scholarly journals Biological Effects of Magnetic Resonance Imaging on Testis Histology and Seminiferous Tubules Morphometry

2019 ◽  
Vol 34 (6) ◽  
pp. 544-552
Author(s):  
Ayoob Rostamzadeh ◽  
Seyed Hadi Anjamrooz ◽  
Mohammad Jafar Rezaie ◽  
Fardin Fathi ◽  
Mohsen Mohammadi
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Biological Effects ◽  
Seminiferous Tubules ◽  
Resonance Imaging ◽  
Testis Histology

In Vivo Biological Effects of Stereotactic Radiosurgery: A Primate Model

Neurosurgery ◽  
1990 ◽  
Vol 27 (3) ◽  
pp. 373-382 ◽  
Author(s):  
L. Dade Lunsford ◽  
Eric M. Altschuler ◽  
John C. Flickinger ◽  
Andrew Wu ◽  
Julio A. Martinez
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Basic Protein ◽  
Biological Effects ◽  
Resonance Imaging ◽  
Computed Tomographic ◽  
Protein Levels ◽  
Baboon Model ◽  
Computed Tomographic Scan

Abstract Single-fraction, closed skull, small-volume irradiation (radiosurgery) of intact intracranial structures requires accurate knowledge of radiation tolerance. We have developed a baboon model to assess the in vivo destructive radiobiological effects of stereotactic radiosurgery. Three baboons received a single-fraction, 150-Gy lesion of the caudate nucleus, the thalamus, or the pons using the 8-mm diameter collimator of the gamma unit. Serial standard neurodiagnostic tests (neurological examination, computed tomographic scan, magnetic resonance imaging, stable xenon-enhanced computed tomographic scan of cerebral blood flow, somatosensory and brain stem evoked potentials, and myelin basic protein levels of cerebrospinal fluid) were compared with preoperative studies. Magnetic resonance imaging revealed the development of a lesion at the target site between 45 and 60 days after irradiation. Deterioration of the brain stem evoked potentials preceded imaging changes when the lesion encroached on auditory pathways. Myelin basic protein levels increased subsequent to imaging changes. Postmortem neuropathological examination confirmed a well-demarcated radionecrosis of the target volume. The baboon model appears to be an excellent method to study the in vivo biological effects of radiosurgery.

scholarly journals Biological Effects and Safety in Magnetic Resonance Imaging: A Review

2009 ◽  
Vol 6 (6) ◽  
pp. 1778-1798 ◽  
Author(s):  
Valentina Hartwig ◽  
Giulio Giovannetti ◽  
Nicola Vanello ◽  
Massimo Lombardi ◽  
Luigi Landini ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Biological Effects ◽  
Resonance Imaging

scholarly journals Intensity warping for multisite MRI harmonization

2019 ◽  
Author(s):  
J Wrobel ◽  
ML Martin ◽  
R Bakshi ◽  
PA Calabresi ◽  
M Elliot ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Cross Validation ◽  
Biological Effects ◽  
Brain Magnetic Resonance Imaging ◽  
Time Frame ◽  
Resonance Imaging ◽  
Biological Features ◽  
Magnetic Resonance Imaging Mri ◽  
Short Time

AbstractIn multisite neuroimaging studies there is often unwanted technical variation across scanners and sites. These “scanner effects” can hinder detection of biological features of interest, produce inconsistent results, and lead to spurious associations. We assess scanner effects in two brain magnetic resonance imaging (MRI) studies where subjects were measured on multiple scanners within a short time frame, so that one could assume any differences between images were due to technical rather than biological effects. We propose mica (multisite image harmonization by CDF alignment), a tool to harmonize images taken on different scanners by identifying and removing within-subject scanner effects. Our goals in the present study were to (1) establish a method that removes scanner effects by leveraging multiple scans collected on the same subject, and, building on this, (2) develop a technique to quantify scanner effects in large multisite trials so these can be reduced as a preprocessing step. We found that unharmonized images were highly variable across site and scanner type, and our method effectively removed this variability by warping intensity distributions. We further studied the ability to predict intensity harmonization results for a scan taken on an existing subject at a new site using cross-validation.

Functional information from magnetic resonance imaging

1995 ◽  
Vol 53 ◽  
pp. 84-85
Author(s):  
Alan P. Koretsky ◽  
Afonso Costa e Silva ◽  
Yi-Jen Lin
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
High Resolution ◽  
Cancer Biology ◽  
Imaging Modality ◽  
Magnetic Resonance Images ◽  
Great Success ◽  
Functional Information ◽  
Resonance Imaging ◽  
High Resolution Mri

Magnetic resonance imaging (MRI) has become established as an important imaging modality for the clinical management of disease. This is primarily due to the great tissue contrast inherent in magnetic resonance images of normal and diseased organs. Due to the wide availability of high field magnets and the ability to generate large and rapidly switched magnetic field gradients there is growing interest in applying high resolution MRI to obtain microscopic information. This symposium on MRI microscopy highlights new developments that are leading to increased resolution. The application of high resolution MRI to significant problems in developmental biology and cancer biology will illustrate the potential of these techniques.In combination with a growing interest in obtaining high resolution MRI there is also a growing interest in obtaining functional information from MRI. The great success of MRI in clinical applications is due to the inherent contrast obtained from different tissues leading to anatomical information.

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