scholarly journals MEDICAL MANAGEMENT OF TINEA INFECTION THROUGH SHODHANA AND SHAMANA – A CASE SERIES

2021 ◽  
Vol 9 (9) ◽  
pp. 2029-2036
Author(s):  
Asha A Bhat ◽  
Prashanth A S
Keyword(s):  
Case Series ◽  
Skin Condition ◽  
Wilcoxon Rank Sum Test ◽  
Common Skin ◽  
Skin Conditions ◽  
Almost All ◽  
Continuous Use ◽  
Present Case Study

Skin is one of the most beautiful organs God has ever blessed to anyone. Everyone craves for beautiful skin and makes all possible efforts to make it glow. To achieve this, they are engaged in continuous use of creams, moist- urizers and other cosmetic articles which lead to immediate or long-term skin issues. Itching being the predomi- nant symptom of these cosmetic issues make people highly embarrassed in society. In Ayurveda, almost all skin conditions are explained under one umbrella called Kushta. It is broadly classified into Mahakushta and Kshudra- kushta1. Dadru Kushta one among the Kshudra Kushta is the most common skin condition accounts for 20% in all consultation in general practice2. North Karnataka is well known for its hot and humid conditions making its population at risk of many Tinea infections. Kandu, Raga and Atasi Pushpa Sankashavat Mandala are the cardi- nal features of Dadru3. In the present case study, 40 patients of Dadru Kushta were taken according to inclusion criteria. The combined effect of both Shodhana and Shamana was assessed. Keywords: Dadru Kushta, Aupasargika, Anushangi, Wilcoxon Rank Sum Test

scholarly journals Teriparatide Therapy in a 4-Month-Old With Severe Hypoparathyroidism

2021 ◽  
Vol 27 (1) ◽  
pp. 80-84
Author(s):  
Neelam D. Bhatt ◽  
Julie L. Heh ◽  
Michelle P. Hudspeth ◽  
Kelli W. Williams ◽  
Katherine E. Twombley
Keyword(s):  
Vitamin D ◽  
Calcium Carbonate ◽  
Case Reports ◽  
Pediatric Population ◽  
Case Series ◽  
Hormone Analog ◽  
Serum Ionized Calcium ◽  
Present Case Study

Teriparatide is a human parathyroid hormone analog approved for the treatment of osteoporosis in adult patients. Its use for hypocalcemia and hypoparathyroidism in the pediatric population is described through case reports and small case series; however, larger studies that demonstrate long-term efficacy and safety are limited. At our institution, a 4-month-old premature (gestational age: 32 weeks) infant with multiple congenital anomalies, functional athymia, and severe hypoparathyroidism and receiving calcitriol, vitamin D, and calcium carbonate supplementation was initiated on subcutaneous injection of teriparatide. During the course of treatment, her calcium carbonate, vitamin D, and calcitriol supplementation requirements substantially decreased. Teriparatide effectively increased serum ionized calcium concentrations and decreased serum phosphorus concentrations in the present case-study over a 6-month period. Teriparatide was well tolerated, and no evidence of hypercalcemia was observed throughout treatment.

scholarly journals An Elderly Long-Term Care Resident with Crusted Scabies

2015 ◽  
Vol 26 (1) ◽  
pp. 39-40 ◽  
Author(s):  
Matthew Sandre ◽  
Filip Ralevski ◽  
Neil Rau
Keyword(s):  
Host Response ◽  
Nutritional Deficiencies ◽  
Rapid Reduction ◽  
Term Care ◽  
Delay In Diagnosis ◽  
Common Skin ◽  
Altered Immune Response ◽  
Skin Conditions ◽  
Crusted Scabies

Crusted scabies is a highly contagious form of scabies. Altered immune response, nutritional deficiencies and modified host response are all risk factors for crusted scabies. The authors report a case involving a patient found to have a chronic maculopapular, erythematous rash with large hyperkeratotic, white and grey plaques on the soles of both feet. An ultimate diagnosis of crusted scabies was reached after a delay in diagnosis suspected to be caused by the similarity in appearance to more common skin conditions such as psoriasis. After topical permethrin was unsuccessful, intermittent dosing of oral ivermectin resulted in a rapid reduction in cutaneous plaques.

Social and Conversational Skills Training with Long-Term Psychiatric Inpatients

1986 ◽  
Vol 59 (3) ◽  
pp. 1327-1331 ◽  
Author(s):  
Gary W. Fecteau ◽  
Marilyn Duffy
Keyword(s):  
Group Process ◽  
Psychiatric Inpatients ◽  
Skills Training ◽  
Severe Disabilities ◽  
Emotional Impact ◽  
Psychiatric Institutions ◽  
Conversational Skills ◽  
Present Case Study

Social and conversational skills training has proven effective with chronic psychiatric populations. Little attention, however, has been directed towards examining the use of this training with individuals who have severe disabilities and have not been released from psychiatric institutions to the community. The present case study examined the utility of this training and constraints in attempting to conduct treatment with two groups of 4 and 3 female psychiatric inpatients who averaged 20 yr. of institutionalization. Significant improvement in orientation and attention, reduction in psychotic talk, and gains on three of five conversational skills were noted. Generalization gains were evident on two of the five specific skills. Observations of group process, examination of indicators of emotional impact, and suggestions for practice are discussed.

scholarly journals Body-monitoring with photonic textiles: a reflective heartbeat sensor based on polymer optical fibres

2017 ◽  
Vol 14 (128) ◽  
pp. 20170060 ◽  
Author(s):  
Brit M. Quandt ◽  
Fabian Braun ◽  
Damien Ferrario ◽  
René M. Rossi ◽  
Anke Scheel-Sailer ◽  
...  
Keyword(s):  
Pressure Ulcer ◽  
Wearable Sensors ◽  
Skin Condition ◽  
Optical Fibres ◽  
Sensitive Skin ◽  
Additional Risk ◽  
Skin Conditions ◽  
Static Coefficient Of Friction

Knowledge of an individual's skin condition is important for pressure ulcer prevention. Detecting early changes in skin through perfusion, oxygen saturation values, and pressure on tissue and subsequent therapeutic intervention could increase patients' quality of life drastically. However, most existing sensing options create additional risk of ulcer development due to further pressure on and chafing of the skin. Here, as a first component, we present a flexible, photonic textile-based sensor for the continuous monitoring of the heartbeat and blood flow. Polymer optical fibres (POFs) are melt-spun continuously and characterized optically and mechanically before being embroidered. The resulting sensor shows flexibility when embroidered into a moisture-wicking fabric, and withstands disinfection with hospital-type laundry cycles. Additionally, the new sensor textile shows a lower static coefficient of friction (COF) than conventionally used bedsheets in both dry and sweaty conditions versus a skin model. Finally, we demonstrate the functionality of our sensor by measuring the heartbeat at the forehead in reflection mode and comparing it with commercial finger photoplethysmography for several subjects. Our results will allow the development of flexible, individualized, and fully textile-integrated wearable sensors for sensitive skin conditions and general long-term monitoring of patients with risk for pressure ulcer.

scholarly journals EVALUATION OF THE TREATMENT OF SHWITRA WITH AYURVEDA MODALITIES: A CASE STUDY

2021 ◽  
pp. 8-10
Author(s):  
Verma Priyanka ◽  
Lahange M. Sandeep ◽  
Jain Saurabh ◽  
Sharma Dushyant
Keyword(s):  
Skin Diseases ◽  
Skin Pigmentation ◽  
Neck Region ◽  
Iga Deficiency ◽  
The Body ◽  
Selective Iga Deficiency ◽  
Almost All ◽  
Destruction Of Melanocytes ◽  
Present Case Study

In Ayurveda most of the skin diseases are explained under the term Kushtha. Shwitra is considered as one of the varieties of Kushtha in the Ayurvedic Classics, caused vitiation of Tridoshas and Dhatus like Rakta, Mamsa and Meda. The references of Shwitra are found in almost all the Samhitas like Bruhatrayees and Laghutrayees. Partial or complete loss of skin pigmentation giving rise to white patch on any part of the body is called as leucoderma or vitiligo and in Ayurveda it is called as Shwitra. This depigmentation results due to destruction of melanocytes, which may be unknown in origin or due to autoimmune endocrinopathies selective IgA deficiency. A female patient, aged 20 year suffering from white patches in neck region since 4 year was treated with both Shaman Chikitsa and Sodhan Chikitsa for a period to 4 months with follow up at every 30 days in between, Relief from the complaints was assessed by noting the changes in the size of patch. After 4 months of treatment the size of patch was reduced. The present case study revealed the efficacy of Ayurveda therapy both internal and external for duration of 4 months in the management of Shwitra.

scholarly journals Effect of Ayurvedic Formulation Orally and Karanj tail locally in the management of Vicharchika WSR to Eczema –A case study.

2021 ◽  
Vol 5 (02) ◽  
Author(s):  
Dr. Subhash B. Jamdhade ◽  
Dr.Swati. S. Tayade ◽  
Dr. S. K. Jaiswal ◽  
Dr. Pradnya. S. Jamdhade
Keyword(s):  
Skin Disorder ◽  
Skin Diseases ◽  
Modern Medicine ◽  
The Body ◽  
Broad Term ◽  
Long Time ◽  
Chronic Skin ◽  
Skin Conditions ◽  
Almost All

Skin is the largest and important organ of the body .A number of skin conditions last a long time. some may start in childhood and continue into adulthood. In ayurveda the word Kushta is broad term which cover almost all skin disorder. Skin is the Largest Organ of Human Body. all the skin diseases in Ayurveda have been Classified under the broad heading of” Kushta’ which are furthur Classified in to Mahakushta and Kshudra kushta.                   Vicharchika is defined under kshudra kushta. Vicharchika is kaphapradhan vyadhi it can be correlate with eczema in modern medicine. Eczema is a condition where in patches of skin become inflamed,itchy,cracked,and rough.some types can also cause blisters. . In adults, Eczema appear anywhere, mostly Hand and foot . the affected skin may be blakish ,eruptive .In Ayurvedic terminology symptom of विचर्चिका- १)सकण्डु पिडका श्यावा बहुस्त्रावा   विचर्चिका|| “च.चि.७/२६,यो.र/भा.प्र.५४/२७ vicharchika are  1) Kandu(itching), 2) Shyavata (blackish discolouration), 3)Pidaka (erruption),  4)Bahustrava (disharge), 5)Ruja(pain), 6)Rajyo(marked lining due to thickness of lesion), 7) Rukshata (dryness). Chronic skin conditions typically aren’t curable  but  they can managed using drugs. In spite of presence of antibiotic, antihistamines, steroids etc, the skin disorder remains refractory to treatment But Ayurveda is the repository of skin remedies which are therapeutically safe and effectiveness. In ayurveda there are various drugs formulation mentioned in samhita which show significant effect on vicharchika.

scholarly journals Amelogenesis imperfecta: A case series

2021 ◽  
Vol 7 (3) ◽  
pp. 145-148
Author(s):  
Jijin M J ◽  
Thabsheera P P ◽  
Mohamed Labeeb K P ◽  
Anjana R
Keyword(s):  
Dental Treatment ◽  
Tooth Development ◽  
Genetic Disorders ◽  
Case Series ◽  
Gene Mutations ◽  
Amelogenesis Imperfecta ◽  
Clinical Case Study ◽  
Different Types

Amelogenesis imperfecta (AI) refers to a group of rare genetic disorders that involve tooth development and that are passed down through families as a dominant trait. This condition is characterized by abnormal enamel formation caused by gene mutations that alter the quality and/or quantity of enamel. This dental problem can impact both primary and permanent dentition, varies among affected individuals, and results in esthetic and functional problems. The treatment planning for patients with AI is related to many factors, including the age of the patient, the type and severity of the disorder, intraoral conditions, and the socioeconomic status of the patient. It is crucial to plan a proper remedy, which requires collaboration among dental specialties to execute comprehensive dental treatment in order to provide a long-term solution with adequate esthetics. This clinical case study looks at three different types of amelogenesis imperfecta patients.

scholarly journals An Empirical Research on Study Success in Times of COVID-19 Pandemic – a Case Study

2021 ◽  
pp. 17-35
Author(s):  
Christin Voigt ◽  
◽  
Jonas Kötter ◽  
Natallia Kukharenka ◽  
◽  
...  
Keyword(s):  
Online Learning ◽  
Online Survey ◽  
Influencing Factor ◽  
Study Success ◽  
Path Diagram ◽  
Almost All ◽  
The Impact ◽  
Quantitative And Qualitative Methods

The COVID-19 pandemic and measures to contain it pushed many universities to switch to online learning in the spring of 2020. The changes took place very quickly and it became clear that the long-term consequences of such a transformation are uncertain and require more detailed study. This research attempts to analyze the impact of online learning on study success. This research makes use of a triangulation with quantitative and qualitative methods. Quantitatively, it contains path diagram with various factors that have an impact on the study success at a German university, which is based on a quantitative online survey with 1.529 participants. Qualitatively, 49 interviews were analyzed in order to identify reasons for the risk of failing to achieve study success. The relevance of technology becomes evident in the quantitative analysis, as it manifests itself in almost all categories that affect study success. Moreover, a new influencing factor appeared, the “adaption to digital teaching”, which was often considered important qualitatively.

scholarly journals Immunotherapies for the Treatment of Uveal Melanoma—History and Future

Cancers ◽  
2019 ◽  
Vol 11 (8) ◽  
pp. 1048 ◽  
Author(s):  
Schank ◽  
Hassel
Keyword(s):  
Rare Disease ◽  
Uveal Melanoma ◽  
Case Series ◽  
Standard Of Care ◽  
Definitive Treatment ◽  
Tumor Control ◽  
Standard Of Care Treatment ◽  
One Year ◽  
Almost All

: Background: Uveal melanoma is the most common primary intraocular malignancy among adults. It is, nevertheless, a rare disease, with an incidence of approximately one case per 100,000 individuals per year in Europe. Approximately half of tumors will eventually metastasize, and the liver is the organ usually affected. No standard-of-care treatment exists for metastasized uveal melanoma. Chemotherapies or liver-directed treatments do not usually result in long-term tumor control. Immunotherapies are currently the most promising therapy option available. Methods: We reviewed both relevant recent literature on PubMed concerning the treatment of uveal melanoma with immunotherapies, and currently investigated drugs on ClinicalTrials.gov. Our own experiences with immune checkpoint blockers are included in a case series of 20 patients. Results: Because few clinical trials have been conducted for metastasized uveal melanoma, no definitive treatment strategy exists for this rare disease. The outcomes of most immunotherapies are poor, especially compared with cutaneous melanoma. However, encouraging results have been found for some very recently investigated agents such as the bispecific tebentafusp, for which a remarkably increased one-year overall survival rate, and similarly increased disease control rate, were observed in early phase studies. Conclusions: The treatment of metastatic uveal melanoma remains challenging, and almost all patients still die from the disease. Long-term responses might be achievable by means of new immunological strategies. Patients should therefore be referred to large medical centers where they can take part in controlled clinical studies.

scholarly journals Symurban Nanocrystals for Advanced Anti-Pollution Skincare

Cosmetics ◽  
2020 ◽  
Vol 7 (1) ◽  
pp. 17
Author(s):  
Daniel Köpke ◽  
Sung Min Pyo
Keyword(s):  
Active Agent ◽  
Pollution Level ◽  
Production Methods ◽  
Saturation Solubility ◽  
Aryl Hydrocarbon ◽  
Poorly Soluble ◽  
Amphoteric Surfactants ◽  
Skin Conditions

Several of most common dermatoses worldwide, e.g., psoriasis and atopic dermatitis, are worsened in their clinical picture when the skin is regularly exposed to an increased air pollution level, e.g., particulate matter. This is explainable by the activation of the aryl hydrocarbon receptor (AhR) in the skin, which results in an increased release of proinflammatory cytokines and matrix metalloproteinases. Symurban is a competitive AhR antagonist and thus allows the effective protection of skin. In order to improve its dermal bioavailability as a poorly soluble active agent (0.25 µg/mL), nanocrystals were prepared and evaluated. Nanocrystals are pure active crystals reduced in particle size to the submicron range of 100 to 1000 nm. They feature the properties of nanocrystals, such as increased saturation solubility and dissolution velocity, without having to be declared as nanomaterial. Production methods and parameters were systematically investigated. Wet bead milling at 2000 rpm for 30 min yielded the best results. A z-average of 280 nm was achieved for a 10% Symurban suspension with a polydispersity index of 0.20, indicating a narrow size distribution. For the long-term stabilization of the nanocrystal suspension, the performance of 15 surfactants of different categories and HLB values were investigated and evaluated. It was found that non-ionic surfactants in general were better able to stabilize the system than anionic or amphoteric surfactants. Highest stability of over 12 months at 25 °C was achieved with 2% Plantacare 810 UP, an ECOCERT surfactant with high skin tolerance. The suspension was also chemically long-term stable with >97% of remaining Symurban over 12 months. The saturation solubility of Symurban as nanocrystals was significantly increased from 0.25 to 2.9 μg/mL, which corresponds to a factor of >11. In a case study of one male volunteer with healthy skin conditions, penetration profiles of Symurban nanocrystal hydrogel and commercial anti-pollution serum containing an identical amount of Symurban were determined and compared. After 20 min of exposure, the relative Symurban concentration in the deeper skin layers (tape 19-30) was more than two times higher for nanocrystal hydrogel (16%) than the commercial serum (7%). These results suggest that nanocrystals are a promising delivery system for the poorly soluble anti-pollution agent Symurban.

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