scholarly journals A CONCEPTUAL STUDY ON ETIOLOGY AND AYURVEDIC MANAGEMENT OF MUKHADUSHIKA W.S. R TO ACNE VULGARIS: A REVIEW

2021 ◽  
Vol 9 (7) ◽  
pp. 1538-1543
Author(s):  
Gupta Deepak ◽  
Asthana Alok
Keyword(s):  
Acne Vulgaris ◽  
Treatment Modalities ◽  
Clinical Approach ◽  
Healthy Life ◽  
Inflammatory Lesions ◽  
Causative Factors ◽  
The Face ◽  
Sebum Production ◽  
Conceptual Study ◽  
Major Factors

Ayurveda is considered an ancient healthcare system of India which is based on the eternal principle of healthy life. The whole clinical approach of Ayurveda is based on the preventive, promotive & curative aspects that aim of Ayurveda. Now a days, the whole world is gradually turning towards Ayurveda for a safe and complete cure of diseases, especially in the field of skin problems, Ayurveda can contribute remarkably. Skin is known as the larg- est organ of the human body, which performs many functions like thermoregulation, vitamin D synthesis, sensory perception, immunological function etc. But besides this, it also seems an important symbol of beauty. Acne vul- garis is the most common problem affecting the normal texture of skin bothering teenagers today. This skin con- dition lights the mankind and caricature of youth. Acne vulgaris is known as a disease of the pilosebaceous folli- cle characterized by non-inflammatory (open and closed comedones) and inflammatory lesions (papules, pustules, and nodules). Four major factors involved in the disease production are inflammation, rise in sebum production, cornification of pilosebaceous ducts and microbial involvement. In Ayurveda, Shalmali thorn-like eruptions on the face of a youth caused by Kapha, Vata and Rakta are known as Yuvanpidika. They are also known as Mukha- dushika.1The painful eruptions packed with Meda, similar to the thorns of Shalmali having their site on the face of adults are known as Yuvanpidika2. This article describes the Ayurvedic review of Mukhadushika with Nidan, Pur-varoop, Roop, Samprapti and Chikitsa along with its modern counterpart of Acne with its definition, causative factors, and types of acne, complications and treatment modalities. Keywords: Mukhadushika, Ksudrarogas, Yuvanpidika, Acne vulgaris, Shalmali

scholarly journals ROLE OF JALUKAVACHARAN AND MAHAMANJISHTADI KWATH IN THE MANAGEMENT OF MUKHADUSHIKA W.S.R TO ACNE VULGARIS- A CASE STUDY

2018 ◽  
Vol 6 (8) ◽  
pp. 25-32
Author(s):  
Dhalpe Suchita Jayant ◽  
Vivek S. Chandurkar
Keyword(s):  
Acne Vulgaris ◽  
Burning Sensation ◽  
Inflammatory Lesions ◽  
The Face ◽  
Sebum Production ◽  
Major Factors

Acne vulgaris is a disease of the pilosebaceous follicle characterized by noninflammatory (open and closed comedowns) and inflammatory lesions (papules, pustules, and nodules). There are four major factors involved in the disease production viz. increased sebum production, cornification of pilosebaceous ducts, microbial involvement and inflammation. This condition is found commonly in puberty. In Ayurveda, it is termed as Mukhadushika In Ayurveda Mukhadushika is described under the heading of Kshudrarogas. The Shalmali thorn like eruption on the face due to vitiation of Kapha, Vata and Rakta which are found on the face of adolescent are called as Mukhadushika or YuvanPidika. Although vata, kapha and rakta are mentioned as dosha-duṣya involved in the pathogenesis of the disease, pittaja symptoms are also found in the disease like daha and paka.  Patient was suffering from Acne over face (Pidika), Burning sensation over face (Daha), Itching over face (Kandu), and Discolouration of skin (Vaivarnya) since 6 months. Patient was treated with jalukavacharan and mahamanjishtadi kwath.

scholarly journals Case Report. A Case Report of Adult Acne

2016 ◽  
Vol 9 (2) ◽  
pp. 154-158
Author(s):  
Ivelina A. Yordanova ◽  
Desislava D. Tsvetanova ◽  
Diana D. Strateva ◽  
Pavlina D. Yordanova-Laleva ◽  
Dimitar K. Gospodinov
Keyword(s):  
Case Report ◽  
Sex Hormones ◽  
Skin Diseases ◽  
Acne Vulgaris ◽  
Epidemiologic Studies ◽  
Hair Follicles ◽  
Adult Onset ◽  
Inflammatory Skin Diseases ◽  
The Face ◽  
Sebum Production

Summary Acne vulgaris is among the commonest inflammatory skin diseases affecting pilosebaceous units. It occurs mainly in puberty and affects adolescents at the age of 14-19 years both females and males, in relation to sebum production of hair follicles under the action of sex hormones. Clinically the disease is presented with comedones, papules, pustules, nodules and scars in some cases. Seborrheic areas face, chest and back are affected. Recent epidemiologic studies have shown significant number of female patients aged over 25 years with acne and the term Adult onset acne (AOA)was established.The latter is manifested clinically in the lower third of the face. Primary etiological cause of AOAisahormonal imbalance, mainly hyperandrogenemia. Acase ofa25-year-old woman with adult acne and elevated levels of testosterone and prolactine is presented in this paper.

scholarly journals A Prospective, Randomised, Controlled, Split-Face Clinical Trial to Assess the Safety and the Efficacy of Cold Atmospheric Plasma in the Treatment of Acne Vulgaris

2021 ◽  
Vol 11 (23) ◽  
pp. 11181
Author(s):  
Sigrid Karrer ◽  
Mark Berneburg ◽  
Florian Zeman ◽  
Michael Koller ◽  
Karolina Müller
Keyword(s):  
Acne Vulgaris ◽  
Atmospheric Plasma ◽  
Serious Adverse Events ◽  
Inflammatory Lesions ◽  
Cold Atmospheric Plasma ◽  
Moderate Reduction ◽  
The Face ◽  
Randomised Controlled ◽  
Split Face

The increase in antibiotic resistance requires effective non-antibiotic therapies for acne. Cold atmospheric plasma (CAP) inactivates bacteria and improves wound healing, but its effect on acne has not been investigated. The objective of this controlled split-face study was to assess safety and efficacy of CAP in moderate acne. One side of the face received 8–10 treatments with cold helium plasma within 4–6 weeks; follow-up was two and four weeks thereafter. Acne lesions were counted, followed by global acne severity ratings. Of the 34 patients included, 29 completed the study. No serious adverse events occurred. The two facial sides did not significantly differ in the number of inflammatory and non-inflammatory lesions. An interaction effect of number and type of treatment was found for inflammatory lesions. Lesion reduction after 10 treatments was significantly higher on the treated than on the untreated side. Percentage of patients reporting improved aesthetics was higher for the treated than for the untreated side after treatment completion (79% vs. 45%) and at the two- (72% vs. 45%) and four-week follow-up (79% vs. 52%). In conclusion, CAP was safe with excellent tolerability, showed moderate reduction in acne lesions and led to higher patient-based ratings of aesthetics than non-treatment.

“Yuvanpidika : A modern and Ayurvedic perspective.”

2020 ◽  
Vol 8 (04) ◽  
Author(s):  
Tanvi Sanjay Pawar ◽  
Archana Gharge
Keyword(s):  
Acne Vulgaris ◽  
Self Esteem ◽  
Hair Follicles ◽  
Oil Glands ◽  
Cutibacterium Acnes ◽  
The Face ◽  
Sebum Production ◽  
Chronic Skin ◽  
Local Release ◽  
Chronic Skin Disease

Acne vulgaris is a chronic skin disease of the pilo-sebaceous unit and develops due to blockages in the skin's hair follicles. It is characterized by blackheads or whiteheads, pimples, oily skin, and possible scarring It primarily affects areas of the skin with a relatively high number of oil glands, including the face, upper part of the chest, and back. These blockages are thought to occur as a result of the following four abnormal processes: a higher than normal amount of oily sebum production (influenced by androgens), excessive deposition of keratin protein leading to comedo formation, colonization of the follicle by Cutibacterium acnes (C. acnes) bacteria, and the local release of pro-inflammatory chemicals in the skin. The resulting appearance can lead to anxiety, reduced self-esteem and, in extreme cases, depression or suicidal thoughts. In  Ayurveda, it is termed as Mukhadushika. In Ayurveda, Mukhadushika is described under the heading of Kshudra rogas. These diseases are called as Kshudra because of their lesser severity. According to Sushruta Samhita Nidan Sthana, these are Shalmali thorn like eruption found on the face of adolescents are called as Mukhadushika or Yuvan Pidika. These are impregnated with Meda. Vitiated Vata Dosha, Kapha Dosha and Rakta Dosha are considered to be the main Samprapti Ghatak of Mukhadushika. In Ayurveda treatment of diseases is mainly of two types of Chikitsa are described i.e. Shodhana Chikitsa and Shamana Chikitsa. Similarly in Mukhadushika also Shodhana and Shamana Chikitsa is done.

Sidharthakadi Lepa in Mukhadushika - A Clinical Study

2018 ◽  
Vol 3 (01) ◽  
Author(s):  
Ravindra Angadi ◽  
Rekha J.
Keyword(s):  
Skin Disorder ◽  
Acne Vulgaris ◽  
Response To Therapy ◽  
Inclusion Criteria ◽  
Pilosebaceous Unit ◽  
External Application ◽  
Acne Lesion ◽  
Common Skin ◽  
The Face ◽  
Inflammatory Component

Background: Acne vulgaris is a very common malady of adolescents. It is common enough to be called as a physiological process but is better regarded as a disease due to its inflammatory component and the disfigurement. Acne vulgaris is a common skin disorder of pilosebaceous unit that primarily affects the face which if not treated leads to pigmentation. Mukhadushika is a Kshudra Roga which mainly involves Kapha and Vatadosa with Raktha. This is a common illness affecting 80 % of adolescents. Lepa is one of the external therapies explained in Ayurvedic classics. Objectives: To evaluate the efficacy of Sidharthakadilepa in the management of mukhadushikaw.s.r. to acne vulgaris. Methods: 30 patients fulfilling the inclusion criteria were selected. They were given Sidharthakadi Lepa for external application over face for one month. Patients were observed for changes on 7th, 14th, 21st and 28th day. The response to therapy was evaluated at the end of 28 days by calculating acne lesion score and the efficacy was determined by the percentage reduction in ALS. Results: The analysis revealed that 40% of patients had complete remission, 30% patients showed marked improvement and 30% showed moderate improvement.

scholarly journals Efficacy and Safety of Azelaic Acid Nanocrystal-Loaded In Situ Hydrogel in the Treatment of Acne Vulgaris

Pharmaceutics ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 567
Author(s):  
Ivona Tomić ◽  
Sandra Miočić ◽  
Ivan Pepić ◽  
Dubravka Šimić ◽  
Jelena Filipović-Grčić
Keyword(s):  
Azelaic Acid ◽  
Controlled Trial ◽  
Acne Vulgaris ◽  
Topical Therapy ◽  
Adverse Event Rate ◽  
Double Blind ◽  
Inflammatory Lesions ◽  
First Choice ◽  
In Situ Hydrogel

Acne vulgaris is a common, multifactorial, inflammatory skin disease affecting the pilosebaceous unit. Topical therapy is the first choice in the treatment of mild to moderate acne, and azelaic acid (AZA) is one of the most commonly used drugs. The aim of this study was to evaluate the safety and efficacy of a low-dose azelaic acid nanocrystal (AZA-NC) hydrogel in the treatment of mild to moderate facial acne. The study was designed as a double-blind, randomized controlled trial. Patients were randomized to treatment with AZA-NC hydrogel, 10%, or AZA cream, 20%, administered in quantities of approximately 1 g twice daily for 8 weeks. Efficacy of therapy was measured by the number of lesions and safety by the frequency and severity of adverse events. At week 8, the success rate of treatment with AZA-NC hydrogel, 10%, was 36.51% (p < 0.001) versus 30.37% (p < 0.001) with AZA cream. At week 8, treatment with AZA-NC hydrogel, 10%, resulted in a significant reduction in total inflammatory lesions from baseline of 39.15% (p < 0.001) versus 33.76% (p < 0.001) with AZA cream, and a reduction in non-inflammatory lesions from baseline of 34.58% (p < 0.001) versus 27.96% (p < 0.001) with AZA cream, respectively. The adverse event rate was low and mostly mild.

scholarly journals Is it possible to estimate the need for surgical management in patients with a tubo-ovarian abscess at admission? A retrospective long-term analysis

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Murat Gözüküçük ◽  
Esra Gülen Yıldız
Keyword(s):  
Surgical Treatment ◽  
Antibiotic Therapy ◽  
Treatment Failure ◽  
Medical Treatment ◽  
Length Of Hospital Stay ◽  
Treatment Modalities ◽  
Laboratory Findings ◽  
Factors Affecting ◽  
Laboratory Infection ◽  
Major Factors

Abstract Background This study aimed to determine the possible prognostic factors correlated with the treatment modalities of tubo-ovarian abscesses (TOAs) and thus to assess whether the need for surgery was predictable at the time of initial admission. Materials and methods Between January 2012 and December 2019, patients who were hospitalized with a TOA in our clinic were retrospectively recruited. The age of the patients, clinical and sonographic presentation, pelvic inflammatory risk factors, antibiotic therapy, applied surgical treatment, laboratory infection parameters, and length of hospital stay were recorded. Results The records of 115 patients hospitalized with a prediagnosis of TOA were reviewed for the current study. After hospitalization, TOA was ruled out in 19 patients, and data regarding 96 patients was included for analysis. Twenty-eight (29.2%) patients underwent surgical treatment due to failed antibiotic therapy. Sixty-eight (70.8%) were successfully treated with parenteral antibiotics. Medical treatment failure and need for surgery were more common in patients with a large abscess (volume, > 40 cm3, or diameter, > 5 cm). The group treated by surgical intervention was statistically older than the patients receiving medical treatment (p < 0.05). Conclusions Although the treatment in TOA may vary according to clinical, sonographic, and laboratory findings; age of patients, the abscess size, and volume were seen as the major factors affecting medical treatment failure. Moreover, TOA treatment should be planned on a more individual basis.

scholarly journals Hubungan tingkat kepercayaan diri dengan jerawat (acne vulgaris) pada remaja di SMAN 7 Manado

2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Elga Elfina Ompi ◽  
Lydia David ◽  
H. Opod
Keyword(s):  
Acne Vulgaris ◽  
Physical Appearance ◽  
Cross Sectional ◽  
Internal Factors ◽  
Purposive Sampling ◽  
Rank Analysis ◽  
Self Confidence ◽  
The Face ◽  
Experience Education ◽  
The Relationship

Abstrak. Remaja dengan penampilan fisik berjerawat yang tidak sesuai dengan gambaran idealnya, dikatakan memiliki kepercayaan diri tinggi apabila ia mampu menerima dengan realistis dan mensyukuri serta bertindak positif sedangkan kepercayaan diri rendah apabila remaja tersebut merasa tidak puas, malu, kecewa dan menolak keadaan dirinya. Jerawat atau acne vulgaris adalah peradangan folikel sebasea yang ditandai oleh komedo, papula, pustula, kista dan nodulus di wajah, leher, badan atas dan lengan atas. Jerawat cukup merisaukan karena berhubungan dengan menurunnya kepercayaan diri akibat berkurangnya keindahan wajah penderita. Penelitian ini bertujuan untuk menganalisis hubungan tingkat kepercayaan diri dengan jerawat. Jenis penelitian ini adalah korelasional dengan pendekatan waktu cross sectional (potong lintang). Subyek penelitian adalah siswa/i kelas X-XII SMA Negeri 7 Manado yang berjerawat dengan jumlah 90 responden yang dipilih dengan cara purposive sampling. Untuk menganalisis hubungan antara tingkat kepercayaan diri dengan jerawat digunakan teknik analisis Rank Spearman. Hasil penelitian menunjukkan bahwa nilai koefisien korelasi antara jerawat dengan kepercayaan diri sebesar -0,068, artinya jerawat dengan kepercayaan diri memiliki hubungan negatif dimana keeratan korelasinya sangat lemah (<0,20) sehingga dapat dikatakan tidak terdapat hubungan signifikan antara kepercayaan diri dengan jerawat (Sig=0,523). Artinya, kondisi fisik dalam hal ini jerawat bukan satu-satunya faktor yang mempengaruhi kepercayaan diri. Konsep diri, pengalaman, pendidikan merupakan faktor internal dan orang tua, teman sebaya dan masyarakat merupakan faktor eksternal yang bisa mempengaruhi kepercayaan diri. Responden yang memiliki kepercayaan diri tinggi walaupun berjerawat tidak berorientasi pada penampilan fisik semata, karena mereka merasa yakin akan kemampuan dan potensi dirinya pada hal-hal yang lain.Kata kunci: Remaja, Kepercayaan Diri, Jerawat.Abstract. Adolescents with acne in physical appearance that doesn’t like the ideal appearance, is said that have confidence when he can accept realistically, still feel grateful and act positively while low confidence if these adolescents are not satisfied, embarrassed, disappointed, and rejected themselves. Acne vulgaris is the inflammation of the sebaceous follicles characterized by comedones, papules, pustules, cysts and nodules on the face, neck, upper trunk and upper arms. Acne is troubling because it is related to the degradation of self confidence due to the beauty of the face.This study aimed to analyze the relationship between the level of confidence with acne. This type of study is correlational with cross sectional approach. The subjects are SMAN 7 Manado students who have acnes with 90 respondents chosen by purposive sampling. Spearman Rank analysis techniques is used to.The results showed that the correlation coefficient between acne with confidence at -0.068, meaning the relationship between acne and confidence is negative which the closeness of the correlation is very weak (<0.20) so that it canbe said there is no significant relationship between confidence with acne (Sig = 0.523). It means, the physical appearance in this case the acne is not the only factor affecting confidence. Self-concept, experience, education is the internal factors and their parents, peers and the community are the external factors that can affect confidence. Respondents with high self confidence eventhough have acnes are not oriented on their physical appearance alone, , because they feel confident in the ability and potential for him in other things.Keywords: Adolescents, Confidence, Acne.

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