scholarly journals Positron Emission Mammography (PEM) in the diagnosis of breast cancer: A systematic review and economic evaluation

2020 ◽  
Author(s):  
Khosro Keshavarz ◽  
Mojtaba Jafari ◽  
Farhad Lotfi ◽  
Peivand Bastani ◽  
Mahmood Salesi ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Systematic Review ◽  
Economic Evaluation ◽  
Positron Emission Mammography ◽  
Positron Emission

Positron emission mammography in the diagnosis of breast cancer

2016 ◽  
Vol 55 (01) ◽  
pp. 15-20 ◽  
Author(s):  
J. Farahati ◽  
A. G. Müller ◽  
E. Gillman ◽  
M. Hentschel ◽  
F. H. H. Müller
Keyword(s):  
Breast Cancer ◽  
High Specificity ◽  
Diagnostic Value ◽  
Glandular Tissue ◽  
Breast Cancer Patients ◽  
Malignant Tumours ◽  
Benign Lesions ◽  
Interventional Study ◽  
Positron Emission Mammography ◽  
Positron Emission

SummaryAim: To evaluate the diagnostic value (sensitivity, specificity) of positron emission mammography (PEM) in a single site non-interventional study using the maximum PEM uptake value (PUVmax). Patients, methods: In a singlesite, non-interventional study, 108 patients (107 women, 1 man) with a total of 151 suspected lesions were scanned with a PEM Flex Solo II (Naviscan) at 90 min p.i. with 3.5 MBq 18F-FDG per kg of body weight. In this ROI(region of interest)-based analysis, maximum PEM uptake value (PUV) was determined in lesions, tumours (PUVmaxtumour), benign lesions (PUVmaxnormal breast) and also in healthy tissues on the contralateral side (PUVmaxcontralateral breast). These values were compared and contrasted. In addition, the ratios of PUVmaxtumour / PUVmaxcontralateral breast and PUVmaxnormal breast / PUVmaxcontralateral breast were compared. The image data were interpreted independently by two experienced nuclear medicine physicians and compared with histology in cases of suspected carcinoma. Results: Based on a criteria of PUV>1.9, 31 out of 151 lesions in the patient cohort were found to be malignant (21%). A mean PUVmaxtumour of 3.78 ± 2.47 was identified in malignant tumours, while a mean PUVmaxnormal breast of 1.17 ± 0.37 was reported in the glandular tissue of the healthy breast, with the difference being statistically significant (p < 0.001). Similarly, the mean ratio between tumour and healthy glandular tissue in breast cancer patients (3.15 ± 1.58) was found to be significantly higher than the ratio for benign lesions (1.17 ± 0.41, p < 0.001). Conclusion: PEM is capable of differentiating breast tumours from benign lesions with 100% sensitivity along with a high specificity of 96%, when a threshold of PUVmax >1.9 is applied.

The potential role of positron emission mammography for detection of breast cancer. A phantom study

2000 ◽  
Vol 27 (8) ◽  
pp. 1943-1954 ◽  
Author(s):  
Raymond R. Raylman ◽  
Stan Majewski ◽  
Randy Wojcik ◽  
Andrew G. Weisenberger ◽  
Brian Kross ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Potential Role ◽  
Phantom Study ◽  
Positron Emission Mammography ◽  
Positron Emission

Comparative Effectiveness of Positron Emission Mammography and MRI in the Contralateral Breast of Women With Newly Diagnosed Breast Cancer

2012 ◽  
Vol 198 (1) ◽  
pp. 219-232 ◽  
Author(s):  
Wendie A. Berg ◽  
Kathleen S. Madsen ◽  
Kathy Schilling ◽  
Marie Tartar ◽  
Etta D. Pisano ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Comparative Effectiveness ◽  
Contralateral Breast ◽  
Newly Diagnosed ◽  
Positron Emission Mammography ◽  
Positron Emission

scholarly journals Hormonal therapies for early breast cancer: systematic review and economic evaluation

2007 ◽  
Vol 11 (26) ◽  
Author(s):  
D Hind ◽  
S Ward ◽  
E De Nigris ◽  
E Simpson ◽  
C Carroll ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Systematic Review ◽  
Economic Evaluation ◽  
Early Breast Cancer ◽  
Hormonal Therapies

Evaluation of the Response to Breast Cancer Neoadjuvant Chemotherapy Using 18F-FDG Positron Emission Mammography Compared With Whole-Body 18F-FDG PET

2017 ◽  
Vol 42 (3) ◽  
pp. 169-175 ◽  
Author(s):  
Mutsumi Noritake ◽  
Kazutaka Narui ◽  
Tomohiro Kaneta ◽  
Sadatoshi Sugae ◽  
Kentaro Sakamaki ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Neoadjuvant Chemotherapy ◽  
Fdg Pet ◽  
Whole Body ◽  
Positron Emission Mammography ◽  
Positron Emission ◽  
18F Fdg
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