scholarly journals Tocolytic treatment and childhood allergic disorders: The Japan Environment and Children’s Study

2021 ◽  
Author(s):  
Tsuyoshi Murata ◽  
Hirotaka Isogami ◽  
Karin Imaizumi ◽  
Toma Fukuda ◽  
Hyo Kyozuka ◽  
...  
Keyword(s):  
Lower Incidence ◽  
Developmental Disorders ◽  
Reference Group ◽  
Group Differences ◽  
Obstetric Outcomes ◽  
Maternal Characteristics ◽  
Term Births ◽  
Allergic Disorders ◽  
Tocolytic Agents ◽  
Childhood Developmental Disorders

Background: This study aimed to evaluate differences in maternal characteristics and obstetric and childhood outcomes between term births according to the use of tocolytic treatment. Methods: This study analyzed the data of the participants enrolled in the Japan Environment and Children’s Study between 2011 and 2014. Data of 63,409 women with singleton births after 37 weeks of gestation were analyzed. We compared maternal characteristics, obstetric outcomes, and childhood outcomes between term births with tocolytic treatment and those without tocolytic treatment. Multiple logistic regression was used to calculate adjusted odds ratios for childhood outcomes with significant between-group differences in the univariable analysis for term births with tocolytic agents, with term births without tocolytic agents as the reference group. Results: In term births with tocolytic agents, participants had significantly younger age, leaner body mass index, higher oxidative stress during pregnancy, shorter pregnancy period, lighter neonatal birth weight, lower incidence of gestational diabetes mellitus, higher incidence of preterm premature rupture of membrane, higher rates of cesarean section, lower incidence of meconium-stained amniotic fluid during pregnancy, and higher incidence of childhood allergic disorders. The incidence of childhood developmental disorders showed no significant between-group differences. The adjusted odds ratio for childhood allergic disorders in term births with tocolytic agents was 1.09 (95% confidence interval, 1.04-1.14). Conclusions: This study found no significant association between tocolytic treatment and the incidence of childhood developmental disorders in children with term births. However, tocolytic treatment showed an association with a slightly increased incidence of childhood allergic disorders.

Exploring the origins of developmental disorders

2005 ◽  
Vol 47 (7) ◽  
pp. 436-436 ◽  
Author(s):  
AD Flouris ◽  
BE Faught ◽  
J Hay ◽  
J Cairney
Keyword(s):  
Developmental Disorders

Trends, perinatal characteristics, and medical conditions in pervasive developmental disorders

2006 ◽  
Vol 48 (11) ◽  
pp. 896 ◽  
Author(s):  
Pascale Guillem ◽  
Christine Cans ◽  
Vincent Guinchat ◽  
Marc Ratel ◽  
Pierre-Simon Jouk
Keyword(s):  
Pervasive Developmental Disorders ◽  
Developmental Disorders ◽  
Medical Conditions

Risk of venous thromboembolism following surgical treatment of superficial venous incompetence

VASA ◽  
2017 ◽  
Vol 46 (6) ◽  
pp. 484-489 ◽  
Author(s):  
Tom Barker ◽  
Felicity Evison ◽  
Ruth Benson ◽  
Alok Tiwari
Keyword(s):  
Venous Thromboembolism ◽  
Varicose Vein ◽  
Lower Incidence ◽  
Varicose Veins ◽  
Secondary Data ◽  
Foam Sclerotherapy ◽  
Increased Risk ◽  
Significant Difference ◽  
Chi Squared ◽  
One Year

Abstract. Background: The invasive management of varicose veins has a known risk of post-operative deep venous thrombosis and subsequent pulmonary embolism. The aim of this study was to evaluate absolute and relative risk of venous thromboembolism (VTE) following commonly used varicose vein procedures. Patients and methods: A retrospective analysis of secondary data using Hospital Episode Statistics database was performed for all varicose vein procedures performed between 2003 and 2013 and all readmissions for VTE in the same patients within 30 days, 90 days, and one year. Comparison of the incidence of VTEs between procedures was performed using a Pearson’s Chi-squared test. Results: In total, 261,169 varicose vein procedures were performed during the period studied. There were 686 VTEs recorded at 30 days (0.26 % incidence), 884 at 90 days (0.34 % incidence), and 1,246 at one year (0.48 % incidence). The VTE incidence for different procedures was between 0.15–0.35 % at 30 days, 0.26–0.50 % at 90 days, and 0.46–0.58 % at one year. At 30 days there was a significantly lower incidence of VTEs for foam sclerotherapy compared to other procedures (p = 0.01). There was no difference in VTE incidence between procedures at 90 days (p = 0.13) or one year (p = 0.16). Conclusions: Patients undergoing varicose vein procedures have a small but appreciable increased risk of VTE compared to the general population, with the effect persisting at one year. Foam sclerotherapy had a lower incidence of VTE compared to other procedures at 30 days, but this effect did not persist at 90 days or at one year. There was no other significant difference in the incidence of VTE between open, endovenous, and foam sclerotherapy treatments.

Infants at risk of autism and developmental disorders: Establishing early social skills.

2017 ◽  
Vol 22 (1) ◽  
pp. 6-22 ◽  
Author(s):  
Hayley Neimy ◽  
Martha Pelaez ◽  
Jacqueline Carrow ◽  
Katerina Monlux ◽  
Jonathan Tarbox
Keyword(s):  
At Risk ◽  
Social Skills ◽  
Developmental Disorders
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