scholarly journals AYURVEDIC PERSPECTIVE OF PRIMARY DYSMENORRHOEA - REVIEW ARTICLE

2021 ◽  
Vol p5 (03) ◽  
pp. 2780-2786
Author(s):  
Asitha. H ◽  
Vijayakumar N.
Keyword(s):  
Review Article ◽  
Menstrual Blood ◽  
Reverse Direction ◽  
Clear View ◽  
Menstrual Flow ◽  
Primary Dysmenorrhoea ◽  
High Prevalence ◽  
Medical Term

The medical term for painful period is "dysmenorrhoea". Dysmenorrhoea among adolescents is of primary in nature that is without any pelvic pathology. Among Vimshati yonirogas described in Ayurveda classics Udavarta is men- tioned as a condition with painful and difficult menstruation, so it can be correlated to primary dysmenorrhoea. In this condition the Rajas flow in reverse direction hence the term Udavartini. Women feel immediate relief following discharge of menstrual blood. Normal menstrual flow is the function of Apana vata therefore Apana vata dushti can be considered as the responsible factor for Udavarta. Because of the high prevalence of dysmenorrhoea in adoles- cents and extent of its potential daily interference it should be seriously taken into consideration. Ayurvedic classic textbook along with available modern literatures were referred to make a clear view regarding the concept of Uda- varta and its possible correlation with primary dysmenorrhoea. Keywords: Primary dysmenorrhoea, Udavarta, dysmenorrhea

ROLE OF RAJAHPRAVARTINI VATI IN THE MANAGEMENT OF PRIMARY DYSMENORRHOEA (KASHTARTAVA) – A CLINICAL STUDY

2020 ◽  
Vol 8 (10) ◽  
pp. 4633-4642
Author(s):  
Namrata Patel ◽  
Sanjay Srivastava ◽  
Bharti Dadlani ◽  
Basanti Guru
Keyword(s):  
Clinical Intervention ◽  
Menstrual Blood ◽  
Reverse Direction ◽  
Control Group ◽  
Upward Movement ◽  
Trial Group ◽  
Average Percentage ◽  
Primary Dysmenorrhoea ◽  
Group A ◽  
Group B

Dysmenorrhoea is the most common Gynaecological problem with painful menstruation due to increased levels of prostaglandins in the menstrual fluid, this results in uterine pain, nausea, vomiting, backache, diar-rhoea, giddiness, syncope and fainting. In Ayurveda it is explained in terms of "Kashtartava", which is clinical entity characterized by pain and difficult expulsion of Aartva (Menstrual Blood) due to upward movement of Raja (Menstrual Blood), through Pratiloma Gati (Movement in reverse direction) of Apana Vayu and subsides after expulsion of Artava. Formation of Artava (Menstrual Blood) takes place during entire month, due to continuous filling of Garbhashaya through small capillaries, which is brought into Yo-ni and makes it to discharge outside every month by Vayu. The whole mechanism depends upon the proper functioning of Apana and Vyana Vayu where in Apana Vayu is responsible for Raja Pravritii while Vyana Vayu is accountable for blood circulation. In clinical intervention study, purposive randomly selected 40 patients were equally divided into 2 groups i.e. Group A (Trial Group) and Group B (Control Group). In Trial Group Rajahpravartini Vati in dose 250 mg twice a day and in Control Group Placebo (Roasted wheat flour) 2 Capsule twice a day were advised for treatment. drug administration was started from 21st day of LMP to next 3 days of menstrual cycle for duration of consecutively 3 menstrual cycles. It was found that average percentage of relief was higher in group A i.e. 71% while in group B i.e. 43.10%.

Computational Overview of Mycobacterial Thymidine Monophosphate Kinase

2020 ◽  
Vol 26 (15) ◽  
pp. 1676-1681
Author(s):  
Sana Gul ◽  
Ruqaiya Khalil ◽  
Zaheer Ul-Haq ◽  
Mohammad S. Mubarak
Keyword(s):  
Molecular Docking ◽  
Structure Elucidation ◽  
Tuberculosis Patient ◽  
Review Article ◽  
Morbidity Rate ◽  
Drug Resistant ◽  
Tuberculosis Control ◽  
Bacterial Enzyme ◽  
High Prevalence ◽  
Thymidine Monophosphate

: Tuberculosis (TB) ranks among the diseases with the highest morbidity rate with significantly high prevalence in developing countries. Globally, tuberculosis poses the most substantial burden of mortality. Further, a partially treated tuberculosis patient is worse than untreated; they may lead to standing out as a critical obstacle to global tuberculosis control. The emergence of multi-drug resistant (MDR) and extremely drug-resistant (XDR) strains, and co-infection of HIV further worsen the situation. The present review article discusses validated targets of the bacterial enzyme thymidine monophosphate kinase (TMPK). TMPKMTB enzyme belongs to the nucleoside monophosphate kinases (NMPKs) family. It is involved in phosphorylation of TMP to TDP, and TDP is phosphorylated to TTP. This review highlights structure elucidation of TMP enzymes and their inhibitors study on TMP scaffold, and it also discusses different techniques; including molecular docking, virtual screening, 3DPharmacophore, QSAR for finding anti-tubercular agents.

scholarly journals PAIN MANAGEMENT IN PRIMARY DYSMENORRHOEA AND ENDOMETRIOSIS- AYURVEDIC PERSPECTIVE

2021 ◽  
pp. 84-88
Author(s):  
Asitha.H
Keyword(s):  
Pain Management ◽  
Treatment Modalities ◽  
Clear View ◽  
Unpleasant Sensation ◽  
Primary Dysmenorrhoea ◽  
Adolescent Period ◽  
Experience Pain

Pain is generally described as an unpleasant sensation and a universally understood sign of disease. Around 80% of women experience pain during periods from adolescent period right up to menopause. Dysmenorrhoea literally means painful menstruation. Primary dysmenorrhoea is one where there is no identifiable pelvic pathology. The pain begins a few hours before or just with the onset of menstruation and lasts for 24-48 hours. Secondary dysmenorrhoea is normally considered to be menstruation –associated pain occurring in the presence of pelvic pathology. Pain starts 7-8 days before menstruation. Endometriosis is one of the main causes of secondary dysmenorrhoea. Dysmenorrhoea can be correlated to Udavarta and endometriosis to Vatiki. In Udavarta, Sanga and Vimargagamana of Vata and derangement of Kapha pitta is responsible for pain. In Vatiki there is Apana vata vimargagamana, Vyana vata and Pitta vitiation causes Artava dusti and Dusta artava sthana samsraya in Kha vaigunya sites. So administration of drugs and treatment modalities crackling these factors involved in the etiopathogenesis do the work. Ayurvedic classic textbook along with available modern literatures were referred to make a clear view regarding the concept of pain and the main Yonirogas causing pain during menstruation and its management.

scholarly journals Nonalcoholic steatohepatitis in posttransplantation liver: Review article

2018 ◽  
Vol 64 (2) ◽  
pp. 187-194 ◽  
Author(s):  
Antônio Ricardo Cardia Ferraz de Andrade ◽  
Helma P. Cotrim ◽  
Paulo L. Bittencourt ◽  
Carolina G. Almeida ◽  
Ney Christian Amaral Boa Sorte
Keyword(s):  
Nonalcoholic Steatohepatitis ◽  
Clinical Characteristics ◽  
Metabolic Disorders ◽  
Patient Survival ◽  
De Novo ◽  
Review Article ◽  
Liver Transplants ◽  
The Third ◽  
High Prevalence ◽  
The World

Summary Introduction: Nonalcoholic steatohepatitis (NASH) associated or not with cirrhosis is the third leading indication for liver transplantation (LT) around the world. After transplants, NASH has a high prevalence and occurs as both recurrent and de novo manifestations. De novo NASH can also occur in allografts of patients transplanted for non-NASH liver disease. Objective: To evaluate recurrent or de novo NASH in post-LT patients. Method: A literature review was performed using search engines of indexed scientific material, including Medline (by PubMed), Scielo and Lilacs, to identify articles published in Portuguese and English until August 2016. Eligible studies included: place and year of publication, prevalence, clinical characteristics, risk factors and survival. Results: A total of 110 articles were identified and 63 were selected. Most of the studies evaluated recurrence and survival after LT. Survival reached 90-100% in 1 year and 52-100% in 5 years. Recurrence of NAFLD (steatosis) was described in 15-100% and NASH, in 4-71%. NAFLD and de novo NASH were observed in 18-67% and 3-17%, respectively. Metabolic syndrome, diabetes mellitus, dyslipidemia and hypertension were seen in 45-58%, 18-59%, 25-66% and 52-82%, respectively. Conclusion: After liver transplants, patients present a high prevalence of recurrent and de novo NASH. They also show a high frequence of metabolic disorders. Nevertheless, these alterations seem not to influence patient survival.

Cardiovascular Complications of Chronic Opium Consumption: A Narrative Review Article

2020 ◽  
Author(s):  
Mojtaba ZIAEE ◽  
Reza HAJIZADEH ◽  
Arash KHORRAMI ◽  
Nariman SEPEHRVAND ◽  
Saeideh MOMTAZ ◽  
...  
Keyword(s):  
Cardiovascular Diseases ◽  
Cardiovascular Complications ◽  
Review Article ◽  
High Availability ◽  
Coronary Artery Diseases ◽  
High Prevalence ◽  
The World ◽  
Drugs And Crime ◽  
Opium Use ◽  
Related Mortality

Opiates are the second most prevalent abused illicit substance after cannabis in the world. The latest United Nations Office on Drugs and Crime (UNODC) report estimated 30% increment in opium cultivation worldwide. High prevalence of opium consumption in eastern countries may be due to the high availability and traditional misconceptions. Opium consumption has been linked to hypertension, diabetes mellitus, dyslipidemia, and coronary artery diseases (CAD). In this review, we will review the association between opium use, cardiovascular diseases, and clinical outcomes. The present evidence suggests that chronic opiate consumption may increase the risk of cardiovascular diseases and related mortality.

High prevalence of incidental brain findings in primary dysmenorrhoea

2014 ◽  
Vol 19 (8) ◽  
pp. 1071-1074 ◽  
Author(s):  
W.C. Li ◽  
C.H. Tu ◽  
H.T. Chao ◽  
T.C. Yeh ◽  
L.F. Chen ◽  
...  
Keyword(s):  
Primary Dysmenorrhoea ◽  
High Prevalence

scholarly journals Tinnitus induction in animals and its impact on auditory system structure

2019 ◽  
Author(s):  
Mitra Rezapour ◽  
Abdollah Moossavi
Keyword(s):  
Animal Model ◽  
Animal Models ◽  
Auditory System ◽  
Structural Changes ◽  
Age Groups ◽  
Review Article ◽  
System Structure ◽  
High Prevalence ◽  
Ototoxic Drugs ◽  
External Stimuli

Background and Aim: Tinnitus is a perception of sound in ears or head in the absence of any external stimuli. Despite its high prevalence in various age groups, tinnitus has still no effective treatment because its physiological and patho­logical mechanisms have remained unknown. Since the study of cellular-molecular mechan­isms of tinnitus production and stability in human is not feasible, animal models have been used to shed some light on tinnitus induction and propagation mechanisms. This study revie­wed some of these research studies. The present review article is based on articles published during 1967–2018 in which keywords such as “salicylate,” “noise,” “tinnitus in the animal model,” and “tinnitus mechanism” were used. These articles were searched in databases such as Science Direct, Google Scholar, PubMed, and Scopus. Recent Findings: Despite differences in the mechanisms of tinnitus induction, the structural changes initiated from the cochlea and conti­nued to cortex reflect the extent of the affected regions in the creation, development, and pre­servation of tinnitus. Conclusion: Animal models (exposed to noise or ototoxic drugs such as salicylate) are ideal tools for studying tinnitus and understanding the details of its propagation and unknown mecha­nisms.

scholarly journals The prevalence of delirium in patients in Iran: a systematic review and meta-analysis

2019 ◽  
Vol 14 (4) ◽  
pp. FNL34
Author(s):  
Ebrahim Khalighi ◽  
Asma Tarjoman ◽  
Alireza Abdi ◽  
Milad Borji
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Search Time ◽  
Time Frame ◽  
Review Article ◽  
General Ward ◽  
Hospitalized Patients ◽  
High Prevalence ◽  
General Wards

Aim: The first systematic review and meta analysis investigating the prevalence of delirium in Iran and the importance of delirium in the health status of patients. Method: This study is a review article to determine the overall prevalence of delirium in patients admitted to the hospitals in Iran, with search time frame to 12 October 2000–12 October 2018. The study examined the prevalence of delirium in general wards and ICUs of Iran according to published article in domestic and foreign journals. The methodological quality of the papers was based on a tool used in previous studies. Data was analyzed using comprehensive meta-analysis (CMA) software. Findings: The findings showed the prevalence of delirium in hospitalized patients in Iran is 21.8% (CI: 17.5–27.5%). The prevalence of delirium in hospitalized patients in Iran based on the hospitalization in ICU is 24.7% (CI: 18.1–32.7%) and in the general ward is 17.5% (CI: 13.6–22.3%). Conclusion: Due to the relatively high prevalence of delirium in patients admitted to hospitals in Iran, prevention is necessary to reduce the incidence of delirium.

scholarly journals Prevailing Perceptions and the Growth of Private Label Brands in Africa and Europe: An Overview

2019 ◽  
Vol 11 (5(J)) ◽  
pp. 76-83
Author(s):  
Sbonelo Ndlovu
Keyword(s):  
Recent Literature ◽  
Review Article ◽  
The State ◽  
Private Label ◽  
National Brands ◽  
Clear View ◽  
Customer Perceptions ◽  
Private Label Brands ◽  
Different Parts

This paper reviewed the existing literature in different parts of the continents, focusing specificallyin Africa and Europe, critically reviewing past and recent literature of studies on customers’ perceptionstowards private label brands. Such review article enabled the writer to understand the prevailing state ofprivate label brands across different continents; in the process enabling grocery retailers, marketingpractitioners and academics a clear view of the state of customers’ perceptions around the globe. The resultsfound that the international state of private label brands has somehow improved in some parts of the globe,especially in Europe and Americas, where private label brands have enormously improved customersperceptions of their private label brands and in the process actively competing with national brands for themarket share. Opposing such success, In Africa there seems to be somehow lack of improvement in the earlyperceptions of private label brands in the process not fully challenging national brands. Noticeably, in Africathere seems customers still perceive private label brands as alternatives of national brands in tougheconomic conditions. Hence, grocery retailers need to extensively invest on their private label brands in orderto competitively challenge and change existing customer perceptions. Key investments should be in branding,promoting and educating customers about private label brands.

Phases of Menstrual Cycle : The Ayurveda Perspective

2018 ◽  
Vol 3 (5) ◽  
Author(s):  
Dr. Shridevi T N. ◽  
Dr. Shreevathsa .
Keyword(s):  
Menstrual Cycle ◽  
Menstrual Blood ◽  
Fertile Period ◽  
Menstrual Flow ◽  
Contemporary Science

The menstrual cycle is the cyclical events that occur in the endometrium of uterus to form visible flow of menstrual blood every month. The Artava Pravritti is the menstrual flow which is said to be three to five days as per Ayurveda. The Ritukala is the fertile period of woman’s endometrial cycle. The different phases of menstrual cycle in the contemporary science need to be studied in Ayurveda for similarities if any. The present paper emphasises on the study of day, duration and events of phases of menstrual cycle in Ayurveda with that of contemporary science.

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