Juvenile rheumatoid arthritis (Juvenile chronic arthritis)

2001 ◽  
Vol 7 (2) ◽  
Author(s):  
Macrene Alexiades-Armenakas
Keyword(s):  
Rheumatoid Arthritis ◽  
Juvenile Rheumatoid Arthritis ◽  
Juvenile Chronic Arthritis ◽  
Chronic Arthritis

Juvenile Rheumatoid Arthritis

1980 ◽  
Vol 2 (6) ◽  
pp. 163-174
Author(s):  
Jane G. Schaller
Keyword(s):  
Rheumatoid Arthritis ◽  
Juvenile Rheumatoid Arthritis ◽  
English Literature ◽  
Juvenile Chronic Arthritis ◽  
The United States ◽  
Chronic Arthritis ◽  
Adult Type ◽  
Childhood Arthritis ◽  
Distinct Disease ◽  
Sick Children

Juvenile rheumatoid arthritis is the condition of chronic synovitis in children. This Condition was first well described in the English literature by George Frederick Still,1 an English pediatrician and pathologist, who in 1897 described 22 children with chronic arthritis who had come to his attention while he was still in training at the Hospital for Sick Children, Great Ormond Street. Still postulated that several distinct conditions were responsible for chronic arthritis in children. After Still, unfortunately, little work was done in the field of pediatric rheumatology until recent years. Most modern observers have come to agree with Still that chronic arthritis in children encompasses several distinct disease subgroups.2-5 The relationship of juvenile rheumatoid arthritis to adult rheumatoid arthritis remains uncertain; some of the subgroups described in children are not recognized in adults, whereas classic adult-type rheumatoid arthritis occurs in children, but accounts for only a small percentage of total patients.4 The nomenclature for chronic childhood arthritis is quite confusing at the present time (Table 1). The term juvenile rheumatoid arthritis (JRA) has been retained in the United States to describe all children with chronic arthritis, whereas the term juvenile chronic arthritis is becoming more widely used in Europe. The term Still disease, although according due honor to an important person, is confusing and should probably be discarded.

Juvenile idiopathic arthritis

2011 ◽  
pp. 303-320
Author(s):  
Alan J. Hakim ◽  
Gavin P.R. Clunie ◽  
Inam Haq
Keyword(s):  
Rheumatoid Arthritis ◽  
Juvenile Idiopathic Arthritis ◽  
Rheumatoid Factor ◽  
Juvenile Rheumatoid Arthritis ◽  
Juvenile Chronic Arthritis ◽  
Chronic Arthritis ◽  
Juvenile Arthritis ◽  
Childhood Onset ◽  
International League

Introduction 304 Oligoarthritis 306 Systemic arthritis 310 Rheumatoid factor negative polyarthritis in childhood 316 Chronic, infantile, neurological, cutaneous, and articular syndrome 319 • The classification of childhood onset arthritis has seen several changes over recent years. In this chapter we will discuss juvenile arthritis using headings and criteria from the International League of Associations for Rheumatology (ILAR.) The terms ‘juvenile rheumatoid arthritis’ (JIA) and ‘juvenile chronic arthritis’ (JCA) were discarded in the ILAR classification. The term ‘juvenile idiopathic arthritis’ was adopted to indicate arthritis present for at least 6 weeks and currently of no known cause in a patient <16 years....

scholarly journals Anti-tumor necrosis factor α switching in rheumatoid arthritis and juvenile chronic arthritis

2004 ◽  
Vol 51 (2) ◽  
pp. 301-302 ◽  
Author(s):  
Ennio Giulio Favalli ◽  
Marco Arreghini ◽  
Cristina Arnoldi ◽  
Benedetta Panni ◽  
Antonio Marchesoni ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Tumor Necrosis Factor ◽  
Tumor Necrosis ◽  
Tumor Necrosis Factor Α ◽  
Juvenile Chronic Arthritis ◽  
Chronic Arthritis ◽  
Factor Α ◽  
Necrosis Factor

scholarly journals Identification of Mycoplasma fermentans in Synovial Fluid Samples from Arthritis Patients with Inflammatory Disease

2000 ◽  
Vol 38 (1) ◽  
pp. 90-93
Author(s):  
Sheena Johnson ◽  
David Sidebottom ◽  
Felix Bruckner ◽  
David Collins
Keyword(s):  
Rheumatoid Arthritis ◽  
Synovial Fluid ◽  
Inflammatory Cells ◽  
Juvenile Chronic Arthritis ◽  
Chronic Arthritis ◽  
Proteinase K ◽  
16S Rrna Genes ◽  
Rrna Genes ◽  
Mycoplasma Species ◽  
Mycoplasma Fermentans

ABSTRACT Since 1970 Mycoplasma fermentans has been suspected of being associated with rheumatoid arthritis. However, this association has been difficult to prove, and this has been our goal. The distribution of M. fermentans was studied in the synovial fluid of patients suffering from different arthritides. Samples of synovial fluid were taken from patients with well-defined disease and a clear diagnosis. After removal of the inflammatory cells and hyaluran, they were treated with proteinase K and tested by a single or fully nested PCR with primers directed against part of the two 16S rRNA genes of M. fermentans . The product was sequenced automatically, by using an ALF Express automatic sequencer, to confirm the mycoplasma species and to identify the strain since the two genes were usually found to be polymorphic. This was also true of the type strain, strain PG18. M. fermentans was detected in 23 of 26 (88%) rheumatoid arthritis patients, and four different strains were found. It was also found in 7 of 8 (88%) of the nonrheumatoid inflammatory arthritis patient group, which consisted of one patient with reactive arthritis, one patient with pauciarticular juvenile chronic arthritis, two patients with gout, two patients with ankylosing spondylitis, and two patients with psoriatic arthritis, only one of whom was infected with M. fermentans . It was not detected in any of the 10 osteoarthritis patients. M. fermentans was therefore found to be a variable and very common organism in arthritic patients with inflammatory joint exudates and may well prove to be important in the etiology of the diseases.

scholarly journals The p53 status in juvenile chronic arthritis and rheumatoid arthritis

2000 ◽  
Vol 122 (2) ◽  
pp. 264-269 ◽  
Author(s):  
H. Taubert ◽  
B. Thamm ◽  
A. Meye ◽  
F. Bartel ◽  
A.-K. Rost ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Juvenile Chronic Arthritis ◽  
Chronic Arthritis ◽  
P53 Status
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