Effects of Structured lifestyle Modification on Cardiovascular Risk Factors in Type-2 Diabetes Mellitus: A Randomized Controlled Trial

2021 ◽  
Vol 4 (2) ◽  
pp. 27-36
Author(s):  
NM Lamu ◽  
SL Pitmang ◽  
DJ Meshak ◽  
NT Ishaya ◽  
J Anejo-Okopi ◽  
...  

Several clinical trials have shown that lifestyle modifications lower blood pressure, affect weight as well as lipid profile and lower risk factors for cardiovascular diseases. The study assessed the effect of structured lifestyle modification on cardiovascular risk factors amongst type 2 diabetic patients that attend the General Outpatient Clinic (GOPC) of Jos University Teaching Hospital (JUTH). The study was a randomized controlled trial on 352 participants at the GOPC of JUTH, from October 2015 to February 2016. The intervention offered was counselling on structured lifestyle modification in diet and exercise for a period of 12 weeks. The primary outcome measures were changes in blood pressure, weight and lipid profile. The data were analyzed using Epi Info version 3.5.3. There were significant differences between groups in favor of the intervention group; mean systolic blood pressure of -65 mmHg (t = 5.344; p = 0.017) and mean weight of -1.78kg (t = 2.452; p = 0.015). Structured lifestyle modification caused significant improvement on modifiable cardiovascular risk factors in patients with type 2 diabetes mellitus attending the general outpatient clinic of the Jos University Teaching Hospital.

2020 ◽  
Vol 16 ◽  
Author(s):  
Ricardo Cohen ◽  
Noelia S Sforza ◽  
Romina G Clemente

Background: The association between obesity and a reduction in life expectancy is well established, and cardiovascular disease is a leading cause of mortality. Bariatric surgery has long been established as the most effective and durable intervention for obesity, and is the only intervention for obesity that consistently improves multiple comorbidities, reduces cardiovascular disease and long-term mortality. The purpose of this review article is to describe the impact of metabolic/bariatric surgery on type 2 diabetes mellitus and cardiometabolic parameters, including cardiovascular mortality. Methods: A systematic literature search of Pubmed, MEDLINE, and Cochrane Central Register was performed. We included randomized controlled trials, metanalysis, case-control trials, and cohort studies that contain data on reductions in cardiovascular risk factors and cardiovascular mortality in subjects who underwent metabolic/bariatric surgery from January 1, 2005, to June 1, 2020. Conclusion: There is sufficient evidence of randomized controlled trials that metabolic/bariatric surgery is associated with a significant improvement of all cardiovascular risk factors. Although studies are showing a reduction of macrovascular events and cardiovascular mortality, these findings come from observational studies and should be confirmed in randomized clinical trials.


Author(s):  
Milena M. Cojić ◽  
Ljiljana Cvejanov-Kezunović ◽  
Jelena Stanković ◽  
Nebojša Kavarić ◽  
Maja Koraćević ◽  
...  

Some observational studies have shown that only a small number of diabetic patients achieve optimum control of glycaemia and cardiovascular risk factors. The aim of this study was to analyze whether patients with type 2 diabetes mellitus treated in primary care achieve adequate control of glycemic levels and cardiovascular risk factors. This was a retrospective, record-based, cross-sectional study that included eligible patients from 35 to 90 years old with type 2 diabetes mellitus treated in Primary Health Care Center in Podgorica. We investigated electronic records of 531 diabetic patients. The observed prevalence of type 2 diabetes mellitus among individuals between ages 35 and 90 years, was 11,84 %. Half of the patients were female. The mean age was 65,88±9,86 years. The mean value of HbA1c was 7,56±1,71. Fifty-nine percents of patients achieved optimal levels of HbA1c ≤ 7 %. Also, more than half of patients achieved target levels of blood pressure while 27.9% achieved LDL ≤ 2.6 mmol/L. Fifty percent of patients were non-smokers and 45.1 % were obese. Among patients on primary prevention only 5.7 % had met all target levels while on secondary prevention that number was even smaller 3.7 %. Our study showed that control of HbA1c and blood pressure was similar to other studies but reaching target levels of LDL was challenging for our patients. Further analysis are needed in order to discover the reasons for poor control of certain CVRF and to develop strategies for its optimal management.


2020 ◽  
Vol 141 ◽  
pp. 106302
Author(s):  
María Barroso ◽  
M. Dolors Zomeño ◽  
Jorge L. Díaz ◽  
Silvia Pérez-Fernández ◽  
Ruth Martí-Lluch ◽  
...  

2008 ◽  
Vol 25 (3) ◽  
pp. 333-340 ◽  
Author(s):  
N. P. E. Kadoglou ◽  
F. Iliadis ◽  
N. Angelopoulou ◽  
D. Perrea ◽  
C. D. Liapis ◽  
...  

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