scholarly journals An extremely rare case of concurrent BRAF V600E mutation driven hairy cell leukemia and melanoma: Case report and review of literature

2017 ◽  
Vol 7 (3) ◽  
pp. 13-19 ◽  
Author(s):  
Amir Ghorbani-Aghbolaghi ◽  
Mirna Lechpammer ◽  
Saba Fatima Ali ◽  
Nam K. Ku ◽  
Denis Dwyre ◽  
...  
Keyword(s):  
Case Report ◽  
Hairy Cell Leukemia ◽  
Rare Case ◽  
Braf V600e Mutation ◽  
Braf V600e ◽  
Hairy Cell ◽  
Review Of Literature ◽  
Cell Leukemia ◽  
Melanoma Case

CD5 positive hairy cell leukemia: A rare case report with brief review of literature

2016 ◽  
Vol 90 (5) ◽  
pp. 467-472 ◽  
Author(s):  
Dharmendra Jain ◽  
Pranav Dorwal ◽  
Smeeta Gajendra ◽  
Amit Pande ◽  
Simmi Mehra ◽  
...  
Keyword(s):  
Case Report ◽  
Hairy Cell Leukemia ◽  
Rare Case ◽  
Hairy Cell ◽  
Review Of Literature ◽  
Cell Leukemia ◽  
Rare Case Report

Specific skin lesions in hairy cell leukemia at presentation: case report and review of literature

2009 ◽  
Vol 27 (2) ◽  
pp. 559-561 ◽  
Author(s):  
N. Čolović ◽  
M. Peruničić ◽  
V. Jurišić ◽  
M. Čolović
Keyword(s):  
Case Report ◽  
Hairy Cell Leukemia ◽  
Skin Lesions ◽  
Hairy Cell ◽  
Review Of Literature ◽  
Cell Leukemia

Identification of the BRAF V600E mutation in Japanese patients with hairy cell leukemia and related diseases using a quenching probe method

2018 ◽  
Vol 108 (4) ◽  
pp. 416-422
Author(s):  
Hidekazu Itamura ◽  
Masaru Ide ◽  
Akemi Sato ◽  
Naoko Sueoka-Aragane ◽  
Eisaburo Sueoka ◽  
...  
Keyword(s):  
Hairy Cell Leukemia ◽  
Japanese Patients ◽  
Braf V600e Mutation ◽  
Probe Method ◽  
Braf V600e ◽  
Hairy Cell ◽  
Cell Leukemia ◽  
Quenching Probe

scholarly journals Hairy cell leukemia with CCND1/IGH fusion gene and BRAF V600E mutation

2020 ◽  
Vol 13 ◽  
pp. 100197 ◽  
Author(s):  
Zaid Abdel Rahman ◽  
Firas Muwalla ◽  
Liuyan Jiang ◽  
James Foran
Keyword(s):  
Hairy Cell Leukemia ◽  
Fusion Gene ◽  
Braf V600e Mutation ◽  
Braf V600e ◽  
Hairy Cell ◽  
Cell Leukemia

scholarly journals Both variant and IGHV4-34–expressing hairy cell leukemia lack the BRAF V600E mutation

Blood ◽  
2012 ◽  
Vol 119 (14) ◽  
pp. 3330-3332 ◽  
Author(s):  
Liqiang Xi ◽  
Evgeny Arons ◽  
Winnifred Navarro ◽  
Katherine R. Calvo ◽  
Maryalice Stetler-Stevenson ◽  
...  
Keyword(s):  
B Cell ◽  
Hairy Cell Leukemia ◽  
Poor Prognosis ◽  
Braf V600e Mutation ◽  
Braf V600e ◽  
Hairy Cell ◽  
Cell Leukemia ◽  
Wild Type ◽  
Ighv Gene ◽  
Gene Usage

Abstract Recently, the BRAF V600E mutation was reported in all cases of hairy cell leukemia (HCL) but not in other peripheral B-cell neoplasms. We wished to confirm these results and assess BRAF status in well-characterized cases of HCL associated with poor prognosis, including the immunophenotypically defined HCL variant (HCLv) and HCL expressing the IGHV4-34 immunoglobulin rearrangement. Fifty-three classic HCL (HCLc) and 16 HCLv cases were analyzed for BRAF, including 5 HCLc and 8 HCLv expressing IGHV4-34. BRAF was mutated in 42 (79%) HCLc, but wild-type in 11 (21%) HCLc and 16 (100%) HCLv. All 13 IGHV4-34+ HCLs were wild-type. IGHV gene usage in the 11 HCLc BRAF wild-type cases included 5 IGHV4-34, 5 other, and 1 unknown. Our results suggest that HCLv and IGHV4-34+ HCLs have a different pathogenesis than HCLc and that a significant minority of other HCLc are also wild-type for BRAF V600.

Real-time detection of BRAF V600E mutation from archival hairy cell leukemia FFPE tissue by nanopore sequencing

2017 ◽  
Vol 45 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Davide Vacca ◽  
Valeria Cancila ◽  
Alessandro Gulino ◽  
Giosuè Lo Bosco ◽  
Beatrice Belmonte ◽  
...  
Keyword(s):  
Real Time ◽  
Hairy Cell Leukemia ◽  
Braf V600e Mutation ◽  
Ffpe Tissue ◽  
Braf V600e ◽  
Nanopore Sequencing ◽  
Hairy Cell ◽  
Cell Leukemia ◽  
Real Time Detection
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