scholarly journals A Case of Medallion-Like Dermal Dendrocyte Hamartoma with a Distinctive Size and Vascular Component

2013 ◽  
Vol 4 (4) ◽  
Author(s):  
Didem Dincer
Keyword(s):  
Vascular Component ◽  
Dermal Dendrocyte

The Vascular Component of Alzheimer’s Disease

2014 ◽  
Vol 11 (2) ◽  
pp. 168-176 ◽  
Author(s):  
Dafin Muresanu ◽  
Aurel Popa-Wagner ◽  
Adina Stan ◽  
Ana-Maria Buga ◽  
Bogdan Popescu
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Vascular Component

Anatomy, Physiology and Pathophysiology of Haemorrhoids

2020 ◽  
Vol 15 ◽  
Author(s):  
Francesco Pata ◽  
Alessandro Sgrò ◽  
Francesco Ferrara ◽  
Vincenzo Vigorita ◽  
Gaetano Gallo ◽  
...  
Keyword(s):  
Anal Canal ◽  
Dentate Line ◽  
Cochrane Library ◽  
Systematic Research ◽  
Literature Searching ◽  
Patient History ◽  
Haemorrhoidal Disease ◽  
Faecal Continence ◽  
Vascular Component ◽  
Key Events

Background: Haemorrhoidal disease (HD) is a frequent anal disorder and one of the most common findings identified at colorectal clinic. This article aims to provide an overview of the anatomy, physiology and pathophysiology of haemorrhoids and haemorrhoidal disease. Introduction: Internal haemorrhoids are vascular cushions located in the anal canal, above the dentate line and covered by columnar epithelium. They contribute to the faecal continence and to the sensitivity of the anal canal. The enlargement and/or sliding of haemorrhoidal tissue produce symptoms and complications, the so-called haemorrhoidal disease. Method: A systematic research was realized, looking at the best evidence in literature , searching PubMed, Embase, Cochrane library and most renowned text of colorectal surgery from January 1980 to January 2020. Result: Aetiology and pathophysiology of HD are still controversial, but multifactorial. Disruption of stromal scaffolding, enlargement of vascular component, elevated anal pressure and rectal redundancy represent key events in the development and complications of the disease. Local inflammation may play also a role. Goligher’s classification remains the most widely used. A careful patient history and examination are paramount to diagnose HD, excluding other anal or colonic pathologies. Conclusion: Several aspects of etiopathogenesis and pathophysiology remain controversial. Further studies are needed to obtain a better understanding of the disease.

scholarly journals Non-productive angiogenesis disassembles Aß plaque-associated blood vessels

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Maria I. Alvarez-Vergara ◽  
Alicia E. Rosales-Nieves ◽  
Rosana March-Diaz ◽  
Guiomar Rodriguez-Perinan ◽  
Nieves Lara-Ureña ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Blood Vessels ◽  
Molecular Signature ◽  
Loss Of Function ◽  
Local Loss ◽  
Microglial Phagocytosis ◽  
Vascular Phenotype ◽  
Cerebral Microvasculature ◽  
Vascular Component

AbstractThe human Alzheimer’s disease (AD) brain accumulates angiogenic markers but paradoxically, the cerebral microvasculature is reduced around Aß plaques. Here we demonstrate that angiogenesis is started near Aß plaques in both AD mouse models and human AD samples. However, endothelial cells express the molecular signature of non-productive angiogenesis (NPA) and accumulate, around Aß plaques, a tip cell marker and IB4 reactive vascular anomalies with reduced NOTCH activity. Notably, NPA induction by endothelial loss of presenilin, whose mutations cause familial AD and which activity has been shown to decrease with age, produced a similar vascular phenotype in the absence of Aß pathology. We also show that Aß plaque-associated NPA locally disassembles blood vessels, leaving behind vascular scars, and that microglial phagocytosis contributes to the local loss of endothelial cells. These results define the role of NPA and microglia in local blood vessel disassembly and highlight the vascular component of presenilin loss of function in AD.

P3-354: Removal of agonistic autoantibodies (agAAB) against adrenoceptors (AR) in patients with Alzheimer's disease / Alzheimer's disease with a vascular component (AD/VD)

2012 ◽  
Vol 8 (4S_Part_16) ◽  
pp. P581-P581
Author(s):  
Elisabeth Steinhagen-Thiessen ◽  
Rudolf Kunze ◽  
Carola Jonatat ◽  
Ursula Kassner ◽  
Imke Decius ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Vascular Component ◽  
Agonistic Autoantibodies

Facial Temperature in Migraine, Tension-Vascular and Tension Headache

Cephalalgia ◽  
1984 ◽  
Vol 4 (3) ◽  
pp. 149-158 ◽  
Author(s):  
PD Drummond ◽  
JW Lance
Keyword(s):  
Clinical Features ◽  
Anterior Part ◽  
Superficial Temporal Artery ◽  
Tension Headache ◽  
Temporal Artery ◽  
Vascular Compression ◽  
Vascular Changes ◽  
Vascular Component ◽  
The Relationship ◽  
Common Carotid Arteries

The relationship between clinical features and changes in the extracranial circulation was studied during 209 separate attacks of headache affecting the anterior part of the head. Extracranial vascular changes were assessed thermographically and by the change in headache intensity when pressure was applied over the superficial temporal and common carotid arteries. In unilateral headaches, increased heat loss from the affected frontotemporal region was observed most frequently in attacks which were temporarily relieved by compression to the superficial temporal artery; thermographic asymmetry disappeared as the headache abated. Although such headaches were associated more frequently with migrainous features than attacks which did not respond to arterial compression, many headaches with clinical features of migraine had no vascular component detectable by thermography or vascular compression. Furthermore, the response to arterial compression was not consistent from one headache to another in the same patient. It was concluded that extracranial vascular changes recur intermittently in headache-prone patients, depending on the severity of pain and association with other features commonly regarded as migrainous. However, there was no clear demarcation point between entities diagnosed clinically as “migraine” and “tension headache”.

Searching for the Vascular Component of the Arterial Baroreflex

2004 ◽  
Vol 4 (2) ◽  
pp. 155-162 ◽  
Author(s):  
Richard L. Hughson ◽  
Deborah D. O'Leary ◽  
J. Kevin Shoemaker ◽  
Der Chyan Lin ◽  
Zbigniew L. Topor ◽  
...  
Keyword(s):  
Arterial Baroreflex ◽  
Vascular Component

scholarly journals BIOENERGY ASPECTS OF FUNCTIONING OF VENOUS WALL COMPONENTS (DEMONSTRATION MATERIALS OF STUDENTS AND YOUNG SCIENTISTS)

2021 ◽  
Vol 1 (4) ◽  
Author(s):  
Mykhailo Lebedyuk ◽  
Vasily Bocharov ◽  
Veronika Bocharova ◽  
Ivanna Zarychniak ◽  
Аnastasia Kovalenok
Keyword(s):  
Extracellular Matrix ◽  
Cell Function ◽  
Vascular Wall ◽  
Vascular Component ◽  
The Subject ◽  
Wall Components ◽  
Venous Wall

The subject of the study – the wall of the venous vessels of the skin. The purpose of the work is to provide demonstration and text materials of the significance of bioenergetic mechanisms of vascular wall components. The vascular component is an integral part of the pathogenesis of most dermatoses. At the same time, the bioenergetic aspects of cell function and the extracellular matrix of the vascular wall, especially venous ones, are still insufficiently taken into account, as they are the most vulnerable to inflammatory dermatoses.Key words: vascular wall components, demonstration materials.

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