scholarly journals Treatment of Patients with Refractory Atopic Dermatitis Sensitized to House Dust Mites by Using Sublingual Allergen Immunotherapy

2015 ◽  
Vol 27 (1) ◽  
pp. 82 ◽  
Author(s):  
Joon-Seok Choi ◽  
Ha-Ryeong Ryu ◽  
Cheol-Hyun Yoon ◽  
Ji-Hoon Kim ◽  
Jin-Ok Baek ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
House Dust ◽  
Allergen Immunotherapy ◽  
House Dust Mites ◽  
Dust Mites

Atopic Dermatitis, House Dust Mites, and Patch Testing

Dermatitis ◽  
2002 ◽  
Vol 13 (2) ◽  
pp. 80-82
Author(s):  
Vincent Beltrani ◽  
Jon Hanifin
Keyword(s):  
Atopic Dermatitis ◽  
House Dust ◽  
Patch Testing ◽  
House Dust Mites ◽  
Dust Mites

SENSITIVITY TO HOUSE-DUST MITES IN ATOPIC DERMATITIS

Allergy ◽  
1970 ◽  
Vol 25 (1) ◽  
pp. 41-47 ◽  
Author(s):  
MILHIM ALANI ◽  
NIELS HJORTH
Keyword(s):  
Atopic Dermatitis ◽  
House Dust ◽  
House Dust Mites ◽  
Dust Mites

scholarly journals Impact of house dust mite-driven asthma on children’s school performance and activity

2021 ◽  
Author(s):  
Catalina Gómez ◽  
Judit Barrena ◽  
Vanesa García-Paz ◽  
Ana M. Plaza ◽  
Paula Crespo ◽  
...  
Keyword(s):  
Children And Adolescents ◽  
Allergic Asthma ◽  
House Dust ◽  
Allergen Immunotherapy ◽  
House Dust Mites ◽  
Dust Mites ◽  
Activity Impairment ◽  
Daily Lives ◽  
School Work ◽  
Clinical Benefits

AbstractEvidence regarding asthma’s impact on children’s daily lives is limited. This prospective and cross-sectional, observational, multicenter study assessed school/work and activity impairment in children and adolescents with allergic asthma and their caregivers and allergen immunotherapy (AIT) effects. Included patients were schooled children and adolescents (5 to 17 years) with allergic asthma due to house dust mites (HDM). Impairment of school/work (i.e., absenteeism and presenteeism) and activity was measured in patients and their caregivers using the Work Productivity Impairment Questionnaire plus Classroom Impairment Questions: Allergy Specific (WPAI + CIQ:AS). HDM allergic patients with school impairment received subcutaneous AIT with a MicroCrystalline Tyrosine-associated allergoid. WPAI + CIQ:AS and effectiveness variables were compared between baseline and 1-year post-AIT. Of the 113 patients included, 59 (52.2%) and 51 (45.1%) showed school and activity impairment, respectively, missing a mean (SD) of 37.6 (24.4) % and 42.6 (25.6) % of school and activity time, respectively. Twenty-six (23%) caregivers reported activity impairment and, of the 79 (69.9%) employed, 30 (38%) reported work impairment. Of the 65 patients with school/activities impairment, 41 (63.1%) received AIT, of which 21 (51.2%) completed 1 year of treatment. Effectiveness variables and WPAI + CIQ:AS significantly improved: Mean (SD) school impairment decreased from 39.7 (26.7) to 2.1 (7.1) % (p < 0.001) and activity impairment from 46.2 (34.6) to 1.4 (3.6) % (p < 0.001).Conclusion: Allergic asthma due to HDMs results in school/work and activity impairment in children and adolescents and their caregivers. One year of AIT provided clinical benefits and reduced school and activity impairment. What is Known:• Allergic asthma impairs children’s school performance and daily activities.• Allergen immunotherapy modifies allergic disease course and ameliorates its symptoms. What is New:• Asthma symptoms due to allergy to house dust mites impair children’s school attendance and productivity and daily activity and their caregivers’ work performance and daily lives.• Allergen immunotherapy with a house dust mite MicroCrystalline Tyrosine (MCT)-associated allergoid seems to provide clinical benefits, associated with decreased school and activity impairment, supporting it as an effective treatment option.

Atopic Dermatitis: Role of Food and House Dust Mite Allergens

PEDIATRICS ◽  
1993 ◽  
Vol 92 (2) ◽  
pp. 252-256
Author(s):  
G. J. A. Casimir ◽  
J. Duchateau ◽  
B. Gossart ◽  
Ph. Cuvelier ◽  
F. Vandaele ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
House Dust ◽  
Soya Protein ◽  
House Dust Mites ◽  
Dust Mites ◽  
Specific Igg ◽  
Exclusion Diet ◽  
Group 2 ◽  
Β Lactoglobulin ◽  
Group 1

Objective. The aim of this study was to evaluate the humoral immune response to cow milk (CM) protein, soya protein, and house dust mites in a group of 64 CM-fed infants, who had atopic dermatitis as the sole atopic manifestation, by measuring not only IgE but also specific IgG antibodies (Ab) against bovine β-lactoglobulin, soya flour aqueous extracts, and Der P1 antigens. Methods. A CM-free diet (Nan HA, Nestle) was given to these 64 CM-fed infants and the sensitivity to CM proteins was established by a positive challenge test with the offending food in improved infants. The serum was obtained just before the start of the CM-free diet, at the first consultation. The patients were classified into two groups according to their clinical response to the hypoallergenic formula. Results. Thirty-one infants (group 1) improved dramatically (positive challenge test), and 33 (group 2) did not improve with the exclusion diet but did improve after eviction of dust-producing items in the environment. The two groups were different in terms of their total IgE immunoglobulin concentration (higher in group 1, P &lt; .05) and concentration of specific IgE Ab against CM protein (more frequent in group 1, P &lt; .01). The IgG Ab concentrations against β-lactoglobulin, the major CM antigen (P &lt; 10-4), and against soya protein (P &lt; .01) were significantly more elevated in the group improved by the diet, with a threshold above which the response to the exclusion diet could be predicted as positive. On the contrary, the level of specific IgG Ab against house dust mites was four times higher in group 2 than in group 1. Twenty-nine of the 33 infants of group 2 improved after eviction of dust-producing items in the environment. Conclusions. It is proposed that specific IgG Ab concentrations against β-lactoglobulin, soya protein, and Der P1 antigen be determined in infants and children suffering from atopic dermatitis as a means of predicting the response to an exclusion diet, and a possible role of house dust mites in the pathogenicity of the disease is suggested.

Close Positive Correlation between the Lymphocyte Response to Hen Egg White and House Dust Mites in Infants with Atopic Dermatitis

2015 ◽  
Vol 166 (3) ◽  
pp. 161-169 ◽  
Author(s):  
Mitsuaki Kimura ◽  
Takaaki Meguro ◽  
Yasunori Ito ◽  
Fumika Tokunaga ◽  
Akihiko Hashiguchi ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
House Dust ◽  
Egg White ◽  
House Dust Mites ◽  
Dust Mites ◽  
Lymphocyte Response ◽  
Positive Correlation ◽  
Hen Egg White ◽  
Hen Egg

P049 Atopic dermatitis and level of house dust mites: Preliminary data

1997 ◽  
Vol 9 ◽  
pp. S165
Author(s):  
G RICCI ◽  
A PATRIZI ◽  
F SPECCHIA ◽  
L MENNA ◽  
P BOTTAU ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
House Dust ◽  
Preliminary Data ◽  
House Dust Mites ◽  
Dust Mites
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