scholarly journals BMP4-Induced Differentiation of Human Hair Follicle Neural Crest Stem Cells into Precursor Melanocytes from Hair Follicle Bulge

2020 ◽  
Vol 32 (5) ◽  
pp. 409
Author(s):  
Jung-Ho Yoon ◽  
Ho-Jin Kim ◽  
Jung-Hwan Kim ◽  
Tae-Hoon Kim ◽  
Chang-Hoon Seo ◽  
...  
2020 ◽  
Vol 32 (6) ◽  
pp. 539
Author(s):  
Jung-Ho Yoon ◽  
Ho-Jin Kim ◽  
Jung-Hwan Kim ◽  
Tae-Hoon Kim ◽  
Chang-Hoon Seo ◽  
...  

2020 ◽  
Vol 32 (4) ◽  
pp. 289
Author(s):  
Dake Dong ◽  
Shujun Chen ◽  
Cheng Feng ◽  
Huizi Xiong ◽  
Xiaowei Xu

2017 ◽  
Vol 39 (3) ◽  
pp. 171-180 ◽  
Author(s):  
R G Vasyliev ◽  
A E Rodnichenko ◽  
O S Gubar ◽  
A V Zlatska ◽  
I M Gordiienko ◽  
...  

Aim: The purpose of this work was to obtain, multiply and characterize the adult neural crest-derived multipotent stem cells from human hair follicle for their further clinical use. Materials and Methods: Adult neural crest-derived multipotent stem cells were obtained from human hair follicle by explant method and were expanded at large-scale up to a clinically significant number. The resulted cell cultures were examined by flow cytometry and immunocytochemical analysis. Their clonogenic potential, ability to self-renewal and directed multilineage differentiation were also investigated. Results: Cell cultures were obtained from explants of adult human hair follicles. Resulted cells according to morphological, phenotypic and functional criteria satisfied the definition of neural crest-derived multipotent stem cells. They had the phenotype Sox2+Sox10+Nestin+CD73+CD90+CD105+CD140a+CD 140b+CD146+CD166+CD271+CD349+ CD34-CD45-CD56-HLA-DR-, showed high clonogenic potential, ability to self-renewal and directed differentiation into the main derivatives of the neural crest: neurons, Schwann cells, adipocytes and osteoblasts. Conclusion: The possibility of a large-scale expansion of adult neural crest-derived multipotent stem cells up to 40–200·106 cells from minimal number of hair follicles with retention of their phenotype and functional properties are the significant step towards their translation into the clinical practice.


2015 ◽  
Vol 05 (999) ◽  
pp. 1-1
Author(s):  
Abu Bakar Mohd Hilmi ◽  
Mohd Noor Norhayati ◽  
Ahmad Sukari Halim ◽  
Chin Keong Lim ◽  
Zulkifli Mustafa ◽  
...  

2015 ◽  
Vol 26 (7) ◽  
pp. 1314-1327 ◽  
Author(s):  
Seoyoung Son ◽  
Mao-Shih Liang ◽  
Pedro Lei ◽  
Xiaozheng Xue ◽  
Edward P. Furlani ◽  
...  

2012 ◽  
Vol 132 (6) ◽  
pp. 1725-1727 ◽  
Author(s):  
Claire A. Higgins ◽  
Munenari Itoh ◽  
Keita Inoue ◽  
Gavin D. Richardson ◽  
Colin A.B. Jahoda ◽  
...  

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