scholarly journals Progression of peripheral nerve injury in leprosy: Evaluation of the effect of nerve decompression surgery in an endemic region of Brazil

2021 ◽  
Vol 92 (2) ◽  
pp. 102-113
Author(s):  
Maria Dias Torres Kenedi ◽  
Elifaz de Freitas Cabral ◽  
Kazue Narahashi ◽  
Silvana Teixeira de Miranda ◽  
Catarina Mabel da Cunha Moreira ◽  
...  
Keyword(s):  
Peripheral Nerve ◽  
Nerve Injury ◽  
Peripheral Nerve Injury ◽  
Decompression Surgery ◽  
Endemic Region ◽  
Nerve Decompression ◽  
Nerve Decompression Surgery

Localised hypertrophic mononeuropathy (LHM) as a complication of peripheral nerve decompression surgery

2010 ◽  
Vol 112 (10) ◽  
pp. 921-923
Author(s):  
Esther S.T. Ng ◽  
Ter Chyan Tan ◽  
Aravind K. Therimadasamy ◽  
Einar Wilder-Smith
Keyword(s):  
Peripheral Nerve ◽  
Decompression Surgery ◽  
Nerve Decompression ◽  
Nerve Decompression Surgery

Transplantation Strategies for Spinal Cord Injury Based on Microenvironment Modulation

2020 ◽  
Vol 15 (6) ◽  
pp. 522-530
Author(s):  
Jiawei Shu ◽  
Feng Cheng ◽  
Zhe Gong ◽  
Liwei Ying ◽  
Chenggui Wang ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Peripheral Nerve ◽  
Nerve Injury ◽  
Autonomic Dysfunction ◽  
Peripheral Nerve Injury ◽  
Therapeutic Effects ◽  
Permanent Damage ◽  
Cord Injury ◽  
Severe Motor

Spinal cord injury (SCI) is different from peripheral nerve injury; it results in devastating and permanent damage to the spine, leading to severe motor, sensory and autonomic dysfunction. SCI produces a complex microenvironment that can result in hemorrhage, inflammation and scar formation. Not only does it significantly limit regeneration, but it also challenges a multitude of transplantation strategies. In order to promote regeneration, researchers have recently begun to focus their attention on strategies that manipulate the complicated microenvironment produced by SCI. And some have achieved great therapeutic effects. Hence, reconstructing an appropriate microenvironment after transplantation could be a potential therapeutic solution for SCI. In this review, first, we aim to summarize the influential compositions of the microenvironment and their different effects on regeneration. Second, we highlight recent research that used various transplantation strategies to modulate different microenvironments produced by SCI in order to improve regeneration. Finally, we discuss future transplantation strategies regarding SCI.

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