scholarly journals Aquaporin 4 antibody–negative neuromyelitis optica spectrum disorder (NMOSD) associated with Sjogren's Syndrome

2021 ◽  
Author(s):  
Matheus Silva Koike ◽  
André Silva Franco ◽  
Isabele Parente de Brito Antonelli ◽  
Guilherme Guimarães Moreira Balbi ◽  
Karina Fernanda Pucha Aguinsaca ◽  
...  
Keyword(s):  
Sjögren’S Syndrome ◽  
Neuromyelitis Optica ◽  
Sjögren's Syndrome ◽  
Sjogren’S Syndrome ◽  
Sjogren's Syndrome ◽  
Spectrum Disorder ◽  
Aquaporin 4 ◽  
Neuromyelitis Optica Spectrum Disorder ◽  
Aquaporin 4 Antibody ◽  
Sjögren‘S Syndrome

scholarly journals A Rare Case of Neuromyelitis Optica Spectrum Disorder in Patient with Sjogren’s Syndrome

2014 ◽  
Vol 2014 ◽  
pp. 1-3 ◽  
Author(s):  
Supat Thongpooswan ◽  
Bikash Chapagain ◽  
Sabiha Bandagi
Keyword(s):  
Sjögren’S Syndrome ◽  
Neuromyelitis Optica ◽  
Sjögren's Syndrome ◽  
Oral Prednisone ◽  
Sjogren’S Syndrome ◽  
Sjogren's Syndrome ◽  
Spectrum Disorder ◽  
Neuromyelitis Optica Spectrum Disorder ◽  
History Of ◽  
Sjögren‘S Syndrome

We report a 48-year-old female with the history of Sjogren’s syndrome who presented with 3-week history of tingling, numbness, and shooting back, waist, and bilateral leg pain and numbness in the pelvic region with urinary and bowel incontinence. Physical examination was remarkable for reduced motor power in both lower extremities with spasticity. Sensory deficit was noted at the T6 level. Laboratory investigation revealed elevated ESR and CRP and positive serum antiaquaporin-4 IgG. Thoracic and lumbar magnetic resonance imaging revealed abnormal patchy areas, leptomeningeal enhancement through the thoracic cord extending from T3 through T6 levels, without evidence of cord compression. Impression of neuromyelitis optica spectrum disorder was made and patient was treated with methylprednisolone intravenously followed by tapering oral prednisone. Neurological symptoms gradually improved with resolution of bowel and urinary incontinence. In a patient with Sjogren’s syndrome who presents with neurological complaints, the possibility of neuromyelitis optica or neuromyelitis optica spectrum disorder should be considered. Awareness of the possibility of CNS disease is important due to the serious nature of CNS complications, some of which are treatable with immunosuppressants. Our patient with Sjogren’s syndrome who presented with myelopathy benefited from early recognition and institution of appropriate therapy.

scholarly journals SJÖGREN'S SYNDROME AND NEUROMYELITIS OPTICA SPECTRUM DISORDER: CASE REPORT

2021 ◽  
Author(s):  
Aurivan Essado Dantas ◽  
Camila Gabriela Xavier de Brito ◽  
Ana Luisa Bagno de Almeida ◽  
Matheus Fonseca Cardoso ◽  
Larissa Maria Oliveira Gonzaga ◽  
...  
Keyword(s):  
Case Report ◽  
Sjögren’S Syndrome ◽  
Neuromyelitis Optica ◽  
Sjögren's Syndrome ◽  
Sjogren’S Syndrome ◽  
Sjogren's Syndrome ◽  
Spectrum Disorder ◽  
Neuromyelitis Optica Spectrum Disorder ◽  
Sjögren‘S Syndrome
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