scholarly journals A COMPARATIVE CLINICAL STUDY TO EVALUATE THE EFFICACY OF RAJAPRAVARTAKA CHURNA AND HINGUVACHADI CHURNA IN PCOS

2021 ◽  
Vol 9 (10) ◽  
pp. 2397-2403
Author(s):  
Shabeena. I. Attar ◽  
Shivale. Digamber
Keyword(s):  
Clinical Study ◽  
Polycystic Ovarian Syndrome ◽  
Causative Factors ◽  
Wide Range ◽  
Calorie Diet ◽  
Comparative Clinical Study ◽  
Group A ◽  
Group B ◽  
Disor Ders ◽  
Ovarian Syndrome

Polycystic Ovarian Syndrome (PCOS) is the most common health problem caused by a disproportion of reproduc- tive hormones with the ovarian expression of various metabolic disorders and a wide range of clinical features such as obesity, menstrual abnormalities and hyperandrogenism. In this modern era, the erratic lifestyle, high- calorie diet and deskbound jobs have resultantly expanded the spread of hormonal disparities and menstrual disor- ders have led to an increased prevalence of PCOS up to 20-30 %. There are similar conditions explained in the classics under the context of Pushpaghni jataharini. The treatment should be Kapha-Vata hara, vatanulomana, dipana, pittavardhaka along with avoidance of causative factors. Considering the above facts, Rajapravartaka churna and Hinguvachadi churna were selected for the study. The present study was aimed to bring out the effect of Ayurveda in PCOS, which is safe and non-hormonal. Objectives of the study: 1) A comprehensive study of PCOS and its congruence in Ayurveda. 2) To study the efficacy of Rajapravartaka churna and Hinguvachadi churna in PCOS and to compare its efficacy. Materials and Methods: A randomized comparative clinical study of two groups, consisting of 20 patients in each group. Group A - Rajapravartaka churna orally in the dose of 3gm twice daily along with tila kwata as an anupana 50ml; before food for a period of two consecutive cycles. Group B was given Hinguvachadi churna orally in the dose of 250mg twice daily along with water; before food for a period of two consecutive cycles. Results and Interpretation: The study has shown a statistically signifi- cant difference between each group in its efficacy. Conclusion: Rajapravartaka churna showed better results thanHinguvachadi churna while taking the account of the percentage of each criterion. Keywords: Polycystic ovarian syndrome, Pushpaghni Jataharini, Rajapravartaka Churna, Hinguvachadi Churna.

scholarly journals COMPARISION OF MYO-INOSITOL VERSUS METFORMIN ON ANTHROPOMETRIC PARAMETERS IN POLYCYSTIC OVARIAN SYNDROME IN WOMEN

2017 ◽  
Vol 9 (4) ◽  
pp. 144 ◽  
Author(s):  
Jyoti Nehra ◽  
Jyoti Kaushal ◽  
Savita Rani Singhal ◽  
Veena Singh Ghalaut
Keyword(s):  
Polycystic Ovarian Syndrome ◽  
Hip Circumference ◽  
Anthropometric Parameters ◽  
Insulin Sensitizers ◽  
Significant Difference ◽  
Comparative Clinical Study ◽  
Group A ◽  
Group B ◽  
To Receive ◽  
Ovarian Syndrome

Objective: The objective of the study was to evaluate and compare the effect of insulin sensitizers i.e. metformin and myoinositol on anthropometric parameters in patients of the Polycystic ovarian syndrome (PCOS).Methods: A prospective, open-labeled, randomized, comparative, clinical study was conducted on 60 patients. The patients were randomly divided into two groups of 30 each to receive either of the following two treatments: group A: Tablet myoinositol 1g twice daily. group B: Tablet metformin 500 mg thrice daily for 24 w. Anthropometric parameters were assessed by measuring body weight, Body mass index (BMI), waist circumference, hip circumference, waist-hip ratio (WHR) at baseline and subsequently at the end of 12 w and 24 w.Results: In both the groups, there was a statistically significant improvement in over a period of 24 w. In group A, the values for weight at baseline, 12 w and 24 w expressed in mean±SEM are 63.96±.90, 62.33±.88 and 61.20±.85 while in group B the values were 63.58±1.88, 62.26±1.74 and 60.86±1.65. In group A, the values for BMI at baseline, 12 w and 24 w were 26.45±.41, 25.78±.42 and 25.31±.40 while in group B the values were 26.09±.76, 25.53±.71 and 24.96±.68 respectively. In group A, WHR values were 0.79±.007, 0.78±.007 and 0.78±.007 while in group B 0.79±.010, 0.79±0.108, 0.79±.011 at baseline, 12 w and 24 w respectively. However, on comparing both the groups at 12 and 24 w, no statistically significant difference was observed in all the parameters.Conclusion: There was a definite improvement in anthropometric parameters with both metformin and myoinositol but on comparing these drugs, no significant difference was observed. Thus, myoinositol can also be used as an alternative to metformin for the treatment of PCOS.

scholarly journals A COMPARATIVE CLINICAL STUDY TO EVALUATE THE EFFECT OF VAMA-NAKARMA WITH MADANAPHALA VARTI AND MADANAPHALA AVALEHYA YOGA IN POLYCYSTIC OVARIAN SYNDROME (PCOS)

2021 ◽  
Vol 9 (10) ◽  
pp. 2353-2361
Author(s):  
Shwetambika Shwetambika ◽  
Ananta. S. Desai ◽  
Shaila Borannavar
Keyword(s):  
Polycystic Ovarian Syndrome ◽  
Endocrine Disorders ◽  
Yoga Group ◽  
Mild Improvement ◽  
Comparative Clinical Study ◽  
Pcos Group ◽  
Group A ◽  
Group B ◽  
Ovarian Syndrome

Polycystic ovarian syndrome is one of the most common endocrine disorders affecting women in their reproduc- tive age group and the most common cause of anovulatory infertility. It is characterized by the presence of men- strual irregularities, infertility, hirsutism, acne, hair loss, insulin resistance, hyperandrogenemia, central obesity and dyslipidemia with a higher risk of developing Diabetes mellitus, endometrial hyperplasia and cardiovascular diseases. It is important to treat these patients early to help them, deal with emotional stress caused by hirsutism, infertility, obesity that is often overlooked with PCOS. So early diagnosis and proper management can help socie- ty to control PCOS so that women can live a healthy, active life and avoid long term complications such as meta- bolic syndrome and cardiovascular disease. The present study has been done to evaluate the effect of Vamana karma with Madanapala Varti and Madanaphala Avalehya yoga in PCOS. Methodology: 40 patients suffering from PCOS. Group A-Vamana karma with MadanaphalaVarti Yoga, Group B - Vamana karma with Madan- aphalaAvalehyaYoga. Result And Conclusion. The test shows that the treatment is not significant in Group A when compared to Group B. Group A overall result is 28.87% and Group B overall result is 32.37%. Both groups showed mild improvement in features of PCOS both clinically and statistically. Keywords: PCOS, Artavakshaya, Vamankarma, Madanaphalavarti and MadanaphalaAvalehya yoga.

scholarly journals A COMPARATIVE CLINICAL STUDY OF CHITRAKAGRANTHYADI KASHAYA AND TRAYANTHYADI KASHAYA IN PCOS

2020 ◽  
Vol 8 (8) ◽  
pp. 4084-4089
Author(s):  
Aswathi. R . S ◽  
Kavitha B. K
Keyword(s):  
Clinical Study ◽  
Clinical Features ◽  
Health Problem ◽  
Metabolic Disorders ◽  
Clinical Parameters ◽  
Wide Range ◽  
Comparative Clinical Study ◽  
Group A ◽  
Group B ◽  
Comprehensive Study

PCOS is an endocrinal disorder and it is the most common health problem caused by disproportion of re-productive hormones with various metabolic disorders with its own origin characterized by a wide range of clinical features such as irregular menstruation, obesity and hyperandrogenism. According to Ayurveda, there is no direct correlation to PCOS is available. There are similar conditions according to the symptoms are explained under the concepts of Pushpaghni Jathaharini. The mode of treatment should be Kapha-Vatahara, Vatanulomana, Pittavardhaka, Srotoshodhaka and Deepana. Considering the above facts Chitraka Granthyadi Kashaya and Trayanthyadi Kashaya are selected for this study. This study was aimed to bring the efficacy of these Kashayas in PCOS. Objectives: 1) A Comprehensive study of PCOS and its congruence in Ayurveda. 2) To study the efficacy of Chitraka Granthyadi Kashaya and Trayanthyadi Kashaya in PCOS and to compare its efficacy. Materials and Methods: A randomizes comparative clinical study of two groups, consisting of 20 patients in each group. Group A was given Chitraka Granthyadi Kashaya, orally in the dose of 50ml twice daily before food for three consecutive cycles. Group B was given Trayanthyadi Kashaya, 50 ml twice daily before food for three consecutive cycles. Result: Clinical parameters were assessed statistically, and results were concluded. The study has shown that statistically difference between each group and its efficacy. Conclusion: Based on observation both the groups showed significant results. Trayanthyadi Kashaya showed better results than Chitraka Granthyadi Kashaya in PCOS.

Comparative Clinical study of Jatyadi Taila and Jatyadi Ghrita in the management of Dushta Vrana

2018 ◽  
Vol 3 (3) ◽  
Author(s):  
Rajendra Joshi ◽  
N. B. Mashetti ◽  
Rakesh Kumar Gujar
Keyword(s):  
Clinical Study ◽  
Burning Sensation ◽  
Normal Process ◽  
Surgical Practice ◽  
Local Factors ◽  
Significant Difference ◽  
Comparative Clinical Study ◽  
Group A ◽  
Contaminated Wound ◽  
Group B

Dushta Vrana is a common and frequently encountered problem faced in surgical practice. The presence of Dushta Vrana worsens the condition of the patient with different complications and may become fatal. Local factors on wound like slough, infection and foreign body, affect the normal process of healing. A healthy wound in a normal body heals earlier with a minimum scar as compared to a contaminated wound. Therefore in this study all the efforts are made to make a Dushta Vrana into a Shuddha Vrana. Once the Vrana becomes Shuddha, Ropana of the Vrana will start. The objective of the study was to evaluate the clinical efficacy of Jatyadi Taila and Jatyadi Ghrita in Dushta Vrana. Clinically diagnosed 60 Patients of Dushta Vrana were randomly divided into two groups, each consisting of 30 Patients. Group A were treated with the Jatyadi Taila and Group B was treated by Jatyadi Ghrita. The results observed was based on the relief obtained on the subjective and objective parameters taken for consideration for this study viz, size of ulcer, discharge, smell, pain, burning sensation, itching and granulation were found significant (P Lass Than 0.05). On the basis of assessment criteria and overall result of treatment, the patients of Jatyadi Taila group showed better results when compared to Jatyadi Ghrita group. Even though statistically there is no much significant difference between the two groups, but by seeing the effect on individual parameters (subjective and objective) and over all response, Jatyadi Taila seems to be effective when compared to Jatyadi Ghrita. It is having more Ropana qualities when compared to Shodhana.

scholarly journals A COMPARATIVE CLINICAL STUDY ON THE EFFECT OF ASHTAVARGAM KASHAYA AND GANDHARVAHASTHADI KASHAYA IN THE MANAGEMENT OF KATIGRAHA w.s.r. TO LUMBAR SPONDYLOSIS

2020 ◽  
Vol 8 (8) ◽  
pp. 4036-4042
Author(s):  
Abeena Raj D P ◽  
Shripathi Acharya
Keyword(s):  
Clinical Study ◽  
Food Habits ◽  
Unhealthy Food ◽  
Lumbar Spondylosis ◽  
Moderate Improvement ◽  
Nutritional Deficit ◽  
Mild Improvement ◽  
Comparative Clinical Study ◽  
Group A ◽  
Group B

Katigraha is a condition in which the vitiated Vata is localizing in the Katipradesha and producing stiff-ness and pain. These symptoms are similar to Lumbar Spondylosis. The degenerative changes due to aging or trauma, changing in lifestyle & work pattern, unhealthy food habits causing nutritional deficit etc., are causing Dhatukshaya and Margavarodha. Here Ashtavarga & Gandharvahasthadi Kashayas are taken to evaluate the effect on Katigraha. Totally 40 patients of Katigraha were selected, divided in to two groups equally. Group A treated with Ashtavargamkashaya and Group B treated with Gandharvahasthadi Kashaya for 30 days. In group A, 55% patients got moderate improvement and 40% patients with mild im-provement in group B, 5%got moderate improvement and 60% got mild improvement. It is concluded that in general statistically significant results were seen in both the groups. AshtavargamKashaya showed better efficacy than Gandharvahasthadikashaya.

scholarly journals A comparative clinical study on the effect of Gudashunti Nasya and Kola Kulattadi Ruksha Sweda in Manyasthamba

2020 ◽  
Vol 5 (03) ◽  
pp. 1-6
Author(s):  
Sandeep K ◽  
Guruprasad G ◽  
Veeraj Hegde
Keyword(s):  
Statistical Analysis ◽  
Clinical Study ◽  
Severe Pain ◽  
Computer Usage ◽  
Before And After ◽  
Comparative Clinical Study ◽  
Group A ◽  
Group B ◽  
Classical Symptom

Due to present day lifestyle, a greater number of people are inclined to desk work and computer usage leading to many disorders. Manyasthamba is one among such disorders where the stiffness of neck with severe pain is the classical symptom which hampers our day to day life. While explaining treatment of Manyasthamba our Acharyas explained Rukshasweda and Nasya Karma as main line of treatment. Here a study was done by taking Gudashunti Yoga explained in Sharangadara Samhita indicated for Nasya and Kolakulattadi Churna indicated in Vatavyadhi explained in Ashtanga Sangraha for Ruksha Churna Sweda. A comparative clinical study of 40 patients suffering from Manyastambha were selected after thorough investigation. Patients were subjected to Nasya Karma in Group A and Ruksha Sweda and Nasya Karma in Group B for 7 days. Patients were assessed based on standard parameters before and after treatment and 7 days follow up. The statistical analysis revealed that there was a significant improvement in parameters like pain and stiffness. Hence proving the efficacy in the condition.

scholarly journals A comparative clinical study to access the role of Basti and Virechana Karma followed by Rasayana in post menopausal Asthikshaya (Osteoporosis)

2020 ◽  
Vol 5 (05) ◽  
pp. 96-103
Author(s):  
Deepa S. Patil ◽  
Prashanth A.S
Keyword(s):  
Clinical Study ◽  
Inclusion Criteria ◽  
Comparative Clinical Study ◽  
Group A ◽  
Post Menopausal ◽  
Group B

Rajonivrutti condition manifests in the end phase of Jarawastha; but its Samprapti begins from the Sandhikala of Madhyamawastha and Jarawastha due to Vatavruddi in womens reaching Rajonivrutti. Postmenopausal Asthikshaya is a disabling disease, which renders women a bedridden life. Here 40 subjects diagnosed with postmenopausal Asthikshaya fulfilling the inclusion criteria were selected for the study and randomly categorized intp two groups as group A and group B each consisting of 20 subjects. Group A received Amapachana with Hinguvachadivati, Yastimadhu Siddha Ksheerabasti administered in Yoga Basti schedule followed by Tritiyatriphala Rasayana. Group B received Amapachana with Hinguvachadivati, Sadhyosnehapana with Amrita Ghrita, Sarvanga Abyanga with Murchita Tilataila followed by Sarvanga Swedana and Sneha Virechana was admistered with Eranda Taila followed by Tritiyatriphala Rasayana was given. Tritiya Triphala Rasayana selected for the present study by adapting all the general principles of prevention and management of Asthikshaya and as it is a well known Rasayana.

scholarly journals A Comparative Clinical Study of Trikarshika Kwatha with and without Lifestyle Modification in the Management of Vatarakta with Special Reference to Hyperuricaemia

2021 ◽  
pp. 10-19
Author(s):  
Md Tanzil Ansari ◽  
Sukumar Ghosh ◽  
Shailendra Kumar Singh
Keyword(s):  
Clinical Study ◽  
Lifestyle Modification ◽  
Test Results ◽  
Before And After ◽  
Comparative Clinical Study ◽  
Group A ◽  
Group B ◽  
High Level ◽  
Urate Crystals

Nowadays, people are more vulnerable to metabolic disorders due to their faulty dietary and behavioural habits. One such disorder is Vatarakta which causes functional impairment due to involvement of Sandhi (joints). It is manifested by Ruk, Toda, Sparsha asahatva, Shopha, Raga, Daha and Stabdhata in Sandhi. Vatarakta can be correlated with Hyperuricaemia or Gout due to similarity in their clinical features. Hyperuricaemia is defined as abnormally high level of uric acid in blood (i.e. >6mg/dl in female and >7mg/dl in male). On the other hand, Gout is an inflammatory response to monosodium urate crystals formed secondary to hyperuricaemia. Aims and objectives: 1. To evaluate the effectiveness of Trikarshika kwatha and lifestyle modification in the management of Vatarakta. 2. To compare the effects of Trikarshika kwatha with and without lifestyle modification in the management of Vatarakta. Materials and methods: Raw herbs of the research formulation were collected after proper identification and Kwatha was prepared for oral administration. For the clinical study, total 60 patients were selected on the basis of selection criteria. Selected patients were randomly divided into two groups. (i) Group A: 30 patients were treated with Trikarshika kwatha. (ii) Group B: 30 patients were treated with Trikarshika kwatha along with Lifestyle modification. Individual patient was treated for 45 days along with follow up at the interval of every 15 days. To assess the effectiveness of treatment, scoring pattern was followed for subjective and objective parameters. They were assessed before and after treatment. The collected data were analysed statistically by using Paired t-test. Results: On the basis of all statistical data, it can be said that patients of Group B showed better results in all parameters in comparison to patients of Group A. Conclusion: Both Trikarshika kwatha and Lifestyle modification are affective but Trikarshika kwatha with Lifestyle modification is more effective than Trikarshika kwatha without Lifestyle modification in the management of Vatarakta.

scholarly journals Effect of progressive resisted exercises and aerobic exercises in the management of polycystic ovarian syndrome among young women- A pilot randomized controlled trial

Biomedicine ◽  
2020 ◽  
Vol 39 (4) ◽  
pp. 608-612
Author(s):  
Veena Kirthika S. ◽  
Jibi Paul ◽  
Senthil Selvam P. ◽  
Sathya Priya V.
Keyword(s):  
Polycystic Ovarian Syndrome ◽  
Exercise Intervention ◽  
Controlled Trial ◽  
Free Testosterone ◽  
Reproductive Age ◽  
Group A ◽  
Young Subjects ◽  
Group B ◽  
Ovarian Syndrome ◽  
Hormonal Levels

Introduction and Aim: Polycystic ovarian syndrome (PCOS) is a heterogenous, multisystem endocrinopathy in women of reproductive age also called as Stein Leventhal syndrome. PCOS is a common female endocrine disorder with prevalence ranging from 2.2% to 26%. Prevalence of PCOS in Indian adolescents is 9.13%. This draws attention to the issue of early diagnosis in adolescent girls. The aim of this study was to determine the effect of progressive resisted exercises (PRE) and aerobic exercises in the management of subjects with PCOS. Materials and Methods: This was an experimental comparative pre and post-test type study. The subjects in the age group of 18-25 years with the diagnosis of PCOS were selected based on Rotterdam criteria and with the BMI ranging between 25-29. Twenty four subjects were recruited and were randomly divided into two groups. group A was treated with PRE +aerobic exercises + diet and group B with aerobic exercises + diet. The duration of the study was 24 weeks and the outcome measures used were BMI, PCOSQ and hormonal levels (SHBG, Free testosterone, HOMA IR, Hs CRP) Results: The result of the study showed that group A treated with PRE + aerobic exercises + diet had significant improvement in BMI at P?0.05 and PCOSQ and specific hormonal levels at P?0.001 when compared to group B. Conclusion: A 24 weeks exercise intervention with a combined PRE +aerobic exercises +diet was superior to aerobic exercises +diet among young subjects with PCOS. Keywords: BMI; quality of life; PRE; PCOSQ; Hormones.

scholarly journals A comparative clinical study between intra-caesarean and interval intra uterine copper device insertion in caesarean deliveries

2019 ◽  
Vol 8 (10) ◽  
pp. 3874
Author(s):  
Geetha Lakshmi R. ◽  
Sornam M. S. ◽  
Thenmozhi G.
Keyword(s):  
Clinical Study ◽  
Infection Rate ◽  
Family Welfare ◽  
Uterine Perforation ◽  
Expulsion Rate ◽  
Insertion Method ◽  
Significant Difference ◽  
Comparative Clinical Study ◽  
Group A ◽  
Group B

Background: Health and family welfare of Indian Ministry, emphasis on postpartum IUCD insertion. Here we conducted a clinical study comparing intra-caesarean and interval CuT-380A insertion in caesarean deliveries.Methods: A systematic study with 150 patients in each group, recruited clients alternately. Group A Intra-Caesarean Cu-T insertion and Group B Interval Cu-T insertion in caesarean deliveries. Groups were followed up at 6th week and 6th month post insertion with a set of parameters. Missed strings, expulsion and infection rates were the primary outcome measures.Results: Infection rate is higher in Group A (2.3%) at 6th week, and at 6th month infection rate is higher in Group B (1.8%). Missed strings are higher in intra-caesarean than in interval insertion method both at 6th week and 6th month follow up p=0.000, hence significant. Expulsion rate is higher in Group A (2.5%) at 6th week, and at 6th month expulsion rate is higher in Group B (1.9%). There are no complications such as uterine perforation or contraceptive failures in both the groups during the study period. By analysis, there are no significant differences in infection and expulsion rates between the groups. For missed strings there is significant difference between the groups with more missed strings in intra-caesarean insertion method.Conclusions: To conclude, intra-caesarean method is equally effective as interval IUCD insertion method without added complications in caesarean deliveries, with advantage of high motivation, good compliance, safety and ease for the provider to deliver services. 

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