Disease progression to chronic migraine: onset of symptoms of headaches, anxiety and mood disorders

2011 ◽  
pp. 5-9
Author(s):  
Juliane P. P. Mercante ◽  
Mario F. P. Peres ◽  
Marcio A. Bernik ◽  
Felipe Corchs ◽  
Vera Z. Guendler ◽  
...  
Keyword(s):  
Anxiety Disorders ◽  
Psychiatric Disorders ◽  
Chronic Migraine ◽  
Disease Progression ◽  
Mood Disorders ◽  
International Headache Society ◽  
Episodic Migraine ◽  
Migraine Progression ◽  
History Of

Background: Psychiatric conditions, mostly anxiety and mood disorders, are common in patients with chronic migraine. There has recently been extensive debate on migraine progression, but little is known about the role of psychiatric disorders in this respect. Objective: In order to evaluate the role of psychiatric disorders in migraine progression, we analyzed the temporal profile of migraine, mood and anxiety disorders, and years since onset of symptoms in chronic migraine (CM) patients. Methods: Fifty CM patients diagnosed according to the International Headache Society (2004) criteria were interviewed and diagnosed for mental disorders using the Structured Clinical Interview for DSM-IV (SCID-I/P). Results: Anxiety disorders preceded the onset of episodic migraine, which was followed by depression and daily headaches. Conclusions: Psychiatric comorbidity evaluation in chronic migraine may lead to better patient management and clinical outcomes. Patients with a history of anxiety, episodic migraine, and depression may be at risk of developing CM. Early treatment of anxiety, mood disorders, and episodic migraine may prevent disease progression to CM.

scholarly journals Phobias, other psychiatric comorbidities and chronic migraine

2006 ◽  
Vol 64 (4) ◽  
pp. 950-953 ◽  
Author(s):  
Felipe Corchs ◽  
Juliane P.P. Mercante ◽  
Vera Z. Guendler ◽  
Domingos S. Vieira ◽  
Marcelo R. Masruha ◽  
...  
Keyword(s):  
Anxiety Disorder ◽  
General Population ◽  
Anxiety Disorders ◽  
Mental Disorder ◽  
Psychiatric Disorders ◽  
Chronic Migraine ◽  
Mood Disorders ◽  
Early Treatment ◽  
Anxiety And Depression ◽  
Dsm Iv

BACKGROUND: Comorbidity of chronic migraine (CM) with psychiatric disorders, mostly anxiety and mood disorders, is a well-recognized phenomenon. Phobias are one of the most common anxiety disorders in the general population. Phobias are more common in migraineurs than non-migraineurs. The clinical profile of phobias in CM has never been studied. METHOD: We investigated the psychiatric profile in 56 patients with CM using the SCID I/P interview. RESULTS: Lifetime criteria for at least one mental disorder was found in 87.5% of the sample; 75% met criteria for at least one lifetime anxiety disorder and 60.7% of our sample fulfilled DSM-IV criteria for lifetime phobic avoidant disorders. Mood and anxiety scores were higher in phobic patients than in non-phobic CM controls. Number of phobias correlated with higher levels of anxiety and depression. CONCLUSION: Phobias are common in CM. Its recognition may influence its management. Early treatment may lead to better prognosis.

scholarly journals Identifying Cutaneous Allodynia in Chronic Migraine Using a Practical Clinical Method

Cephalalgia ◽  
2007 ◽  
Vol 27 (2) ◽  
pp. 111-117 ◽  
Author(s):  
A Ashkenazi ◽  
M Sholtzow ◽  
JW Shaw ◽  
R Burstein ◽  
WB Young
Keyword(s):  
Chronic Migraine ◽  
Demographic Data ◽  
Poor Response ◽  
Practical Method ◽  
Episodic Migraine ◽  
Entire Study ◽  
Clinical Method ◽  
Cutaneous Allodynia ◽  
History Of ◽  
Acute Headache

Cutaneous allodynia is common in migraine. In the majority of previous studies on allodynia in migraine, only patients with episodic migraine (EM) were included. Little is known on patterns of allodynia in chronic migraine (CM). Since the presence of allodynia is associated with a poor response to triptans, a clinically practical method to test migraine patients for allodynia would be useful to the clinician. The aim of this study was to assess the prevalence of dynamic mechanical (brush) allodynia (BA) in CM, using a clinically practical method. Eighty-nine CM patients were prospectively recruited. Patients were given a structured questionnaire regarding demographic data and migraine characteristics. Allodynia was tested using a 10 x 10-cm gauze pad to brush various areas of the skin lightly. The prevalence of BA in the entire study population and in different patient subgroups was calculated. BA was present in 42.7% (38/89) of the patients. The presence of allodynia was unrelated to age, disease duration or to the occurrence of an acute headache exacerbation at the time of testing. Allodynia was positively associated with a history of migraine aura. BA was most common in the cephalic area, but was also seen in cervical dermatomes. BA is common in CM and, unlike in EM, is not significantly affected by the occurrence of an acute headache exacerbation. This suggests that central trigeminovascular neurons are chronically sensitized in patients experiencing migraine headache >15 days per month. The testing of BA in the clinical setting is possible using a simple and brief approach. It allows the clinician to determine whether the patient is sensitized, a diagnosis that affects treatment decisions.

scholarly journals 089 Breaking the cycle of chronic daily headache with a low-dose subcutaneous lignocaine and ketamine infusion

2019 ◽  
Vol 90 (e7) ◽  
pp. A28.3-A29
Author(s):  
Christopher JF Rofe ◽  
Raymond Garrick ◽  
David Burke ◽  
Bruce J Brew ◽  
Susan E Tomlinson
Keyword(s):  
Chronic Migraine ◽  
Episodic Migraine ◽  
Management Plan ◽  
Motor Axons ◽  
Ketamine Infusion ◽  
Pain Pathways ◽  
History Of ◽  
Observational Cohort ◽  
Daily Headache ◽  
Rebound Headache

IntroductionManagement of chronic migraine includes correcting analgesic rebound headache and implementing suitable medication for prevention and acute episodes. However, in many cases this management paradigm oversimplifies the complexity of chronic migraine, particularly the entrenched central pathways that perpetuate chronic migraine. Intravenous lignocaine can curtail chronic migraine and analgesic rebound headache (1). Further, ketamine provides short-term analgesia and enables reduction in central sensitisation of pain pathways, particularly in the setting of codeine/opiod overuse (2). This paper describes use of subcutaneous lignocaine and ketamine infusion in chronic migraine.MethodsA prospective observational cohort study was undertaken in patients with chronic migraine. Patients received a prolonged subcutaneous lignocaine and ketamine infusion (mean duration 11 days) and underwent evaluation at four-time points over six months. The effects on the excitability of motor axons in the median nerve were documented using standard procedures.ResultsFourteen patients were recruited. The infusion was well tolerated; no major side effects were seen. There were no significant long-term changes in the excitability of motor axons. At six months, 13/14 patients had sustained benefit. Three of 4 patients remained free of analgesic rebound headache. One patient remained headache-free. Conversion to episodic migraine occurred in 6/14. Improvement in chronic migraine was reported by 6/14. Three of six were able to return to work, with 1 returning to studies. Benefit was greater in those with depression and history of opiod/codeine use.ConclusionSubcutaneous lignocaine and ketamine can help break entrenchment in chronic migraine as part of a structured management plan.

Brain Hemispheric Organization, Anxiety, and Psychoses

CNS Spectrums ◽  
2000 ◽  
Vol 5 (9) ◽  
pp. 58-69 ◽  
Author(s):  
Silvana Galderisi ◽  
Armida Mucci ◽  
Mario Maj
Keyword(s):  
Panic Disorder ◽  
Anxiety Disorders ◽  
Psychiatric Disorders ◽  
Obsessive Compulsive Disorder ◽  
Theoretical Models ◽  
Developmental Perspective ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Hemispheric Functioning

AbstractAbnormalities of brain hemispheric organization have been found in a variety of psychiatric disorders. Despite the great amount of data collected and the number of theoretical models elaborated, the role of these abnormalities in the pathogenesis of these disorders remains controversial. This article briefly reviews current concepts of hemispheric functioning, discusses the role of abnormalities of brain hemispheric organization in schizophrenia and in two anxiety disorders (panic disorder and obsessive-compulsive disorder), and outlines a developmental perspective that accounts for the observed abnormalities.

scholarly journals 0900 NATURAL HISTORY OF INSOMNIA SYMPTOMS AND INCIDENCE OF PSYCHIATRIC DISORDERS: ROLE OF CHILDHOOD-ONSET, ADOLESCENCE-ONSET AND FULL REMISSION

SLEEP ◽  
2017 ◽  
Vol 40 (suppl_1) ◽  
pp. A334-A335
Author(s):  
J Baker ◽  
S Frye ◽  
J Fernandez-Mendoza ◽  
SL Calhoun ◽  
AN Vgontzas ◽  
...  
Keyword(s):  
Natural History ◽  
Psychiatric Disorders ◽  
Childhood Onset ◽  
Full Remission ◽  
History Of ◽  
Insomnia Symptoms

scholarly journals Vertebral artery hypoplasia and chronic migraine: is there an association or just an incidental finding?

2021 ◽  
pp. 148-151
Author(s):  
Patrick Emanuell Mesquita Sousa Santos ◽  
Gabriela Figueiredo Pucci ◽  
Juliana Akita
Keyword(s):  
Risk Factors ◽  
Vertebral Artery ◽  
Psychiatric Disorders ◽  
Chronic Migraine ◽  
Incidental Finding ◽  
Episodic Migraine ◽  
Psychiatric Comorbidities ◽  
Vertebral Artery Hypoplasia

We describe a 29-year-old woman with chronic migraine and psychiatric comorbidities that presented with new transient left-sided hemiparesis and hemi-hypoesthesia and were found to have right vertebral artery hypoplasia (VAH). We briefly review the association of VAH and migraine and the influence of psychiatric disorders and VAH as possible risk factors for chronification of episodic migraine. Despite uncertain mechanisms, VAH may be one of thecontributing factors for the chronicity of migraine.

Psychiatric Comorbidity in Migraine: A Review

Cephalalgia ◽  
2005 ◽  
Vol 25 (3) ◽  
pp. 165-178 ◽  
Author(s):  
F Radat ◽  
J Swendsen
Keyword(s):  
Substance Abuse ◽  
Major Depression ◽  
Anxiety Disorders ◽  
Psychiatric Disorders ◽  
Mood Disorders ◽  
Psychiatric Comorbidity ◽  
Depression And Anxiety ◽  
Transformed Migraine ◽  
Cross Transmission ◽  
Psychiatric Conditions

Investigations of migraine comorbidity have confirmed its association with diverse psychiatric conditions. This association appears to be strongest for major depression and anxiety disorders (particularly panic and phobia), but increased comorbidity has also been reported with substance abuse and certain mood disorders. This literature also indicates that greater psychiatric comorbidity exists for migraine sufferers with aura than without. Some support is found for the notion that psychiatric comorbidity is higher in transformed migraine than in simple migraine (particularly in the case of chronic substance abuse). However, research into the possible mechanisms underlying these associations remains limited. Studies examining the order of onset and the cross-transmission of migraine and psychiatric disorders in families have been unable to distinguish fully between causal and common aetiological models of association. The conclusions are discussed in light of both methodological and conceptual issues relevant to understanding migraine comorbidity.

Psychiatric disorders and biological factors

2019 ◽  
pp. 33-44
Author(s):  
Navneet Kapur ◽  
Robert Goldney
Keyword(s):  
Psychiatric Disorders ◽  
Mood Disorders ◽  
Suicidal Behaviour ◽  
Biological Factors ◽  
Hypothalamic Pituitary Adrenal ◽  
Important Interaction ◽  
Increase Risk ◽  
Physical Disorders ◽  
Drug And Alcohol

This chapter discusses the role of psychiatric disorders, biological factors, and genetic factors in suicidal behaviour. These increase risk and the susceptibility of some individuals to react more severely to stress but do not inevitably lead to suicide. All psychiatric disorders are associated with a higher risk of suicide, particularly mood disorders, schizophrenia, and drug and alcohol misuse. Comorbidity (multiple psychiatric disorders at the same time or psychiatric and physical disorders together) is common. The vulnerability to suicidal behaviour is partly inherited. The serotonin and hypothalamic–pituitary–adrenal systems are associated with suicide; however biological factors lack specificity. There is an important interaction between genetic susceptibility and the environment—stressors may have more of an impact in individuals who carry particular genes.

scholarly journals Lifetime prevalence of psychiatric disorders in South Africa

2008 ◽  
Vol 192 (2) ◽  
pp. 112-117 ◽  
Author(s):  
Dan J. Stein ◽  
Soraya Seedat ◽  
Allen Herman ◽  
Hashim Moomal ◽  
Steven G. Heeringa ◽  
...  
Keyword(s):  
Mental Health ◽  
South Africa ◽  
Substance Use ◽  
Anxiety Disorders ◽  
Psychiatric Disorders ◽  
Mood Disorders ◽  
Ethnic Groups ◽  
Substance Use Disorders ◽  
Age At Onset ◽  
Lifetime Prevalence

BackgroundData on the lifetime prevalence of psychiatric disorders in South Africa are of interest, not only for the purposes of developing evidence-based mental health policy, but also in view of South Africa's particular historical and demographic circumstances.MethodA nationally representative household survey was conducted between 2002 and 2004 using the World Health Organization Composite International Diagnostic Interview (CIDI) to generate diagnoses. The data-set analysed included 4351 adult South Africans of all ethnic groups.ResultsLifetime prevalence of DSM–IV/CIDI disorders was determined for anxiety disorders (15.8%), mood disorders (9.8%), substance use disorders (13.4%) and any disorder (30.3%). Lifetime prevalence of substance use disorders differed significantly across ethnic groups. Median age at onset was earlier for substance use disorders (21 years) than for anxiety disorders (32 years) or mood disorders (37 years).ConclusionsIn comparison with data from other countries, South Africa has a particularly high lifetime prevalence of substance use disorders. These disorders have an early age at onset, providing an important target for the planning of local mental health services.

scholarly journals Relationship between adult social phobia and childhood anxiety

2003 ◽  
Vol 25 (2) ◽  
pp. 96-99 ◽  
Author(s):  
Gisele Gus Manfro ◽  
Luciano Isolan ◽  
Carolina Blaya ◽  
Sandra Maltz ◽  
Elizeth Heldt ◽  
...  
Keyword(s):  
Risk Factor ◽  
Anxiety Disorder ◽  
Family History ◽  
Anxiety Disorders ◽  
Social Phobia ◽  
Psychiatric Disorders ◽  
Childhood Anxiety ◽  
Adult Patients ◽  
Childhood Anxiety Disorders ◽  
History Of

OBJECTIVE: The aim of this study was to evaluate the prevalence of traumas and the presence of childhood anxiety disorders in adult patients with social phobia and investigate their influence on the presentation of the disorder. METHODS: Twenty-four adult patients with social phobia were asked about the presence of trauma before the age of 16. The K-SADS-E and the DICA-P interviews were used to assess these patients regarding childhood anxiety disorders. RESULTS: Twelve (50%) patients reported a history of trauma before the age of 16. The presence of trauma did not influence the presentation of the disorder. Seventy-five percent of patients had a history of anxiety disorders in childhood. Patients with a history of at least 2 childhood anxiety disorders had an increased lifetime prevalence of major depression (10 vs. 3; p=.04) and family history of psychiatric disorders (13 vs. 6; p=.02). CONCLUSION: Anxiety disorder in childhood is associated with family history of psychiatric disorders. The presence of more than one diagnosis of anxiety disorder in childhood can be considered a risk factor for the development of depression in adult patients with social phobia.

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