scholarly journals AN OBSERVATIONAL CLINICAL STUDY TO EVALUATE SHONITADUSHTI NIDANA IN ASRIGDARA

2021 ◽  
Vol 9 (8) ◽  
pp. 1642-1647
Author(s):  
Silviniya Anitharaj Fernandes ◽  
Prasanna N Mogasale ◽  
Arun Kumar M ◽  
Nagaraj S
Keyword(s):  
Risk Factors ◽  
Abnormal Uterine Bleeding ◽  
Uterine Bleeding ◽  
The Body ◽  
Descriptive Statistics ◽  
Menstrual Blood ◽  
Blood Components ◽  
Disease Manifestation ◽  
Cross Sectional ◽  
Recorded Data

Asrigdara is a disease produced by Dosha Prakopa (vitiation of Dosha) along with Rakta Dushti (vitiation of blood components) primarily in Artavaha Srotas characterised by excessive excretion of menstrual blood where the increased Rakta mix with Raja (menstrual blood) thus, the quantity of Raja increases. It refers to all types of Abnormal Uterine Bleeding (AUB), in which Asrigdara is traditionally expressed as menorrhagia, metrorrhagia, polymenorrhea etc. Up to 1/3rd of women is experiencing abnormal uterine bleeding most commonly in menarche and menopause. Still, the cure of Asrigdara is facing difficulty, which shows that the understanding of Asrigdara is still incomplete, and this motivates to determine further, the other risk factors or other pathology involved in asrigdara. Objective: This calls for an evaluation of the possible Shonitha Dushti Nidana in Asrigdara to identify more risk factors. Methods: In this cross-sectional observational study, 36 subjects diagnosed with Asrigdara were selected. The probable incidence of Nidana (causes), in patients, were assessed through a questionnaire de- veloped for the study. The recorded data were analysed with descriptive statistics. Results: Aharaja Nidanas of Asrigdara acts as Viprakrushta Hetu (remote cause) causes Dhatu Pradooshana (vitiation of tissues) in the body. The Nidana Viruddha Ahara causes Rakta Dushti directly. The Manasika Nidanas such as Krodha (anger) is found to act as Vyanjaka Hetu (weak cause) in the manifestation of Asrigdara. Conclusion: Bahya Hetu (externalfactors) triggers Dosha Kopa or causes Dhatu Pradooshana. In Asrigdara patients, Pitta Pradhana Tridosha and Rakta were vitiated to initiate the disease manifestation. Keywords: Asrigdara, Rakta, Abnormal uterine bleeding, Raja.

scholarly journals AN OBSERVATIONAL CLINICAL STUDY TO EVALUATE SHIROROGA NIDANA IN CEREBROVASCULAR ACCIDENT

2021 ◽  
Vol 9 (7) ◽  
pp. 1366-1371
Author(s):  
Lavanya V K ◽  
Arun Kumar M ◽  
Nagaraj S
Keyword(s):  
Risk Factors ◽  
Cerebrovascular Accident ◽  
Haemorrhagic Stroke ◽  
Brain Dysfunction ◽  
Cerebrovascular Diseases ◽  
The Body ◽  
Vascular Pathology ◽  
Disease Manifestation ◽  
Cross Sectional ◽  
Broad Term

Shiroroga is a broad term encompassing various diseases of the head involving Rakta Dushti due to vitiated Doshas.[1] resulting in different neurovascular presentations, which is comparable with the vascular pathology of stroke. Cerebrovascular diseases include some of the most devastating disorders such as ischemic stroke and haemorrhagic stroke, which result in episodes of brain dysfunction.[2] Currently, the stroke incidents in India is much higher and prevention of stroke is the best option, through control and/or avoiding risk factors such as hypertension. Objectives: This calls for an evaluation of the possible Shiroroga Nidana in the development of Cerebro Vascular Accident (CVA) to identify more risk factors. Methods: In this cross-sectional observational study, 30 subjects diagnosed with the cerebrovascular accident were selected. The probable incidence of Nidana (causes), in patients, were assessed through a questionnaire developed for the study. The recorded data were analysed with descriptive statistics. Results: Nidana, like Vegadharana and Rodana causes Rakta Dushti along with Vata Prakopa. Aharaja Nidanas of Shiroroga are similar to that of Rakta Dushti Nidana and directly causes Dhatu Pradooshana in the body. Manasika Nidana or anxiety and emotional stress acts as Vyanjaka or PrerakaHetu in Samprapti of Shiroroga. Conclusion: Bahya Hetu (external factors) triggers Dosha Kopa or causes Dhatu Pradooshana. In CVA patients, Vata Pradhana Tridosha Kopa and Rakta were vitiated to initiate the disease manifestation. Keywords: Cerebrovascular Accident; Nidana; Shiras; Shiroroga; Stroke.

scholarly journals Prediction of Endometrial Hyperplasia and Cancer among Premenopausal Women with Abnormal Uterine Bleeding

2019 ◽  
Vol 2019 ◽  
pp. 1-6 ◽  
Author(s):  
Luca Giannella ◽  
Lillo Bruno Cerami ◽  
Tiziano Setti ◽  
Ezio Bergamini ◽  
Fausto Boselli
Keyword(s):  
Risk Factors ◽  
Logistic Regression ◽  
Prediction Model ◽  
Endometrial Hyperplasia ◽  
Premenopausal Women ◽  
Abnormal Uterine Bleeding ◽  
Uterine Bleeding ◽  
Stepwise Logistic Regression ◽  
Simultaneous Presence ◽  
Endometrial Pathology

Objective. To create a prediction model including clinical variables for the prediction of premalignant/malignant endometrial pathology in premenopausal women with abnormal uterine bleeding (AUB). Methods. This is an observational retrospective study including 240 premenopausal women with AUB referred to diagnostic hysteroscopy. Based on the presence of endometrial hyperplasia (EH) or cancer (EC), the women were divided into cases (EH/EC) and controls (no EH/EC). Univariate, stepwise logistic regression and ROC curve analysis were performed. Results. 12 women had EH/EC (5%). Stepwise logistic regression analysis showed that EH/EC associated significantly with BMI ≥ 30 (OR=7.70, 95% CI 1.90 to 31.17), diabetes (OR=9.71, 95% CI 1.63 to 57.81), and a thickened endometrium (OR=1.20, 95% CI 1.08 to 1.34, criterion > 11 mm). The AUC was 0.854 (95% confidence intervals 0.803 to 0.896, p<0.0001). Considering the pretest probability for EH/EC of 5%, the prediction model with a positive likelihood ratio of 8.14 showed a posttest probability of 30%. The simultaneous presence of two or three risk factors was significantly more common in women with EH/EC than controls (50% vs. 6.6 and 25% vs. 0%, respectively, p<0.0001). Conclusion. When premenopausal vaginal bleeding occurs in diabetic obese women with ET > 11 mm, the percentage of premalignant/malignant endometrial pathology increases by 25%. It is likely that the simultaneous presence of several risk factors is necessary to significantly increase the probability of endometrial pathology.

scholarly journals Knowledge of Stroke Risk Factors among Stroke Survivors in Nigeria

2016 ◽  
Vol 2016 ◽  
pp. 1-5
Author(s):  
Grace Vincent-Onabajo ◽  
Taritei Moses
Keyword(s):  
Risk Factors ◽  
Stroke Risk ◽  
Tertiary Education ◽  
Effective Means ◽  
Descriptive Statistics ◽  
Stroke Survivors ◽  
Questionnaire Data ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Stroke Risk Factors

Background. Knowledge of stroke risk factors is expected to reduce the incidence of stroke—whether first-ever or recurrent. This study examined knowledge of stroke risk factors and its determinants among stroke survivors.Methods. A cross-sectional survey of consenting stroke survivors at two physiotherapy facilities in Nigeria was carried out. Sociodemographic and clinical data were obtained and knowledge of stroke risk factors (defined as the ability to mention at least one correct risk factor) was assessed using open-ended questionnaire. Data were treated with descriptive statistics and logistic regression analysis.Results. Sixty-nine stroke survivors (male = 72.5%; mean ± SD age =49.7±10.6years) participated in the study. Thirty-four (49.4%) participants had knowledge of stroke risk factors. Only educational level was significantly associated with knowledge and participants with tertiary educational qualification were about 48 times (odds ratio = 48.5; CI = 7.6–309.8;P<0.0001) more likely to be knowledgeable than those with no education.Conclusion. Less than half of the participants had knowledge of stroke risk factors. Participants with tertiary education were significantly more knowledgeable than those with lower educational qualifications. Effective means of educating stroke survivors on stroke risk factors should be identified and adopted.

scholarly journals Schizophrenic patients’ cognitive functions in relation to their metabolic profile: a cross-sectional, comparative study on an Egyptian sample

2020 ◽  
Vol 27 (1) ◽  
Author(s):  
Dalia Hegazy Ali ◽  
Doha Mostafa Elserafi ◽  
Marwa Abdel Rahman Soltan ◽  
Mohamed Fikry Eissa ◽  
Hanan Ahmed Zein ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cognitive Impairment ◽  
Cognitive Abilities ◽  
Metabolic Profile ◽  
Fasting Blood Glucose ◽  
The Body ◽  
Close Monitoring ◽  
Outpatient Services ◽  
Cross Sectional ◽  
Early Management

Abstract Background Patients with schizophrenia suffer from diffuse cognitive impairment and high prevalence of cardiovascular metabolic risks, associated with poor clinical outcomes. We aimed in this study to test the presence of cognitive impairment in a sample of patients with schizophrenia, and evaluate its possible relations to patients’ metabolic profile. We recruited forty patients diagnosed with schizophrenia and their matched controls from the inpatient departments and outpatient services from January to December 2016. Schizophrenia diagnosis was confirmed by the ICD10 criteria checklist. Symptoms profile and severity were assessed by the Positive and Negative Syndrome Scale. Cognitive profile was assessed through (1) Trail Making Test, Parts A and B and (2) Wechsler Memory Scale-Revised Visual Reproduction Test. Metabolic profile was assessed by measuring the body mass index, fasting blood glucose, and lipid profile. SPSS (V. 22.0, IBM Corp., USA, 2013) was used for data analysis. Results The patients group had a significantly higher means in the speed of processing, executive function, attention, and working memory scores on TMT-A (p = 0.0), TMT-B (p = 0.00), and WMS-R (p = 0.029) and significantly higher FBG levels (p = 0.00). Correlation studies showed that the increase in patients’ age, illness duration, treatments, number of hospitalizations, number of episodes and of ECT sessions received, symptoms severity, and deficits in cognitive function scores was associated with higher BMI and FBG. Conclusions Patients with schizophrenia have a higher prevalence of cognitive impairment and vascular risk factors than the general population. Close monitoring and early management of these risk factors can promote better cognitive abilities and overall functions.

scholarly journals Thyroid abnormality in abnormal uterine bleeding: an observational study from Medical College in Eastern UP, India

2017 ◽  
Vol 7 (1) ◽  
pp. 308
Author(s):  
Prachi Singh ◽  
Prashant Dubey ◽  
Shweta Yadav ◽  
Sachin Singh Yadav
Keyword(s):  
Observational Study ◽  
Thyroid Function ◽  
Abnormal Uterine Bleeding ◽  
Uterine Bleeding ◽  
Reproductive Age ◽  
Thyroid Function Tests ◽  
Cross Sectional ◽  
Medical College ◽  
Hormonal Imbalance ◽  
Euthyroid Status

Background: Abnormal Uterine Bleeding (AUB) is one of the commonest gynecological complain in reproductive age group. Menstrual abnormalities are commonly seen when there is any alteration in thyroid function. Objective of present study was to investigate the prevalence of AUB and to determine the menstrual pattern in cases with thyroid dysfunction.Methods: The present cross sectional observational study was conducted Teerthankar Mahaveer Medical College and Research Center Moradabad. Total 400 cases presenting with AUB were included in the study. Routine blood test, ultrasonography and thyroid function tests were done in these cases.Results: Among all the cases presenting with menstrual abnormalities 26% had hypothyroidism and 9% have hyperthyroidism and rest had euthyroid status. Menorrhagia (45.2%) and polymenorrhoea (37.5%) were commonest menstrual abnormality seen in cases with hypothyroidism. Most cases with hyperthyroidism presented with hypomenorrhoea (27.8%).Conclusions: Thyroid function abnormality is common in cases presenting with AUB and it gets relieved in correcting hormonal imbalance.

scholarly journals Evaluation of the diagnostic accuracy of transvaginal sonography versus hysteroscopy in detection of submucous myomas in peri and postmenopausal women with abnormal uterine bleeding

2021 ◽  
Vol 10 (10) ◽  
pp. 3885
Author(s):  
Kushla Pathania ◽  
Surbhi Sharma
Keyword(s):  
Diagnostic Accuracy ◽  
Postmenopausal Women ◽  
Abnormal Uterine Bleeding ◽  
Uterine Bleeding ◽  
Transvaginal Sonography ◽  
Cross Sectional ◽  
Predictive Values ◽  
Menopausal Women ◽  
Submucous Fibroid ◽  
Post Menopausal

Background: Abnormal uterine bleeding is a very common gynaecological condition that affects all age groups. This study was aimed at assessing the usefulness of TVS in comparison with hysteroscopy in AUB evaluation. Aim was to evaluate the diagnostic accuracy of transvaginal sonography versus hysteroscopy in detection of submucous myomas in peri and postmenopausal women with abnormal uterine bleeding.Methods: The present study was prospective cross sectional study conducted in the Department of Obstetrics and Gynaecology, Kamla Nehru State Hospital for Mother and Child Indira Gandhi Medical College Shimla for period of one year w.e.f. 1st May 2018 to 30th April 2019. The study was started after hospital ethical committee approval. 76 patients peri and post-menopausal women were enrolled in the study after taking written consent.Results: On TVS- all the study subjects underwent TVS examination, submucous fibroid was detected in 10 subjects (n= 76) i.e. 13.1% (all perimenopausal). On hysteroscopy submucous fibroid was detected in 11 (14.4%) subjects, on histopathology it was confirmed in 11 subjects (14.4%). Out of 11, 8 patients underwent hysterectomy, 1 myomectomy, 2 patients had hysteroscopic removal of fibroid. 1 subject with AUB-LSM was wrongly diagnosed as AUB-P. Sensitivity, specificity, positive and negative predictive values of transvaginal sonography versus hysteroscopy was 90.09%, 100%, 100%, 98.5% respectively.Conclusions: TVS is an important initial modality for evaluating the patient of AUB. It is quick, simple, painless, least invasive, less expensive and readily available procedure and does not need full bladder like TAS. On the other hand, hysteroscopy has a better diagnostic accuracy as it provides the option of see and treat which is recommended for peri and post-menopausal women with AUB.

Pediatric dog bites: a population-based profile

2018 ◽  
Vol 25 (4) ◽  
pp. 290-294 ◽  
Author(s):  
Jackson Fein ◽  
David Bogumil ◽  
Jeffrey S Upperman ◽  
Rita V Burke
Keyword(s):  
Risk Factors ◽  
Data Bank ◽  
Population Based ◽  
The Body ◽  
Body Region ◽  
Cross Sectional ◽  
Dog Bites ◽  
Severity Of Injury ◽  
The Face ◽  
At Home

BackgroundPrevious studies have identified risk factors for dog bites in children, but use data from individual trauma centers, with limited generalizability. This study identifies a population risk profile for pediatric dog bites using the National Trauma Data Bank. We hypothesized that the population at risk was younger boys, that such bites occur at home, are moderately severe, and are on the face or neck.MethodsFor this retrospective cross-sectional study, a sample of 7912 children 17 years old and younger with International Classification of Diseases (ICD)-9 event code E906.0, for dog bites, were identified. Datasets from 2007 to 2014 were used. Data included patient’s gender, age, ICD-9 primary and location E-codes, AIS body region and AIS severity.ResultsMost children were 6–12 years old and female, but a similar number fell into the narrower range of 0–2 years old. Injuries in the younger group frequently occurred at home, on the face and head, and with minor severity. Age of the child predicts the location of incident (P<0.001), the severity of injury (P<0.001) and the body region of the injury (P<0.001). Body region of the injury predicted its severity (P<0.001).DiscussionYounger children are more likely to receive dog bites, and bites incurred are likely of greater severity. Children this young cannot yet be taught how to properly interact with a dog.ConclusionsDog bites are a significant source of morbidity for children. Based on the population risk factors profile generated, this study recommends targeting live dog education towards the parents of young children.

scholarly journals Lameness in Sheltered Cows and Its Association with Cow and Shelter Attributes

Animals ◽  
2019 ◽  
Vol 9 (6) ◽  
pp. 360 ◽  
Author(s):  
Arvind Sharma ◽  
Clive J. C. Phillips
Keyword(s):  
Risk Factors ◽  
Body Condition ◽  
Body Condition Score ◽  
Cross Sectional Study ◽  
The Body ◽  
Cross Sectional ◽  
Joint Injuries ◽  
Condition Score ◽  
Carpal Joint ◽  
Associated Risk Factors

The sheltering of old, unproductive and abandoned cows in traditional cow shelters, known as gaushalas, has been practiced in India since ancient times. Cows are kept in these shelters until they die of natural causes. The welfare of the cows in these shelters was assessed through a cross-sectional study of 54 cow shelters in six states of India. A total of 1620 cows were examined to assess the prevalence of lameness in these cows, and the associated risk factors for lameness were identified through the measurement of animal-based and resource-based welfare indicators. The overall lameness prevalence was 4.2%. The majority (86%) had mild to moderate hock joint swellings but no or only mild carpal joint injuries. Approximately one-half had mild to moderate hock joint hair loss and most were free of hock joint ulcerations. Claw overgrowth was present in almost one half of the cows. Lameness prevalence was positively correlated with coat dirtiness, hock and carpal joint lesions, diarrhea and claw overgrowth scores. In a multivariate analysis, lameness prevalence increased as the Body Condition Score (BCS) decreased and was associated with increased udder dirtiness, the ulceration of the hock joint, carpal joint injuries and claw overgrowth. Resource-based indicators measured at the shelter level suggested that an absence of bedding in the sheds and an increase in the gradient of the shed flooring increased lameness. Addressing the principle risk factors identified for lameness in the sheltered cows (low body condition, dirty udders, lesions on the hock and carpal joints, overgrown claws, and a steep floor gradient) may help to reduce this serious animal welfare problem.

scholarly journals Thyroid disorders in women with dysfunctional uterine bleeding

2016 ◽  
Vol 6 (12) ◽  
pp. 1018-1020
Author(s):  
S Subedi ◽  
B Banerjee ◽  
C Manisha
Keyword(s):  
Reproductive Function ◽  
Hormonal Treatment ◽  
Abnormal Uterine Bleeding ◽  
Cross Sectional Study ◽  
Uterine Bleeding ◽  
Thyroid Disorders ◽  
Thyroid Disorder ◽  
Dysfunctional Uterine Bleeding ◽  
Cross Sectional ◽  
Menstrual Pattern

Background: Thyroid hormones play a key role in the menstrual and reproductive function of women .It is recognized universally that menstrual disturbances may accompany clinical alteration in thyroid function and every clinician has encountered altered menstrual pattern among women suffering from thyroid disorders. The aim of this study was to find the incidence of thyroid disorders in Dysfunctional uterine bleeding and its correlation with menstrual patterns.Materials and Methods: A hospital based cross-sectional study including 75 cases with dysfunctional uterine bleeding attending the OPD of Nobel Medical College, where incidence of thyroid disorder was evaluated along with its correlation with menstrual patterns and histopathology.Results: The incidence of Gynecological OPD attendance due to abnormal uterine bleeding was 3%.and the incidence of thyroid dysfunction was 10.6% with hypothyroidism being the commonest. (9.3%). The commonest menstrual pattern found was menorrhagia/polymenorrhoea in 8 percent.Conclusion: Prevalence of hypothyroidism was more common in DUB. Thus every woman with menstrual irregularities should undergo thyroid assessment and this will ultimately avoid unnecessary intervention like misuse of hormonal treatment and hysterectomy.

scholarly journals Prevalence of thyroid dysfunction in women with abnormal uterine bleeding in reproductive age

2020 ◽  
Vol 9 (7) ◽  
pp. 2792
Author(s):  
Hema K. R. ◽  
Girish B. L. ◽  
Dhananjaya B. S. ◽  
Riyaj Ahmad Kalaburgi
Keyword(s):  
Thyroid Dysfunction ◽  
Abnormal Uterine Bleeding ◽  
Cross Sectional Study ◽  
Uterine Bleeding ◽  
Reproductive Age ◽  
Inclusion Criteria ◽  
Cross Sectional ◽  
Medical College ◽  
Thyroid Profile ◽  
Definitive Management

Background: Abnormal uterine bleeding (AUB) is one of the commonest presentations encountered in gynecological outpatient department. Menstruation is also regulated by many mechanisms, including thyroid hormone. So, for definitive management of AUB, it becomes imperative to assess thyroid status in those with abnormal uterine bleeding.Methods: Cross sectional study was conducted on all woman attending to OPD at Sri Siddhartha Medical College, Tumukuru, with complaints of abnormal uterine bleeding (AUB). Thyroid test was done for those who were eligible under inclusion criteria. Incidence of thyroid disorders among AUB and type of abnormal menstrual pattern associated with specific type of thyroid dysfunction were noted in this study.Results: Total of 522 presented with AUB. AUB was most common among woman age >40 years at 49.23% (257 of total 522 cases). AUB was more common in Multipara at 61.49% (321 of 522 cases). Menorrhagia was commonest pattern in AUB accounting for 51.34% (268 of 522cases). Thyroid dysfunction was present in 12.27% (64 of 522) of cases with AUB. Among them hypothyroid was most common accounting for 8.81% (46 of 522 cases). Hyperthyroidism was present in 3.44% (18 of 522 cases). Menorrhagia was most common pattern in Hypothyroidism at 65.21% (30 of 46 cases, followed by polymenorrhea at 17.39% (8 of 46 cases). Oligomenorrhea was most common in hyperthyroid group at 55.54% (10 of 18 cases) closely followed by hypomenorrhea at 44.44% (8 of 18 cases).Conclusions: Abnormal uterine bleeding (AUB) is one of the commonest gynecological complaint at gynecological OPD.  Thyroid dysfunction is noted consistently in cases of AUB. So, evaluation of thyroid profile should be part of evaluation of AUB, especially during perimenopause.

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