scholarly journals Correlation of SOX2 expression with clinicopathologic parameters in larynx squamous cell carcinoma

2021 ◽  
Vol 12 (09) ◽  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Sox2 Expression ◽  
Clinicopathologic Parameters ◽  
Larynx Squamous Cell Carcinoma

scholarly journals Correlation of alterations in the KEAP1 / CUL3 / NFE2L2 pathway with radiation failure in larynx squamous cell carcinoma

2021 ◽  
Author(s):  
Siddharth Sheth ◽  
Douglas R. Farquhar ◽  
Travis P. Schrank ◽  
Wesley Stepp ◽  
Angela Mazul ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Larynx Squamous Cell Carcinoma

Pathologic Determination of Multifocality in pT1a1 Squamous Cell Carcinoma of the Cervix: A Retrospective Analysis

2021 ◽  
pp. 106689692199072
Author(s):  
Jingjing Hu ◽  
Kojo R. Rawish ◽  
Mariah Leivo ◽  
Dennis Adams ◽  
Somaye Y. Zare ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Residual Disease ◽  
Cervical Squamous Cell Carcinoma ◽  
Tnm Staging ◽  
Stromal Invasion ◽  
Lateral Extent ◽  
Clinicopathologic Parameters

When more than one focus of stromal invasion is present in a superficially invasive cervical squamous cell carcinoma (SCC), determination of the tumoral lateral extent/horizontal extension, and hence tumor-nodes-metastases (TNM) staging, can be problematic. In recent years, a diagnostic approach to distinguish multifocal pT1a1 from pT1b cases has gained increased attention. These criteria call for classifying SCC as multifocal when invasive foci are separated by blocks of uninvolved cervical tissues, and/or are located on separated cervical lips in a tumor that is discontinuous, and/or are situated far apart (≥2 mm) from each other. In this study, we assess our experience with multifocal stage pT1a1 cervical SCC that was retrospectively classified as such using these criteria. Slides from the loop electrosurgical excision or conization specimens, comprising 212 pT1a1, 173 pT1a2, and 206 pT1b cases, were reviewed. Twenty-four (11%) of the 212 pT1a1 cases were classified as multifocal after review. The 24 multifocal pT1a1 cases were compared with the 188 unifocal pT1a1 cases regarding a variety of clinicopathologic parameters. Notably, these 2 groups showed no significant differences regarding all parameters that were evaluated, including patient age, recurrence rate, primary tumoral features in the primary excision specimen (rate of positive margins, median depth of stromal invasion, frequency of lymphovascular invasion), and frequency of residual disease in additional excisions. In summary, we demonstrate comparably favorable patient outcomes in both unifocal and multifocal cases of pT1a1 SCC of the cervix, and, accordingly, we conclusively affirm the validity of the aforementioned criteria for establishing multifocality.

XPD and ERCC1 polymorphisms of the nucleotide excision repair pathway in outcome of larynx squamous cell carcinoma patients.

2016 ◽  
Vol 34 (15_suppl) ◽  
pp. e17523-e17523
Author(s):  
Carla Tyene Nakata ◽  
Ericka Francislaine Dias Costa ◽  
Bruno De Araujo Lima Franca ◽  
Leisa Lopes Aguiar ◽  
Fernanda Proa Ferreira ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Nucleotide Excision Repair ◽  
Squamous Cell ◽  
Excision Repair ◽  
Repair Pathway ◽  
Nucleotide Excision ◽  
Nucleotide Excision Repair Pathway ◽  
Larynx Squamous Cell Carcinoma

Low etiologic fraction for human papillomavirus in larynx squamous cell carcinoma

Oral Oncology ◽  
2016 ◽  
Vol 61 ◽  
pp. 55-61 ◽  
Author(s):  
M. Taberna ◽  
C. Resteghini ◽  
B. Swanson ◽  
R.K.L. Pickard ◽  
B. Jiang ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Human Papillomavirus ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Larynx Squamous Cell Carcinoma ◽  
Etiologic Fraction

Study of the efficacy of 5 ALA-mediated photodynamic therapy on human larynx squamous cell carcinoma (Hep2c) cell line

Laser Physics ◽  
2010 ◽  
Vol 20 (7) ◽  
pp. 1673-1678 ◽  
Author(s):  
A. Khursid ◽  
M. Atif ◽  
S. Firdous ◽  
S. S. Z. Zaidi ◽  
R. Salman ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Photodynamic Therapy ◽  
Cell Carcinoma ◽  
Cell Line ◽  
Squamous Cell ◽  
Human Larynx ◽  
Larynx Squamous Cell Carcinoma
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