scholarly journals Predictive Model of Nonneoplastic Pathology after Endoscopic Resection of Gastric Epithelial Neoplasia

Gut and Liver ◽  
2020 ◽  
Vol 14 (2) ◽  
pp. 199-206
Author(s):  
Tae-Geun Gweon ◽  
Byung-Wook Kim ◽  
Joon Sung Kim ◽  
Sung Min Park ◽  
Jeong Seon Ji ◽  
...  
Keyword(s):  
Predictive Model ◽  
Endoscopic Resection ◽  
Gastric Epithelial Neoplasia

Pathologic validation of ablation therapy for gastric epithelial neoplasia: comparison of argon plasma coagulations vs. coagulation forceps.

2017 ◽  
Vol 35 (4_suppl) ◽  
pp. 82-82
Author(s):  
Byung-Wook Kim
Keyword(s):  
Endoscopic Resection ◽  
Observational Studies ◽  
Argon Plasma ◽  
Complete Removal ◽  
Coagulation Time ◽  
Ablation Therapy ◽  
Gastric Epithelial Neoplasia ◽  
Coagulation Therapy ◽  
Lesion Type ◽  
Clinical Trial Information

82 Background: Ablation therapy has been introduced as an alternative in the management of gastric epithelial neoplasia. However, most of previous studies were retrospective observational studies and has not been validated pathologically. The aim of this study was to validate the effect of ablation therapy for gastric epithelial neoplasia pathologically. Methods: After ablation therapy either by argon plasma coagulations (APC) or by coagulation forceps for gastric epithelial neoplasia, immediate endoscopic resection for the lesions was performed. Consequent histologic mappings for the lesions were followed for the residual tumors. Factors which can affect the residual tumors were analyzed. Results: Twenty nine patients among 33 patients who underwent APC (87.9%) and 21 patients among 26 patients who underwent coagulation forceps (80.8%) showed residual tumors. Factors such as type of coagulation therapy, size of the lesion, type of the lesion (elevated vs. flat) and coagulation time/cm2 of the lesion were not associated with complete removal of the lesions. Conclusions: Ablation therapy is inadequate for complete removal of gastric epithelial neoplasia and this therapy cannot replace endoscopic resection. Clinical trial information: KCT0001587.

Endoscopic resection for gastric epithelial neoplasia: How to solve pathological discrepancy and achieve curative resection?

2013 ◽  
Vol 14 (5) ◽  
pp. 231-237 ◽  
Author(s):  
Ling Yin Zhu ◽  
Jun Dai ◽  
Yun Jia Zhao ◽  
Han Bin Xue ◽  
Zhi Zheng Ge ◽  
...  
Keyword(s):  
Endoscopic Resection ◽  
Curative Resection ◽  
Gastric Epithelial Neoplasia

scholarly journals Preventing Metachronous Gastric Cancer after the Endoscopic Resection of Gastric Epithelial Neoplasia: Roles of Helicobacter pylori Eradication and Aspirin

Gut and Liver ◽  
2020 ◽  
Vol 14 (3) ◽  
pp. 281-290
Author(s):  
Jiro Watari ◽  
Toshihiko Tomita ◽  
Katsuyuki Tozawa ◽  
Tadayuki Oshima ◽  
Hirokazu Fukui ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Helicobacter Pylori ◽  
Endoscopic Resection ◽  
Gastric Epithelial Neoplasia ◽  
Metachronous Gastric Cancer

Discrepancy between endoscopic forceps biopsy and endoscopic resection in gastric epithelial neoplasia

2013 ◽  
Vol 28 (4) ◽  
pp. 1256-1262 ◽  
Author(s):  
Hyun Lim ◽  
Hwoon-Yong Jung ◽  
Young Soo Park ◽  
Hee Kyong Na ◽  
Ji Yong Ahn ◽  
...  
Keyword(s):  
Endoscopic Resection ◽  
Forceps Biopsy ◽  
Gastric Epithelial Neoplasia ◽  
Endoscopic Forceps Biopsy

scholarly journals Risk Factors and Prediction Model for Non-curative Resection of Early Gastric Cancer With Endoscopic Resection and the Evaluation

2021 ◽  
Vol 8 ◽  
Author(s):  
Xiaoqian Ma ◽  
Qian Zhang ◽  
Shengtao Zhu ◽  
Shutian Zhang ◽  
Xiujing Sun
Keyword(s):  
Gastric Cancer ◽  
Early Gastric Cancer ◽  
Prediction Model ◽  
Receiver Operating Characteristic ◽  
Predictive Model ◽  
Endoscopic Resection ◽  
Tumor Size ◽  
Curative Resection ◽  
Operating Characteristic ◽  
Resection Group

Background and Study Aim: EGC, also known as Early Gastric Cancer is known to lack the lymph node metastasis and confined along the mucosa, which is treated through an endoscopic resection procedure that includes ESD (Endoscopic Submucosal dissection) and EMR (Endoscopic Mucosal Resection). However, some cases underwent residual disease, recurrence, or additional gastrectomy because of non-curative resection. The following research aims to delineate the threat factors causing the non-curative resection as well as develop a predictive model.Patient and Methods: Effort was taken to collect all the records about the health history of pathologically diagnosed EGC who experienced endoscopic treatment in the Department of Endoscopy, the Capital Medical University, and Beijing Friendship Hospital from January 2012 to January 2020. Patients were grouped into two categories primarily; a curative resection group and finally a non-curative resection group based on the outcomes of the postoperative pathological and immunohistochemical examination results. The statistical methods used included single factor analysis, a multivariate logistic regression analysis and a chi-square test. A nomogram for the prediction of non-curative resection was constructed, which included information on age, gender, resection method, postoperative pathology, tumor size, ulcer, treatment, and infiltration depth. Receiver operating characteristic (ROC) curve analysis and calibration were performed to present the predictive accuracy of the nomogram.Results: Of 443 patients with 478 lesions who had undergone ESD or EMR for EGCs, 127 were identified as being treated non-curative resection. Older patients (>60 years), a large tumor size (>30 mm), submucosal lesion, piecemeal resection, EMR for treatment and undifferentiated tumor histology were associated with non-curative resection group. Our risk nomogram showed good discriminated performance in internal validation (bootstrap-corrected area under the receiver-operating characteristic curve, 0.881; P < 0.001).Conclusions: A validated prediction model was developed to identify people who were subject to undergoing a non-curative resection for ESD. The predictive model that we formulated is essential in providing reliable information to guide the decision-making process on the treatment for EGC before undertaking an endoscopic resection.

Sa1637 Risk Factors of Residual Tumors in Completely Resected Gastric Epithelial Neoplasia After Endoscopic Resection

2014 ◽  
Vol 79 (5) ◽  
pp. AB284
Author(s):  
Yong Hoon Kim ◽  
Gak-Won Yun ◽  
Jie-Hyun Kim ◽  
Yong Chan Lee ◽  
Jae Jun Park ◽  
...  
Keyword(s):  
Risk Factors ◽  
Endoscopic Resection ◽  
Gastric Epithelial Neoplasia
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