scholarly journals Everolimus-eluting bioresorbablecoronary scaffold in Asian patients; a 2-yearfollow-up

Author(s):  
Muhammad Abdul Salam Azad ◽  
Uzma Gul ◽  
Asim Javed

Abstract Indo-Pakistan population has one of the highest risk of coronary artery disease(CAD) in the world.1Percutaneous interventions with the use of stents has been the mainstay of treatment for CAD, evolving from balloon angioplasty to bare metal stents and then to drug eluting stents. However, there are a few drawbacks related to the metal implant in the coronary, leading to the development of bio-resorbable vascular scaffolds(BVS). This case series studies the implantation techniques and 24 month clinical outcome of bioresorbable stent Absorb at Rawalpindi Institute of Cardiology. From November 1, 2013 till June 30, 2018. Fifty patients undergoing angioplasty with Absorb BVS as elective or primary PCI were enrolled. Case selection was at the discretion of the operator. Patients were followed up clinically. Repeat angiogram was conducted if clinically indicated.  Continuous...  

2019 ◽  
Vol 9 (17) ◽  
pp. 3527 ◽  
Author(s):  
Alexandre Hideo-Kajita ◽  
Samuel Wopperer ◽  
Vinícius Bocchino Seleme ◽  
Marcelo Harada Ribeiro ◽  
Carlos M. Campos

In the treatment of atherosclerotic disease patients, the adoption of second-generation drug-eluting stents (DES) in percutaneous coronary intervention reduced the occurrence of in-stent restenosis (ISR) and acute stent thrombosis (ST) when compared to bare metal stents and 1st generation DES. However, the permanent encaging of the vessel wall by any of the metallic stents perpetuates the inflammation process and prevents vasomotion in the treated segment. Aiming to overcome this issue, the bioresorbable scaffold (BRS) concept was developed by providing transient vascular radial support to the target segment during the necessary time to heal and disappearing after a period of time. Close to 20 years since BRS technology was first reported, the interventional cardiology field saw the rise and fall of several BRS devices. Although iron-based BRS is an emerging technology, currently, magnesium-alloy resorbable scaffolds devices are supported with the most robust data. This manuscript aims to review the concept of magnesium-based BRS devices, as well as their bioresorption mechanisms and the status of this technology, and the clinical outcomes of patients treated with magnesium BRS and to review the available evidence on iron-based BRS technology.


Praxis ◽  
2017 ◽  
Vol 106 (2) ◽  
pp. 85-89
Author(s):  
Zaid Sabti ◽  
Raban Jeger

Zusammenfassung. Die perkutane Ballonangioplastie revolutionierte die Behandlung der koronaren Herzkrankheit. Der Einsatz von Gefässstützen (Stents) setzte diese Revolution fort. Nach den reinen Metallstents (Bare metal stents, BMS) und den Medikamenten-beschichteten Stents (drug-eluting stents, DES) folgen nun bioresorbierbare Stents (bioresorbable vascular scaffolds, BVS). Im Gegensatz zu den ersten zwei Stent-Generationen werden die BVS nach einer bestimmten Zeit vollständig abgebaut und versprechen eine Antwort für bisher ungelöste Probleme von BMS und DES.


2014 ◽  
Vol 6 (2) ◽  
pp. 149-163 ◽  
Author(s):  
M Ullah ◽  
AKMM Islam ◽  
AAS Majumer

Since the advent of percutaneous coronary angioplasty in 1977, immense experiment has been done to improve the outcome of the patients with coronary artery disease. Lot of trials have been done with angioplasty, bare metal stents, drug eluting stents, drug eluting balloons and other devices. Bioabsorbable vascular stents are relatively newcomers in this field with a lot of hope. We tried to update the latest status of Bioabsorbable vascular stents in this review, specially the short and midterm safety and efficacy and some of their limitations. DOI: http://dx.doi.org/10.3329/cardio.v6i2.18359 Cardiovasc. j. 2014; 6(2): 149-163


2016 ◽  
Vol 79 (12) ◽  
pp. 642-648 ◽  
Author(s):  
Wei-Ting Wang ◽  
Shih-Hsien Sung ◽  
Cheng-Hsueh Wu ◽  
Shao-Sung Huang ◽  
Wan-Leong Chen ◽  
...  

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