scholarly journals Assessment of Pyloric Sphincter Physiology Using Functional Luminal Imaging Probe in Healthy Volunteers

2020 ◽  
Vol 26 (3) ◽  
pp. 391-396
Author(s):  
Nitin Jagtap ◽  
Rakesh Kalapala ◽  
D Nageshwar Reddy
Keyword(s):  
Healthy Volunteers ◽  
Pyloric Sphincter ◽  
Imaging Probe ◽  
Functional Luminal Imaging Probe

scholarly journals Normal Values of Esophageal Distensibility and Distension-Induced Contractility Measured by Functional Luminal Imaging Probe Panometry

2019 ◽  
Vol 17 (4) ◽  
pp. 674-681.e1 ◽  
Author(s):  
Dustin A. Carlson ◽  
Wenjun Kou ◽  
Zhiyue Lin ◽  
Monique Hinchcliff ◽  
Anjali Thakrar ◽  
...  
Keyword(s):  
Normal Values ◽  
Imaging Probe ◽  
Functional Luminal Imaging Probe

scholarly journals Mechanisms of repetitive retrograde contractions in response to sustained esophageal distension: a study evaluating patients with postfundoplication dysphagia

2018 ◽  
Vol 314 (3) ◽  
pp. G334-G340 ◽  
Author(s):  
Dustin A. Carlson ◽  
Peter J. Kahrilas ◽  
Katherine Ritter ◽  
Zhiyue Lin ◽  
John E. Pandolfino
Keyword(s):  
Nissen Fundoplication ◽  
Motor Disorder ◽  
Outflow Obstruction ◽  
Imaging Probe ◽  
High Resolution Manometry ◽  
Type Iii ◽  
Common Response ◽  
Barium Esophagram ◽  
Functional Luminal Imaging Probe ◽  
Type Iii Achalasia

Repetitive retrograde contractions (RRCs) in response to sustained esophageal distension are a distinct contractility pattern observed with functional luminal imaging probe (FLIP) panometry that are common in type III (spastic) achalasia. RRCs are hypothesized to be indicative of either impaired inhibitory innervation or esophageal outflow obstruction. We aimed to apply FLIP panometry to patients with postfundoplication dysphagia (a model of esophageal obstruction) to explore mechanisms behind RRCs. Adult patients with dysphagia after Nissen fundoplication ( n = 32) or type III achalasia ( n = 25) were evaluated with high-resolution manometry (HRM) and upper endoscopy with FLIP. HRM studies were assessed for outflow obstruction and spastic features: premature contractility, hypercontractility, and impaired deglutitive inhibition during multiple-rapid swallows. FLIP studies were analyzed to determine the esophagogastric junction (EGJ)-distensibility index and contractility pattern, including RRCs. Barium esophagram was evaluated when available. RRCs were present in 8/32 (25%) fundoplication and 19/25 (76%) achalasia patients ( P < 0.001). EGJ outflow obstruction was detected in 21 (67%) fundoplication patients by HRM, FLIP, or esophagram [6 (29%) had RRCs]. On HRM, none of the fundoplication patients had premature contractility, whereas 3/4 with defective inhibition on multiple-rapid swallows and 2/4 with hypercontractility had RRCs. Regression analysis demonstrated HRM with spastic features, but not esophageal outflow obstruction, as a predictor for RRCs. RRCs in response to sustained esophageal distension appear to be a manifestation of spastic esophageal motility. Although future study to further clarify the significance of RRCs is needed, RRCs on FLIP panometry should prompt evaluation for a major motor disorder. NEW & NOTEWORTHY Repetitive retrograde contractions (RRCs) are a common response to sustained esophageal distension among spastic achalasia patients when evaluated with the functional luminal imaging probe. We evaluated patients with postfundoplication dysphagia, i.e., patients with suspected mechanical obstruction, and found that RRCs occasionally occurred among postfundoplication patients, but often in association with manometric features of esophageal neuromuscular imbalance. Thus, RRCs appear to be a manifestation of spastic esophageal dysmotility, likely from neural imbalance resulting in excess excitation.

scholarly journals Functional Luminal Imaging Probe Panometry Identifies Achalasia-Type Esophagogastric Junction Outflow Obstruction

2020 ◽  
Vol 18 (10) ◽  
pp. 2209-2217 ◽  
Author(s):  
Joseph R. Triggs ◽  
Dustin A. Carlson ◽  
Claire Beveridge ◽  
Wenjun Kou ◽  
Peter J. Kahrilas ◽  
...  
Keyword(s):  
Esophagogastric Junction ◽  
Outflow Obstruction ◽  
Imaging Probe ◽  
Functional Luminal Imaging Probe

T1972 Mechanics of the Esophagogastric Junction in Postfundoplication Patients As Assessed By Functional Luminal Imaging Probe

2008 ◽  
Vol 134 (4) ◽  
pp. A-591 ◽  
Author(s):  
Monika A. Kwiatek ◽  
William J. Bulsiewicz ◽  
Sudip K. Ghosh ◽  
Barry P. McMahon ◽  
Hans Gregersen ◽  
...  
Keyword(s):  
Esophagogastric Junction ◽  
Imaging Probe ◽  
Functional Luminal Imaging Probe

Su1770 MEASUREMENT OF THE PYLORIC SPHINCTER USING THE FUNCTIONAL LUMEN IMAGING PROBE (FLIP) IS HIGHLY DEPENDENT ON FLIP BALLOON POSITION

2020 ◽  
Vol 158 (6) ◽  
pp. S-641
Author(s):  
Brandon Yim ◽  
Robert M. Siwiec ◽  
Mohammad A. Al-Haddad ◽  
Thomas V. Nowak ◽  
John M. Wo
Keyword(s):  
Pyloric Sphincter ◽  
Imaging Probe ◽  
Functional Lumen Imaging Probe

Prediction of Esophageal Retention: A Study Comparing High-Resolution Manometry and Functional Luminal Imaging Probe Panometry

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Dustin A. Carlson ◽  
Alexandra J. Baumann ◽  
Jacqueline E. Prescott ◽  
Jacob M. Schauer ◽  
Amanda Krause ◽  
...  
Keyword(s):  
High Resolution ◽  
Imaging Probe ◽  
High Resolution Manometry ◽  
Functional Luminal Imaging Probe
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