scholarly journals Impaired Colonic Contractility and Intestinal Permeability in Symptomatic Uncomplicated Diverticular Disease

2021 ◽  
Author(s):  
Annamaria Altomare ◽  
Manuele Gori ◽  
Silvia Cocca ◽  
Simone Carotti ◽  
Maria Francesconi ◽  
...  
Keyword(s):  
Diverticular Disease ◽  
Intestinal Permeability ◽  
Uncomplicated Diverticular Disease

Transient Lactose Malabsorption in Patients Affected by Symptomatic Uncomplicated Diverticular Disease of the Colon

2006 ◽  
Vol 51 (3) ◽  
pp. 461-465 ◽  
Author(s):  
Antonio Tursi ◽  
Giovanni Brandimarte ◽  
Gian Marco Giorgetti ◽  
Walter Elisei
Keyword(s):  
Diverticular Disease ◽  
Lactose Malabsorption ◽  
Uncomplicated Diverticular Disease

OC.07.3 RISKS FACTORS IN SYMPTOMATIC UNCOMPLICATED DIVERTICULAR DISEASE

2021 ◽  
Vol 53 ◽  
pp. S120
Author(s):  
A. Gioia ◽  
G. Schirò ◽  
C. Corrado ◽  
N. Rollo ◽  
C. Severi
Keyword(s):  
Diverticular Disease ◽  
Risks Factors ◽  
Uncomplicated Diverticular Disease

scholarly journals Diverticular fistulation is associated with nicorandil usage

2010 ◽  
Vol 92 (6) ◽  
pp. 463-465 ◽  
Author(s):  
James McDaid ◽  
Claire Reichl ◽  
Ihsan Hamzah ◽  
Samantha Fitter ◽  
Laura Harbach ◽  
...  
Keyword(s):  
Diverticular Disease ◽  
Fistula Formation ◽  
Control Group ◽  
Number Of Patients ◽  
Significant Difference ◽  
Patient Groups ◽  
The Mean ◽  
Uncomplicated Diverticular Disease ◽  
And Control ◽  
Control Study

INTRODUCTION We observed that a number of patients presenting to our clinic with diverticular fistulation were taking nicorandil for angna. Recognised side effects of nicorandil include gastrointestinal and genital ulceration. The aim of our study was to determine whether nicorandil is an aetiological agent in diverticular fistulation. PATIENTS AND METHODS We conducted a case-control study of patients with diverticular disease related enteric fistulae. Two patient groups were identified: a study group of patients with diverticular fistulae, and a control group with uncomplicated diverticular disease. The proportion of patients who had ever used nicorandil was compared between the two groups. RESULTS A total of 153 case notes were analysed, 69 patients with fistulae and 84 control patients with uncomplicated diverticular disease. Female to male ratio in both groups was 2:1. The mean age was 71 years in the fistula group and 69 years in the control diverticular disease group (P = ns). Of those with colonic fistulae, 16% were taking nicorandil compared with 2% of the control group (odds ratio 7.8; 95% confidence interval 1.5–39.1; P = 0.008). There was no significant difference in rates of ischaemic heart disease between fistula and control groups. CONCLUSIONS Nicorandil is associated with fistula formation in diverticular disease.

scholarly journals Quality of life after laparoscopic surgery of uncomplicated diverticular disease

2018 ◽  
Vol 3 ◽  
pp. 55-55
Author(s):  
Kirien Kjossev ◽  
Roberto Cirocchi ◽  
Georgi Popivanov ◽  
Ventsislav Mutafchiyski
Keyword(s):  
Quality Of Life ◽  
Laparoscopic Surgery ◽  
Diverticular Disease ◽  
Uncomplicated Diverticular Disease

scholarly journals Role of Inflammation in the Pathogenesis of Diverticular Disease

2019 ◽  
Vol 2019 ◽  
pp. 1-7 ◽  
Author(s):  
Antonio Tursi ◽  
Walter Elisei
Keyword(s):  
Diverticular Disease ◽  
Acute Diverticulitis ◽  
Human Colon ◽  
Recurrent Abdominal Pain ◽  
Preliminary Evidence ◽  
Low Grade ◽  
Symptom Persistence ◽  
Uncomplicated Diverticular Disease ◽  
Low Grade Inflammation

Diverticulosis of the colon is the most common condition in Western societies and it is the most common anatomic alteration of the human colon. Recurrent abdominal pain is experienced by about 20% of patients with diverticulosis, but the pathophysiologic mechanisms of its occurrence are not completely understood. In the last years, several fine papers have showed clearly the role of low-grade inflammation both in the occurrence of symptoms in people having diverticulosis, both in symptom persistence following acute diverticulitis, even if the evidence available is not so strong. We do not know yet what the trigger of this low-grade inflammation occurrence is. However, some preliminary evidence found colonic dysbiosis linked to low-grade inflammation and therefore to symptom occurrence in those patients. The aim of this paper is to summarize current evidences about the role of inflammation in symptom occurrence in symptomatic uncomplicated diverticular disease and in symptom persistence after an episode of acute diverticulitis.

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