scholarly journals Can Nocturnal Acid-breakthrough Be Reduced by Long-acting Proton Pump Inhibitors?

2017 ◽  
Vol 23 (2) ◽  
pp. 145-148 ◽  
Author(s):  
Hye Kyung Jeon ◽  
Gwang Ha Kim
2020 ◽  
Vol 9 (11) ◽  
pp. 3728
Author(s):  
Jordan Guillot ◽  
Sandy Maumus-Robert ◽  
Alexandre Marceron ◽  
Pernelle Noize ◽  
Antoine Pariente ◽  
...  

We aimed to describe the burden represented by potentially inappropriate medications (PIMs) in chronic polypharmacy in France. We conducted a nationwide cross-sectional study using data from the French National Insurance databases. The study period was from 1 January 2016 to 31 December 2016. Chronic drug use was defined as uninterrupted daily use lasting ≥6 months. Chronic polypharmacy was defined as the chronic use of ≥5 medications, and chronic hyperpolypharmacy as the chronic use of ≥10 medications. For individuals aged ≥65 (older adults), PIMs were defined according to the Beers and Laroche lists, and for individuals aged 45–64 years (middle-aged) PIMs were defined according to the PROMPT (Prescribing Optimally in Middle-aged People’s Treatments) list. Among individuals with chronic polypharmacy, 4009 (46.2%) middle-aged and 18,036 (64.8%) older adults had at least one chronic PIM. Among individuals with chronic hyperpolypharmacy, these figures were, respectively, 570 (75.0%) and 2544 (88.7%). The most frequent chronic PIM were proton pump inhibitors (43.4% of older adults with chronic polypharmacy), short-acting benzodiazepines (older adults: 13.7%; middle-aged: 16.1%), hypnotics (6.1%; 7.4%), and long-acting sulfonylureas (3.9%; 12.3%). The burden of chronic PIM appeared to be very high in our study, concerning almost half of middle-aged adults and two-thirds of older adults with chronic polypharmacy. Deprescribing interventions in polypharmacy should primarily target proton pump inhibitors and hypnotics.


2006 ◽  
Vol 42 (2) ◽  
pp. 160-165 ◽  
Author(s):  
Marian D Pfefferkorn ◽  
Joseph M Croffie ◽  
Sandeep K Gupta ◽  
Jean P Molleston ◽  
George J Eckert ◽  
...  

2001 ◽  
Vol 120 (5) ◽  
pp. A655-A656
Author(s):  
H NAKAMURA ◽  
H YOSHIYAMA ◽  
H YANAI ◽  
M SHIRAL ◽  
T NAKAZAWA ◽  
...  

2015 ◽  
Vol 21 ◽  
pp. 139
Author(s):  
Muhammad Mahmood ◽  
Andrew Kinch ◽  
Woodall Brittany ◽  
Ayman Elkadry

2018 ◽  
Vol 24 ◽  
pp. 157-158
Author(s):  
Franco Vallejo Garcia ◽  
Melissa Sum

2009 ◽  
Vol 104 (4) ◽  
pp. 1072-1072
Author(s):  
Joel J Heidelbaugh ◽  
Kathleen L Goldberg ◽  
John M Inadomi

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