scholarly journals ROLE OF TAGARADI CAPSULE IN THE MANAGEMENT OF ANIDRA (INSONIA) – A CLINICAL STUDY

2020 ◽  
Vol 8 (7) ◽  
pp. 3850-3857
Author(s):  
Rajnik Jadav ◽  
Alankruta Dave ◽  
Swati Dabhi
Keyword(s):  
Rating Scale ◽  
Acute Stage ◽  
Rank Test ◽  
The People ◽  
Falling Asleep ◽  
Signed Rank Test ◽  
Hypnotic Drugs ◽  
Trial Drug ◽  
Almost All

Anidra (Insomnia) is a type of sleep disorder in which individual feels difficulty in falling asleep, staying asleep or both. In Ayurveda, Anidra is indicated as VataNanatmajaVikara by Acharya Charaka. Insomnia affects most of the people at any stage of life due to today’s stressful day to day life. Allopathic hypnotic drugs are used to treat insomnia in acute stage, but long-term use can lead to dependency and withdrawal symptoms along with other side effects. In present study a polyherbal compound Tagaradi Capsule consist extracts of Tagara, Jatamansi, ParsikaYavani, Ashwagandha, Brahmi, Shankhapushpi, Pippalimula and Sarpagandha is used to check its efficacy in the management insomnia. Aim: Role of Tagaradi capsule in the management of Anidra (Insomnia). Materials and methods: Total 33 newly diagnosed patients of age group 18 to 70 years of insomnia who were not taking any other hypnotic medicine were selected and administered 2 capsules each of 500 mg of Tagaradi compound extract along with a cup of warm milk at bedtime for 2 months. Assessment was done considering the overall improvement of sleep quality according to Pittsburgh Insomnia Rating Scale, im-provement in associated complains, relieving of anxiety according to Hamilton Anxiety rating Scale and relieving of depression according to Hamilton Depression Rating Scale. Observations: The information gathered on the basis of observations was subjected to statistical analysis. The Paired ‘t’ test was used to check the significance of objective criteria and Wilcoxon Signed Rank Test was used to check the signifi-cance to subjective criteria. Results: The results showed that the trial drug had highly significant effect on almost all the mentioned parameters of Insomnia.

The potential role of an activity-based guitar program on the anxiety and fulfillment levels of younger relatives of cancer patients: A pilot study

2021 ◽  
pp. 025576142110273
Author(s):  
Erkan Sülün ◽  
Hüseyin Olgaçer ◽  
Hakkı Cengiz Eren
Keyword(s):  
Cancer Patients ◽  
Trait Anxiety ◽  
Potential Role ◽  
Rank Test ◽  
Satisfaction Scale ◽  
Before And After ◽  
Signed Rank Test ◽  
Total State ◽  
Rank Differences

In this study, the authors evaluated the potential role of an activity-based guitar training program on reducing anxiety and providing fulfillment for younger relatives of cancer patients. Ten active members of KHYD (The Society for Relatives of Cancer Patients), between ages 11 and 17 participated in an 8-week guitar education program. The participants filled out two questionnaires before and after their engagement in the 8-week program, one to measure changes in their anxiety levels (State-Trait Anxiety Inventory) and the other to measure changes in their general fulfillment levels (Multidimensional Students’ Life Satisfaction Scale). Wilcoxon signed rank test, as well as descriptive statistics were used in the analysis of data. Mean rank differences were observed to be statistically significant with respect to total state and trait anxiety scores; in both cases, the participants’ scores decreased after their engagement in the program. Statistically significant mean rank differences were also observed in the overall MSLSS scores and its “friends” and “environment” sub-dimensions; with respect to these, participants’ scores increased after their engagement in the program. Recommendations for more comprehensive, larger-scale studies are given at the end.

scholarly journals PENGARUH LAMAZE EXERCISE TERHADAP SKALA NYERI MENSTRUASI (DYSMENORRHOEA) PADA REMAJA PUTRI DI SMA BUDI MULIA JAKARTA

2017 ◽  
Vol 5 (1) ◽  
Author(s):  
Veronica Yeni Rahmawati
Keyword(s):  
Rating Scale ◽  
Numeric Rating Scale ◽  
Rank Test ◽  
Menstrual Pain ◽  
Significance Level ◽  
Signed Rank ◽  
Wide Range ◽  
Post Test ◽  
Signed Rank Test ◽  
Pharmacological Method

Menstrual pain present as cramps (ranging from mild to severe), which may disturb dailyactivities. Lamaze exercise is non pharmacological method which use breathingrelaxation. This research was to analyze Lamaze exercise to reduction of menstrual pain.This study used pra experimental pre post test design. The population was the studentswith menstrual pain at Budi Mulia Senior High School Jakarta. The sampling techniquewas purposive sampling. Thirty one students participated in this study. The independentvariable was Lamaze exercise and the dependent variable was menstrual pain.Instrument which used to measure pain was Visual Analog Numeric Rating Scale. Datawere analyzed with Wilcoxon Signed Rank Test with significance α ≤ 0.005. The resultshowed that Lamaze exercise decreasd menstrual pain. The result of statistical testshowed significance level p = 0.000 and the deviation between pre and post mean is2.32, which means that there was decreasing menstrual pain in student in pre test andpost test. It can be concluded that Lamaze exercise can influence menstrual pain indecrease respondent of the research. Lamaze exercise can provide a relaxing effect.Further experiment with different respondent characteristic to obtain more wide range ofresult.Keywords: menstrual pain, Lamaze, relaxing effect, non pharmacological method

scholarly journals PENGARUH SENAM TERHADAP PENURUNAN KADAR GULA DARAH PADA PENDERITA DM TIPE 2 DI PUSKESMAS PAKIS SURABAYA

2015 ◽  
Vol 6 (1) ◽  
Author(s):  
Lono Wijayanti ◽  
Ghady Anggun M
Keyword(s):  
Diabetes Mellitus ◽  
Blood Sugar ◽  
Diabetes Mellitus Patient ◽  
Rank Test ◽  
Control Group ◽  
Signed Rank ◽  
Wilcoxon Signed Rank Test ◽  
Signed Rank Test ◽  
Almost All

The type of sport suggested for Diabetes Mellitus patient is Diabetes Gym, but most societies, especially diabetes mellitus patients are lazy to do it. On diabetes mellitus type 2, diabetes gym acts as glycemic control which manages and control blood sugar rate. This research purposes to know diabetes gym influence toward the decrease of blood sugar rate on Diabetes Mellitus patient type 2 in Puskesmas Pakis Surabaya. This research used quasy experiment design. Total of the population of all Diabetes Mellitus patients type 2 is 28 respondents taken by probability sampling - simple random sampling technique; 14 respondents in control group and 14 respondents in treatment group. The independent variable is Diabetes Gym and the dependent variable is the decrease of blood sugar rate. Data are collected by using Glucometer, striptest, needle and observation sheet. Data are analyzed by using Wilcoxon signed rank test with α < 0.05. The result of this research shows that almost all of the respondents in the treatment group have a good category of blood sugar decrease after performing gym, meanwhile almost all of the respondents in control group that do not perform gym have an adequate category of blood sugar decrease. Then, the result is analyzed by Wilcoxon signed rank test and obtained ρ (0,019) < α (0,05) so H0 is refused. It means that there is an influence of diabetes gym to the decrease of blood sugar on the Diabetes Mellitus patients type 2 in Puskesmas Pakis Surabaya. Performing Diabetes Gym influences in decreasing blood sugar rate. Therefore, nurse can take a part in leading diabetes patients to perform diabetes gym so it can be used as the therapy in controlling and decreasing blood sugar rate.

Abstract 14276: A Pediatric Cardiology Handbook for the Digital Age

Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Ellis Rochelson ◽  
Bradley C Clark ◽  
Kara Motonaga
Keyword(s):  
Pediatric Cardiology ◽  
Relevant Information ◽  
High Yield ◽  
Rank Test ◽  
Total N ◽  
Yield Information ◽  
Signed Rank Test ◽  
Evidenced Based ◽  
Types Of Information ◽  
Almost All

Background: Pediatric cardiology (PC) fellows, tasked with studying a large and dynamic field, may benefit from a quick-access digital resource that reflects contemporary practice. Objective: To design a PC Handbook smartphone app and evaluate its effectiveness in enhancing the accessibility of information such as guidelines and treatment recommendations for PC fellows. Methods: The PC handbook app was designed for iPhone using XCode and Swift programming. A pre-app electronic survey and instructions for download were sent to U.S. PC fellows followed by a post-app survey within 3 months of use. Fellows were asked to rate the ease of rapid access to various types of information, such as guidelines and normal values, with responses given on a 4-point scale (1 = very difficult, 4 = very easy). Responses were compared pre- and post-app using the Wilcoxon signed-rank test. Results: Two-hundred and thirty PC fellows were contacted; 23% (total n = 53) completed both the pre-app and post-app surveys and were included for analysis. Over half (57%) of fellows used the PC handbook app 1-3 times per month while 17% used it at least 1-3 times per week. After using the app, fellows found it easier to quickly access information in 8 out of 9 domains evaluated (Fig 1). All fellows found the app easy to use (100%), most felt that the app is well-organized (98%), contains reliable information (92%), and is useful for finding quick answers to clinical questions (87%). Almost all (91%) would recommend the app to a colleague. Conclusions: The Peds Cardiology Handbook iPhone app is a useful, reliable tool that provides quick access to high yield information, including various guidelines and references, in one location. Overall, PC fellows found it easier to rapidly access clinically relevant information after using the app, though future studies may be necessary to evaluate long-term use and impact on evidenced-based practice.

Associations between regorafenib-induced adverse events (AEs) and efficacy in metastatic colorectal cancer (mCRC).

2017 ◽  
Vol 35 (4_suppl) ◽  
pp. 556-556 ◽  
Author(s):  
Takeru Wakatsuki ◽  
Eiji Shinozaki ◽  
Mitsukuni Suenaga ◽  
Izuma Nakayama ◽  
Tomohiro Matsushima ◽  
...  
Keyword(s):  
Multivariate Analysis ◽  
Adverse Events ◽  
Univariate Analysis ◽  
Rank Test ◽  
Multikinase Inhibitor ◽  
Log Rank Test ◽  
Kaplan Meier ◽  
Almost All ◽  
Therapy Target

556 Background: It is occasionally recognized that, in molecular targeted therapy, target-specific AEs can surrogate its efficacy, such as skin toxicities and anti-EGFR antibodies. Because of multikinase inhibitor, regorafenib is involved in various kinds of adverse events; however, the clinical associations between AEs and efficacy remain unclear. The aim of this study is to reveal what AEs could surrogate efficacy of regorafenib. Methods: AEs were graded according to CTCAE ver. 4.0. We defined as “CRP increased”, if CRP increased more than 5 mg/dl during treatment compared with the baseline level. Time to treatment failure (TTF) and overall survival (OS) were estimated using Kaplan-Meier methods and compared by the log-rank test. Covariates which were significant in univariate analysis were included in multivariate analysis. Results: One-hundred and two patients were enrolled in this study. Almost all patients were PS 0-1 and received 160mg of regorafenib as an initial dose. The median TTF and the median OS were 2.0 and 8.0 months, respectively. Major AEs were Hand-foot skin reaction (HFSR) in 82.4% (≥Gr3:38.2%), Hypertension (HT) in 39.2% (16.7%), Rash in 23.5% (8.8%), Blood bilirubin increased (BBI) in 58.8% (2.9%), Thrombocytopenia in 48.0% (3.9%), Neutropenia in 20.5% (0%), and CRP increased in 46.1%. Regarding TTF, in univariate analysis, BBI, AST increased Gr0-1, neutropenia, absence of CRP increased, Diarrhea, HFSR, and Rash Gr0-2 were associated with longer TTF. In multivariate analysis, HFSR (HR 0.34 95%CI 0.19-0.63, p = 0.001) and Rash ≥Gr3 (HR 2.43 95%CI 1.13-5.21, p = 0.023) retained to be significant. With respect to OS, in univariate analysis, AST increased Gr0-1, ALT increased Gr0-1, neutropenia, absence of CRP increased, HFSR, and Rash Gr0-2 were associated with longer OS. In multivariate analysis, HFSR (HR 0.47 95%CI 0.24-0.91, p = 0.026), neutropenia (HR 0.54 95%CI 0.30-0.95, p = 0.032) and AST ≥Gr2 (HR 5.72 95%CI 2.11-15.63, p = 0.023) retained to be significant. Conclusions: HFSR and neutropenia might surrogate regorafenib efficacy in mCRC. Elucidation of the mechanisms of these AEs may help to understand which the pathway is the key role of regorafenib treatment in mCRC.

Using distributional semantics in loanword research: A concept-based approach to quantifying semantic specificity of Anglicisms in Spanish

2016 ◽  
Vol 21 (5) ◽  
pp. 521-540 ◽  
Author(s):  
Jacqueline Serigos
Keyword(s):  
Semantic Space ◽  
Rank Test ◽  
Entropy Measure ◽  
New Concepts ◽  
Signed Rank ◽  
Signed Rank Test ◽  
Lower Entropy ◽  
Three Stages ◽  
High Degree

Aims and objectives: This study aims to redress the paucity of research on the semantics of loanwords, by extending and empirically testing Backus’s ((2001). The role of semantic specificity in insertional codeswitching: Evidence from Dutch-Turkish. Jacobson, Rodolfo (Hg): Codeswitching Worldwide. Bd, 2, 125–154) Specificity Hypothesis – ‘Embedded language elements in code-switching have a high degree of semantic specificity’ (p. 128). Approach: Adopting a concept-based approach to examine loanwords in a large, reliable corpus, the study pursues the following question: Do loanwords have a high degree of semantic specificity relative to their receiving-language equivalents? Specificity is operationalized as an entropy measure of the target word’s environment, the assumption being that more specific words have less variety in their surrounding context. Data and analysis: To test this hypothesis, Anglicisms in a 24-million-word newspaper corpus of Argentine Spanish were processed in three stages: detecting loanwords, selecting semantic equivalents, and measuring specificity. Findings/conclusions: A Wilcoxon Signed-Rank Test revealed that loanwords receive significantly lower entropy scores, that is, they are more specific than their Spanish equivalents. The results suggest a possible motive for adopting loanwords when terms already exist in the source language, namely, to utilize words that provide more nuanced meaning. Originality: Methodologically, this study offers innovative applications of computational methods to loanword research, employing a distributional model to measure entropy. Theoretically, it addresses an underrepresented aspect of loanword adoption, semantics, by extending Backus’s hypothesis to loanwords and increasing its scope to data often viewed as ‘monolingual’. Significance/implications: The conclusions offer novel perspectives on loanwords with existing semantic equivalents, often viewed as ‘unnecessary’ when compared to loanwords that introduce new concepts into the recipient language (e.g. blog). With the notion of specificity, we may understand these loanwords as disruptors to the semantic system of the recipient language, dividing up the semantic space formerly occupied solely by the native equivalent, thus increasing the level of nuance expressed in the original concept.

scholarly journals PENGARUH FOOTBATH TREATMENT TERHADAP NYERI POST SECTIO CAESAREA DI RUANG MELATI RSUD DR SOEKARDJO TASIKMALAYA TAHUN 2019

2020 ◽  
Vol 3 (1) ◽  
pp. 1-5
Author(s):  
Detty Chotimah ◽  
Yulia Herliani ◽  
Endang Astiriyani
Keyword(s):  
Rating Scale ◽  
Numerical Rating Scale ◽  
Sampling Technique ◽  
Sectio Caesarea ◽  
Rank Test ◽  
P Value ◽  
Abdominal Incision ◽  
Signed Rank ◽  
Numerical Rating ◽  
Signed Rank Test

Sectio caesarea is a surgical procedure in giving birth with an abdominal incision and uterus that have higher morbidity than normal childbirth. Foot bath treatment is one part of post natal spa can release endorphins in the brain which is a natural pain reliever. The purpose of this research is to determine the effect of foot bath treatment on post SC pain in Melati room RSUD dr Soekardjo Tasikmalaya. This research was used pre eksperimental with pretest posttest design. The research instrument used Numerical Rating Scale (NRS). Sampling technique was used purposive sampling with 30 respondents. Foot bath treatment is done for 15 minutes. The analyzed was by Wilcoxon Signed Rank Test. The result of this research showed that the scale of pain before getting foot bath treatment is mostly moderate pain as many as 26 peoples (87,7%). The scale of pain after getting foot bath treatment is mostly mild pain as many as 25 peoples (83,3%). The result of the statistical test showed p value 0,000 <0,05 it means there is an effect of foot bath treatment to post SC pain.

scholarly journals PENGARUH YOGA PRENATAL TERHADAP NYERI PUNGGUNG PADA IBU HAMIL TRIMESTER II DAN III DI LIA AZZAHRA MOM & BABY SPA TEGAL

2019 ◽  
Vol 3 (2) ◽  
pp. 92
Author(s):  
Sri Tanjung Rejeki ◽  
Yuni Fitriani
Keyword(s):  
Rating Scale ◽  
Rank Test ◽  
Control Group ◽  
P Value ◽  
Control Group Design ◽  
Group Design ◽  
Signed Rank ◽  
Signed Rank Test ◽  
Numeric Pain Rating Scale ◽  
Pain Rating Scale

 Latar Belakang : Kehamilan melibatkan berbagai perubahan fisiologis antara lain perubahan fisik, perubahan sistem pencernaan, sistem respirasi, sistem traktus urinarius,muskuloskeletal dan sirkulasi. Dalam proses adaptasi tidak jarang ibu akan mengalami ketidaknyamanan salah satunya adalah nyeri punggung, meskipun nyeri punggung adalah hal fisiologis namun tetap perlu diberikan suatu penanganan, seperti yoga prenatal. Tujuan : untuk mengetahui pengaruh yoga prenatal terhadap nyeri punggung pada ibu hamil trimester II dan III. Metode penelitrian dengan quasi experiment Desain penelitian Pretest and Postest Without Control Group Design. Jumlah sampel dalam penelitian ini adalah 30 ibu hamil Trimester II dan III, alat ukur kuesioner Numeric Pain Rating Scale (NPRS). Penelitian dilakukan bulan April tahun 2019. Data dianalisis dengan Wilcoxon (Wilcoxon Signed Rank Test). Hasil penelitian menunjukkan adanya pengaruh yoga prenatal terhadap penurunan intensitas nyeri punggung pada ibu hamil trimenster II dan III karena nilai Asym. Sig sebesar 0,000(p value < 0,05).

scholarly journals The Effect of Turmeric Drink and Lavender Aromatherapy Combination on Neck Pain in Batik Craftsmen in Tuban

2021 ◽  
Vol 4 (2) ◽  
pp. 50
Author(s):  
Indriani Dwi Wulandari ◽  
Harmayetty Harmayetty
Keyword(s):  
Neck Pain ◽  
Rating Scale ◽  
Demographic Data ◽  
Muscle Tension ◽  
Numeric Rating Scale ◽  
Rank Test ◽  
Post Test ◽  
Long Time ◽  
Rest Time ◽  
Signed Rank Test

Neck pain in batik craftsmen causes discomfort to work so the efficiency and productivity decrease. Neck pain in batik craftsmen is caused by a bent position when sitting for a long time and done by sitting in a small chair which is usually called a dingklik. The process of canting takes 6-8 hours per day so that the batik craftsmen have a short rest time which causes fatigue and muscle tension. The research objective was to analyze the effect of the combination of turmeric water and lavender aromatherapy on neck pain in batik craftsmen. The research design used was pre-experimental using one- group pre-post test data collection method with a sample size of 74 respondents. Samples were taken using probability sampling techniques. The independent variable in this study is the combination of turmeric water and lavender aromatherapy. The dependent variable in this study was neck pain in batik craftsmen. The instrument in this study used a demographic data questionnaire, a numeric rating scale pain measurement sheet and standard operating procedures for making turmeric water and lavender aromatherapy. The research data obtained were analyzed by Wilcoxon Signed Rank Test α≤0.05. There is an effect of a combination of turmeric water and lavender aromatherapy on neck pain in batik craftsmen in Tuban with a value of α≤0.05, p = 0.000. The combination of turmeric water and lavender aromatherapy can reduce the level of neck pain in batik craftsmen with neck pain complaints.

3p and 10q deletions detected by fluorescence in situ hybridization (FISH): A potential new tool for early detection of non-small cell lung cancer (NSCLC)

2007 ◽  
Vol 25 (18_suppl) ◽  
pp. 7606-7606
Author(s):  
S. Yendamuri ◽  
A. A. Vaporciyan ◽  
T. Zaidi ◽  
R. Fernandez ◽  
D. C. Rice ◽  
...  
Keyword(s):  
Lung Parenchyma ◽  
Normal Lung ◽  
Rank Test ◽  
Fish Analysis ◽  
Mainstem Bronchus ◽  
Deletion Rate ◽  
Chromosomal Deletions ◽  
Signed Rank ◽  
Signed Rank Test

7606 Objectives: To study the feasibility of detecting chromosomal deletions at the 3p and 10q regions in bronchoscopic brush biopsies and touch preparations by FISH and to study their distribution in different areas of the airway in patients with NSCLC. Methods: Bronchoscopic brush biopsies from the mainstem bronchus on the normal side contralateral to the tumor (NBB) and normal mainstem bronchus on the tumor side (TBB) were obtained from 120 patients who underwent surgical resection. Touch preparations from the tumor (TTP) and normal lung parenchyma from the involved lung (NTP) and from bronchi adjacent to the tumor (TAB) were also obtained. Two FISH assays using probes complementary to 3p22.1 and 10q22.3 were used for evaluation of chromosomal deletions at each site. The ratios of the percentage of deletions detected at different anatomical sites were compared using the Wilcoxon signed rank test. Correlations between deletions at TTP and other sites were estimated with a Spearman coefficient. Results: Contralateral normal bronchial tissue (NBB) showed a relatively low deletion rate of 3p and 10q compared to TTP (p<0.0001). FISH on brush biopsies at TBB showed a significantly higher rate of deletions compared to NBB (p<0.05) for both 3p and 10q. A significantly higher deletion rate was seen at TTP compared to NTP at both the 3p (p<0.0001) and 10 q regions (p<0.0001). Significant correlations were seen between the rate of deletions between TTP and TBB at 3p (ρ=0.61, p<0.0001) and between TTP and TAB at 10q (ρ=0.64, p<0.0001). Conclusions: Chromosomal deletions of the 3p and 10q regions can be reliably detected by FISH in bronchoscopic biopsies and touch preparations. As one progresses from the contralateral normal bronchus to the bronchus on the side of tumor and the tumor itself, the percentage of chromosomal deletions increases in a statistically significant fashion,supporting an etiological role of these changes. Deletions at the bronchoscopically normal main and adjacent bronchus on the side of the tumor correlate with an increased deletion rate in the tumor itself. This suggests that FISH analysis of bronchoscopic brushes may be useful for identifying patients at high risk for developing NSCLC. No significant financial relationships to disclose.

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