scholarly journals Antibiotic resistance profiles of endotracheal aspirates in intensive care unit patients

2019 ◽  
Vol 10 (2) ◽  
Author(s):  
Özlem Koca
Keyword(s):  
Intensive Care Unit ◽  
Antibiotic Resistance ◽  
Intensive Care

scholarly journals CHARACTERISTICS OF ANTIBIOTIC RESISTANCE OF BACTERIA ISOLATED FROM INFANTS – PATIENTS OF NATIONAL HOSPITAL PEDIATRICS HANOI, VIETNAM

2017 ◽  
pp. 51-53
Author(s):  
T.F. Stepanova ◽  
L.V. Kataeva ◽  
A.P. Rebeshchenko ◽  
Le Thanh Hai ◽  
Khu Thi Khanh Dung ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Antibiotic Resistance ◽  
Intensive Care ◽  
High Resistance ◽  
Gram Negative Bacteria ◽  
National Hospital ◽  
Gram Negative ◽  
Resistance To Antibiotics ◽  
Pure Block ◽  
Carbapenem Antibiotic

The results of studies of resistance to antibiotics microflora isolated from mucous pharynx and rectum of patients intensive care unit newborns of National Hospital of Pediatrics, Hanoi are presented. It is shown that gram-negative bacteria isolated from children have a high resistance to penicillins, cephalosporins and carbapenem. Antibiotic resistance of bacteria isolated from children receiving treatment in «pure» block did not differ from sustainability of the strains, selected from children in «dirty» block.

scholarly journals Genotyping of Different Pseudomonas Aeruginosa Morphotypes Arising from the Lower Respiratory Tract of a Patient Taken to an Intensive Care Unit

2008 ◽  
Vol 21 (4) ◽  
pp. 941-947 ◽  
Author(s):  
L. Putignani ◽  
R. Sessa ◽  
A. Petrucca ◽  
C. Manfredini ◽  
L. Coltella ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Pseudomonas Aeruginosa ◽  
Antibiotic Resistance ◽  
Intensive Care ◽  
Respiratory Tract ◽  
Lower Respiratory Tract ◽  
Opportunistic Pathogen ◽  
Growth Media ◽  
Environmental Bacterium ◽  
Genotypic Analysis

Pseudomonas aeruginosa is an opportunistic pathogen and an ubiquitous environmental bacterium. Fifty-seven days after hospitalization, we isolated three distinct P. aeruginosa morphotypes (smooth, rough and mucoid) from the lower respiratory tract of a patient admitted to a Cardiology Intensive Care Unit (ICU). Moreover, a group of nine colony variants, arising from the three P. aeruginosa isolates growing in laboratory growth media, were also isolated. The resulting 12 isolates were characterised for antibiotic resistance profile and subjected to genotypic analysis by fluorescent-Amplified Fragment Length Polymorphism (f-AFLP) and automated repetitive extragenic palindromic-PCR (rep-PCR) fingerprinting. The three smooth, rough and mucoid morphotypes presented different antibiotic resistance profiles and genotyping analysis showed that they belonged to distinct clones, indicating that at day 57 after the admission the patient was simultaneously colonized by three distinct P. aeruginosa isolates. On the other hand, the nine colony variants presented heterogeneous antibiotic resistance profiles and clustered together with the three parental isolates. The understanding of the link between genotype plasticity and antibiotic resistance may contribute to improving our knowledge of this life-threatening pathogen.

scholarly journals Lack of Association between Hypermutation and Antibiotic Resistance Development in Pseudomonas aeruginosa Isolates from Intensive Care Unit Patients

2004 ◽  
Vol 48 (9) ◽  
pp. 3573-3575 ◽  
Author(s):  
Olivia Gutiérrez ◽  
Carlos Juan ◽  
José L. Pérez ◽  
Antonio Oliver
Keyword(s):  
Cystic Fibrosis ◽  
Intensive Care Unit ◽  
Pseudomonas Aeruginosa ◽  
Antibiotic Resistance ◽  
Intensive Care ◽  
Large Collection ◽  
Resistance Development ◽  
Icu Patients

ABSTRACT Hypermutation is a common feature of Pseudomonas aeruginosa isolates from chronically infected cystic fibrosis patients that is linked with antibiotic resistance development. In this work, using a large collection of sequential P. aeruginosa isolates from ICU patients, we found that despite the fact that mutational antibiotic resistance development is a frequent outcome, the prevalence of hypermutable strains is low (found in isolates from only 1 of 103 patients) and there is no evidence of coselection of the hypermutable and antibiotic resistance phenotypes.

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