Incidence and pattern of leukemia in Bhutanese population: a retrospective analysis of eight years (January 2008 to December 2015)

2016 ◽  
Vol 2 (2) ◽  
pp. 6-9
Author(s):  
Kuenzang Dorji ◽  
Krishna Prasad Sharma ◽  
Rinzin Jamtsho ◽  
Puja Devi Samal ◽  
Dorji Wangchuk ◽  
...  
Keyword(s):  
Risk Factors ◽  
Incidence Rate ◽  
Blood Cells ◽  
Statistical Significance ◽  
Descriptive Statistics ◽  
Haematological Malignancies ◽  
Female Ratio ◽  
Male To Female ◽  
National Referral Hospital

Introduction: The burden of haematological malignancies in developing countries is on the rise. This burden may be further aggravated in Bhutan due to the aging population and rapid modernization of the nation. Despite this, there is a paucity of information about the incidence and pattern of leukemia in the Bhutanese population. In this retrospective study, we aim to investigate the incidence and pattern of leukemia in Bhutan using a database of leukemia diagnosed at Jigme Dorji Wangchuck National Referral Hospital, Thimphu, Bhutan from January 2008 to December 2015. Methods: The diagnoses and classification of leukemias were based on the morphology of blood cells on peripheral blood and bone marrow smears. The data was analyzed with descriptive statistics. The age-standardized incidence rate per 100,000 populations and its 95% confidence interval was calculated to assess the statistical significance. Results: In total 118 patients were diagnosed with leukemia over the period of eight years. Leukemia was found to be more frequent in male (51.69%) compared to female (48.30%) with a male to female ratio of 1.1:1. Acute leukemia accounted for 66.95% of all leukemia case diagnosed, whereas chronic leukemia accounted for only 33.05% of the cases. The average, annual, age-standardized incidence rate of leukemia per 100,000 population was 2.30 (95% CI: 1.87-2.73). Conclusions: The incidence and pattern of leukemia in the Bhutanese population is similar to other published literature. Leukemia is not uncommon in the Bhutanese population, thus additional studies on risk factors for leukemia in the Bhutanese population is necessary.

scholarly journals Prevalence, Risk Factors, Awareness, and Treatment and Control of Hypertension in Mafia Island, Tanzania

2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
M. S. Muhamedhussein ◽  
Z. I. Nagri ◽  
K. P. Manji
Keyword(s):  
Risk Factors ◽  
South Africa ◽  
Health Education ◽  
Descriptive Statistics ◽  
Female Ratio ◽  
High Prevalence ◽  
Receive Treatment ◽  
And Control ◽  
Male To Female

Introduction. The prevalence of hypertension in Africa ranges from 29.7% in Cameroon to 47% in South Africa. Only 10% receive treatment in Cameroon while 32% are on medications in Ghana. Control rates vary from 0.4% to 16.8%. This study was done to assess prevalence, risk factors, awareness, treatment, and control of hypertension in Mafia Island, Tanzania, which has never been documented before, so that necessary interventions can be undertaken accordingly.Methodology. Data was collected through questionnaires and anthropometric measurements were taken. Descriptive statistics were done and potential correlations were analyzed.Results. Out of 570 adults who were included in the study, 154 (27%) were aged 41–50 and the male-to-female ratio was 1 : 1.05. Almost half (49.5%) of the participants fit into the criteria of hypertension. Out of the 118 participants who were aware of having hypertension, 68 (57.6%) were currently taking medication. From those taking medication, only 14 (20.6%) had controlled hypertension.Conclusion. This study tried to show the extent of hypertension and find out risk factors which could explain the high prevalence of hypertension. This is very alarming and a dire need to raise awareness through health education, availability of screening, and treating and follow-up should be given priority.

scholarly journals High rates of gastroesophageal cancers in patients with dyspepsia undergoing upper gastrointestinal endoscopy in Uganda

2021 ◽  
Vol 09 (07) ◽  
pp. E997-E1000
Author(s):  
Ronald Mbiine ◽  
Cephas Nakanwagi ◽  
Olivia Kituuka
Keyword(s):  
Positive Association ◽  
Referral Hospital ◽  
Outcome Variable ◽  
Mulago Hospital ◽  
Upper Gastrointestinal Endoscopy ◽  
Female Ratio ◽  
Mulago National Referral Hospital ◽  
Male To Female ◽  
Upper Gastrointestinal ◽  
National Referral Hospital

Abstract Background and study aims Dyspepsia is the most common presenting symptom in the gastrointestinal clinic of Mulago National Referral hospital. The etiology is essentially not fully described in our patient population. This study was therefore conducted to establish the causes of dyspepsia based on endoscopic diagnosis among patients with dyspepsia seeking care at the National Referral hospital of Uganda. Patients and methods This retrospective study conducted in the endoscopy unit of Mulago hospital reviewed 356 patient endoscopy reports spanning January 2018 to July 2020 with a focus on those with a referral indication of dyspepsia. Age and sex were the independent variables of interest while the endoscopy findings as reported by the endoscopist were the outcome variable of interest. Results Of the 356 endoscopy reports reviewed, 159 met the inclusion criterion of dyspepsia as the indication. Participant mean age was 47.7 years (± 16.53) with the majority (25.79 %) in the fifth decade while the male to female ratio was 1. The majority of patients had organic dyspepsia (90.57 %) while the commonest finding was gastritis 69 (43.4 %). Gastroesophageal cancers represented (18) 11.32 % of all findings. There was a positive association between age > 50 years with gastroesophageal cancers (7.639) as well as age < 50 years and functional dyspepsia (2.794); however, all these were not statistically significant (P = 0.006 and (P = 0.095, respectively). Conclusions Organic/structural dyspepsia comprises over 90 % of investigated dyspepsia with 11 % comprising cancer among patients seeking endoscopy at the National Referral Hospital of Uganda.

scholarly journals The Prevalence of Myeloproliferative Disorders in A Group of Iraqi Patients And Its Relation To Blood Indices Parameters

2020 ◽  
Vol 8 (A) ◽  
pp. 660-665
Author(s):  
Marwa Abdulnabi ◽  
Enass Abdul Kareem Dagher Al-Saadi
Keyword(s):  
Bone Marrow ◽  
Blood Cells ◽  
Myeloproliferative Neoplasms ◽  
Myeloproliferative Disorders ◽  
Myelogenous Leukemia ◽  
High Exposure ◽  
Female Ratio ◽  
Blood Samples ◽  
Blood Indices ◽  
Male To Female

AIM: The aim of this study was to measure the prevalence of myeloproliferative disorders in a sample of Iraqi patients and to measure the changes in patients’ blood parameters. BACKGROUND: Myeloproliferative disorders are a group of neoplasms affecting the bone marrow progenitor cells characterized by excess cells with a risk of transforming to acute leukemia. There is a gap in knowledge about the prevalence of Iraqi population. Thus, we investigated the prevalence and distribution of different types of myeloproliferative disorders in a sample of Iraqi patients. MATERIALS AND METHODS: Cross-sectional study is done at the National Center of Hematology from November 2019 till March 2020 on 75 patients who were diagnosed by a specialist hematopathologist to have one subtype of myeloproliferative disorders (MPDs). Blood samples were taken from them and analyzed to get complete blood count, blood film, bone marrow aspirate, and biopsy that were analyzed for each patient. Blood samples were taken from them and analyzed in terms of blood indices, which include red blood cells, white blood cells, and platelets. RESULTS: The 75 patients were found to be comprising 35 chronic myelogenous leukemia (CML) patients (46.7%), myelofibrosis 22 patients (29.3%), essential thrombocythemia (ET) 9 patients (12%), and polycythemia vera (PV) 9 patients (12%). In terms of male/female ratios, they were as follows: Myeloproliferative neoplasms (MPNs) male-to-female ratio is 1.2, CML= 0.94, myelofibrosis= 2.14 and ET= 0.5 and PV male-to-female ratio is 2. CONCLUSIONS : MPN male-to-female ratio in Iraq, which is 1.2, CML is the most common subtype. Regarding myelofibrosis, in our study, the male-to-female ratio is 2.14, which is much higher other countries. This could be attributed to high exposure to benzene and toluene which are well known to be causative agents for myelofibrosis. Regarding ET or PV, the male-to-female ratios were compatible with other countries.

scholarly journals The utility of ‘home-made’ reagent red blood cells for antibody screening during pre-transfusion compatibility testing in Uganda

2021 ◽  
Vol 21 (2) ◽  
pp. 782-787
Author(s):  
Bernard Natukunda ◽  
Robert Wagubi ◽  
Ivan Taremwa ◽  
Benson Okongo ◽  
Yona Mbalibulha ◽  
...  
Keyword(s):  
United States ◽  
Blood Cells ◽  
Current Practice ◽  
The United States ◽  
Extended Phenotype ◽  
Female Ratio ◽  
Fusion Safety ◽  
Indirect Antiglobulin Test ◽  
Antiglobulin Test ◽  
Male To Female

Background: The WHO recommends that pre-transfusion testing should include ABO/RhD grouping followed by screen- ing for red blood cell (RBC) alloantibodies using the indirect antiglobulin test (IAT). However, in Uganda, current practice does not include RBC alloantibody screening. Objective: To assess the utility of ‘home-made’ reagent RBCs in alloantibody screening. Materials and methods: In a laboratory-based study, group O RhD positive volunteer donors were recruited and their extended phenotype performed for C, c, E, e, K, Fya, Fyb Jkb, S and s antigens. These ‘home-made’ reagent RBCs were preserved using Alsever’s solution and alloantibody detection tests performed. For quality assurance, repeat alloantibody screening of patients’ samples was done at Bloodworks Northwest Laboratory in Seattle, United States. Results: A total of 36 group O RhD positive individuals were recruited as reagent RBC donors (median age, 25 years; range, 21 – 58 years; male-to-female ratio, 1.6:1). Out of the 311 IATs performed, 32 (10.3%) were positive. Confirmatory IAT testing in the United States was in agreement with the findings in Uganda. Conclusion: Use of ‘home-made’ reagent RBCs during pre-transfusion testing in Uganda is feasible. We recommend the introduction of pre-transfusion IAT alloantibody screening in Uganda using ‘home-made’ reagent RBCs to improve trans- fusion safety. Keywords: Blood transfusion; ‘Home-made’ reagent RBCs; Pre-transfusion testing; RBC alloantibody screening; Uganda.

Asthma in the Critically Ill Patient

2019 ◽  
pp. 150-156
Author(s):  
Jonathan J. Danaraj ◽  
Augustine S. Lee
Keyword(s):  
United States ◽  
Risk Factors ◽  
Immunoglobulin E ◽  
Age Distribution ◽  
The United States ◽  
Critically Ill Patient ◽  
Common Condition ◽  
Female Ratio ◽  
Genetic And Environmental Factors ◽  
Male To Female

Asthma is a common condition that affects an estimated 24 million children and adults in the United States (prevalence, 8%-10%). Globally, over 300 million people are affected and the number is expected to increase. The age distribution is bimodal, but in most patients, asthma is diagnosed before age 18 years (male to female ratio, 2:1 in children; 1:1 in adults). Susceptibility to asthma is multifactorial with both genetic and environmental factors. The strongest risk factor is atopy, a sensitivity to the development of immunoglobulin E (IgE) to specific allergens. A person with atopy is 3- to 4-fold more likely to have asthma than a person without atopy. Other risk factors include birth weight, prematurity, tobacco use (including secondary exposure), and obesity.

scholarly journals Risk factors for open conversion of laparoscopic biliary surgery

2018 ◽  
Vol 5 (3) ◽  
pp. 846
Author(s):  
Asem F. Mohammed ◽  
Moharm A. Abdelshahid ◽  
Mohammed A. Elbalshy
Keyword(s):  
Risk Factors ◽  
Open Approach ◽  
Surgical Experience ◽  
University Hospitals ◽  
Biliary Surgery ◽  
Female Ratio ◽  
Open Conversion ◽  
Conversion Rates ◽  
Co Morbidity ◽  
Male To Female

Background: Conversion rates of laparoscopic to open biliary procedures vary according to different factors such as clinical presentation, co-morbidity, surgical experience and equipment.Methods: A prospective analysis of 464 laparoscopic cholecystectomies (LC) including 88 laparoscopic common bile duct explorations (LCBDE) over a period of 5 years was carried out in Menofia University Hospitals, between December 2012 to December 2017.Results: The male to female ratio in the series was 1:3.4 with a Median±SD age 51±16 years.  158 cases (34%) of all patients were admitted as an emergency including jaundice in 60 cases (13%), acute pancreatitis in 27 cases 6% and acute cholecystitis/empyema in 27 cases (6%). 153 cases (33%) had previous abdominal surgery. LCBDE was done in 88 cases. open conversion was necessary in 6/464 cases (1.3%) over 5 years; with no conversions in the last 2 years (130 cases). converted cases had a Median±SD age 53±17 years and 67% were female.Conclusions: Several risk factors favour conversion from laparoscopic to an open approach in biliary surgeries that has to be identified preoperative to provide a better surgery.

scholarly journals Dor crônica avaliada pela Classificação dos Resultados de Enfermagem

2020 ◽  
Vol 14 ◽  
Author(s):  
Cássia Teixeira Dos Santos ◽  
Claudenilson Da Costa Régis ◽  
Raquel Silveira Einhardt ◽  
Amália De Fátima Lucena
Keyword(s):  
Chronic Pain ◽  
Statistical Significance ◽  
Descriptive Statistics ◽  
Nursing Interventions ◽  
Test Results ◽  
Nursing Process ◽  
Nursing Outcomes ◽  
Nursing Outcomes Classification ◽  
Student Test

Objetivo: analisar resultados e indicadores de enfermagem da Nursing Outcomes Classification/NOC (Classificação dos Resultados de Enfermagem) na avaliação de pacientes com dor crônica em consulta de enfermagem ambulatorial. Método: estudo quantitativo, longitudinal, prospectivo, com nove pacientes, por meio de instrumento contendo resultados e indicadores da NOC. Analisaram-se os dados pela estatística descritiva com uso do teste t-Student. Resultados: foram avaliados nove pacientes com idade média de 56,0 ± 18,2 anos, sexo feminino (88,9 %), brancos (66,7%) e afastados do trabalho (66%) pela Dor Crônica. Cinco resultados e 11 indicadores foram aplicados, o Controle da Dor apresentou dois indicadores com significância estatística. O Nível de Dor apresentou melhora nos escores de dois indicadores, e o Satisfação do Cliente manteve escores altos. Conclusão: os resultados de enfermagem e indicadores demonstraram melhora clínica dos pacientes com dor crônica na avaliação em consulta de enfermagem ambulatorial. Descritores: Avaliação de Resultados (Cuidados em Saúde); Dor crônica; Terminologia Padronizada em Enfermagem; Processo de Enfermagem; Enfermagem; Classificação.AbstractObjective: to analyze nursing results and indicators from the Nursing Outcomes Classification/NOC (Classification of the Results of Nursing Interventions) in the evaluation of patients with chronic pain in an outpatient nursing consultation. Method: a quantitative, longitudinal, prospective study with nine patients, using an instrument containing NOC results and indicators. Data were analyzed using descriptive statistics using the t-Student test. Results: nine patients with a mean age of 56.0 ± 18.2 years, female (88.9%), white (66.7%) on authorized sick leave (66%) due to chronic pain were evaluated. Five results and 11 indicators were applied, the Pain Control presented two indicators with statistical significance. The Pain Level improved in the scores of two indicators, and Customer Satisfaction maintained high scores. Conclusion: the nursing results and indicators showed clinical improvement of patients with chronic pain in the evaluation at an outpatient nursing consultation. Descriptors: Outcome Assessment (Health Care); Chronic pain; Standardized Nursing Terminology; Nursing Process; Nursing; Classification.ResumenObjetivo: analizar los resultados e indicadores de enfermería de la Nursing Outcomes Classification/NOC (Clasificación de los resultados de enfermería) en la evaluación de pacientes con dolor crónico en una consulta de enfermería ambulatoria. Método: estudio cuantitativo, longitudinal, prospectivo con nueve pacientes, utilizando un instrumento que contiene resultados e indicadores de NOC. Los datos se analizaron mediante estadística descriptiva utilizando la prueba t-Student. Resultados: se evaluaron nueve pacientes con una edad media de 56.0 ± 18.2 años, mujeres (88.9%), blancos (66.7%) y fuera del trabajo (66%) debido a dolor crónico. Se aplicaron cinco resultados y 11 indicadores, el Control del Dolor presentó dos indicadores con significación estadística. El nivel de dolor mejoró en los puntajes de dos indicadores, y la satisfacción del cliente mantuvo puntajes altos. Conclusión: los resultados de enfermería e indicadores  mostraron una mejoría clínica de pacientes con dolor crónico en la evaluación en una consulta de enfermería ambulatoria. Descriptores: Evaluación de Resultados (Atención de la Salud); Dolor crónico; Terminología de enfermería estandarizada; Proceso de enfermería; Enfermería; Clasificación.

scholarly journals Correlation of patient's mental attitude with age, sex, and educational level: A survey

2016 ◽  
Vol 10 (01) ◽  
pp. 023-028 ◽  
Author(s):  
Shweta Choudhary ◽  
Ajit Kumar ◽  
Himanshu Arora
Keyword(s):  
College Graduates ◽  
Age Groups ◽  
Educational Status ◽  
Age Group ◽  
Oral Rehabilitation ◽  
Mental Attitude ◽  
Female Ratio ◽  
Patient Cooperation ◽  
Male To Female

ABSTRACT Objective: The aim of this study was to determine any relationship, if exists, between the patient's mental attitude with age, sex, or educational qualification. Methods: A total of 200 patients who attended the outpatient department during a span of 1 year, for the fabrication of new complete dentures, were chosen for the study. After completing a routine case history and examination, a questionnaire was filled by the clinician as answered by the patient. Participants were evaluated and categorized based on the questionnaire and clinical experience during treatment according to a predefined classification of determining mental attitudes. Outcomes from the survey were correlated with participant gender, age, and educational status. Results: The male to female ratio was 83:117, out of the 200 enrolled participants. The results from the questionnaire showed that females were found to be more exacting (P = 0.007) in nature, while males, on the other hand, revealed more indifferent attitude (P = 0.02); both differences being statistically significant. Of the three age group categories: Participants in the age group of 45–54 years revealed a significant inclination toward an exacting attitude when compared with other age groups (P < 0.001). In regards to educational status, an illiterate or minimally educated group significantly outnumbered the college graduates in the indifferent attitude group (P < 0.001). Conclusions: Within the limitations of this study, it could be said that the mental attitudes of patients could vary according to gender, age, and educational status, which could affect patient cooperation and satisfaction with oral rehabilitation, eventually manipulating the overall success of the treatment rendered.

scholarly journals Geographical distribution of the associated factors of osteonecrosis of the femoral head, using the designated intractable disease database in Japan

2021 ◽  
Author(s):  
Wataru Ando ◽  
Masaki Takao ◽  
Tetsuro Tani ◽  
Keisuke Uemura ◽  
Hidetoshi Hamada ◽  
...  
Keyword(s):  
Risk Factors ◽  
Femoral Head ◽  
Age Distribution ◽  
Female Ratio ◽  
Registry System ◽  
Registration Rate ◽  
The Mean ◽  
Associated Risk Factors ◽  
Epidemiological Characteristics ◽  
Male To Female

ABSTRACT Objectives Osteonecrosis of the femoral head (ONFH) is a designated intractable disease (DID) in Japan. The Ministry of Health, Labour, and Welfare launched an online registry system for DIDs. We aimed to investigate the epidemiological characteristics of patients with ONFH using the DID database. Methods Data of patients with ONFH registered in the DID database between January 2004 and December 2013 were extracted. The incidence of new cases and distributions of sex, age, and associated risk factors were investigated. The prevalence of the two categories, ‘steroid-associated’ and ‘alcohol-associated’ risk factors, was estimated for each prefecture. Results New 15,049 cases of ONFH were investigated. The mean registration rate-corrected annual ONFH incidence per 100,000 individuals was 1.77. The male-to-female ratio was 1.33. Age distribution peaked in the 40s and 50s for male and 60s for female. The prevalence of steroid-associated ONFH was lower in males (28.6%) than in females (49.8%), while that of alcohol-associated ONFH was higher in males (47.2%) than in females (9.3%). No clear region was identified for the steroids. The incidence of alcohol-associated ONFH was significantly higher in Tokyo and Okinawa, regardless of sex. Conclusions Alcohol-associated ONFH incidence varies geographically across Japan, suggesting that it has regional characteristics.

scholarly journals Profile of refractive error in Ekiti, south western Nigeria

2018 ◽  
Vol 77 (1) ◽  
Author(s):  
Iyiade A. Ajayi ◽  
Olusola J. Omotoye ◽  
Olubunmi Omotoso-Olagoke
Keyword(s):  
Refractive Error ◽  
Allergic Conjunctivitis ◽  
Statistical Significance ◽  
Refractive Errors ◽  
Southwestern Nigeria ◽  
Female Ratio ◽  
Eye Disorders ◽  
Ocular Disorders ◽  
The Mean ◽  
Male To Female

Background: Refractive error is one of the eye disorders with the capability of causing visual impairment. We needed to know the various types and proportion of refractive errors seen in patients attending an eye clinic at the tertiary health centre.Aim: An observational study was carried out to determine the profile of refractive error in a southwestern Nigeria hospital.Methods: All new cases with the diagnosis of refractive error between January 2015 and December 2016 had autorefraction and subjective refraction to determine the types and values of refractive error. Data were analysed with SPSS 20. Statistical significance was inferred at p < 0.05.Results: Refractive error constituted 618 (21.4%) of the total new cases. The mean age was 39.3 ± 22.96 years. The male to female ratio was 1:1.8. Children constituted 25.7% of all the cases. The most common refractive error was myopia in 64.3%. A total of 312 (50.5%) patients had other co-existing ocular disorders with allergic conjunctivitis on the top of the list. The number of visually impaired reduced to 70 (5.64%) after the correction of existing refractive error with about 94.1% having their visual acuity restored to normal.Conclusion: Refractive error was a common eye disorder among our patients with the proportion of children about a quarter of all patients. We recommend that childhood refractive errors should be given prioritised attention in eye outreach programmes.

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