Po-See Chen ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Cognitive Function ◽  
Growth Factor ◽  
Transforming Growth Factor ◽  
Transforming Growth Factor Β1 ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Follow Up Study ◽  
Cytokine Levels

Objectives: We investigated the association of the aldehyde dehydrogenase 2 ( ALDH2) polymorphism (rs671), which is involved with the dopaminergic function, and with changes in cytokine levels and cognitive function, in a 12-week follow-up study in patients with bipolar disorder. Methods: Patients with a first diagnosis of bipolar disorder were recruited. Symptom severity and levels of plasma cytokines (tumor necrosis factor α, C-reactive protein, interleukin 6 and transforming growth factor β1) were examined during weeks 0, 1, 2, 4, 8 and 12. Neurocognitive function was evaluated at baseline and endpoint. The ALDH2 polymorphism genotype was determined. Results: A total of 541 patients with bipolar disorder were recruited, and 355 (65.6%) completed the 12-week follow-up. A multiple linear regression analysis showed a significant ( p = 0.000226) association between the ALDH2 polymorphism and changes in C-reactive protein levels. Different aspects of cognitive function improved in patients with different ALDH2 genotypes. Only patients with the ALDH2*1*1 genotype showed significant correlations between improvement of cognitive function and increased transforming growth factor -β1. Conclusion: The ALDH2 gene might influence changes in cytokine levels and cognitive performance in patients with bipolar disorder. Additionally, changes in cytokine levels and cognitive function were correlated only in patients with specific ALDH2 genotypes.

Metabolic syndrome in Italian patients with bipolar disorder: A 2-year follow-up study

2012 ◽  
Vol 136 (3) ◽  
pp. 599-603 ◽  
Author(s):  
Virginio Salvi ◽  
Virginia D'Ambrosio ◽  
Filippo Bogetto ◽  
Giuseppe Maina
Keyword(s):  
Metabolic Syndrome ◽  
Bipolar Disorder ◽  
Follow Up Study
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