scholarly journals Efficacy of acotiamide on postprandial distress syndrome and epigastric pain syndrome depending on the estimated gastric acid secretion level

2021 ◽  
Author(s):  
Toshiaki Suzuki ◽  
Reina Ohba ◽  
Ei Kataoka ◽  
Yui Kudo ◽  
Akira Zeniya ◽  
...  
Keyword(s):  
Acid Secretion ◽  
Gastric Acid Secretion ◽  
Gastric Acid ◽  
Distress Syndrome ◽  
Epigastric Pain ◽  
Pain Syndrome ◽  
Postprandial Distress Syndrome ◽  
Epigastric Pain Syndrome

scholarly journals The effect of acotiamide on epigastric pain syndrome and postprandial distress syndrome in patients with functional dyspepsia

2016 ◽  
Vol 63 (3.4) ◽  
pp. 230-235 ◽  
Author(s):  
Satoshi Shinozaki ◽  
Hiroyuki Osawa ◽  
Hirotsugu Sakamoto ◽  
Yoshikazu Hayashi ◽  
Alan Kawarai Lefor ◽  
...  
Keyword(s):  
Functional Dyspepsia ◽  
Distress Syndrome ◽  
Epigastric Pain ◽  
Pain Syndrome ◽  
Postprandial Distress Syndrome ◽  
Epigastric Pain Syndrome

scholarly journals Prevalence, risk factors, and ethnic characteristics of uninvestigated dyspepsia

2020 ◽  
Vol 4 (5) ◽  
pp. 263-267
Author(s):  
V.V. Tsukanov ◽  
◽  
A.V. Vasyutin ◽  
Yu.L. Tonkikh ◽  
◽  
...  
Keyword(s):  
Risk Factors ◽  
Helicobacter Pylori ◽  
Rural Areas ◽  
Distress Syndrome ◽  
Epigastric Pain ◽  
Pain Syndrome ◽  
Endoscopic Examination ◽  
Postprandial Distress Syndrome ◽  
Epigastric Pain Syndrome ◽  
Rome Iv

Background: in our country, studies on the prevalence of dyspepsia performed using the Rome IV criteria are rare, which makes it difficult to objectively compare Russian and international data, including ethnic characteristics. Aim: to study the prevalence and risk factors of uninvestigated dyspepsia in indigenous and foreign residents in rural areas of the Republic of Khakassia. Patients and Methods: continuous epidemiological screening (coverage 93.4%) of dyspepsia was performed in the villages Matur, Anchul, Verchnii Kurlugash, Nizhnie Siry, Bolshoy Bor, Bolshaya Seya, Verkhnyaya Seya, Inchul, Verkhnii Tashtyp of the Tashtyp district. A total of 2,080 newly-arrived residents (Caucasians, 911 males, average age 43.6 years) and 2,117 indigenous residents (Khakas, 978 males, average age 42.9 years) were surveyed. Dyspepsia was studied in accordance with the recommendations of the Rome IV criteria. Epigastric pain syndrome and postprandial distress syndrome were distinguished. Due to the fact that endoscopic examination of patients was not used, dyspepsia was considered as uninvestigated dyspepsia. The presence of Helicobacter pylori was determined serologically in 566 Caucasians and 533 Khakas. The results of clinical examination and interview (social status, complaints, medical history) were recorded in the standard questionnaires. Results: uninvestigated dyspepsia was diagnosed in 24.6% of Caucasians and 19.2% of Khakas (p<0.001). Gender did not affect the prevalence of dyspepsia in Khakas. Among Caucasians, there was a tendency to more common detection of dyspepsia in women. The pain variant of dyspepsia prevailed in men in both populations. The incidence of postprandial distress syndrome among Caucasians was significantly higher in women. Other risk factors for dyspepsia in both populations were the following: age older than 50, Helicobacter pylori infection, smoking 20 or more cigarettes per day for more than 10 years, history of gallbladder pathology, acute viral hepatitis and helminthiasis. Conclusion: the data obtained allow to consider the influence of ethnicity on the prevalence of uninvestigated dyspepsia, including depending on gender identity. KEYWORDS: uninvestigated dyspepsia, ethnic characteristics, Helicobacter pylori, prevalence, risk factors. FOR CITATION: Tsukanov V.V., Vasyutin A.V., Tonkikh Yu.L. Prevalence, risk factors, and ethnic characteristics of uninvestigated dyspepsia. Russian Medical Inquiry. 2020;4(5):264–267. DOI: 10.32364/2587–6821–2020–4-5-263-267.

scholarly journals Functional Dyspepsia: Subtypes, Risk Factors, and Overlap with Irritable Bowel Syndrome in a Population of African Patients

2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Sylvester Chuks Nwokediuko ◽  
Uchenna Ijoma ◽  
Olive Obienu
Keyword(s):  
Risk Factors ◽  
Irritable Bowel Syndrome ◽  
Functional Dyspepsia ◽  
Distress Syndrome ◽  
Epigastric Pain ◽  
Pain Syndrome ◽  
Postprandial Distress Syndrome ◽  
Epigastric Pain Syndrome ◽  
Irritable Bowel ◽  
African Patients

Background. Functional dyspepsia is the prototype functional gastrointestinal disorder. This study was designed to determine its prevalence, subtypes, and risk factors associated with the subtypes.Method. Patients with upper gastrointestinal symptoms who presented for endoscopy were administered a questionnaire containing the functional dyspepsia and irritable bowel syndrome modules of the Rome III diagnostic criteria.Results. Of 192 patients who had functional dyspepsia, epigastric pain syndrome, postprandial distress syndrome, and combination of the two subtypes accounted for 79.2%, 62.5%, and 50%, respectively. Multivariate analysis of the risk factors showed that independent predictors of postprandial distress syndrome were alcohol and irritable bowel syndrome while irritable bowel syndrome was independent predictor of epigastric pain syndrome. Alcohol, smoking, and use of nonsteroidal anti-inflammatory drugs were independent predictors of cooccurrence of postprandial distress syndrome and epigastric pain syndrome.Conclusion. Functional dyspepsia accounts for 62.5% of dyspepsia in a population of black African patients. Regarding symptomatology, epigastric pain syndrome, postprandial distress syndrome, and combination of the two subtypes account for 79.2%, 62.5%, and 50%, respectively. Risk factors for functional dyspepsia are irritable bowel syndrome, alcohol, smoking, and use of nonsteroidal anti-inflammatory drugs.

903 Impaired Accommodation Is a Feature of Functional Dyspepsia Patients with Postprandial Distress Syndrome, Not with Epigastric Pain Syndrome

2009 ◽  
Vol 136 (5) ◽  
pp. A-140-A-141 ◽  
Author(s):  
Sebastien Kindt ◽  
Raf Bisschops ◽  
Rita Vos ◽  
Lieselot Holvoet ◽  
Philip Caenepeel ◽  
...  
Keyword(s):  
Functional Dyspepsia ◽  
Distress Syndrome ◽  
Epigastric Pain ◽  
Pain Syndrome ◽  
Postprandial Distress Syndrome ◽  
Epigastric Pain Syndrome

Prevalence and pathophysiology of post-prandial migraine in patients with functional dyspepsia

Cephalalgia ◽  
2019 ◽  
Vol 39 (12) ◽  
pp. 1560-1568
Author(s):  
Michele Di Stefano ◽  
Ennio Pucci ◽  
Emanuela Miceli ◽  
Elisabetta Pagani ◽  
Natascia Brondino ◽  
...  
Keyword(s):  
Functional Dyspepsia ◽  
Distress Syndrome ◽  
Epigastric Pain ◽  
Pain Syndrome ◽  
Gastric Accommodation ◽  
Postprandial Distress Syndrome ◽  
Epigastric Pain Syndrome ◽  
Gastric Emptying Time ◽  
Early Satiation ◽  
Severe Migraine

Background Migraine is a condition frequently associated with gastrointestinal disorders. Previous reports have shown the relationship between irritable bowel syndrome and migraine, but no data are yet available in patients with functional dyspepsia. We therefore evaluated whether alteration of gastric sensorimotor activity may be related to migraine. Methods Sixty patients affected by functional dyspepsia, 38 with postprandial distress syndrome and 22 with epigastric pain syndrome were enrolled in a cohort study. Presence and severity of dyspeptic symptoms, migraine presence and severity, gastric sensitivity thresholds during fasting and postprandial period, gastric accommodation and gastric emptying time were evaluated. Results In epigastric pain syndrome, 12/22 (54%) patients suffered from migraine and this condition was never correlated with meal ingestion. In postprandial distress syndrome patients, 29/38 (76%) suffered from migraine, in 26/29 (89%) its onset was considered as meal-related, and migraine severity was significantly correlated with postprandial modification of the gastric discomfort threshold (r = −0.73; p < 0.001). In patients with postprandial distress syndrome, in the subgroup with moderate to severe migraine, the severity of fullness and early satiation was significantly higher than in patients with mild or absent migraine. In patients with moderate to severe migraine, gastric accommodation, sensitivity thresholds and gastric emptying time were similar to patients with mild or no migraine. Conclusions In patients with functional dyspepsia and postprandial symptoms, migraine is a very frequent comorbidity. On clinical grounds, it is associated with an increased severity of fullness and early satiation and, on pathophysiological grounds, it seems correlated with postprandial hypersensitivity.

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