Correlation between glycaemic state and tooth mobility in periodontal patients

Author(s):  
Quratulain Saeed ◽  
Sarwat Memon ◽  
Mervyn Hosein ◽  
Aswad Ahmed ◽  
Sana Ikram

Objective: To evaluate the association of tooth mobility with blood glucose levels and control in patients with periodontitisMethodology: The study was conducted at the department of Oral Medicine, Ziauddin Dental Hospital, Karachi. The study design was cross-sectional. The duration of this study was of 6 months, between December 2018 and May 2019. The study population involved 348 patients with chronic periodontitis. After recording demographic details and dental charting, tooth mobility scores were correlated with gingival crevicular blood glucose, finger capillary blood glucose and glycosylated hemoglobin levels by Pearson’s correlation. Linear regression was applied to assess the inter-relation between variables.Results: The mean age of individuals who participated in this study was 43+/-10.4 years. The average number of teeth present in patients with glucose levels <180mg/dl was 25.5+/-2.5 compared to 23.2+/-2.9 in individuals with glucose values of >200mg/dl. A moderate positive correlation (r=0.658) was seen between gingival crevicular blood glucose levels and tooth mobility. Finger capillary blood glucose levels also showed good correlation (R=0.653) with tooth mobility scores. HbA1c scores showed a strong positive correlation(R=0.733). Linear regression confirmed increased HbA1c as a risk factor for tooth mobility (R2=0.524, p value= 0.000).Conclusion: Tooth mobility and glycaemic levels are strongly interrelated. This study provides evidence that poor glycaemic control may contribute to the etiology of tooth mobility in patients with periodontitis. Continuous...

2017 ◽  
Vol 13 (5) ◽  
pp. 433-438 ◽  
Author(s):  
Tatiana Smolkin ◽  
Irena Ulanovsky ◽  
Pnina Carasso ◽  
Imad R. Makhoul

Author(s):  
Suresha R. N. ◽  
Siddamma Amoghimath ◽  
Jayanthi M. K.

Background: Diabetes mellitus (DM) consists of a group of syndromes characterised by hyperglycaemia, altered metabolism of lipids, carbohydrates and proteins and an increased risk of complications from vascular disease. There are genetic and environmental components that affect the risk of developing either type 1 or type 2 diabetes mellitus.Methods: Twelve Swiss albino rats weighing around 150-200gmsof either sex were randomly selected from the central animal facility, JSSMC, Mysore and divided into two groups. The control group received distilled water (25ml/kg body wt.) per orally, test group received Neostigmine (0.5mg/kg/day) per orally for 5 days. On the fifth day, following overnight fasting, 1 hour after drug administration in all the group of rats OGTT was performed, by administering oral glucose in dose of 0.6gm/kg body weight. The capillary blood glucose level was measured at 0, 60 and 150 minutes, by rat tail snipping method using (ACCUCHEK) glucometer.Results: The Capillary Blood Glucose levels of Neostigmine group was less when compared to control group at all-time intervals.Conclusions: Neostigmine showed the hypoglycemic activity when given for 5 days orally in euglycemic albino rats through OGTT.


Diabetologia ◽  
1980 ◽  
Vol 19 (1) ◽  
pp. 31-34 ◽  
Author(s):  
R. B. Paisey ◽  
D. G. Macfarlane ◽  
R. J. Sherriff ◽  
M. Hartog ◽  
R. R. Slade ◽  
...  

Heliyon ◽  
2019 ◽  
Vol 5 (3) ◽  
pp. e01286 ◽  
Author(s):  
Richard K.D. Ephraim ◽  
Enoch Odame Anto ◽  
Emmanuel Acheampong ◽  
Linda Ahenkorah Fondjo ◽  
Richmond B. Barnie ◽  
...  

2009 ◽  
Vol 10 (2) ◽  
pp. 10-17 ◽  
Author(s):  
Amir Moeintaghavi ◽  
Mohammad Reza Talebi Ardakani ◽  
Ahmad Haerian ◽  
Mohammad Afkhami Ardakani ◽  
Mahdi Hashemzadeh

Abstract Aim The aim of this study was to evaluate the correlation between capillary blood glucose levels (CBGLs) and sulcular blood glucose levels (SBGLs) using blood obtained from gingival tissue during routine periodontal examinations to determine if sulcular blood samples can be used as a non-invasive means to diagnosis blood glucose levels. Methods and Materials Thirty non-diabetics and 30 diabetic patients with moderate to severe periodontitis were included in the study and subjected to routine clinical periodontal examinations. Blood was collected using a 1.6-1.8 mm diameter micro bite collection tube to transport the sample from the gingival sulci of anterior teeth following periodontal pocket probing to a test strip of a glucose self-monitoring device. As a control, capillary blood was taken with a finger-stick. Statistical analysis was performed using the Pearson's correlation coefficient and a t-test. Results The blood glucose levels in patients ranged from 58 mg/dl to 477 mg/dl, and the values of blood samples taken from gingival sulcus or finger tip of the same patient showed a very high intra-patient correlation (r =0.99, p< 0.0001). Conclusion The results of this study suggest sulcular blood from a routine periodontal examination may be used for diabetes mellitus screening. Clinical Significance Considering 50% of diabetics remain undiagnosed, testing sulcular blood may provide a suitable method for identifying potential diabetic patients during routine dental visits since there is a correlation with capillary blood. Appropriate referrals to a physician can then be made when warranted. Citation Ardakani MRT, Moeintaghavi A, Haerian A, Ardakani MA, Hashemzadeh M. Correlation between Levels of Sulcular and Capillary Blood Glucose. J Contemp Dent Pract 2009 March; (10)2:010-017.


2018 ◽  
Vol 5 (1) ◽  
pp. 33-38 ◽  
Author(s):  
Md Khairuzzaman ◽  
Nihar Ranjan Sarker ◽  
Mst Monjuman Ara Sarker ◽  
Abdul Matin ◽  
Sudesh Chandra Rakshit ◽  
...  

Background: Transient hypoglycemia in the early neonatal period is a common adaptive phenomenon as the newborn changes from the fetal state of continuous transplacental glucose consumption to intermittent nutrient supply following cessation of maternal nutrition at birth. This adaptation is well established in term appropriate for gestational age babies but is not established in low birth weight babies. Objective: this study was undertaken to evaluate glycemic status of the low birth weight babies and impact of early feeding.Methodology: This prospective observational study was done in the department of Pediatrics and department of obstetrics, Rangpur Medical College Hospital, Rangpur, Bangladesh from September 2005 to February 2006 for a period of six (6) months. Blood sugar was estimated at birth (cord blood) and then from capillary blood at 2 hours, 4 hours, in between 12 to 24 hours and in between 24 to 48 hours. The capillary blood was obtained by heel prick. Venous sample was sent to the college laboratory for confirmation if the blood sugar was less than 2.6 mmol/L (47 mg/dL). Result: In the first 48 hours, the blood glucose levels were lowest at 2 hours after delivery and the level gradually increased with increasing postnatal age in low birth weight babies. Birth weight had a positive correlation with blood glucose levels of low birth weight babies. The overall incidence of hypoglycemia in low birth weight babies were 31.8%, among them 77.1% asymptomatic and 22.9% symptomatic. The mean blood glucose levels were significantly high in early feed group than the delayed feed group babies (p<0.05).Conclusion: The blood glucose levels is lowest at 2 hours after delivery and the level gradually increases with increasing postnatal age in low birth weight babies which is a positive correlation with blood glucose levels of low birth weight babies.Journal of Current and Advance Medical Research 2018;5(1):33-38


2019 ◽  
Vol 6 (4) ◽  
pp. 1220
Author(s):  
Uma Maheswara R. Golamari ◽  
Meenakshi Sundari Subramaniyan Natarajan ◽  
Annam Lakshmanan ◽  
Rajeswari K. Balakrishnan

Background:  The aim of this study was to determine as well as to compare the salivary glucose levels in the diabetic and non-diabetic population and correlate the values with their fasting blood glucose and HbA1c (glycated Haemoglobin) levels. Many researchers have proposed the possibility of using salivary glucose estimation for screening and monitoring of effect in general population and in resource poor settings. But studies on this subject in Indian population are limited.Methods: The current study was an analytical cross sectional study of a group of 100 diabetic patients and 100 healthy controls, conducted in the Department of General Medicine, SRM medical college hospital. The mean difference in the salivary glucose between diabetic and non-diabetic population was compared using unpaired t-test.Results: There was a strong positive association between FBS (fasting blood sugar) and salivary glucose in the overall population. There was a strong positive correlation between FBS and Salivary glucose in FBS <200. There was a moderate positive association between FBS and salivary glucose in people with FBS value between 200 to 300 mg/dl. There was a weak positive association between FBS and salivary glucose in people with FBS value >300 mg/dl, which was statistically not significant. There was a strong positive correlation between HbA1c and salivary glucose in the overall population.Conclusions: There appears to be a strong positive association between fasting blood sugar and salivary glucose value in both study groups. But the correlation seems to be relatively weak in fasting blood sugar range above 300 mg/dl. Considering this positive association, further studies are needed to explore the possibility of utilizing salivary glucose for monitoring glycemic control.


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