Adsorption of cationic dye using novel O-amine functionalized chitosan Schiff base derivatives: isotherm and kinetic studies

2018 ◽  
Vol 130 ◽  
pp. 132-141 ◽  
Author(s):  
Ahmed Shebl ◽  
A.M. Omer ◽  
T.M. Tamer
2019 ◽  
Vol 43 (24) ◽  
pp. 9540-9554 ◽  
Author(s):  
Manimohan Murugaiyan ◽  
S. Pugal Mani ◽  
Mohamed Aboobucker Sithique

In this study, novel eco-friendly and water-soluble chitosan Schiff base derivatives have been designed for potential use in antimicrobial applications.


2020 ◽  
Vol 240 ◽  
pp. 116333 ◽  
Author(s):  
Neslihan Beyazit ◽  
Halide Sinem Çakran ◽  
Ali Cabir ◽  
Yaşar Akışcan ◽  
Cahit Demetgül

2013 ◽  
Vol 86 (11) ◽  
pp. 1791-1797 ◽  
Author(s):  
C. A. Caro ◽  
G. Cabello ◽  
E. Landaeta ◽  
J. Pérez ◽  
J. H. Zagal ◽  
...  

2016 ◽  
Vol 51 (10) ◽  
pp. 1721-1730 ◽  
Author(s):  
Tamer M. Tamer ◽  
Mohamed A. Hassan ◽  
Ahmed M. Omer ◽  
Walid M.A. Baset ◽  
Mohamed E. Hassan ◽  
...  

2020 ◽  
Vol 10 (03) ◽  
pp. 402-407
Author(s):  
Ruwaidah S. Saeed

2-mercaptobenzothiazol [1] was reacted with anhydrous carbonate sodium and ClCH2COOH in distilled water to produce a compound [2]. Compound [3] was synthesized by reaction compound [2] with SOCl2 in benzene. O,N-chitosan derivative [4] had synthesized by reacted chitosan with compound [3] in trichloromethane and pyridine. O-chitosan derivative synthesized according to the method of Fischer and Speier from the reaction of chitosan with compound [2] in distilled water in acidic media to produce compound [5]. O-(carboxyl) chitosan Schiff base derivatives [6-9] had synthesized by reaction O-(carboxyl) chitosan [5] with aromatic aldehydes (syringaldehyde, 3-methoxy,4-hydroxybenzeldehyde, 4-nitrobenzeldehyde, 4-bromobenzeldehyde). The structure of produced compounds has been characterized through their spectral and analytical data, as in fourier transform infrared (FTIR) spectra,1H-NMR, UV-vis spectroscopy, elemental analysis (CHNS), scanning electron microscope (SEM), differential scanning calorimetry (DSC), and thermo gravimetry analysis (TGA). Finally, study the antibacterial activity of some prepared polymers.


ACS Omega ◽  
2020 ◽  
Vol 5 (23) ◽  
pp. 13948-13954
Author(s):  
Nadia Q. Haj ◽  
Mohsin O. Mohammed ◽  
Luqman E. Mohammood

2019 ◽  
Vol 15 (6) ◽  
pp. 648-658 ◽  
Author(s):  
Manzoor Ahmad Malik ◽  
Shabir Ahmad Lone ◽  
Parveez Gull ◽  
Ovas Ahmad Dar ◽  
Mohmmad Younus Wani ◽  
...  

Background: The increasing incidence of fungal infections, especially caused by Candida albicans, and their increasing drug resistance has drastically increased in recent years. Therefore, not only new drugs but also alternative treatment strategies are promptly required. Methods: We previously reported on the synergistic interaction of some azole and non-azole compounds with fluconazole for combination antifungal therapy. In this study, we synthesized some non-azole Schiff-base derivatives and evaluated their antifungal activity profile alone and in combination with the most commonly used antifungal drugs- fluconazole (FLC) and amphotericin B (AmB) against four drug susceptible, three FLC resistant and three AmB resistant clinically isolated Candida albicans strains. To further analyze the mechanism of antifungal action of these compounds, we quantified total sterol contents in FLC-susceptible and resistant C. albicans isolates. Results: A pyrimidine ring-containing derivative SB5 showed the most potent antifungal activity against all the tested strains. After combining these compounds with FLC and AmB, 76% combinations were either synergistic or additive while as the rest of the combinations were indifferent. Interestingly, none of the combinations was antagonistic, either with FLC or AmB. Results interpreted from fractional inhibitory concentration index (FICI) and isobolograms revealed 4-10-fold reduction in MIC values for synergistic combinations. These compounds also inhibit ergosterol biosynthesis in a concentration-dependent manner, supported by the results from docking studies. Conclusion: The results of the studies conducted advocate the potential of these compounds as new antifungal drugs. However, further studies are required to understand the other mechanisms and in vivo efficacy and toxicity of these compounds.


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