scholarly journals Dust formation history of galaxies: A critical role of metallicity dust mass growth by accreting materials in the interstellar medium

2013 ◽  
Vol 65 (3) ◽  
pp. 213-222 ◽  
Author(s):  
Ryosuke S. Asano ◽  
Tsutomu T. Takeuchi ◽  
Hiroyuki Hirashita ◽  
Akio K. Inoue
Keyword(s):  
Interstellar Medium ◽  
Critical Role ◽  
Dust Formation ◽  
Mass Growth ◽  
Formation History ◽  
Dust Mass ◽  
History Of

Friends of Rose Canyon

2018 ◽  
Vol 95 (3) ◽  
pp. 2-20 ◽  
Author(s):  
Andrew Wiese
Keyword(s):  
Open Space ◽  
Critical Role ◽  
First Century ◽  
Grassroots Politics ◽  
History Of ◽  
University City ◽  
Participant Observer ◽  
The Rose

Place-based activism has played a critical role in the history of urban and environmental politics in California. This article explores the continuing significance of environmental place making to grassroots politics through a case study of Friends of Rose Canyon, an environmental group in San Diego. Based in the fast-growing University City neighborhood, Friends of Rose Canyon waged a long, successful campaign between 2002 and 2018 to prevent construction of a bridge in the Rose Canyon Open Space Park in their community. Using historical and participant observer methodologies, this study reveals how twenty-first-century California urbanites claimed and created meaningful local places and mobilized effective politics around them. It illuminates the critical role of individual activists; suggests practical, replicable strategies for community mobilization; and demonstrates the significant impact of local activism at the urban and metropolitan scales.

scholarly journals CHEK2∗1100delC Mutation and Risk of Prostate Cancer

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Victoria Hale ◽  
Maren Weischer ◽  
Jong Y. Park
Keyword(s):  
Prostate Cancer ◽  
Current Knowledge ◽  
Prostate Cancer Screening ◽  
Critical Role ◽  
Prostate Cancer Risk ◽  
Conclusive Evidence ◽  
Increased Risk ◽  
History Of ◽  
Cancer Studies

Although the causes of prostate cancer are largely unknown, previous studies support the role of genetic factors in the development of prostate cancer.CHEK2plays a critical role in DNA replication by responding to double-stranded breaks. In this review, we provide an overview of the current knowledge of the role of a genetic variant, 1100delC, ofCHEK2on prostate cancer risk and discuss the implication for potential translation of this knowledge into clinical practice. Currently, twelve articles that discussedCHEK2∗1100delC and its association with prostate cancer were identified. Of the twelve prostate cancer studies, five studies had independent data to draw conclusive evidence from. The pooled results of OR and 95% CI were 1.98 (1.23–3.18) for unselected cases and 3.39 (1.78–6.47) for familial cases, indicating thatCHEK2∗1100delC mutation is associated with increased risk of prostate cancer. Screening for CHEK2∗1100delC should be considered in men with a familial history of prostate cancer.

scholarly journals Winds of metal-poor OB stars: Updates from HST-COS UV spectroscopy

2014 ◽  
Vol 9 (S307) ◽  
pp. 41-46
Author(s):  
M. García ◽  
A. Herrero ◽  
F. Najarro ◽  
D. J. Lennon ◽  
M. A. Urbaneja
Keyword(s):  
Massive Stars ◽  
Uv Spectroscopy ◽  
Star Formation History ◽  
First Stars ◽  
Abundance Pattern ◽  
Ob Stars ◽  
Formation History ◽  
History Of ◽  
Strong Winds

AbstractIn the race to break the SMC frontier and reach metallicity conditions closer to the First Stars the information from UV spectroscopy is usually overlooked. New HST-COS observations of OB stars in the metal-poor galaxy IC1613, with oxygen content ~1/10 solar, have proved the important role of UV spectroscopy to characterize blue massive stars and their winds. The terminal velocities (υ∞) and abundances derived from the dataset have shed new light on the problem of metal-poor massive stars with strong winds. Furthermore, our results question the υ∞-υesc and υ∞-Z scaling relations whose use in optical-only studies may introduce large uncertainties in the derived mass loss rates and wind-momenta. Finally, our results indicate that the detailed abundance pattern of each star may have a non-negligible impact on its wind properties, and scaling these as a function of one single metallicity parameter is probably too coarse an approximation. Considering, for instance, that the [α/Fe] ratio evolves with the star formation history of each galaxy, we may be in need of updating all our wind recipes.

The Carnegie Uaxactun Project and the Development of Maya Archaeology

1990 ◽  
Vol 1 (2) ◽  
pp. 257-276 ◽  
Author(s):  
Stephen L. Black
Keyword(s):  
Large Scale ◽  
Critical Role ◽  
Carnegie Institution ◽  
Field Methods ◽  
Maya Archaeology ◽  
History Of ◽  
Maya Area

AbstractThe Carnegie Institution of Washington's 1924–1937. Uaxactun Project, one of the first large-scale excavations in the Maya area, established the role of dirt archaeology in Maya studies. The archaeologists who worked on this pioneering project developed many field methods and approaches that remain in use today. A review of the project and of the careers of its participants shows the critical role the Carnegie Uaxactun Project has played in the history of Maya archaeology.

scholarly journals GPIHBP1 C89F Neomutation and Hydrophobic C-Terminal Domain G175R Mutation in Two Pedigrees with Severe Hyperchylomicronemia

2011 ◽  
Vol 96 (10) ◽  
pp. E1675-E1679 ◽  
Author(s):  
Sybil Charrière ◽  
Noël Peretti ◽  
Sophie Bernard ◽  
Mathilde Di Filippo ◽  
Agnès Sassolas ◽  
...  
Keyword(s):  
Critical Role ◽  
Phenotypic Expression ◽  
Missense Mutations ◽  
Terminal Domain ◽  
Apoa5 Gene ◽  
Key Enzyme ◽  
History Of ◽  
Functional Consequences ◽  
Signal Peptide Polymorphism

Abstract Context: GPIHBP1 is a new endothelial binding site for lipoprotein lipase (LPL), the key enzyme for intravascular lipolysis of triglyceride-rich lipoproteins (TGRL). We have identified two new missense mutations of the GPIHBP1 gene, C89F and G175R, by systematic sequencing in a cohort of 376 hyperchylomicronemic patients without mutations on the LPL, APOC2, or APOA5 gene. Objective: Phenotypic expression and functional consequences of these two mutations were studied. Design: We performed clinical and genotypic studies of probands and their families. GPIHBP1 functional alterations were studied in CHO pgsA-745 transfected cells. Results: Probands are an adult with a homozygous G175R mutation and a child with a hemizygous C89F neomutation and a deletion of the second allele. C89F mutation was associated with a C14F signal peptide polymorphism on the same haplotype. Both patients had resistant hyperchylomicronemia, low LPL activity, and history of acute pancreatitis. In CHO pgsA-745 cells, both G175R and C14F variants reduce the expression of GPIHBP1 at the cell surface. C89F mutation is responsible for a drastic LPL-binding defect to GPIHBP1. C14F may further potentiate C89F effect. Conclusions: The emergence of hyperchylomicronemia in the generation after a neomutation further establishes a critical role for GPIHBP1 in TGRL physiopathology in humans. Our results highlight the crucial role of C65-C89 disulfide bond in LPL binding by GPIHBP1 Ly6 domain. Furthermore, we first report a mutation of the hydrophobic C-terminal domain that impairs GPIHBP1 membrane targeting.

scholarly journals HUBBLE SPACE TELESCOPEGRISM SPECTROSCOPY OF EXTREME STARBURSTS ACROSS COSMIC TIME: THE ROLE OF DWARF GALAXIES IN THE STAR FORMATION HISTORY OF THE UNIVERSE

2014 ◽  
Vol 789 (2) ◽  
pp. 96 ◽  
Author(s):  
Hakim Atek ◽  
Jean-Paul Kneib ◽  
Camilla Pacifici ◽  
Matthew Malkan ◽  
Stephane Charlot ◽  
...  
Keyword(s):  
Star Formation ◽  
Dwarf Galaxies ◽  
Cosmic Time ◽  
Star Formation History ◽  
Formation History ◽  
History Of ◽  
The Universe

scholarly journals CULTUROLOGICAL ORIENTATORS OF MODERN UKRAINIAN CINEMA CRITICS

2020 ◽  
pp. 18-22
Author(s):  
T. G. Kokhan
Keyword(s):  
Creative Process ◽  
Cultural Analysis ◽  
Reference Points ◽  
Cultural Traditions ◽  
Cinema Studies ◽  
Formation History ◽  
History Of ◽  
Personalized Approach ◽  
Ethics And Psychology

The article analyses the position of Ukrainian scientists, represented in their works during the first two decades of the XXI century, when the influence of the basis of the cultural analyses on the development of cinema critics has become appreciable. The accent has been made on new approaches both to the history of Ukrainian cinema in trying to understand personalized approach prevails and to the estimation of subject direction of the films shoot on the boundary of the XX – XXI centuries. It is underlined that film expert's attention was concentrated on the further improvement of notion-categorical apparatus which provides investigations in film critics. It is shown that film science outlines some human problems which having historical cultural traditions, can appear as aesthetical-artistic reference points in creative process. It is declared that the important aspect of the article is dedicated to the fixation of the art studies formation history in the process of cinema development. The role of Danish producer Urban Gad, the author of the book "Cinema, its means and aims" is marked. It is indicated that while constantly shooting films U.Gad summarized his own experience of work in the cinema making in the first European investigation in the cinema studies. It is underlined that taking into consideration the dynamics of cinematograph's development, using of historical and cultural achievements of the past as reference points for modern cinema theory demands caution and correctness. In the context of this thesis systematization and analysis of works of Ukrainian film critics on the activities of national cinematograph's development are presented both actual and expediency. It is shown that using in the cinema study fundamental principles of cultural analysis in particular cross-scientific personalization a composed element of biographic method – to correlate cinema analysis with material of such human sciences as aesthetics, ethics and psychology. It is noticed that taking into consideration collective character of the creation in cinematograph the principle of personalization objectively appraises the contribution of each representative of the cinematic group within the creative process.

scholarly journals The Star Formation History of Eridanus II: On the Role of Supernova Feedback in the Quenching of Ultrafaint Dwarf Galaxies*

2021 ◽  
Vol 909 (2) ◽  
pp. 192 ◽  
Author(s):  
C. Gallart ◽  
M. Monelli ◽  
T. Ruiz-Lara ◽  
A. Calamida ◽  
S. Cassisi ◽  
...  
Keyword(s):  
Star Formation ◽  
Dwarf Galaxies ◽  
Star Formation History ◽  
Formation History ◽  
History Of ◽  
Supernova Feedback

A History of Bodies

2018 ◽  
pp. 237-250
Author(s):  
Annette Rodríguez
Keyword(s):  
Twentieth Century ◽  
Mexican American ◽  
Critical Role ◽  
Historical Analysis ◽  
Mexican American Women ◽  
Pedagogical Choices ◽  
History Of ◽  
Definition Of ◽  
The Continuum

This chapter explores the development of pedagogical choices and historical practice via familial and professional mentorship. Rodríguez argues for the critical role of mentorship for the development of women in the historical profession. Naming her work “a history of the gaps,” she discusses widening the definition of historical actors as well as subjects of historical analysis. As an example, the chapter points to the continuum of women acting against racist violence, documenting, analyzing, and historicizing racist violence—against previously masculinist narratives. Demonstrating a “history of the gaps,” Rodríguez’s chapter concludes with the testimonies of Mexican and Mexican American women whose X marks confirmed anti-Mexican murders at the turn of the twentieth century.

Building the Black Arts Movement

2019 ◽  
Author(s):  
Jonathan Fenderson
Keyword(s):  
Critical Role ◽  
Culture Wars ◽  
Black Arts Movement ◽  
Institution Building ◽  
Black Arts ◽  
Editorial Work ◽  
History Of ◽  
The 1960S ◽  
Creative Artists

This book is the first to document and analyze Hoyt Fuller’s profound influence on the Black Arts movement. Using historical snapshots of Fuller’s life and activism as a means to rethink the period, Building the Black Arts Movement provides a fresh take on the general trajectory of African American literary (and cultural) studies as the field developed over the course of two explosive decades in the mid-twentieth century. The book argues that the Black Arts movement can be understood as a pivotal and volatile moment in the long history of America’s culture wars. Moreover, by shifting our focus from creative artists and repositioning Fuller at the center of the movement--as one of its most underappreciated architects--the book grants new insights into the critical role of editorial work, the international dimensions of the movement, the complexities of sexuality, and the challenges of Black institution building during the 1960s and ’70s.

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