scholarly journals Transient Anal Sphincter Relaxations Are a Normal Phenomenon in Healthy Subjects: Author‘s Reply

2020 ◽  
Vol 26 (4) ◽  
pp. 554-555
Author(s):  
Tae Hee Lee
Keyword(s):  
Anal Sphincter ◽  
Healthy Subjects

scholarly journals Manometric Evaluation of Internal Anal Sphincter after Fissurectomy and Anoplasty for Chronic Anal Fissure: A Prospective Study

2012 ◽  
Vol 78 (5) ◽  
pp. 523-527 ◽  
Author(s):  
Rosalia Patti ◽  
Valentina Territo ◽  
Paolo Aiello ◽  
Giuseppe Livio Angelo ◽  
Gaetano Di Vita
Keyword(s):  
Postoperative Complications ◽  
Anal Fissure ◽  
Anal Sphincter ◽  
Anal Incontinence ◽  
Internal Anal Sphincter ◽  
Healthy Subjects ◽  
Chronic Anal Fissure ◽  
Skin Flap ◽  
Anal Continence ◽  
Squeeze Pressure

Chronic anal fissure (CAF) is a common painful clinical disease and its pathogenesis remains poorly understood. After failure of pharmacological therapy, that is the first-line treatment, surgical sphincterotomy remains the treatment of choice although it is followed by a high rate of anal incontinence resulting from the sphincter damage; therefore, the research of a sphincter-saving surgical option has become an important goal. The aim of this study was to evaluate the manometric modifications and the incidence of anal incontinence after fissurectomy and anoplasty with advancement skin flap in patients affected by CAF with hypertonia of the internal anal sphincter (IAS). Fifteen patients affected by CAF with hypertonia of IAS, unresponsive to medical therapy, were enrolled. All subjects underwent fissurectomy and anoplasty with advancement skin flap. Anorectal manometry was performed preoperatively and after 6 and 12 months from surgery. Maximum resting pressure (MRP), maximum squeeze pressure (MSP), ultraslow wave activity (USWA), fissure healing, anal continence, and postoperative complications were recorded. All patients healed within 30 days from surgery. No intra- or postoperative complications were recorded except for a case of partial donor site break. No significant modifications of MSP were detected. Six months after surgery, MRP was higher with respect to healthy subjects but significantly reduced in comparison to baseline levels. At 12 months, it was higher have versus 6-month values but significantly lower versus preoperative values. USWA was significantly represented in patients with CAF versus healthy subject. Both at 6 and 12 months, they decreased significantly with respect to preoperative values without significant differences versus healthy subjects. Both at 6 and 12 months, anal continence did not differ with respect to preoperative time. The fissurectomy with anoplasty resulted in a high healing rate without surgical sequelae or anal incontinence. Also, it was able to reduce IAS pressure in the same manner as surgical sphincterotomy or forceful dilatation.

scholarly journals Transient Anal Sphincter Relaxations Are a Normal Phenomenon in Healthy Subjects

2020 ◽  
Vol 26 (4) ◽  
pp. 552-553
Author(s):  
Jan D Huizinga ◽  
Natalija Milkova ◽  
Ji-Hong Chen
Keyword(s):  
Anal Sphincter ◽  
Healthy Subjects

Effect of rectal distension on voluntary external anal sphincter function in healthy subjects

2011 ◽  
Vol 13 (10) ◽  
pp. 1173-1179 ◽  
Author(s):  
A. Bajwa ◽  
K. Thiruppathy ◽  
P. Trivedi ◽  
P. Boulos ◽  
A. Emmanuel
Keyword(s):  
Anal Sphincter ◽  
Healthy Subjects ◽  
External Anal Sphincter ◽  
Rectal Distension ◽  
Sphincter Function ◽  
Anal Sphincter Function

Reflex Responses in Upper Limb Muscles to Cutaneous Stimuli

1993 ◽  
Vol 20 (04) ◽  
pp. 271-278 ◽  
Author(s):  
R. Chen
Keyword(s):  
Stimulus Intensity ◽  
Upper Limb ◽  
Healthy Subjects ◽  
Voluntary Contraction ◽  
Cutaneous Reflexes ◽  
Focal Lesions ◽  
Normal Ranges ◽  
Conduction Velocities ◽  
Limb Muscles ◽  
Biphasic Responses

ABSTRACT:Cutaneous reflexes in the upper limb were elicited by stimulating digital nerves and recorded by averaging rectified EMG from proximal and distal upper limb muscles during voluntary contraction. Distal muscles often showed a triphasic response: an inhibition with onset about 50 ms (Il) followed by a facilitation with onset about 60 ms (E2) followed by another inhibition with onset about 80 ms (12). Proximal muscles generally showed biphasic responses beginning with facilitation or inhibition with onset at about 40 ms. Normal ranges for the amplitude of these components were established from recordings on 22 arms of 11 healthy subjects. An attempt was made to determine the alterent fibers responsible for the various components by varying the stimulus intensity, by causing ischemic block of larger fibers and by estimating the afferent conduction velocities. The central pathways mediating these reflexes were examined by estimating central delays and by studying patients with focal lesions

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