scholarly journals Spinal Tuberculosis Presenting as Abdominal Pain: Rare Presentation of a Common Disease

2014 ◽  
Vol 29 (2) ◽  
Author(s):  
Sanjay Meena ◽  
Nilesh Barwar ◽  
Tusshar Gupta ◽  
Buddhadev Chowdhury
Keyword(s):  
Abdominal Pain ◽  
Spinal Tuberculosis ◽  
Common Disease ◽  
Rare Presentation

scholarly journals Cutaneous Metastasis of Prostate Adenocarcinoma: A Rare Presentation of a Common Disease

2021 ◽  
Vol 9 ◽  
pp. 232470962199076
Author(s):  
Alexander Dills ◽  
Okechukwu Obi ◽  
Kevin Bustos ◽  
Jesse Jiang ◽  
Shweta Gupta
Keyword(s):  
Prostate Cancer ◽  
Serine Proteases ◽  
Cancer Genetics ◽  
Performance Status ◽  
Distant Metastases ◽  
The United States ◽  
Cutaneous Metastasis ◽  
Common Disease ◽  
Cutaneous Metastases ◽  
Rare Presentation

Prostate cancer is the most common cancer affecting men in the United States and the second greatest cause of cancer-related death. Metastases usually occur to bone followed by distant lymph nodes and then viscera. Cutaneous metastases are extremely rare. Their presence indicates advanced disease and a poor prognosis. As they are highly variable in appearance and may mimic a more benign process, biopsy is essential for identification. Serine proteases, particularly human tissue kallikreins, may play an important role in promoting metastasis and facilitate infiltration of the skin. Individual cancer genetics may predispose to more aggressive cancer and thus earlier and more distant metastases. In this article, we report our case of a 67-year-old man with a 4-year history of castrate-resistant prostate cancer with cutaneous metastases confirmed by histology. Despite multiple lines of systemic therapy, the patient suffered progressive disease with worsening performance status and was enrolled in hospice.

Imperforate hymen mimicking acute appendicitis in an adolescent woman: a rare presentation

2021 ◽  
Vol 14 (3) ◽  
pp. e238547
Author(s):  
Victoria Rose Russell ◽  
Mohamed Ibrahim ◽  
Georgina Phillips ◽  
Tom Setchell ◽  
Sanjay Purkayastha
Keyword(s):  
Abdominal Pain ◽  
Acute Appendicitis ◽  
Iliac Fossa ◽  
Female Genital Tract ◽  
Delayed Diagnosis ◽  
Rare Presentation ◽  
Left Iliac Fossa ◽  
Imperforate Hymen ◽  
Retrograde Menstruation ◽  
Low Incidence

Imperforate hymen is a rare congenital malformation of the female genital tract. The condition poses several diagnostic challenges owing to its low incidence and often atypical presentation. Classical symptoms include amenorrhoea and cyclical abdominal pain. Delayed diagnosis leads to potentially irreversible and lifechanging sequelae including infertility, endometriosis and renal failure. A premenarchal 13-year-old girl with a background of chronic constipation presented with symptoms mimicking acute appendicitis. The underlying cause was imperforate hymen and retrograde menstruation. The diagnosis was made during diagnostic laparoscopy. As with this patient, pre-existing symptoms are often troublesome long before the true diagnosis is made. This case report highlights the importance of recognising imperforate hymen as a potential cause of acute abdominal pain in premenarchal adolescent girls. The clinical picture may present as right or left iliac fossa pain. Early identification reduces the risk of adverse complications and avoids unnecessary and potentially harmful interventions.

scholarly journals Primary Esophageal Intramural Squamous Cell Carcinoma Masquerading as a Submucosal Tumor: A Rare Presentation of a Common Disease

2016 ◽  
Vol 9 ◽  
pp. CGast.S40605 ◽  
Author(s):  
Nikhil Sonthalia ◽  
Samit S. Jain ◽  
Ravindra G. Surude ◽  
Vinay B. Pawar ◽  
Suhas Udgirkar ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Submucosal Tumor ◽  
Muscularis Propria ◽  
Upper Gastrointestinal Endoscopy ◽  
Common Disease ◽  
Esophageal Tumor ◽  
Rare Presentation ◽  
Tomography Scan

Esophageal squamous cell carcinoma (ESCC) is the commonest primary malignant esophageal tumor, which typically presents as endoscopically visible surface mucosal ulcerations, irregularities, or polyploidal masses. We here report a rare case of primary ESCC with completely intramural growth under a normal looking intact nondysplastic surface squamous epithelium disguising as a submucosal tumor. Upper gastrointestinal endoscopy-guided mucosal biopsy was negative for malignancy. Endoscopic ultrasound (EUS) revealed a heteroechoic solid mass originating from the muscularis propria of the distal esophagus. Cytological study of EUS-guided fine needle aspiration from the mass was suggestive of squamous cell carcinoma, which was confirmed on immunohistochemistry. There was no evidence of metastatic origin of this tumor or continuous cancer involvement from the surrounding structures, including the head, neck, and lungs on bronchoscopy, computed tomography scan, and positron emission tomography scan. Exclusive intramural squamous cell carcinoma with normal overlying mucosa is an exceedingly rare presentation of primary ESCC with only four cases reported in the literature so far. A high index of suspicion is required by the gastroenterologists and pathologists in diagnosing these cases as these tumors closely mimic the mesenchymal submucosal tumors such as lipoma, leiomyoma, and gastrointestinal stromal tumors. EUS is an indispensable tool in making a preoperative diagnosis and therapeutic decision making.

scholarly journals Pemphigus Vegetans of Neumann Type on Lip: A Case Report

2021 ◽  
Vol 7 (4) ◽  
Author(s):  
Anil P Gosavi ◽  
Ravindranath Brahmadeo Chavan ◽  
Jheel Shriniwas Ambike ◽  
Nitika S Deshmukh
Keyword(s):  
Case Report ◽  
Rare Variant ◽  
Pemphigus Vulgaris ◽  
Common Disease ◽  
Middle Aged ◽  
Rare Presentation ◽  
Neumann Type ◽  
Pemphigus Vegetans ◽  
Intralesional Steroids

: Pemphigus is a chronic autoimmune vesiculobullous disease caused by autoantibodies directed against desmogleins (Dsgs). Pemphigus vegetans is a rare variant of pemphigus vulgaris, characterized by vegetative plaques, primarily occurring in flexures. It is a less common disease and involves the skin and mucosa due to disintegration of cellular adherence (acantholysis), resulting in intradermal split. We report this case of pemphigus vegetans of Neumann type for its rare presentation. We report a case of pemphigus vegetans, involving lips in a middle-aged female and sparing flexural areas. This patient was diagnosed on the basis of histopathology and treated successfully with intralesional steroids, resulting in the resolution of her plaques.

scholarly journals Emergency surgical management of sub-hepatic appendicular perforation with abscess; rare presentation of a common disease: a case report

2021 ◽  
Vol 9 (11) ◽  
pp. 3478
Author(s):  
S. K. Sekendar Ali ◽  
Narendra Nath Mukhopadhyay
Keyword(s):  
Case Report ◽  
Surgical Management ◽  
Perforated Appendicitis ◽  
Exploratory Laparotomy ◽  
Clinical Suspicion ◽  
Common Disease ◽  
Emergency Setting ◽  
Atypical Presentation ◽  
Rare Presentation ◽  
High Level

Subhepatic appendicitis is a very rare presentation that has been rarely reported, accounting for 0.01% of acute appendicitis case. It is difficult to diagnose and prime to be aware of variants, manage such challenging case in emergency setting. We present a case of 29 years male patient with subhepatic perforated appendicitis and its sequelae-abscess and peritonitis who underwent an exploratory laparotomy and appendectomy. The initial diagnosis and surgical management of such patients is challenging due to very rare and atypical presentation in emergency setting. A high level of clinical suspicion, promote decision to operate and skillful surgical approach is discussed with briefly.

scholarly journals A rare presentation of benign Brenner tumor of ovary: a case report

2018 ◽  
Vol 7 (7) ◽  
pp. 2971
Author(s):  
Sumathi Periasamy ◽  
Subha Sivagami Sengodan ◽  
Devipriya . ◽  
Anbarasi Pandian
Keyword(s):  
Abdominal Pain ◽  
Ovarian Tumor ◽  
Ovarian Neoplasms ◽  
Pelvic Mass ◽  
Ovarian Tumors ◽  
Pathological Examination ◽  
Rare Presentation ◽  
Brenner Tumor ◽  
Benign Nature ◽  
Brenner Tumors

Brenner tumors are rare ovarian tumors accounting for 2-3% of all ovarian neoplasms and about 2% of these tumors are borderline (proliferating) or malignant. These tumors are commonly seen in 4th-8th decades of life with a peak in late 40s and early 50s. Benign Brenner tumors are usually small, <2cm in diameter and often detected incidentally during surgery or on pathological examination. Authors report a case of a large, calcified benign Brenner tumor in a 55-year-old postmenopausal woman who presented with complaint of abdominal pain and mass in abdomen. Imaging revealed large complex solid cystic pelvic mass -peritoneal fibrosarcoma. She underwent laparotomy which revealed huge Brenner tumor weighing 9kg arising from left uterine cornual end extending up to epigastric region. Myomectomy and hysterectomy with bilateral salphingo oophorectomy, omentectomy done and the specimen was sent for histopathological and immunohistochemistry study which revealed benign Brenner tumor. Brenner tumors are rare ovarian neoplasms accounting for 2-3% of all ovarian tumors. Benign Brenner tumors are usually small and solid whereas borderline and malignant Brenner tumors are usually larger and cystic with solid areas. But it is possible to have a completely benign large Brenner tumor. Therefore, benign nature of the lesion should not be excluded even when the ovarian tumor is very large.

Extramedullary haematopoiesis presenting as a periportal mass

2020 ◽  
Vol 13 (7) ◽  
pp. e235064
Author(s):  
Faranak Rafiee ◽  
Sara Haseli ◽  
Seyed Hamed Jafari ◽  
Pooya Iranpour
Keyword(s):  
Bone Marrow ◽  
Abdominal Pain ◽  
Histopathological Examination ◽  
Final Diagnosis ◽  
Extramedullary Haematopoiesis ◽  
Abdominal Ct ◽  
Rare Presentation ◽  
Abdominal Ct Scan ◽  
History Of ◽  
Vague Abdominal Pain

Extramedullary haematopoiesis (EMH) is defined as haematopoiesis occurring in organs outside the bone marrow. The liver is one of the rare sites of EMH, and to the best of our knowledge, a few cases of adult EMH of the liver have been reported in the last 20 years. Here, we reported the case of a 68-year-old man with a known history of myelofibrosis presented with vague abdominal pain. An abdominal CT scan showed a hypoattenuating periportal mass encasing the portal vein. The final diagnosis of EMH was made through the histopathological examination. This is a rare presentation of EMH, which may be easily mistaken for other pathologies such as metastases. Familiarity with this type of presentation aids in correctly diagnosing it in an appropriate clinical setting.

Multiple Myeloma With Lymphadenopathy And Mixed Lytic-Blastic Bone Lesions- A Rare Presentation Of Common Disease

2012 ◽  
Author(s):  
Setu Patolia ◽  
Francis Schmidt ◽  
Neerja Gulati ◽  
Perwaiz K. Muhammad ◽  
Dharani Kumari Narendra ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Bone Lesions ◽  
Common Disease ◽  
Rare Presentation

scholarly journals The real cause of right lower abdominal pain: an analysis of ultrasonographic findings

2020 ◽  
Vol 48 (8) ◽  
pp. 030006052094618
Author(s):  
Xia Zhang ◽  
Biaohu Liu ◽  
Xiangming Zhu ◽  
Guobing Hu
Keyword(s):  
Abdominal Pain ◽  
Histopathological Examination ◽  
Splenic Vein ◽  
Lower Abdominal Pain ◽  
Accessory Spleen ◽  
Large Mass ◽  
Splenic Tissue ◽  
Common Disease ◽  
Ureteral Calculus ◽  
The Right

A pelvic accessory spleen is uncommon and most patients with this condition are asymptomatic. Ureteral calculus is a common disease and can cause acute abdominal pain. We report a 51‐year‐old male patient who presented at our hospital with acute right lower abdominal pain and gross hematuria. A large mass on the right side of the pelvis was detected on an ultrasound examination, as well as a calculus in the lower segment of the right ureter. Computed tomography angiography showed the presence of a long vascular pedicle with an artery originating from the splenic artery and a vein that joined with the splenic vein. Laparoscopy was carried out and it showed a solid mass covered with omentum on the right lower abdomen. The mass was then removed surgically. Histopathological examination of the resected specimens confirmed splenic tissue. We speculate that the accessory spleen and ureteral calculus caused right lower abdominal pain in our case. However, the ureteral calculus might have played a much more important role in causing acute right lower abdominal pain than the accessory spleen.

CAVITARY SARCOIDOSIS: A RARE PRESENTATION OF A COMMON DISEASE

CHEST Journal ◽  
2019 ◽  
Vol 155 (4) ◽  
pp. 272A
Author(s):  
T. Dempsey ◽  
A. Patel
Keyword(s):  
Common Disease ◽  
Rare Presentation
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