scholarly journals Mitral Valve Plasty in the Active Phase of Infective Endocarditis with Intracerebral Mycotic Aneurysms and Abscesses in the Brain and Lower Limb

2007 ◽  
Vol 36 (1) ◽  
pp. 19-22
Author(s):  
Hiroshi Kagawa ◽  
Kazuhiro Hashimoto ◽  
Yoshimasa Sakamoto ◽  
Hiroshi Okuyama ◽  
Shinichi Ishii ◽  
...  
2011 ◽  
Vol 19 (2) ◽  
pp. 149-153 ◽  
Author(s):  
Tadashi Omoto ◽  
Takeo Tedoriya ◽  
Masaya Oi ◽  
Naoko Nagai ◽  
Tadamasa Miyauchi ◽  
...  

2012 ◽  
Vol 23 (3) ◽  
pp. e67-e68 ◽  
Author(s):  
Ji Hyeon Park ◽  
Hye Ryoun Jang ◽  
Jung Eun Lee ◽  
Wooseong Huh ◽  
Dae Joong Kim ◽  
...  

The manifestation of infective endocarditis often resembles vasculitis. Approximately one in five infective endocarditis cases are referred initially to a nephrologist because of abnormal renal function or abnormal urinalysis; therefore, infection should be ruled out before diagnosing vasculitis.A case involving a patient with infective endocarditis who presented with migrating skin lesions, renal infarction and multiple pseudoaneurysms is reported. Echocardiography revealed mitral valve vegetation and viridans streptococci were identified in peripheral blood cultures. Although mitral valve annuloplasty and an aneurysm ligation operation were performed with proper antibiotic treatment, the remaining mycotic aneurysm progressed and caused neurological complications. The patient was cured completely after reoperation.


2011 ◽  
Vol 40 (2) ◽  
pp. 72-76
Author(s):  
Atsushi Shimizu ◽  
Hiroyuki Nakajima ◽  
Hiroaki Osada ◽  
Atsushi Nagasawa ◽  
Masahisa Kyogoku

Author(s):  
S.G. Weeks ◽  
C.J. Doig ◽  
C. Silva ◽  
R.N. Auer ◽  
C. Power ◽  
...  

Background:Infective endocarditis is associated with serious neurological sequelae.Objective:Here, we report a patient with Staphylococcus aureus endocarditis, secondary to congenital heart disease, with subacute onset of multiple neurological complications.Results:Despite prompt antibiotic treatment with rapid sterilization of blood cultures, the patient died with brain herniation within 96 hours of admission. Neuropathological examination showed intraparenchymal hemorrhages, mycotic aneurysms, micro-abscesses and septic arteritis with accompanying infarction. Immunocytochemical studies revealed enhanced CD45 and GFAP immunoreactivity, together with adenosine A1 receptor detection on macrophages and microglia.Conclusion:Infective endocarditis is associated with multiple neuropathological lesions, which may contribute to its poor clinical outcome and activation of cells of monocyte-microglial lineage throughout the brain.


2016 ◽  
Vol 43 (1-2) ◽  
pp. 59-67 ◽  
Author(s):  
Ajay Malhotra ◽  
Joseph Schindler ◽  
Brian Mac Grory ◽  
Stacy Y. Chu ◽  
Teddy S. Youn ◽  
...  

Objective: Patients with infective endocarditis (IE) frequently experience cerebral insults, and neurological involvement in IE has been reported to herald a worse prognosis. In this manuscript, we describe a distinctive pattern of findings on susceptibility-weighted imaging (SWI) sequences in subjects with IE. Methods: Patients with IE who underwent SWI MRI at an academic hospital from 2009 to 2014 were retrospectively analyzed. The pattern of findings was compared to SWI findings in groups of subjects with cerebral amyloid angiopathy (CAA) or severe hypertension. Results: Sixty-six subjects with IE were included; 64 (94%) had microhemorrhages and the average number per patient was 21.5. In 11 (17%) patients, microhemorrhages were the only neuroimaging abnormality. The majority of microhemorrhages were between 1 and 3 mm. In a direct comparison of gradient-echo T2* (GRE-T2*) and SWI, many microhemorrhages in this size range were not detected by GRE-T2*. Microhemorrhages in IE involved every part of the brain with a significant predilection for the cerebellum. This pattern was distinct from that seen in hypertension or CAA. Small subarachnoid hemorrhage or meningeal siderosis were also frequently detected in IE, but were not associated with mycotic aneurysms. Interpretation: SWI is a sensitive diagnostic technique for detecting infectious cerebral angiopathy in subjects with IE, producing a pattern of microhemorrhages that were distinct from other common microangiopathies.


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