scholarly journals Application of the topological gradient method to tomography

2010 ◽  
Vol Volume 13 - 2010 - Special... ◽  
Author(s):  
D. Auroux ◽  
L. Jaafar-Belaid ◽  
B. Rjaibi

International audience A new method for parallel beam tomography is proposed. This method is based on the topological gradient approach. The use of the topological asymptotic analysis for detecting the main edges of the data allows us to filter the noise while inverting the Radon transform. Experimental results obtained on noisy data illustrate the efficiency of this promising approach in the case of Magnetic Resonance Imaging. We also study the sensitivity of the algorithm with respect to several regularization and weight parameters. Une nouvelle méthode de reconstruction pour la tomographie par faisceaux parallèles est proposée. Cette méthode est basée sur l’approche du gradient topologique. En détectant les contours sur les données grâce à l’analyse asymptotique topologique, il est possible de filtrer le bruit dans le processus d’inversion de la transformée de Radon. Des résultats expérimentaux obtenus sur des données bruitées illustrent les possibilités de cette approche prometteuse dans le domaine de traitement d’images IRM. Nous étudions également la sensibilité de l’algorithme par rapport aux différents paramètres de régularisation et pondération.

2002 ◽  
Vol 2 ◽  
pp. 1803-1807
Author(s):  
Daniel Caggiano ◽  
Mateus Joffily

The fourth fMRI Experience meeting was held at the Bethesda, Maryland campus of the National Institutes of Health on May 13thand 14th, 2002. The purpose of the meeting was to provide a platform for students working with functional magnetic resonance imaging (fMRI) to present their research to an international audience of peers. This year’s meeting featured special lectures from Dr. Leslie Ungerleider (“Imaging Mechanisms of Visual Attention”) and Dr. Daniel Weinberger (“Genetic Variation and fMRI Response”).


Author(s):  
Alan P. Koretsky ◽  
Afonso Costa e Silva ◽  
Yi-Jen Lin

Magnetic resonance imaging (MRI) has become established as an important imaging modality for the clinical management of disease. This is primarily due to the great tissue contrast inherent in magnetic resonance images of normal and diseased organs. Due to the wide availability of high field magnets and the ability to generate large and rapidly switched magnetic field gradients there is growing interest in applying high resolution MRI to obtain microscopic information. This symposium on MRI microscopy highlights new developments that are leading to increased resolution. The application of high resolution MRI to significant problems in developmental biology and cancer biology will illustrate the potential of these techniques.In combination with a growing interest in obtaining high resolution MRI there is also a growing interest in obtaining functional information from MRI. The great success of MRI in clinical applications is due to the inherent contrast obtained from different tissues leading to anatomical information.


1998 ◽  
Vol 41 (3) ◽  
pp. 538-548 ◽  
Author(s):  
Sean C. Huckins ◽  
Christopher W. Turner ◽  
Karen A. Doherty ◽  
Michael M. Fonte ◽  
Nikolaus M. Szeverenyi

Functional Magnetic Resonance Imaging (fMRI) holds exciting potential as a research and clinical tool for exploring the human auditory system. This noninvasive technique allows the measurement of discrete changes in cerebral cortical blood flow in response to sensory stimuli, allowing determination of precise neuroanatomical locations of the underlying brain parenchymal activity. Application of fMRI in auditory research, however, has been limited. One problem is that fMRI utilizing echo-planar imaging technology (EPI) generates intense noise that could potentially affect the results of auditory experiments. Also, issues relating to the reliability of fMRI for listeners with normal hearing need to be resolved before this technique can be used to study listeners with hearing loss. This preliminary study examines the feasibility of using fMRI in auditory research by performing a simple set of experiments to test the reliability of scanning parameters that use a high resolution and high signal-to-noise ratio unlike that presently reported in the literature. We used consonant-vowel (CV) speech stimuli to investigate whether or not we could observe reproducible and consistent changes in cortical blood flow in listeners during a single scanning session, across more than one scanning session, and in more than one listener. In addition, we wanted to determine if there were differences between CV speech and nonspeech complex stimuli across listeners. Our study shows reproducibility within and across listeners for CV speech stimuli. Results were reproducible for CV speech stimuli within fMRI scanning sessions for 5 out of 9 listeners and were reproducible for 6 out of 8 listeners across fMRI scanning sessions. Results of nonspeech complex stimuli across listeners showed activity in 4 out of 9 individuals tested.


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