scholarly journals AN OBSERVATIONAL STUDY TO EVALUATE VASTRARANJANA IN ARTAVAPAREEKSHA

2021 ◽  
Vol 9 (11) ◽  
pp. 2652-2658
Author(s):  
Devi S Nair ◽  
Nisha Kumari

Objectives: Menstrual problems and infertility are the major problems affecting society nowadays. It can occur due to many reasons namely pathology of Garbhashaya, Artavavaha Dhamani, Dushta Artava etc. For the evalu- ation of structural abnormalities, various technologies like USG, HSG, Hormonal assay etc. are available. But no methods were developed yet to check the purity of Artava. In this background, the Vastraranjana concept men- tioned in the context of Shudha Rakta Lakshana can be considered as a useful tool for diagnosing Artava Dushti. The practicality of this Pareeksha if proved it envisages a new and simple diagnostic tool in Ayurveda. Methods- Menstrual blood samples-stained cotton clothes were washed, and changes were noted. Results- Dushita Artava was found to be causing a stain on the cloth. Conclusion- Changes in the character of Dosha produces Soshana Vidaha Ghanatha etc. of Artava which involve a change in pH, viscosity like elements creating a stain on the cloth. Keywords: Artava Pareeksha, Vastra Ranjana, Menstrual Cycle

Author(s):  
Zhilong Li ◽  
Duo Peng ◽  
Huan Tian ◽  
Jijun Wang ◽  
Yu Xia ◽  
...  

2017 ◽  
Vol 1 (28) ◽  
pp. 661-670
Author(s):  
NASSER NAFAA ABRAHEM ◽  
SAAD HASSAN DREIJ ◽  
Mahdi Saber Al-Deresawi

This study aimed to determine the relationship of  thyroid hormone disturbance and prolactin over production to impact on the menstrual irregularities anovulation .This  study were carried out in Al-Karama teaching hospital and  included (47) primary infertile women, (30 ) of them were with hypothyroidism , the patients aged between (18-40). This study extended from February to June  2017. The hormonal assay of TSH, FT3, FT4 ,FSH , LH and PRL that revealed  :- There were high  significantly (p < 0.01) increased in TSH concentrations , significantly (p < 0.05) decreased in levels of FT3 and  FT4.Gonadotropins hormones recorded significantly ( p <0.05) decreased in levels of FSH and non significantly increased in levels of LH. Prolactin concentrations that obtained revealed to significantly (p < 0.05) increased in patients with hypothyroidism . This study reported there were (70%) of hypothyroidism patients with menstrual disturbance. We concluded , that hypothyroidism and Hyperprolactinemia commonly related and synergized to menstrual irregularities and ovulatory failure. 


2019 ◽  
pp. 1-9 ◽  
Author(s):  
Danielle Bradley ◽  
Erin Landau ◽  
Noreen Jesani ◽  
Brett Mowry ◽  
Kenneth Chui ◽  
...  

2007 ◽  
Vol 35 (4) ◽  
pp. 498-504 ◽  
Author(s):  
S. J. Matzelle ◽  
N. M. Gibbs ◽  
W. Weightman ◽  
M. Sheminant ◽  
R. Rowe ◽  
...  

In an observational study using heparinase-modified thrombelastography, we investigated the percentage of elective cardiothoracic surgical patients receiving low-dose unfractionated heparin (5000 IU 12 hourly subcutaneously) who had a demonstrable systemic heparin effect. Blood samples were obtained at induction from 40 adult elective cardiothoracic surgical patients who had received 5000 IU unfractionated heparin subcutaneously within six hours. Simultaneous kaolin and heparinase-modified thrombelastographies were run on all samples. Fourteen patients (35%; 95% CI: 20 to 50%) had a demonstrable heparin effect(defined as a kaolin thrombelastography R time >25% longer than the heparinase-modified control). Their mean±SD kaolin thrombelastography R time was 13.6±5.9 minutes (normal range 4 to 8 minutes) vs. 7.1±2.0 minutes for the heparinase-modified controls. In 10 patients the thrombelastography R times were >50% longer and in four patients >100% longer, than their respective heparinase-modified controls. In a post hoc analysis, there was little correlation between the extent of the prolongation and patient age (r=0.02), weight (r=-0.31), preoperative creatinine (r=-0.17), or time since administration of heparin (r=0.14). These results indicate that about one third of patients who have received low-dose unfractionated heparin subcutaneously within six hours have a demonstrable heparin effect. The potential for this effect should be considered if central neural blockade is planned.


Author(s):  
Navraj S. Heran ◽  
Stephen J. Hentschel ◽  
Brian D. Toyota

Background:Cerebral vasospasm adversely impacts the outcome of those suffering aneurysmal subarachnoid hemorrhage (SAH). Prediction of vasospasm could improve outcomes. We hypothesized that preclinical vasospasm would be heralded by an increase in cerebral oxygen extractions (AVDO2) which could be detected by jugular bulb oximetry. A pilot study was conducted to address this hypothesis.Methods:Fourteen consenting patients with aneurysmal SAH, undergoing early surgery, were entered into the study. Four patients were withdrawn from the study secondary to failure of catheters or religious belief. At the time of craniotomy, a jugular bulb catheter was placed. Post-operatively, arterial and jugular bulb blood samples were taken every 12 hours to calculate AVDO2. As this was an observational study, no change in management occurred based on measurements.Results:Four of 10 patients had clinical vasospasm. These patients had a significant rise in AVDO2 approximately one day prior to the onset of neurologic deficits (P<0.001). Symptoms resolved along with a significant improvement in AVDO2 on instituting hypertensive, hemo-dilutional, and hypervolemic therapy in these patients. The six patients who did not exhibit clinical vasospasm did not demonstrate significant rise in AVDO2.Conclusion:Jugular bulb oximetry is simple and cost effective. Increases in AVDO2 using this technique were predictive of clinically evident vasospasm in the subsequent hours to days. This investigation supports a larger study to assess the utility of jugular bulb oximetry in predicting vasospasm in aneurysmal SAH.


Reproduction ◽  
2002 ◽  
pp. 259-265 ◽  
Author(s):  
◽  
Y Xia ◽  
T O'Shea ◽  
S Hayward ◽  
AE O'Connor ◽  
...  

The aim of this study was to investigate the changes in follistatin, an activin binding protein, during the oestrous cycle, gestation and parturition in ewes using a radioimmunoassay for total follistatin, which uses dissociating reagents to remove the interference of activin. Follistatin concentrations remained unchanged (2.7 +/- 0.2 ng ml(-1)) during the oestrous cycle and decreased as pregnancy progressed. Follistatin concentrations in allantoic fluid also decreased during gestation, whereas in amniotic fluid follistatin concentrations reached a peak at day 75 of gestation (9.8 ng ml(-1)) and had decreased to 4.4 ng ml(-1) at day 140. Follistatin concentrations in fetal blood (7.0 +/- 0.5 ng ml(-1)) did not change from day 50 to day 140 of gestation but were significantly higher than in matched maternal samples (3.1 +/- 0.3 ng ml(-1)). Circulating follistatin in ewes was significantly increased on the day of parturition (5.6 +/- 0.6 ng ml(-1)) compared with the days before parturition (2.7 +/- 0.4 ng ml(-1)), but had decreased by day 2 after birth. Blood samples from newborn lambs showed that plasma follistatin concentration (13.4 +/- 2.3 ng ml(-1)) was significantly higher than that of the mothers and remained high for at least 7 days after birth. These data support previous studies of the human menstrual cycle indicating that follistatin is not an endocrine signal from the ovary; however, in contrast to human pregnancies, follistatin concentrations in sheep decreased and become high only after or during parturition. This difference observed between species may reflect different physiological effects of follistatin or may be the result of measurement of different isoforms.


2017 ◽  
Vol 99 ◽  
pp. 21-27 ◽  
Author(s):  
Michael P. Hengartner ◽  
Tillmann H.C. Kruger ◽  
Kirsten Geraedts ◽  
Enrico Tronci ◽  
Toni Mancini ◽  
...  

1987 ◽  
Vol 113 (2) ◽  
pp. 291-295 ◽  
Author(s):  
M. C. P. Rees ◽  
V. Di Marzo ◽  
J. R. Tippins ◽  
H. R. Morris ◽  
A. C. Turnbull

ABSTRACT Endometrium and myometrium were collected at hysterectomy from 21 women with measured menstrual blood loss. Eight women complained of dysmenorrhoea and the remaining 13 had pain-free periods. Specimens were obtained throughout the menstrual cycle (menstrual, n = 5; follicular, n = 3; early luteal, n = 3; mid-luteal, n = 5; late luteal, n = 4). Leukotriene C4, leukotriene D4 and leukotriene E4 release were examined using a short-term incubation technique. Endometrial leukotriene release, which was always significantly greater than myometrial release, changed throughout the menstrual cycle and the highest concentrations were found during menstruation. Endometrial, but not myometrial, leukotriene concentrations were significantly higher in tissues obtained from women with a complaint of dysmenorrhoea compared with those in tissue from pain-free women. No correlation was found between leukotriene release in either endometrium or myometrium and menstrual blood loss (range 15–457 ml). J. Endocr. (1987) 113, 291–295


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