Statistical Inference of Semiparametric Varying Coefficients Using Mixed Effects Model

2013 ◽  
Vol 42 (1) ◽  
pp. 1-10
Author(s):  
Kenichi Satoh ◽  
Tetsuji Tonda
Author(s):  
Juan David Ospina ◽  
Oscar Acosta ◽  
Gaël Dréan ◽  
Guillaume Cazoulat ◽  
Antoine Simon ◽  
...  

2021 ◽  
Vol 11 ◽  
Author(s):  
Lukasz Wiklendt ◽  
Marcello Costa ◽  
Mark S. Scott ◽  
Simon J. H. Brookes ◽  
Phil G. Dinning

Manual analysis of human high-resolution colonic manometry data is time consuming, non-standardized and subject to laboratory bias. In this article we present a technique for spectral analysis and statistical inference of quasiperiodic spatiotemporal signals recorded during colonic manometry procedures. Spectral analysis is achieved by computing the continuous wavelet transform and cross-wavelet transform of these signals. Statistical inference is achieved by modeling the resulting time-averaged amplitudes in the frequency and frequency-phase domains as Gaussian processes over a regular grid, under the influence of categorical and numerical predictors specified by the experimental design as a functional mixed-effects model. Parameters of the model are inferred with Hamiltonian Monte Carlo. Using this method, we re-analyzed our previously published colonic manometry data, comparing healthy controls and patients with slow transit constipation. The output from our automated method, supports and adds to our previous manual analysis. To obtain these results took less than two days. In comparison the manual analysis took 5 weeks. The proposed mixed-effects model approach described here can also be used to gain an appreciation of cyclical activity in individual subjects during control periods and in response to any form of intervention.


2020 ◽  
Vol 39 (15) ◽  
pp. 2051-2066 ◽  
Author(s):  
Rui Wang ◽  
Ante Bing ◽  
Cathy Wang ◽  
Yuchen Hu ◽  
Ronald J. Bosch ◽  
...  

2020 ◽  
Vol 6 (1) ◽  
pp. 132-153
Author(s):  
Brandon M. A. Rogers

AbstractThe current study examines /s/ variation in the southern-central city of Concepción, Chile and its relation to a variety of linguistic and social factors. A proportional-odds mixed effects model, with the random factor of “speaker”, was used to treat the categorically coded data on a continuum of acoustical variation ([s] > [h] > ∅). The results presented show that contrary to the previous assertions, heavy sibilant reduction, especially elision, in Concepción, Chile is the rule, rather than the exception, to the extent that it is no longer a marker of certain social demographics as has been reported previously. Furthermore, based on the trends reported, it is likely that this has been the case for several decades. Finally, the overall observed trends are indicative that the rates of /s/ elision will continue to increase across social demographics and different phonetic and phonological contexts in Concepción, Chile.


Author(s):  
Avinash Chandran ◽  
Derek W. Brown ◽  
Gabriel H. Zieff ◽  
Zachary Y. Kerr ◽  
Daniel Credeur ◽  
...  

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