scholarly journals A retrospective analysis of cytogenetic alterations in patients with newly diagnosed multiple myeloma: a single center study in Korea

2016 ◽  
Vol 51 (2) ◽  
pp. 122 ◽  
Author(s):  
Shuhua Li ◽  
Hyeon-Ho Lim ◽  
Kwang-Sook Woo ◽  
Sung-Hyun Kim ◽  
Jin-Yeong Han
Keyword(s):  
Multiple Myeloma ◽  
Retrospective Analysis ◽  
Newly Diagnosed ◽  
Single Center ◽  
Single Center Study ◽  
Center Study

scholarly journals Pulsed Radiofrequency Application on Femoral and Obturator Nerves for Hip Joint Pain: Retrospective Analysis with 12-Month Follow-up Results

2018 ◽  
Vol 1 (21;1) ◽  
pp. 407-414 ◽  
Author(s):  
Andrea Tinnirello
Keyword(s):  
Retrospective Analysis ◽  
Hip Joint ◽  
Joint Pain ◽  
Pulsed Radiofrequency ◽  
Single Center ◽  
Medium Term ◽  
Post Procedure ◽  
Single Center Study ◽  
Center Study

Background: Osteoarthritis of the hip joint is a common cause of pain and disability. Patients not responding to conservative management often cannot undergo joint replacement due to the presence of multiple comorbidities, while some other patients prefer to postpone surgery as long as possible. Radiofrequency denervation of articular branches of the femoral and obturator nerves, which supply innervation of the joint, is a novel technique to reduce hip joint pain. Previous studies reported positive results after application of continuous radiofrequency to the target nerves; however, this approach carries the potential risk of neuritis and neuroma formation. Pulsed radiofrequency (PRF) is a safer alternative to continuous radiofrequency not creating necrosis but a complex neuromodulatory effect on target nerves. There is no published evidence of PRF efficacy after 3 month follow-up. Objectives: This single-center study objective was to evaluate the short and medium term effectiveness of PRF on the femoral articular branches and obturator nerves in patients with chronic hip pain. Study Design: Retrospective single-center study. Setting: Italian National Health Service Public Hospital. Methods: Retrospective analysis of 14 patients treated with PRF for severe hip joint pain (mean numeric rating scale (NRS) 7.7 ± 1.2 mean Oxford Hip Score (OHS) 20 ± 8.4). Mean pain and disability scores were evaluated with NRS and OHS respectively at 1, 3, 6, and 12-month follow-up. All patients were treated with pulsed radiofrequency applied under fluoroscopy on the articular branches of the femoral and obturator nerves for 300 seconds each. Results: Eight patients out of 14 (57%) reported an NRS reduction > 50% at 1 month post procedure. Overall, both pain and disability scores were significantly (P < 0.01) lower at all follow-up until 6 months, mean NRS at 1, 3, and 6 months was 3.6 ± 3; 4.1 ± 3.3; 4.8 ± 2.9 while OHS was 37.6 ± 17.7; 35.8 ± 17.7; 35.8 ± 14 respectively. At 12 months, NRS was 5.8 ± 2.4 while OHS 23.3 ± 12.7, it must be pointed out that even if both scores are significantly (P < 0.01) lower than basal, only 3 patients out of 14 (21%) maintained a NRS reduction > 50% from basal at 12 months post procedure. We reported 2 femoral artery punctures without any significant complication. Limitations: Retrospective study, small sample size. Conclusions: Pulsed radiofrequency is a safe and effective modality to treat hip joint pain in the short and medium term. Definition of positive outcome predictors is required to reserve radiofrequency treatment only for those patients who can benefit from this procedure. Key words: Hip joint pain, pulsed radiofrequency, obturator nerve, femoral nerve, interventional pain management, radiofrequency

scholarly journals Retrospective analysis of prescriptions in the management of lepra reactions: Results of a single center study from tertiary hospital in Maharashtra

2017 ◽  
Vol 10 (5) ◽  
pp. 191
Author(s):  
Madhuri Kulkarni ◽  
Anant Patil ◽  
Siddharth Aathawale
Keyword(s):  
Retrospective Study ◽  
Antimicrobial Agent ◽  
Retrospective Analysis ◽  
Tertiary Hospital ◽  
Single Center ◽  
Single Center Study ◽  
Multibacillary Leprosy ◽  
Center Study

Objective: To examine pattern of lepra reaction andmedicines used in the treatment of lepra reactions in a tertiary hospital. Material methods: In this retrospective study, prescriptions of patients treated for the lepra reactions were reviewed to find out prevalence of type 1 and type 2 reactions and medicines used in the treatment of lepra reactions. Results:A total of66 patients (male 59.1%; female 40.9%) with mean age of 36.6 (+13.1) years were included in the study. Multibacillary leprosy was present in 93.7% patients.  A total of 39 (60%) patients had type 2 reaction whereas 26 (40%) had type 1 reaction. Mean number of medicines per patients was 7.5. Prednisolone was used in 62 (93.9%) patients with mean duration of 33.32 (+33.2) days whereas chloroquine was used in 52 (78.8%) patients for 36.6 (+27.9) days. Thalidomide was used in 25 (37.9%) patients. Analgesic and anti-inflammatory and anti-acidity drugs were used in 63 (95.4%) patients each whereas paracetamol was given to 41 (62.1%) patients. Antihistamine, antimicrobial agent and vitamins were given to 27 (40.9%), 27 (40.9%) and 35 (53.0%) patients respectively. Conclusion:Lepra 2 reaction is more common than lepra 1 reaction.  Prednisolone and chloroquine are the two most commonly used medicines in the treatment of lepra reaction. Similarly, thalidomide, older drug has emerged as common treatment for lepra reaction.

A retrospective analysis of obstetric patients with idiopathic thrombocytopenic purpura: a single center study

2010 ◽  
Vol 92 (3) ◽  
pp. 463-467 ◽  
Author(s):  
Atsuko Fujita ◽  
Rika Sakai ◽  
Shiro Matsuura ◽  
Wataru Yamamoto ◽  
Rika Ohshima ◽  
...  
Keyword(s):  
Retrospective Analysis ◽  
Idiopathic Thrombocytopenic Purpura ◽  
Single Center ◽  
Thrombocytopenic Purpura ◽  
Single Center Study ◽  
Center Study

scholarly journals Retrospective analysis of the surgical management of spontaneous supratentorial intracerebral hemorrhage: A single-center study

2021 ◽  
Vol 2021 (3) ◽  
Author(s):  
Ahmed Shaaban ◽  
Maher Saqqur ◽  
Ahmed Saleh ◽  
Alaaeldin Ahmed ◽  
Hussain Hussain ◽  
...  
Keyword(s):  
Intracerebral Hemorrhage ◽  
Retrospective Analysis ◽  
Surgical Management ◽  
Single Center ◽  
Single Center Study ◽  
Center Study
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