Improvement of the performance of PES nanocomposite membrane incorporated with citric acid-modified graphene oxide for the removal of heavy metals

2019 ◽  
Vol 171 ◽  
pp. 132-143
Author(s):  
Masoumeh Arash ◽  
Yaghoub Mansourpanah ◽  
Ali Kakanejadifard
Keyword(s):  
Heavy Metals ◽  
Graphene Oxide ◽  
Citric Acid ◽  
Nanocomposite Membrane ◽  
Modified Graphene Oxide ◽  
Removal Of Heavy Metals ◽  
Modified Graphene

scholarly journals Enhanced wound repair ability of arginine-chitosan nanocomposite membrane through the antimicrobial peptides-loaded dopmine-modified graphene oxide

2021 ◽  
Author(s):  
Chuan Fu ◽  
Zhiping Qi ◽  
Chengliang Zhao ◽  
Wenlai Kong ◽  
Hongru Li ◽  
...  
Keyword(s):  
Wound Healing ◽  
Graphene Oxide ◽  
Antimicrobial Peptides ◽  
Wound Dressing ◽  
Skin Wound ◽  
Nanocomposite Membrane ◽  
Modified Graphene Oxide ◽  
Repair Ability ◽  
Modified Graphene ◽  
Dressing Materials

Abstract Skin wound healing is a complicated and lengthy process, which is influenced by multiple factors and need a suitable cellular micro-environment. For skin wound, wound dressings remain a cornerstone of dermatologic therapy at present. The dressing material can create an effective protective environment for the wound, and the interactions between the dressing and the wound has a great impact on the wound healing efficiency. An ideal wound dressing materials should have good biocompatibility, moisturizing property, antibacterial property and mechanical strength, and can effectively prevent wound infection and promote wound healing. In this study, in order to design wound dressing materials endowed with excellent antibacterial and tissue repair properties, we attempted to load antimicrobial peptides onto dopmine-modified graphene oxide (PDA@GO) using lysozyme (ly) as a model drug. Then, functionalized GO was used to the surface modification of arginine-modified chitosan (CS-Arg) membrane. To evaluate the potential of the prepared nanocomposite membrane in wound dressing application, the surface morphology, hydrophilic, mechanical properties, antimicrobial activity, and cytocompatibility of the resulting nanocomposite membrane were analyzed. The results revealed that prepared nanocomposite membrane exhibited excellent hydrophilic, mechanical strength and antimicrobial activity, which can effectively promote cell growth and adhesion. In particular, using PDA@GO as drug carrier can effectively maintain the activity of antimicrobial peptides, and can maximize the antibacterial properties of the nanocomposite membrane. Finally, we used rat full-thickness wound models to observe wound healing, and the surface interactions between the prepared nanocomposite membrane and the wound. The results indicates that nanocomposite membrane can obviouly accelerated wound closure, and the wounds showed reduced inflammation, improved angiogenesis and accelerated re-epithelialization. Therefore, incorporation of antimicrobial peptides -functionalize graphene oxide (ly-PDA@GO) into CS-Arg membrane was a viable strategy for fabricating excellent wound dressing. Together, this study not only prepared a wound dressing with excellent tissue repair ability, but also provided a novel idea for the development of graphene oxide-based antibacterial dressing.

scholarly journals Enhanced wound repair ability of arginine-chitosan nanocomposite membrane through the antimicrobial peptides-loaded polydopamine-modified graphene oxide

2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Chuan Fu ◽  
Zhiping Qi ◽  
Chengliang Zhao ◽  
Weijian Kong ◽  
Hongru Li ◽  
...  
Keyword(s):  
Wound Healing ◽  
Graphene Oxide ◽  
Antimicrobial Peptides ◽  
Wound Dressing ◽  
Skin Wound ◽  
Nanocomposite Membrane ◽  
Modified Graphene Oxide ◽  
Repair Ability ◽  
Modified Graphene ◽  
Dressing Materials

AbstractSkin wound healing is a complicated and lengthy process, which is influenced by multiple factors and need a suitable cellular micro-environment. For skin wound, wound dressings remain a cornerstone of dermatologic therapy at present. The dressing material can create an effective protective environment for the wound, and the interactions between the dressing and the wound has a great impact on the wound healing efficiency. An ideal wound dressing materials should have good biocompatibility, moisturizing property, antibacterial property and mechanical strength, and can effectively prevent wound infection and promote wound healing. In this study, in order to design wound dressing materials endowed with excellent antibacterial and tissue repair properties, we attempted to load antimicrobial peptides onto dopmine-modified graphene oxide (PDA@GO) using lysozyme (ly) as a model drug. Then, functionalized GO was used to the surface modification of arginine-modified chitosan (CS-Arg) membrane. To evaluate the potential of the prepared nanocomposite membrane in wound dressing application, the surface morphology, hydrophilic, mechanical properties, antimicrobial activity, and cytocompatibility of the resulting nanocomposite membrane were analyzed. The results revealed that prepared nanocomposite membrane exhibited excellent hydrophilic, mechanical strength and antimicrobial activity, which can effectively promote cell growth and adhesion. In particular, using PDA@GO as drug carrier can effectively maintain the activity of antimicrobial peptides, and can maximize the antibacterial properties of the nanocomposite membrane. Finally, we used rat full-thickness wound models to observe wound healing, and the surface interactions between the prepared nanocomposite membrane and the wound. The results indicated that nanocomposite membrane can obviously accelerated wound closure, and the wounds showed reduced inflammation, improved angiogenesis and accelerated re-epithelialization. Therefore, incorporation of antimicrobial peptides-functionalize graphene oxide (ly-PDA@GO) into CS-Arg membrane was a viable strategy for fabricating excellent wound dressing. Together, this study not only prepared a wound dressing with excellent tissue repair ability, but also provided a novel idea for the development of graphene oxide-based antibacterial dressing.

scholarly journals Design, synthesis, and catalytic performance of modified graphene oxide based on a cobalt complex as a heterogenous catalyst for the preparation of aminonaphthoquinone derivatives

RSC Advances ◽  
2021 ◽  
Vol 11 (28) ◽  
pp. 17108-17115
Author(s):  
Mahnaz Mirheidari ◽  
Javad Safaei-Ghomi
Keyword(s):  
Graphene Oxide ◽  
Cobalt Complex ◽  
Catalytic Performance ◽  
Silica Particles ◽  
Design Synthesis ◽  
Spherical Silica ◽  
Modified Graphene Oxide ◽  
Spherical Silica Particles ◽  
Heterogenous Catalyst ◽  
Modified Graphene

GO@f-SiO2@Co is a heterogenous catalyst composed of spherical silica particles grafted on the surface of graphene oxide with ethylenediamine ligands and coordination with Co(ii). We assessed the activity of the catalyst for the synthesis of aminonaphthoquinones.

Enhanced flame retardancy of polypropylene by melamine-modified graphene oxide

2015 ◽  
Vol 50 (16) ◽  
pp. 5389-5401 ◽  
Author(s):  
Bihe Yuan ◽  
Haibo Sheng ◽  
Xiaowei Mu ◽  
Lei Song ◽  
Qilong Tai ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Flame Retardancy ◽  
Modified Graphene Oxide ◽  
Modified Graphene
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