scholarly journals Superimposed Non-acid Reflux Event: An Example of When It May Be Important to Revisit the Impedance Analysis Guidelines

2022 ◽  
Vol 28 (1) ◽  
pp. 165-166
Author(s):  
Frederick W Woodley
Keyword(s):  
Impedance Analysis ◽  
Acid Reflux ◽  
Reflux Event

Time to Stop Blaming Gastroesophageal Reflux

2011 ◽  
Vol 50 (12) ◽  
pp. 1110-1115 ◽  
Author(s):  
Jose M. Garza ◽  
Cade M. Nylund ◽  
Ajay Kaul
Keyword(s):  
Gastroesophageal Reflux ◽  
Retrospective Review ◽  
Acid Reflux ◽  
Acid Suppression ◽  
Multichannel Intraluminal Impedance ◽  
Children's Hospital ◽  
Intraluminal Impedance ◽  
Nonacid Reflux ◽  
Reflux Event ◽  
Children’S Hospital

Objectives. Cough, pain, and desaturation episodes in infants are often ascribed to gastroesophageal reflux, and many are empirically treated with acid suppression medications. The authors hypothesize that most of these symptoms are not related to gastroesophageal reflux. Methods. Retrospective review of 186 combined pH–multichannel intraluminal impedance studies performed in infants at Cincinnati Children’s Hospital. Results. Of 4159 symptoms reported 1504 (36%) were associated with reflux events (27% nonacid and 9% acid). When total number of symptoms and reflux events were taken into consideration, nonacid reflux events were as likely to be associated with a symptom as acid reflux events ( P = .66). Conclusion. The extra-esophageal symptoms commonly attributed to gastroesophageal reflux in infants are most often not associated with a reflux event. Even though causality cannot be definitively proven, in the minority in whom a symptom association is observed, nonacid events are as likely as acid events to cause symptoms.

Comparison of Sensed Acid Reflux Event Characteristics among the Different GERD Groups

2007 ◽  
Vol 102 ◽  
pp. S133-S134
Author(s):  
Ron Schey ◽  
Tomas Navarro-Rodriguez ◽  
Michael Shapiro ◽  
Christopher Wendel ◽  
Ronnie Fass
Keyword(s):  
Acid Reflux ◽  
Reflux Event

scholarly journals Diagnostic Efficacy of 24-hr Esophageal pH Monitoring in Patients with Refractory Gastroesophageal Reflux Disease

2018 ◽  
Vol 6 (7) ◽  
pp. 1235-1238 ◽  
Author(s):  
Atoosa Gharib ◽  
Mojgan Forootan ◽  
Marjan Sharifzadeh ◽  
Saied Abdi ◽  
Mohammad Darvishi ◽  
...  
Keyword(s):  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Reflux Disease ◽  
Ph Monitoring ◽  
Impedance Analysis ◽  
Acid Reflux ◽  
Diagnostic Efficacy ◽  
Weakly Acid ◽  
Refractory Gerd ◽  
Acid Acid

BACKGROUND: Gastric reflux is one of the most important causes of the referral of patients to the internal clinic, which in some cases causes problems for patients due to resistance to common treatments. Therefore, timely diagnosis and treatment of this group of patients are very important.AIM: The purpose of the present study was to determine the off-proton pump inhibitor (off-PPI) 24 h pH-impedance analyses in patients with refractory gastroesophageal reflux disease (GERD) attending to Taleghani Hospital since 2009 to 2017.METHODS: In this observational descriptive-comparative off-PPI study, 572 patients with refractory GERD who were referred to Taleghani Hospital in Tehran from 2009 to 2017 were selected, and the results of 24 h pH Impedance analysis were then assessed.RESULTS: The results of 24h pH-impedance indicated that 7% of cases belonged to Pure Acid Reflux followed by weakly Acid (1%), non-acid (0.3%), mixed & gas (5.2%), functional (58.4%) and oesophagal hypersensitivity (28%). Furthermore, weakly acid plus acid was also found to be 8% and Weakly Acid + Acid + Non-Acid were determined as 8.3%.CONCLUSIONS: Our findings suggested that nearly more than half of the patients with refractory GERD would have a functional disorder in the 24h pH-impedance analysis.

scholarly journals Is belching increasing after bariatric bypass surgery in the long term period?

2021 ◽  
Vol 84 (4) ◽  
pp. 601-605
Author(s):  
F Akyüz ◽  
B Göksoy ◽  
P Telli ◽  
N Nizam ◽  
A Atasoy ◽  
...  
Keyword(s):  
Gastric Bypass ◽  
Bypass Surgery ◽  
Gastric Bypass Surgery ◽  
Gastrointestinal Symptoms ◽  
Impedance Analysis ◽  
Acid Reflux ◽  
Mini Gastric Bypass ◽  
Demeester Score ◽  
Symptom Association Probability

Background and aims: Gastric bypass surgery effectively treats obesity; however, its association with belching, which occurs in other bariatric surgeries, remains unclear. Hence, we aimed to evaluate belching occurrence after gastric bypass surgery. Methods: We enrolled 12 healthy volunteers and 17 patients (12 and 5 underwent Roux-en-Y gastric bypass and mini-gastric bypass surgeries 24 (18–54) months prior, respectively). Gastrointestinal symptoms were assessed. Gastroscopy was performed, followed by the 24-hour pH-impedance analysis. Results: Age and sex were not statistically different between the two groups (P > 0.05). Patients had a significantly higher mean DeMeester score than the healthy controls (9.11 ± 19.40 vs. 6.04 ± 5.60, P = 0.048), but the pathologic acid reflux (DeMeester score > 14) rate was similar in both groups (11.8% vs. 8.3%). Regarding the impedance, symptom-association probability was positive in 11.8% of patients. The patients also had higher alkaline reflux rates (6% vs. 0%); additionally, 50% of them experienced belching based on the questionnaire, and 25% had esophagitis based on gastroscopy. Furthermore, patients had a significantly higher number of gas reflux (123.24 ± 80 vs. 37.2 ± 21.5, P = 0.001) and supragastric/ gastric belches (182 ± 64/228 ± 66.69 vs. 25.08 ± 15.20/12.17 ± 17.65, P = 0.001). Supragastric belching was more frequent than gastric belching in the controls, whereas gastric belching was more frequent in the patients. Conclusion: Belching increases after gastric bypass surgery in a long-term period. Gastric belching was more frequent than supragastric belching in these patients.

Combined Multi-channel Intraluminal Impedance and pH Testing Compared to pH Testing Alone for Diagnosing Gastro-esophageal Acid Reflux

2008 ◽  
Vol 59 (2) ◽  
pp. 126-128
Author(s):  
K. Adachi ◽  
K. Koshino ◽  
T. Morita ◽  
H. Nakata ◽  
T. Tanimura ◽  
...  
Keyword(s):  
Acid Reflux ◽  
Intraluminal Impedance
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