scholarly journals PHYTOCHEMICAL SCREENING AND ANTHELMINTIC ACTIVITY OF LEAFAND SEED EXTRACT OF CASSIA OCCIDENTELIS L.

2021 ◽  
Author(s):  
Afsheen KHAN
Keyword(s):  
Anthelmintic Activity ◽  
Seed Extract ◽  
Phytochemical Screening

Phytochemical characterization of Caraway (Carum carvi) seed extract and its use as a potent medicinal agent

2021 ◽  
Vol 16 (10) ◽  
pp. 102-110
Author(s):  
Vivek Chauhan ◽  
Sunita Devi ◽  
Sonaxi Sharma ◽  
Shamsher S. Kanwar
Keyword(s):  
Staphylococcus Epidermidis ◽  
Arable Land ◽  
Seed Extract ◽  
Phytochemical Analysis ◽  
Phytochemical Screening ◽  
Food Industries ◽  
Carum Carvi ◽  
Medicinal Properties ◽  
The Village

Carum carvi (Caraway) is a member of Apiaceae family which originated in Asia. Due to its economic importance, it is widely cultivated. Caraway is the only annual species, commonly present in arable land, moist meadows and on low lands to mountains. Caraway has different applications in pharmaceutical and food industries. Phytochemical screening of different medicinal plants is helpful in identifying new sources of industrially and therapeutically important compounds. In this study, Caraway obtained from forest surrounding the village Goherman, Lahaul and Spiti, Himachal Pradesh (India) was used. Seed extract of caraway extracted in methanol (MSE) and distilled water (WSE) was used for phytochemical analysis to determine the constituents of caraway seeds. Further, caraway seeds extract was checked for antibacterial activity [Staphylococcus aureus (ATCC 6538), Salmonella typhimurium (NCTC 74), Escherichia coli (ATCC 25922) and Staphylococcus epidermidis (ATCC 12228)], antioxidant activity and acid neutralizing activity. After analysing the results, it can be said that caraway seeds possess many medicinal properties and it can be used in enhancing human health.

scholarly journals Phytochemical Analysis and In-Vitro Effects of Ethanolic Tamarindus Indica Seed Extract on Snake Venom

2017 ◽  
Vol 16 (1) ◽  
Author(s):  
Soraya Ismail ◽  
Nur Farhana Azmi ◽  
Khin Maung Maung ◽  
Pakeer Oothuman
Keyword(s):  
Snake Venom ◽  
Seed Extract ◽  
Tamarindus Indica ◽  
Phytochemical Screening ◽  
Snake Species ◽  
Hydrolysable Tannins ◽  
Group 2 ◽  
In Vitro Effects ◽  
Group 1

Introduction: Snakebite has been categorised as a ‘neglected tropical disease’ by WHO in 2009 and it affects mainly the poorer countries like Africa and Asia. The standard treatment for snake envenomation is the anti-snake venom medication which can be very expensive, not readily available and specific against a snake species. This study was conducted to screen the phytochemical compounds of Tamarindus indica seed extract (TSE) and its in-vitro effects on snake venom of three snake species; namely Daboia russelli, Naja kaouthia and Ophiophagus hannah. Materials and method: Ethanolic Soxhlet extract of TSE was used. Phytochemical screening analysing for saponins, alkaloids, flavanoids, anthraquinone derivatives, arthraquinone glycosides, phenolic compounds, tannins, terpenoids, sterol and volatile oils were carried out. In-vitro enzymatic inhibition study on venom enzymes namely phospholipase A2 (PLA2), proteinase and phosphomonoesterase (PME) were studied by measuring the absorbance using the spectrophotometer. There were two main groups; Group 1: venom only; and Group 2: venom with TSE. The mean triplicate determination of venom enzyme activity post-exposure to TSE from Group 2 was taken and analysed against 100% venom enzyme activity from Group 1. Results: Phytochemical screening showed that the TSE has (+++) phenolics and (+++) hydrolysable tannins. TSE significantly reduced all venom enzymatic activities i.e. PLA2, proteinase and PME from the three snake species at 925 nm, 280 nm and 400 nm, respectively. SDS-PAGE experiment showed the disruption of venom protein bands from all three snake species when venom was exposed to 4.76 µg TSE. Conclusion: Ethanolic TSE contains mainly phenolics and hydrolysable tannins which can reduce the snake venom enzymatic activities. This is possibly due to the formation of tannin-protein complex rendering the venom less potent.

Phytochemical screening and anthelmintic activity of Artocarpus altilis extract

2021 ◽  
Vol 14 (2) ◽  
pp. 640-644
Author(s):  
Kunal Bhattacharya ◽  
Atanu Bhattacharjee ◽  
Nongmaithem Randhoni Chanu ◽  
Biplab Kumar Dey ◽  
Chanam Melody Devi
Keyword(s):  
Anthelmintic Activity ◽  
Phytochemical Screening ◽  
Artocarpus Altilis

Phytochemical Screening and Anti-Diabetic Efficacy of O. Sanctum Seed Extract on Streptozotocin Induced Diabetic Rats

2017 ◽  
Vol 54 (3) ◽  
pp. 336
Author(s):  
Kavitha K. ◽  
Ponne S.
Keyword(s):  
Body Weight ◽  
Digestive Enzymes ◽  
Fasting Blood Glucose ◽  
Inhibitory Effect ◽  
Diabetic Rats ◽  
Seed Extract ◽  
Phytochemical Screening ◽  
Weight Changes

The present study was designed to assess the in vitro and in vivo anti-diabetic efficacy of <em>O. sanctum</em> seed and its phytochemical screening. In vitro inhibitory effect on carbohydrate digestive enzymes like α-amylase and α-glucosidase and in vivo parameters such as fasting blood glucose and body weight changes were studied, a potent inhibitory effect was observed on activities of digestive enzymes and a marked decrease in the glucose level in the <em>O. sanctum</em> seed extract treated streptozotocin induced diabetic rats was noted. Further a marked reduction in body weight was also observed.

scholarly journals Phytochemical screening and in vitro anthelmintic activity of methanol extract of Terminalia citrina leaves

2015 ◽  
Vol 5 ◽  
pp. S166-S168 ◽  
Author(s):  
Narhari Das ◽  
Durajan Goshwami ◽  
Md. Sharif Hasan ◽  
Sheikh Zahir Raihan ◽  
Nirmal Kumar Subedi
Keyword(s):  
Methanol Extract ◽  
Anthelmintic Activity ◽  
Phytochemical Screening

scholarly journals PRELIMINARY PHYTOCHEMICAL SCREENING AND IN VITRO ANTHELMINTIC ACTIVITY OF ETHANOLIC EXTRACT OF LEAF RACHIS OF AZADIRACHTA INDICA Linn. (NEEM)

2017 ◽  
Vol 03 (01) ◽  
pp. 8-12
Author(s):  
Gavalapu Venkateswara Rao ◽  
Abhinav kanagarla ◽  
Allamraju Satyakeertana ◽  
Vinukonda Alekhya ◽  
Dammu Saipriya ◽  
...  
Keyword(s):  
Azadirachta Indica ◽  
Anthelmintic Activity ◽  
Ethanolic Extract ◽  
Phytochemical Screening

scholarly journals SKRINING FITOKIMIA DAN UJI AKTIVITAS ANTIOKSIDAN EKSTRAK BIJI ADAS (Foeniculum vulgare) MENGGUNAKAN METODE DPPH

2013 ◽  
Vol 13 (2) ◽  
pp. 110
Author(s):  
Idza N Sastrawan ◽  
Meiske Sangi ◽  
Vanda Kamu
Keyword(s):  
Antioxidant Activity ◽  
Natural Antioxidants ◽  
Seed Extract ◽  
Phytochemical Screening ◽  
Activity Assay ◽  
Foeniculum Vulgare ◽  
Fecl3 Solution ◽  
Dpph Method ◽  
Chemical Content ◽  
Keywords Antioxidants

SKRINING FITOKIMIA DAN UJI AKTIVITAS ANTIOKSIDAN EKSTRAK BIJI ADAS (Foeniculum vulgare) MENGGUNAKAN METODE DPPH ABSTRAK Telah dilakukan penelitian tentang skrining fitokimia dan uji aktivitas antioksidan ekstrak biji adas. Tujuan dari penelitian ini yaitu melakukan skrining fitokimia untuk mengetahui kandungan senyawa alkaloid, triterpenoid dan steroid, flavonoid, tannin, saponin dan menetukan aktivitas antioksidan dari ekstrak biji adas. Skrining Fitokimia untuk alkaloid ditentukan dengan menggunakan pereaksi Mayer, Dregendorff, Wagner. Triterpenoid dan steroid ditentukan menggunakan Mg bubuk. Senyawa tannin ditentukan dengan larutan FeCl3 1%. Senyawa saponin ditentukan menggunakan aquades. Ekstrak biji adas diperoleh dengan metode soxhletasi menggunakan pelarut petroleum eter dan uji aktivitas antioksidan menggunakan metode               1-1-difenil-2-pikrihidrazil (DPPH).  Hasil penelitian menunjukan kandungan senyawa kimia biji adas positive mengandung senyawa falvonoid, tannin dan saponin, sedangkan untuk senyawa alkaloid, triterpenoid dan steroid memberikan hasil yang negatif. Aktivitas antioksidan dengan 1000; 2000; 3000; 4000; 5000 ppm,  memberikan hasil berturut-turut yaitu 48.99 %, 33.92 %, 5.93 %, 21.23 %, 6.40 %. Aktivitas antioksidan biji adas tertinggi terdapat pada konsentrasi    1000 ppm dengan hasil 48.99 %. Biji adas memiliki persen aktivitas antioksidan yang baik, sehingga dapat didigunakan sebagai salah satu sumber antioksidan alami.   Kata kunci : Antioksidan, Biji adas, DPPH phytochemical screening and antioxidant activity testing of fennel seed extract (foeniculum vulgare) Using the dpph method Abstract Has done research on phytochemical screening and testing fennel seed extract antioxidant activity. The purpose of this study is to determine the phytochemical screening compounds content of alkaloids, triterpenoids and steroids, flavonoids, tannins, saponins and determine the antioxidant activity of extracts of fennel seeds. Phytochemical screening for alkaloids was determined using reagent Mayer, Dregendorff, Wagner. Triterpenoids and steroids were determined using Mg powder. Tannin compounds determined with 1% FeCl3 solution and saponin determined using distilled water. Fennel seed extract obtained by the method soxhletasi using petroleum ether solvent and antioxidant activity assay using method 1-1-diphenyl-2-pikrihidrazil (DPPH). Research has been done showing the chemical content of fennel seeds contain compounds falvonoid positive , tannins and saponins . Antioxidant activity with 1000 ppm , 2000 ppm,    3000 ppm , 4000 ppm , 5000 ppm , respectively yield is 48.99 % , 33.92 % , 5.93 % , 21.23 %, 6.40 %. The highest antioxidant activity of fennel seeds contained 1000 ppm with 48.99 % result. Fennel seeds have a good percent antioxidant activity , so it can didigunakan as a source of natural antioxidants. Keywords : Antioxidants, Fennel seeds, DPPH

scholarly journals Phytochemical Study and Anthelmintic Activity of Nine Congolese Medicinal Plants

2021 ◽  
pp. 63-76
Author(s):  
Mikala Grâce Raycélia Merveille ◽  
Nkounkou Loumpangou Célestine ◽  
Kadja Amani Brice ◽  
Mamyrbekova-Békro Janat Akhanovna ◽  
Békro Yves-Alain ◽  
...  
Keyword(s):  
Vitamin C ◽  
Public Health Problem ◽  
Anthelmintic Activity ◽  
Antioxidant Potential ◽  
Aqueous Extracts ◽  
Phytochemical Screening ◽  
Dpph Radical ◽  
Piper Guineense ◽  
Phytochemical Study ◽  
Intestinal Parasitosis

Background: Despite advances in hygiene and preventive medicine, parasitic diseases, particularly digestive parasitosis, remain a public health problem in tropical countries. Elaborate the ethnobotanical survey carried out in Brazzaville - Congo, 21 plants (divided into 20 families, 20 genera) were identified, among them 9 were selected for this study. These were: Ageratum conyzoides (L.) L., Rauvolfia mannii Stapf, Aloe buettneri A. Berger, Garcinia kola Heckel, Piper guineense Schumach & Thonn., Aframomum alboviolaceum (Ridl.) K. Schum., Plagiostyles africana (Müll .Arg.) Prain, Morinda lucida Benth, Cogniauxia podoleana Baill. Materials and Methods: The in vitro evaluation of the anthelmintic activity of the aqueous extracts of these 9 plants was determined at concentrations of 10, 25 and 50 mg/mL against Lumbricus terrestris used as animal support in comparison to the Mebendazole (20 mg/mL). The phytochemical screening realized by TLC to detect phytochemical families in plant, also, the antioxidant potential with DPPH radical was determined by UV-Visible spectrophometry in comparison to the Vitamin C. Results: Thus, P. guineense, A. conyzoides and A. alboviolaceum are those which presented significant vermicidal effect, after Mebendazole. Phytochemical screening into TLC revealed the co-presence of alkaloids, coumarins, flavonoids, tannins, sterols and terpenes.The antioxidant potential of the aqueous extracts of these different plants in comparison to vitamin C, has shown that the species A. Buettineri and A. alboviolaceum presented the best potential compared to 7 other species studied, with the  concentration  needed to  reduce 50% of the DPPH radical (CR50)  respectively 0.096 mg/mL for A. Buettineri, 0.098 mg/mL for A. alboviolaceum Berger and 0.015 mg/mL for vitamin C. Conclusion: There is modern drugs against intestinal worms, it is necessary to identify the plants with anthelmintic activity, to determine phytochemical compounds that would be responsible for their use by traditional healers to treat the intestinal parasitosis.

scholarly journals In vitro thrombolytic, anthelmintic, anti-oxidant and cytotoxic activity with phytochemical screening of methanolic extract of Xanthium indicum leaves

2015 ◽  
Vol 10 (4) ◽  
pp. 854 ◽  
Author(s):  
Antara Ghosh ◽  
Sujan Banik ◽  
Md. Ariful Islam
Keyword(s):  
Cytotoxic Activity ◽  
Methanolic Extract ◽  
Radical Scavenging ◽  
Anthelmintic Activity ◽  
Positive Control ◽  
Clot Lysis ◽  
Total Phenolic ◽  
Phytochemical Screening ◽  
Anti Oxidant

<p class="Abstract"><em>Xanthium indicum</em> is an important medicinal plant traditionally used in Bangladesh as a folkloric treatment. The current study was undertaken to evaluate thrombolytic, anthelmintic, anti-oxidant, cytotoxic properties with phytochemical screening of methanolic extract of <em>X. indicum</em> leaves. The analysis of phytochemical screening confirmed the existence of phytosetrols and diterpenes. In thrombolytic assay, a significant clot lysis was observed at four concentrations of plant extract compare to the positive control streptokinase (30,000 IU, 15,000 IU) and negative control normal saline. The extract revealed potent anthelmintic activity at different concentrations. In anti-oxidant activity evaluation by two potential experiments namely total phenolic content determination and free radical scavenging assay by 2, 2-diphenylpicrylhydrazyl (DPPH), the leaves extract possess good anti-oxidant property. In the brine shrimp lethality bioassay, the crude extract showed potent (LC<sub>50</sub> 1.3 μg/mL) cytotoxic activity compare to the vincristine sulfate as a positive control (LC<sub>50</sub> 0.8 μg/mL). </p><p> </p>

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