scholarly journals Variable Sized Cellular Remnants in the Nail Plate of Longitudinal Melanonychia: Evidence of Subungual Melanoma

2015 ◽  
Vol 27 (3) ◽  
pp. 328 ◽  
Author(s):  
Dong-Youn Lee
Keyword(s):  
Nail Plate ◽  
Longitudinal Melanonychia ◽  
Subungual Melanoma

Proximal nail plate destruction in subungual melanoma could be a possible predictor of invasiveness thicker than 1.25 mm

2017 ◽  
Vol 45 (1) ◽  
pp. 83-86 ◽  
Author(s):  
Jun Young Kim ◽  
Moon-Bum Kim ◽  
Byung Cheol Park ◽  
Kee Yang Chung ◽  
You Chan Kim ◽  
...  
Keyword(s):  
Nail Plate ◽  
Subungual Melanoma

scholarly journals Tangential Biopsy Thickness versus Lesion Depth in Longitudinal Melanonychia: A Pilot Study

2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
Nilton Di Chiacchio ◽  
Walter Refkalefsky Loureiro ◽  
Nilceo Schwery Michalany ◽  
Felipe Veiga Kezam Gabriel
Keyword(s):  
Nail Plate ◽  
Histopathological Diagnosis ◽  
Total Thickness ◽  
Thickness Measure ◽  
Histopathologic Diagnosis ◽  
The Matrix ◽  
General Average ◽  
The Mean ◽  
Longitudinal Melanonychia ◽  
Hematoxylin Eosin

Longitudinal melanonychia can be caused by melanocyte activation (hypermelanosis) or proliferation (lentigo, nevus or melanoma). Histopathologic examination is mandatory for suspicious cases of melanomas. Tangential biopsy of the matrix is an elegant technique avoiding nail plate dystrophy, but it was unknown whether the depth of the sample obtained by this method is adequate for histopathologic diagnosis. Twenty-two patients with longitudinal melanonychia striata were submitted to tangential matrix biopsies described by Haneke. The tissue was stained with hematoxylin-eosin and the specimens were measured at 3 distinct points according to the total thickness: largest (A), intermediate (B) and narrowest (C) then divided into 4 groups according to the histopathologic diagnosis (G1: hypermelanosis; G2: lentigos; G3: nevus; G4: melanoma). The lesions were measured using the same method. The mean specimen/lesion thickness measure values for each group was: G1: 0,59/0,10 mm, G2: 0,67/0,08 mm, G3: 0,52/0,05 mm, G4: 0,58/0,10 mm. The general average thickness for all the specimens/lesions was 0,59/0,08 mm. We concluded that the tangential excision, for longitudinal melanonychia, provides an adequate material for histopathological diagnosis.

scholarly journals Dermoscopy of the Month

2018 ◽  
Vol 10 (3) ◽  
pp. 101-104 ◽  
Author(s):  
Andrija Jović ◽  
Danica Tiodorović ◽  
Danijela Popović ◽  
Hristina Kocić ◽  
Zorana Zlatanović ◽  
...  
Keyword(s):  
Nail Plate ◽  
Diagnostic Challenge ◽  
Longitudinal Band ◽  
Malignant Lesions ◽  
Longitudinal Melanonychia

Abstract Melanonychia refers to a brown or black coloration of the nail plate caused by numerous factors. Regarding the arrangement of pigmentation, we can differentiate between total melanonychia, when pigmentation involves the whole nail plate, or transverse or longitudinal melanonychia, when pigmentation involves the nail in a form of transverse or longitudinal band of pigmentation, respectively. Since longitudinal melanonychia can be a sign of numerous benign and malignant lesions, it often poses a diagnostic challenge for a dermatologist. Herein, we report a case of a 13-year-old girl who developed longitudinal melanonychia on multiple nails after receiving a therapy with azithromycin.

scholarly journals Predictor of Subungual Melanoma against Benign Longitudinal Melanonychia: A Retrospective Cohort Study from Korea

2021 ◽  
Vol 33 (2) ◽  
pp. 147
Author(s):  
Su-Hyuk Yim ◽  
In Sun Kwon ◽  
Dongkyun Hong ◽  
Kyung Eun Jung ◽  
Young Lee ◽  
...  
Keyword(s):  
Cohort Study ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Longitudinal Melanonychia ◽  
Subungual Melanoma

Distribution of cellular remnants of melanocytes in the nail plate: Clue to the diagnosis of subungual melanoma

2021 ◽  
Author(s):  
Se Jin Oh ◽  
Jongeun Lee ◽  
Jae Ho Lee ◽  
Jaihee Bae ◽  
Ji‐Hye Park ◽  
...  
Keyword(s):  
Nail Plate ◽  
Subungual Melanoma

LONGITUDINAL MELANONYCHIA: DETECTION AND MANAGEMENT OF NAIL MELANOMA

Hand Surgery ◽  
2013 ◽  
Vol 18 (01) ◽  
pp. 133-139 ◽  
Author(s):  
Kathleen A. Mannava ◽  
Sandeep Mannava ◽  
L. Andrew Koman ◽  
Leslie Robinson-Bostom ◽  
Nathaniel Jellinek
Keyword(s):  
Risk Factors ◽  
Malignant Melanoma ◽  
Mortality Rate ◽  
Delayed Diagnosis ◽  
Nail Plate ◽  
Clinical Approach ◽  
Biopsy Technique ◽  
Longitudinal Melanonychia

Malignant melanoma of the nail confers a higher mortality rate compared to other cutaneous melanomas, which is often attributable to delayed diagnosis. Two-thirds of nail melanomas present as longitudinal melanonychia (LM), longitudinally-oriented brown-black bands of pigment in the nail plate. This article delineates the appropriate clinical approach toward evaluation and management of a patient with longitudinal melanonychia, which includes determining risk factors for melanoma, recognizing scenarios in which biopsy is indicated, selecting the appropriate biopsy technique, and managing a patient in whom the diagnosis of nail melanoma has been made.

scholarly journals Subungual Malignant Melanoma: Difficulty in Early Diagnosis

2013 ◽  
Vol 12 (3) ◽  
pp. 322-325
Author(s):  
Shah Naveed ◽  
Gurpreet Singh ◽  
Hasina Quari
Keyword(s):  
Malignant Melanoma ◽  
Rare Case ◽  
Medical Science ◽  
Nail Plate ◽  
Proximal Interphalangeal Joint ◽  
Interphalangeal Joint ◽  
Cutaneous Lesions ◽  
Early Referral ◽  
Pigmented Lesions ◽  
Subungual Melanoma

A rare case of subungual malignant melanoma in a 43-year-old male, with black dystrophic right thumb nail plate with positive Hutchison sign is presented. Early detection in malignant melanoma is vital for improved treatment outcomes and prognosis. Subungual melanoma presents in a more disguised manner than cutaneous lesions and therefore requires increased vigilance and awareness [1]. Patient underwent disarticulation just distal to the proximal interphalangeal joint. Histopathology confirmed malignant melanoma, and resection free of tumour cells. Our case highlights how any pigmented lesions within the nail bed matrix should raise suspicion and the need for early referral and biopsy.Bangladesh Journal of Medical Science Vol. 12 No. 03 July ’13 Page 322-324 DOI: http://dx.doi.org/10.3329/bjms.v12i3.13200 

scholarly journals Onychophagia Induced Melanonychia, Splinter Hemorrhages, Leukonychia, and Pterygium Inversum Unguis Concurrently

2018 ◽  
Vol 2018 ◽  
pp. 1-3
Author(s):  
Sezin Fıçıcıoğlu ◽  
Selma Korkmaz
Keyword(s):  
Young Adults ◽  
Young Adult ◽  
Nail Plate ◽  
Nail Biting ◽  
Secondary Infections ◽  
Dermatological Disorders ◽  
Children And Young Adults ◽  
Longitudinal Melanonychia ◽  
Biting Behavior

Onychophagia, which refers to compulsive nail-biting behavior, is common among children and young adults. Onychophagia can cause destruction to the cuticle and nail plate, leading to shortening of nails, chronic paronychia, and secondary infections. Relatively uncommon effects include pigmentary changes, such as longitudinal melanonychia and splinter hemorrhages. We report a case of a young adult with longitudinal melanonychia, splinter hemorrhages, punctate leukonychia, and pterygium inversum unguis, concurrently induced by onychophagia. Importantly, patients usually do not report this behavior when asked about nail-related changes. Even upon questioning, they may deny nail-biting behavior. As in many other dermatological disorders, dermoscopy can be helpful in the diagnosis of nail disorders.

Sign in / Sign up

Export Citation Format

Share Document