The role of drug-induced sleep endoscopy for positive airway pressure titration – initial results

2021 ◽  
Vol 84/117 (2) ◽  
Author(s):  
Michaela Masárová ◽  
Jana Seko ◽  
Marek Plášek ◽  
Martin Formánek ◽  
Ondřej Jor ◽  
...  
Keyword(s):  
Airway Pressure ◽  
Positive Airway Pressure ◽  
Sleep Endoscopy ◽  
Drug Induced ◽  
Drug Induced Sleep Endoscopy ◽  
Initial Results

scholarly journals The Emerging Role of Drug-Induced Sleep Endoscopy in the Management of Obstructive Sleep Apnea

2020 ◽  
Author(s):  
Crystal SJ Cheong ◽  
Weiqiang Loke ◽  
Mark Kim Thye Thong ◽  
Song Tar Toh ◽  
Chi-Hang Lee
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Airway Pressure ◽  
Positive Airway Pressure ◽  
Upper Airway ◽  
Sleep Endoscopy ◽  
Drug Induced ◽  
Drug Induced Sleep Endoscopy ◽  
Obstructive Sleep

Obstructive sleep apnea is a prevalent sleep disorder characterized by partial or complete obstruction of the upper airway. Continuous positive airway pressure is the first-line therapy for most patients, but compliance is often poor. Alternative treatment options such as mandibular advancement devices, positional therapy and surgical interventions including upper airway stimulation target different levels and patterns of obstruction with varying degrees of success. Drug-induced sleep endoscopy enables visualization of upper airway obstruction under conditions mimicking sleep. In an era of precision medicine, this additional information may facilitate better decision-making when prescribing alternative treatment modalities, with the hope of achieving better compliance and/or success rates. This review discusses the current knowledge and evidence on the role of drug-induced sleep endoscopy in the non-positive airway pressure management of obstructive sleep apnea.

scholarly journals Drug-Induced Sleep Endoscopy Changes the Treatment Concept in Patients with Obstructive Sleep Apnoea

2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Jaroslava Hybášková ◽  
Ondřej Jor ◽  
Vilém Novák ◽  
Karol Zeleník ◽  
Petr Matoušek ◽  
...  
Keyword(s):  
Obstructive Sleep Apnoea ◽  
Airway Pressure ◽  
Positive Airway Pressure ◽  
Sleep Apnoea ◽  
Treatment Concept ◽  
Sleep Endoscopy ◽  
Upper Airways ◽  
Drug Induced ◽  
Drug Induced Sleep Endoscopy ◽  
Obstructive Sleep

The present study evaluated whether drug-induced sleep endoscopy (DISE) helps identify the site of obstruction in patients with obstructive sleep apnoea (OSA). A total of 51 consecutive patients with polysomnography-confirmed OSA were enrolled in this prospective study. The presumed site of obstruction was determined according to history, otorhinolaryngologic examination, and polysomnography and a therapeutic plan designed before DISE. In 11 patients with severe OSA and/or previously failed continuous positive airway pressure (CPAP) treatment, DISE with simultaneous CPAP was performed. Multilevel collapse was noted in 49 patients (96.1%). The most frequent multilevel collapse was palatal, oropharyngeal, and tongue base collapse (n=17, 33.3%), followed by palatal and oropharyngeal collapse (n=12, 23.5%). Pathology of the larynx (epiglottis) was observed in 16 patients (31.4%). The laryngeal obstruction as a reason for intolerance of CPAP was observed in 3/11 (27.3%) patients. After DISE, the surgical plan was changed in 31 patients (60.8%). The results indicate that DISE helps identify the site of obstruction in the upper airways in patients with OSA more accurately and that the larynx plays an important role in OSA.

The Role of Drug-induced Sleep Endoscopy in Treatment (Surgical and Non-surgical) in Patients with Obstructive Sleep Apnea

2017 ◽  
Vol 80/113 (4) ◽  
pp. 428-433
Author(s):  
Jaroslava Hybášková ◽  
Ondřej Jor ◽  
Vilém Novák ◽  
Petr Matoušek ◽  
Pavel Komínek
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Sleep Endoscopy ◽  
Drug Induced ◽  
Drug Induced Sleep Endoscopy ◽  
Obstructive Sleep

scholarly journals Drug-induced sleep endoscopy – decisional factor in obstructive sleep apnea treatment

2018 ◽  
Vol 8 (30) ◽  
pp. 77-85
Author(s):  
Nicoleta Dumitrescu ◽  
Codrut Sarafoleanu
Keyword(s):  
Sleep Apnea ◽  
Positive Airway Pressure ◽  
Specific Treatment ◽  
Sleep Endoscopy ◽  
Drug Induced ◽  
Drug Induced Sleep Endoscopy ◽  
Appropriate Treatment ◽  
Obstructive Sleep ◽  
Direct View ◽  
Sleep Apnea Treatment

Abstract BACKGROUND. Drug-Induced Sleep Endoscopy (DISE) is a sleep apnea diagnostic procedure which allows direct view the obstruction while inducing sleep using analgosedation with propofol. Many studies highlighted the importance of DISE in finding the level of obstruction and choosing the specific treatment. MATERIAL AND METHODS. We performed DISE under propofol sedation in 27 patients diagnosed with sleep apnea who addressed to our clinic for further investigation and treatment. We assessed the obstruction type and severity using the Fujita scale, VOTE (velum, oropharynx, tongue base, epiglottis) and NOHL (nose, oropharynx, hypopharynx, larynx). Finally, we correlated the DISE findings with the polysomnographic results. RESULTS. We observed significant correlations between the obstruction severity seen at DISE and the polysomnographic results. Further, we could decide the appropriate treatment for our patients, whether surgical or not (continuous positive airway pressure - CPAP). CONCLUSION. Sleep endoscopy represents a very important method in establishing the topographic diagnostic of sleep apnea patients, being useful for the therapeutic decision and the postoperative assessment. We recommend drug-induced sleep endoscopy as elective investigation regarding the diagnostic and treatment of sleep apnea patients.

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