scholarly journals Serum Folate Levels and Intake of Folate, VB2, and VB6 Are Inversely Associated with Symptoms in Japanese Male Patients with Psychiatric Disorders

2011 ◽  
Vol 64 (4) ◽  
pp. 229-238
Author(s):  
Ritsuna Noguchi ◽  
Mami Hiraoka ◽  
Yoh Jinnouchi ◽  
Hiromi Kitahara ◽  
Yoshinori Watanabe ◽  
...  
Author(s):  
L. Scalfi ◽  
M. Marra ◽  
V. Zurlo ◽  
G. di Biase ◽  
C Lanzettab,A. Caldara ◽  
...  

2015 ◽  
Vol 8 (3) ◽  
pp. 171-176 ◽  
Author(s):  
Naoki WADA ◽  
Hiromichi IUCHI ◽  
Masafumi KITA ◽  
Kazumi HASHIZUME ◽  
Seiji MATSUMOTO ◽  
...  

1982 ◽  
Vol 42 (1) ◽  
pp. 21-29 ◽  
Author(s):  
Hitoshi Kukita ◽  
Yoichi Imamura ◽  
Mareomi Hamada ◽  
Tadafumi Joh ◽  
Tatsuo Kokubu

1996 ◽  
Vol 7 (6) ◽  
pp. 443-444 ◽  
Author(s):  
M Uno ◽  
T Deguchi ◽  
H Komeda ◽  
M Yasuda ◽  
M Tamaki ◽  
...  

A significant association of Mycoplasma genitalium with non-gonococcal urethritis has been reported, but the prevalence of this mycoplasma in men with gonococcal urethritis has not been so well studied. In this study, we examined urethral swab specimens from 45 Japanese male patients with gonococcal urethritis for the presence of M. genitalium by using a polymerase chain reaction-based assay. We also sought Chlamydia trachomatis by an enzyme immunoassay Chlamydiazyme . Of the 45 specimens, 2 4.4 were positive for the mycoplasma and 12 26.7 were positive for C. trachomatis. The findings suggest that M. genitalium may be a cause not only of non-gonococcal urethritis but also of postgonococcal urethritis.


2013 ◽  
Vol 40 (8) ◽  
pp. 1374-1378 ◽  
Author(s):  
Wako Urano ◽  
Atsuo Taniguchi ◽  
Eisuke Inoue ◽  
Chieko Sekita ◽  
Naomi Ichikawa ◽  
...  

Objective.To validate the association between genetic polymorphisms and gout in Japanese patients, and to investigate the cumulative effects of multiple genetic factors on the development of gout.Methods.Subjects were 153 Japanese male patients with gout and 532 male controls. The genotypes of 11 polymorphisms in the 10 genes that have been indicated to be associated with serum uric acid levels or gout were determined. The cumulative effects of the genetic polymorphisms were investigated using a weighted genotype risk score (wGRS) based on the number of risk alleles and the OR for gout. A model to discriminate between patients with gout and controls was constructed by incorporating the wGRS and clinical factors. C statistics method was applied to evaluate the capability of the model to discriminate gout patients from controls.Results.Seven polymorphisms were shown to be associated with gout. The mean wGRS was significantly higher in patients with gout (15.2 ± 2.01) compared to controls (13.4 ± 2.10; p < 0.0001). The C statistic for the model using genetic information alone was 0.72, while the C statistic was 0.81 for the full model that incorporated all genetic and clinical factors.Conclusion.Accumulation of multiple genetic factors is associated with the development of gout. A prediction model for gout that incorporates genetic and clinical factors may be useful for identifying individuals who are at risk of gout.


2004 ◽  
Vol 138 (5) ◽  
pp. 788-798 ◽  
Author(s):  
Takaaki Hayashi ◽  
Satoshi Omoto ◽  
Tomokazu Takeuchi ◽  
Kenichi Kozaki ◽  
Yasuo Ueoka ◽  
...  

2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
Alberto Fragasso ◽  
Clara Mannarella ◽  
Angela Ciancio ◽  
Oronzo Scarciolla ◽  
Nicoletta Nuzzolese ◽  
...  

Background. Measurement of serum cobalamin (Cbl) levels is the standard investigation for assessing vitamin B12 deficiency. Falsely increased values of Cbl can be caused by alcoholic liver disease. Measurement of total vitamin B12 serum levels might be misleading in alcoholics, because a tissue metabolic deficiency is possible even with normal serum Cbl levels. Holotranscobalamin (HoloTC), the Cbl metabolically active fraction, is considered as a better index of vitamin B12 deficiency.Methods. For assessing vitamin B12 status, we evaluated 22 adult alcoholic male patients by measuring in parallel serum Cbl, serum folate and red blood cell folate levels, HoloTC levels by the AxSYM assay.Results. HoloTC values were reduced in 3 alcoholics with borderline-low Cbl values. Significant positive correlations were found between serum Cbl and HoloTC levels, serum Cbl and gamma-glutamyl transpeptidase (GGT).Conclusion. HoloTC measurement is a useful option for assessing vitamin B12 status in alcoholics, particularly in the subjects with borderline Cbl values and may be considered an early marker of vitamin B12 deficiency.


Sign in / Sign up

Export Citation Format

Share Document