scholarly journals AYURVEDIC CONCEPT OF LEUCORRHOEA: SWETA PRADARA

2021 ◽  
Vol 9 (9) ◽  
pp. 2196-2200
Author(s):  
Krishnapriya N ◽  
Kavitha B K

Leucorrhoea is one of the most common and burning problems faced by women all around the globe. It may be physiological but when turning into a pathological condition, produce associated symptoms like itching vulva, backache, and anxiety to female suffering from the entity. Various factors like fungal, parasite, bacterial, and sex- ually transmitted diseases are responsible for the causation of this disease. In Ayurveda, it is termed as Sweta pra- dara. It can be a symptom of many diseases as well as an independent entity. No description of Sweta Pradara has been described by scholars of Brihatrayee. For abnormal white vaginal discharges, the word Sweta Pradara has been described in texts during and after the medieval period. The present study has been designed to substantiate the aetiology, pathogenesis, clinical features and treatment of sweta pradara so that alternative better forms of therapy can be made available in those suffering from Sweta pradara. Keywords: Sweta Pradara, Leucorrhoea, Yonivyapad.

2012 ◽  
Vol 39 (4) ◽  
pp. 849-855 ◽  
Author(s):  
ANTONIO MARCHESONI ◽  
FABIOLA ATZENI ◽  
ANTONIO SPADARO ◽  
ENNIO LUBRANO ◽  
GIUSEPPE PROVENZANO ◽  
...  

Objective.To identify the clinical features that can help to distinguish between psoriatic arthritis (PsA) and fibromyalgia (FM).Methods.Our cross-sectional study was carried out in 10 Italian rheumatology centers between January and September 2009, and enrolled all consecutive patients with PsA and FM who agreed to participate. Standard clinical and laboratory data for PsA and FM were collected from all patients. Records were made of somatic symptoms, response to nonsteroidal antiinflammatory drugs (NSAID), self-evaluated pain, general health, disability, and responses to the Fibromyalgia Impact Questionnaire. Data were statistically analyzed by univariate and multivariate analyses, and receiver-operating characteristic curves. The analysis concentrated on the clinical features shared by the 2 conditions.Results.Two hundred sixty-six patients with PsA (mean age 51.7 yrs; disease duration 10.2 yrs) and 120 patients with FM (mean age 50.2 yrs; disease duration 5.6 yrs) were evaluated. Univariate analysis showed that patients with FM had higher mean tender point and enthesitis scores, more somatic symptoms, and responded less to NSAID. Multivariate analysis showed that the presence of ≥ 6 FM-associated symptoms and ≥ 8 tender points was the best predictor of FM.Conclusion.The shared clinical features of PsA and FM that had the greatest discriminating power for FM were the number of FM-associated symptoms and tender point count.


2020 ◽  
Vol 77 (1) ◽  
pp. 173-188
Author(s):  
Jedidiah Siev ◽  
Jessica Rasmussen ◽  
Alexandra D. W. Sullivan ◽  
Sabine Wilhelm

Cephalalgia ◽  
2015 ◽  
Vol 36 (6) ◽  
pp. 510-517 ◽  
Author(s):  
V Tarasco ◽  
G Grasso ◽  
A Versace ◽  
E Castagno ◽  
F Ricceri ◽  
...  

Aim The aim of this article is to analyze the epidemiological and clinical features of migraine in a pediatric headache center. Methods A retrospective study was performed over six years. Hospital record databases were screened for the diagnosis of migraine with aura (MA) or without aura (MO), based on the ICHD-II criteria. Statistical analysis: Fisher’s test or Mann-Whitney U test, significance at p < 0.05. Results Migraine was diagnosed in 495 children (29.7% MA, 70.3% MO). The majority of diagnoses were made between ages 9 and 14 years. After stratification for age into five groups, we observed an increase of diagnoses in females, with a peak after the age of 15 years, and an increase of MA. In both groups, the attacks were usually severe, infrequent (<1–3/month) lasting <2 hours, and associated with nausea/vomiting, photophobia, phonophobia (more frequent in MO). Osmophobia was reported in 24.7% of the patients with MO. Dizziness was more frequent in patients with MA. Visual auras were the most common occurrence (87.1%). Confusional state was observed in 10.88% of the patients. A positive family history of headache was observed in >88% of the patients. Conclusion We describe the characteristics of pediatric migraine based on the ICHD-II criteria, showing a likely significant loss of diagnoses using the ICHD-III beta. The incidence of migraine increases with age. MO occurs more commonly and shows more frequent attacks and a higher prevalence of associated symptoms, in particular osmophobia. Although males are prevalent in the entire sample, the proportion of females is higher among patients with MA in all of the age groups. Phenotype and sexual prevalence of migraine acquire adult characteristics and become more frequent in females from the onset of puberty.


The aim of the study was to establish the clinical features of the Socially-Disadaptative Post-Combat syndrome as one of the psychopathological states associated with participation in hostilities. To achieve this aim, 482 Ukrainian military personnel who took part in the anti-terrorist operation / Joint Force Operation and requested psychiatric assistance had examined. As part of the study, clinical, anamnestic, psychopathological, psychodiagnostic, follow-up, statistical research methods had used. In the course of the study, it was found that 15% of servicemen combined the presence of a certain group of symptoms, which, due to their clinical-psychopathological continuum, etiology and dynamics features, became possible to combine into a single syndrome, called the “Socially-Disadaptative Post-Combat syndrome”. With this syndrome, the explosiveness, the lability of emotions and moods, dysphorism, emotional stress, conflict, non-conformal, egocentrism, an increased sense of justice, which arose some time after the return of the combatant from the combat zone, prevail. The study found that the debut of this syndrome could be attributed to the group of delayed stress response disorders, but this does not allow the following fact: the main etiological factor of the pathological condition is maladjustment in the social environment, which is caused by alienation and disharmonious perception of civilian life and its associated information space of a person who is faced with the realities of the combat situation and has developed adaptation mechanisms to it. Another etiological component of this syndrome is the emotional stress that has remained after being in a combat zone, which affects the perception of the environment. Not the last etiological component of the Socially-Disadaptative Post-Combat syndrome is the informational component of the “hybrid war” and its consequences, reflected in the verbal and behavioral practices of the civilian population. The elimination of the Socially-Disadaptative Post-Combat syndrome took place on its own immediately upon the return of servicemen to the combat zone or, in the case of a long period of stay of servicemen in a civilian environment, extremely slowly and in the conditions of treatment. The identification and establishment of the clinical features of the Socially-Disadaptative Post-Combat syndrome has expanded the understanding of the psychopathological states from the Combat stress reaction group; however, this psychopathological condition requires further analysis and research.


Blood ◽  
2016 ◽  
Vol 128 (22) ◽  
pp. 3042-3042 ◽  
Author(s):  
Yoshiaki Abe ◽  
Yoshiaki Usui ◽  
Kentaro Narita ◽  
Masami Takeuchi ◽  
Kosei Matsue

Abstract Background: Neurolymphomatosis (NL) is a rare pathological condition of non-Hodgkin lymphoma characterized by infiltration of malignant lymphoma cells into the peripheral nervous system. Patients may develop NL at initial presentation, during disease progression, or as relapse. Diagnosis is often difficult as clinical symptoms of NL are nonspecific and varied. Although nerve biopsy remains the gold standard for diagnosis, it is often unfeasible due to the possible irreversible neurological deficit and its scattered distribution. Prognosis and optimal therapeutic strategy are poorly understood due to its rarity. To clarify the clinical features of NL, we retrospectively analyzed 14 cases of NL with emphasis on diagnosis and treatment. This is a largest series of NL cases as a single institutional report. Method: We reviewed the clinical records of patients admitted to our hospital from April 1, 2006, to April 30, 2016. Diagnosis of NL required: 1) clinical symptoms and neurological findings related to the peripheral nerves; and 2) histological confirmation of malignant lymphoma cells within these nerves; or 3) CT/MRI demonstration of nerve enhancement and/or enlargement of nerve(s) that were also demonstrated by accumulation of FDG on FDG-PET/CT and/or whole-body diffusion weighted whole-body MRI (DW-WBMRI). We surveyed therapeutic contents and analyzed prognosis. Result: Over the past 10 years, 901 patients with NHL were admitted to our hospital; 14 patients (1.6%) were diagnosed with NL (7 men, 7 women, median age: 73.0 years, range: 60 - 84 years). Twelve patients were histologically diagnosed as DLBCL and 5 of them primarily presented with intravascular lymphoma (IVL). Among the 12 DLBCL patients, 8 were positive for CD5 (75.0%). One patient was originally diagnosed as mantle cell lymphoma (MCL), and another one patient was diagnosed as peripheral T-cell lymphoma not otherwise specified (PTCL-NOS). NL occurred as part of primary disease in 3 patients and as relapse in the remaining 11 patients. All patients were diagnosed with NL by neurological findings and imaging studies (contrast-enhanced MRI, PET/CT, and/or DW-WBMRI). All of the patients with relapsed NL showed neither prominent lymphadenopathy nor abnormal laboratory data except neurological abnormalities. In one patient, NL lesions were evaluated by both PET/CT and DW-WBMRI simultaneously. DW-WBMRI had greater sensitivity for detecting NL lesions than PET/CT. Autopsy also confirmed lymphoma infiltration in one patient. Cerebrospinal fluid cytology was positive in 10 cases (71.4%). Twelve patients received high-dose methotrexate (HD-MTX) in addition to systemic chemotherapy. Despite initial responses, rapid disease recurrence occurred in all patients. Neurological symptoms responded promptly in 7 of 8 patients receiving involved nerve irradiation (87.5%). Eleven patients (78.6%) died due to progressive NL. Three patients are still alive 109.0, 39.0 and 3.4 months, respectively, from the diagnosis of NL. The median survival after development of NL was 9.4 months (range: 1.0 - 109.0 months). Three patients received autologous stem cell transplantation (auto-SCT), 2 patients survived for more than 7 years free of disease and the other for 1 month just received transplantation, but the remaining one patient relapsed and died 4 months after auto-SCT. Conclusion: NL is an extremely rare pathological condition (1.6%) and can present in diverse ways, both at initial diagnosis of lymphoma and after treatment. Twelve patients (85.7%) were DLBCL, and 75% of them were CD5-positive. IVL was the most common subtype. Cerebrospinal fluid was positive in 71.4% cases at the time of NL development. Imaging techniques, including contrast-enhanced MRI and PET/CT, are useful and DW-WBMRI may be more sensitive for detecting the relevant neural involvement. Prognosis remains poor once NL has developed despite the use of HD-MTX and rituximab-containing aggressive chemotherapy with or without auto-SCT. Only involved nerve irradiation was effective for temporary relief of neurological symptoms. Disclosures No relevant conflicts of interest to declare.


Author(s):  
Dhakchinamoorthi Krishna Kumar ◽  
Leena Pavitha P. ◽  
Ramachandran Prukruthi ◽  
Fathima Tabassum ◽  
J. B. Shalam Bellja ◽  
...  

<p class="abstract">The term postcholecystectomy syndrome (PCS) refers to varied signs and symptoms attributed to patients on cholecystectomy for the surgical management of symptomatic gallstone disease. This complication occurs as a result of a pathological condition of the gallbladder or attribution of several symptoms. PCS affects about 10-15% of the patients. The management and treatment of PCS associated symptoms are depending on the specific diagnosis and may include pharmacological or surgical management. In the present case, a 74-year-old man undergone for laparoscopic cholecystectomy admitted with complaints of loose stools for several times with other complications (anaemia, leucocytosis, neutrophilia, and also reported known case of trigeminal neuralgia). The present case report added insight information on PCS and its therapeutic management.</p><p class="abstract"> </p>


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