Effectiveness of a Sensory-Enriched Early Intervention Group Program for Children With Developmental Disabilities

2016 ◽  
Vol 70 (5) ◽  
pp. 7005220010p1 ◽  
Author(s):  
Erna Imperatore Blanche ◽  
Megan C. Chang ◽  
Juliana Gutiérrez ◽  
Janet S. Gunter
Keyword(s):  
Early Intervention ◽  
Developmental Disabilities ◽  
Intervention Group ◽  
Group Program ◽  
Early Intervention Group ◽  
Children With Developmental Disabilities

Effects of an Early Intervention Group Program for Anxious and Depressed Adolescents: A Pilot Study

2001 ◽  
Vol 88 (2) ◽  
pp. 481-482 ◽  
Author(s):  
Peter Muris ◽  
Nicole Bogie ◽  
Angelina Hoogsteder
Keyword(s):  
Early Intervention ◽  
Self Efficacy ◽  
Intervention Program ◽  
Intervention Group ◽  
Self Report ◽  
Psychological Resilience ◽  
Group Program ◽  
Early Intervention Program ◽  
High Anxious ◽  
Anxiety Depression

The Resourceful Adolescent Program is an early intervention program designed to enhance psychological resilience in adolescents with emotional problems. Eight adolescents with high anxious and/or depressive symptoms were treated with this 11-session group program. Treatment effects were examined by means of self-report questionnaires of anxiety, depression, and self-efficacy. Pre- and postintervention data showed reductions in anxiety and depression scores and a concomitant increase in adolescents' self-efficacy.

scholarly journals Prediabetes in pregnancy, can early intervention improve outcomes? A feasibility study for a parallel randomised clinical trial

BMJ Open ◽  
2018 ◽  
Vol 8 (3) ◽  
pp. e018493 ◽  
Author(s):  
Ruth C E Hughes ◽  
Janet Rowan ◽  
Jonathan Williman
Keyword(s):  
Blood Glucose ◽  
New Zealand ◽  
Early Intervention ◽  
Caesarean Section ◽  
Outcome Measures ◽  
Standard Care ◽  
Intervention Group ◽  
Blood Glucose Monitoring ◽  
Oral Glucose ◽  
Early Intervention Group

ObjectiveMeasurement of glycated haemoglobin (HbA1c) in early pregnancy is routine in New Zealand to identify women with diabetes and prediabetes. However, the benefit of early intervention in women with prediabetes is inconclusive. Our aim was to test the feasibility of a two-arm parallel randomised controlled trial of standard care versus early intervention in pregnancies complicated by prediabetes.SettingTwo tertiary referral centres in New Zealand.ParticipantsWomen <14 weeks’ gestation and HbA1c ≥5.9%–6.4% (41–46 mmol/mol) measured at booking, without pre-existing diabetes.InterventionsRandomisation was done by remote web-based allocation into one of two groups. Women in the early intervention group attended an antenatal diabetes clinic, commenced daily home blood glucose monitoring, and medication was prescribed if lifestyle measures failed to maintain target blood glucose levels. Controls received lifestyle education, continued standard care with their midwife and/or obstetrician, and were asked to perform a 75 g oral glucose tolerance test at 24 weeks’ gestation with a referral to clinic if this test was positive. Both groups received lifestyle questionnaires at recruitment and in late pregnancy.Outcome measuresRecruitment rate, adherence to protocol and validation of potential primary outcomes.ResultsRecruitment rates were lower than expected, especially in Māori and Pacific women. Non-adherence to allocated treatment protocol was significant, 42% (95% CI 24% to 61%) in the early intervention group and 30% (95% CI 16% to 51%) in controls. Caesarean section and pre-eclampsia were signalled as potential primary outcomes, due to both the high observed incidence in the control group and ease of measurement.ConclusionsFor a future definitive trial, extending the gestation of eligibility and stepped-wedge cluster randomisation may overcome the identified feasibility issues. Consistent with published observational data, pre-eclampsia and emergency caesarean section could be included as primary outcome measures, both of which have a significant impact on maternal and neonatal morbidity and healthcare costs.Trial registration numberACTRN12615000904572; Pre-results.

Early intervention for children with developmental disabilities

1993 ◽  
Vol 16 (1) ◽  
pp. 23-32 ◽  
Author(s):  
J. M. H. DE MOOR ◽  
B. T. M. VAN WAESBERGHE ◽  
J. B. L. HOSMAN ◽  
D. JAEKEN ◽  
S. MIEDEMA
Keyword(s):  
Early Intervention ◽  
Developmental Disabilities ◽  
Children With Developmental Disabilities

Ulcus cruris venosum: Was bringt die frühzeitige endovenöse Ablation bei venösen Ulzerationen?

2022 ◽  
pp. 1-2
Author(s):  
Markus Stücker
Keyword(s):  
Early Intervention ◽  
Intervention Group ◽  
Cost Effective ◽  
Quality Adjusted Life Year ◽  
Ulcer Recurrence ◽  
Venous Reflux ◽  
Endovenous Ablation ◽  
Quality Adjusted Life ◽  
Early Intervention Group

<b>Importance:</b> One-year outcomes from the Early Venous Reflux Ablation (EVRA) randomized trial showed accelerated venous leg ulcer healing and greater ulcer-free time for participants who are treated with early endovenous ablation of lower extremity superficial reflux. <b>Objective:</b> To evaluate the clinical and cost-effectiveness of early endovenous ablation of superficial venous reflux in patients with venous leg ulceration. <b>Design, Setting, and Participants:</b> Between October 24, 2013, and September 27, 2016, the EVRA randomized clinical trial enrolled 450 participants (450 legs) with venous leg ulceration of less than 6 months’ duration and superficial venous reflux. Initially, 6555 patients were assessed for eligibility, and 6105 were excluded for reasons including ulcer duration greater than 6 months, healed ulcer by the time of randomization, deep venous occlusive disease, and insufficient superficial venous reflux to warrant ablation therapy, among others. A total of 426 of 450 participants (94.7%) from the vascular surgery departments of 20 hospitals in the United Kingdom were included in the analysis for ulcer recurrence. Surgeons, participants, and follow-up assessors were not blinded to the treatment group. Data were analyzed from August 11 to November 4, 2019. <b>Interventions:</b> Patients were randomly assigned to receive compression therapy with early endovenous ablation within 2 weeks of randomization (early intervention, n  =  224) or compression with deferred endovenous treatment of superficial venous reflux (deferred intervention, n  =  226). Endovenous modality and strategy were left to the preference of the treating clinical team. <b>Main Outcomes and Measures:</b> The primary outcome for the extended phase was time to first ulcer recurrence. Secondary outcomes included ulcer recurrence rate and cost-effectiveness. <b>Results:</b> The early-intervention group consisted of 224 participants (mean [SD] age, 67.0 [15.5] years; 127 men [56.7%]; 206 White participants [92%]). The deferred-intervention group consisted of 226 participants (mean [SD] age, 68.9 [14.0] years; 120 men [53.1%]; 208 White participants [92%]). Of the 426 participants whose leg ulcer had healed, 121 (28.4%) experienced at least 1 recurrence during follow-up. There was no clear difference in time to first ulcer recurrence between the 2 groups (hazard ratio, 0.82; 95% CI, 0.57–1.17; P  =  .28). Ulcers recurred at a lower rate of 0.11 per person-year in the early-intervention group compared with 0.16 per person-year in the deferred-intervention group (incidence rate ratio, 0.658; 95% CI, 0.480–0.898; P  =  .003). Time to ulcer healing was shorter in the early-intervention group for primary ulcers (hazard ratio, 1.36; 95% CI, 1.12–1.64; P  =  .002). At 3 years, early intervention was 91.6% likely to be cost-effective at a willingness to pay of £20 000 ($26 283) per quality-adjusted life year and 90.8% likely at a threshold of £35 000 ($45 995) per quality-adjusted life year. <b>Conclusions and Relevance:</b> Early endovenous ablation of superficial venous reflux was highly likely to be cost-effective over a 3-year horizon compared with deferred intervention. Early intervention accelerated the healing of venous leg ulcers and reduced the overall incidence of ulcer recurrence. <b>Trial Registration:</b> ClinicalTrials.gov identifier: ISRCTN02335796.

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